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Eye and Vision 2018年第1期5卷 91-101页

作者： jean-claude Mwanza Joshua L.Warren Donald L.Budenz Department of Ophthalmology School of MedicineUniversity of North Carolina at Chapel HillChapel HillNCUSA Department of Biostatistics Yale UniversityNew HavenCTUSA

Optical coherence tomography(OCT)has moved to the forefront of imaging modalities in the management of glaucoma and retinal *** is modifying how glaucoma and glaucoma progression are diagnosed clinically and augmenting our understanding of the *** provides multiple parameters from various anatomic areas for glaucoma diagnosis,evaluation of treatment efficacy,and progression *** the use of multiple parameters has increased the likelihood of detecting early structural changes,diagnosing glaucoma in early stages is often challenging when the damages are subtle and not apparent on OCT scans,in addition to the fact that assessment of OCT parameters often yields conflicting *** promising approach is to combine multiple individual parameters into a composite parameter from the same test to improve diagnostic accuracy,sensitivity,and *** review presents current evidence regarding the value of spectral domain OCT composite parameters in diagnosing early glaucoma.

关键词： Optical coherence tomography Combination of parameters Early glaucoma

Efficient unidirectional polarization-controlled excitation of surface plasmon polaritons

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Light(Science & Applications) 2014年第1期3卷 100-105页

作者： Anders Pors Michael G Nielsen Thomas Bernardin jean-claude Weeber Sergey I Bozhevolnyi Department of Technology and Innovation University of Southern DenmarkOdenseDenmark LICB UMR 6303 CNRS–University of BurgundyF-21078 DijonFrance

Efficient excitation of surface plasmon polaritons(SPPs)remains one of the most challenging issues in areas of plasmonics related to information communication *** particular,combining high SPP excitation efficiency and acceptance of any polarization of incident light appeared to be impossible to attain due to the polarized nature of *** we demonstrate plasmonic couplers that represent arrays of gap SPP resonators producing upon reflection two orthogonal phase gradients in respective linear polarizations of incident *** couplers are thereby capable of efficiently converting incident radiation with arbitrary polarization into SPPs that propagate in orthogonal directions dictated by the phase *** couplers operate at telecom wavelengths and feature the coupling efficiency of,25%for either of two linear polarizations of incident radiation and directivity of SPP excitation exceeding *** further demonstrate that an individual wavelength-sized unit cell,representing a meta-scatterer,can also be used for efficient and polarization sensitive SPP excitation in compact plasmonics circuits.

关键词： gap surface plasmons metamaterials metasurfaces surface plasmon polaritonsgap surface plasmons metamaterials metasurfaces surface plasmon polaritons

Covalent functionalization/polycarboxylation of tungsten disulfide inorganic nanotubes （INTs-WS2）

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Nano Research 2015年第5期8卷 1454-1463页

作者： Daniel Raichman David A. Strawser jean-paul Lellouche Department of Chemistry Nanomaterials Research Center Institute of Nanotechnology & Advanced Materials Bar-Ilan University Ramat-Gan 5290002 Israel

Inorganic nanotubes of tungsten disulfide （INTs-WS2） are insoluble in common solvents and practically inert, hindering their usefulness in both research and commercial applications. The covalent attachment of functional species onto the surface of INT-WS2 is a critical first step in realizing the potential that INT-WS2 offer for high-performance materials and products. Although a few attempts have been reported regarding preparing modified nanotubes, only a limited range of surface functionalities is possible with these methods. We have developed a versatile method, based on a modified, highly electrophilic acidic Vilsmeier- Haack reagent, to produce covalently bonded, polycarboxylated functional WS2 nanotubes that are dispersible in polar liquids, including water. The surface polycarboxylated shell provides a means for additional derivatization, enabling matching compatibility of derivatized nanotubes to both hydrophobic and hydrophilic materials. Nanocomposites incorporating derivatized INT-WS2 are expected to show improved properties as a result of enhanced interfacial compatibility, made possible by the large number of classes of functionalization available through the initial polycarboxylation step.

关键词： tungsten disulfide nanotubes inorganic nanotube of tungsten disulfide(INT-WS2) Vilsmeier-Haack reagents polycarboxylation inorganic nanotube functionalization

Profile of retinal diseases in adult patients attending two major eye clinics in Kinshasa,the Democratic Republic of Congo

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International Journal of Ophthalmology(English edition) 2020年第10期13卷 1652-1659页

作者： Nelly N.Kabedi David L.Kayembe jean-claude Mwanza Departmemt of Ophthalmology School of MedicineUniversity of KinshasaKinshasa XIDemocratic Republic of Congo Department of Ophthalmology School of MedicineUniversity of North Carolina at Chapel HillNC 27599USA

AIM:To determine the frequency and types of retinal diseases and the extend of the related visual loss in adult patients attending two public eye clinics of Kinshasa,Democratic Republic of ***:Review of medical records of patients with retinal diseases seen in the major eye clinics in Kinshasa,the University Hospital of Kinshasa(UHK)and Saint Joseph Hospital(SJH),from January 2012 to December *** and diagnoses were retrieved and *** measures were frequency and prevalence of retinal diseases,blindness and low ***:A total of 40965 patients aged 40 y or older were examined during this period in both *** these,1208 had retinal disease,giving a 3-year and an annual prevalence of 3%and 1%,*** age was 61.7±10.7 y,and 55.8%of the patients were *** hypertension(68.1%)and diabetes(43.3%)were the most common systemic *** retinopathy(41.8%),diabetic retinopathy(37.9%),age-related macular degeneration(AMD;14.6%),and chorioretinitis and retinal vein occlusion(7.3%each)were the most common retinal diseases,with 3-year prevalence rates of 1.3%,1.0%,0.43%,and 0.21%*** low vision and blindness were present in 26.8%and 8.4%of the patients at *** causes of low vision and blindness were diabetic retinopathy(14.8%),AMD(4.9%),retinal detachment(2.8%),and retinal vein occlusion(2.5%).The prevalence was significantly higher among males than females,and at the UHK than ***:Retinal diseases are common among Congolese adult patients attending eye clinics in *** cause a significant proportion of low vision and blindness.

关键词： retinal disorders Kinshasa,Democratic Republic of Congo sub-Saharan Africa pattern

Integrating Functional Status Information into Knowledge Graphs to Support Self-Health Management

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Data Intelligence 2023年第3期5卷 636-662页

作者： Mauro Dragoni Tania Bailoni Ivan Donadello jean-claude Martin Helena Lindgren Fondazione Bruno Kessler TrentoItaly Free University of Bolzano BolzanoItaly LISN-CNRS Universite Paris SaclayParisFrance Umea University UmeaSweden

Functional Status Information(FSI)describes physical and mental wellness at the whole-person *** includes information on activity performance,social role participation,and environmental and personal factors that affect the well-being and quality of *** and analyzing this information is critical to address the needs for caring for an aging global population,and to provide effective care for individuals with chronic conditions,multi-morbidity,and *** knowledge graphs(PKGs)represent a suitable way for meaning in a complete and structured way all information related to people's FSI and reasoning over them to build tailored coaching solutions supporting them in daily life for conducting a healthy *** this paper,we present the development process related to the creation of a PKG by starting from the HeLis ontology in order to enable the design of an Al-enabled system with the aim of increasing,within people,the self-awareness of their own functional *** particular,we focus on the three modules extending the HeLis ontology aiming to represent(i)enablers and(ii)barriers playing potential roles in improving(or deteriorating)own functional status and(iii)arguments driving the FSI collection ***,we show how these modules have been instantiated into real-world scenarios.

关键词： Knowledge Graph Personal Healthcare Functional Status Enablers Barriers Arguments

Signs as Creators of Thought Processes

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Language and Semiotic Studies 2022年第1期8卷 105-113页

作者： jean-paul Bronckart University of Geneva Switzerland

This paper elaborates on some of Saussure’s reflections on the structure of signs,and the role these signs play in the constitution of conscious *** the notes of La double essence,Saussure argued that the sign “creates” and “guides” thought,but as part of a reflection that is both complex and *** clarify this position and examine its relevance,we first analyze the general conception of the status of signs and semiotics,that Saussure developed in his Course *** then examine the way in which,in the twentieth century,the problem of how human thought is constituted was tackled by Piaget and ***,drawing on the notes of La double Essence,we try to highlight the arguments that led Saussure to adopt the position quoted below,and we will show how Saussure’s approach provides decisive arguments in support of the social interactionist position inherited from Vygotsky.

关键词： development semiotics sign thought process Vygotsky

Effects of water-borne copper on the gills and hepatopancreas of Macrobrachium rosenbergii

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Integrative Zoology 2008年第4期3卷 299-310页

作者： Na LI Qiang MA Jian YANG Yunlong ZHAO jean-claude BROCHON School of Life Science East China Normal UniversityShanghaiChina Key Laboratory of Ecological Environment and Resources of Inland Fisheries Freshwater Fisheries Research CenterChinese Academy of Fishery SciencesWuxiChina National Research Center Laboratory of Biotechnology and Application Genetic PharmacologyEcole Normale Supérieure CachanCachan cedexFrance

We focused on elucidating the toxic effects of water-borne copper on the giant freshwater prawn Macrobrachium *** seven days of exposure to copper(Cu2+)at concentrations ranging from 0.01 mg L–1 to 0.5 mg L–1,three isozymes,malate dehydrogenase,alkaline phosphatase and esterase,were analyzed and compared using polyacrylamide electrophoresis(PAGE)and biochemical *** results indicated that the electrophoretic patterns of the isozymes showed a copper-concentration-related *** doses of copper stimulated strong expression of the three *** patterns of malate dehydrogenase and alkaline phosphatase gradually became weaker or even lost as the level of copper *** contrast,esterase patterns exhibited an increased molecular heterogeneity at higher copper concentrations.A transmission electron microscope was used to study ultrastructure differences in the gills and hepatopancreas of ***,and the results showed significant structural damage at increased levels of copper compared with the control *** basement mem-branes and mitochondira in the gills were seriously damaged,the cuticle electron density distribution was not homogeneous,and an infolded basement membrane,circularized nucleus,disintegrated nuclear membrane,and decreased mitochondria number and size were observed in the ***,flowing out of karyoplasms,partly falling microvilli,decreased mitochondrion,partly disappeared mitochondrial cristae,and a thinned matrix were observed in the *** findings indicate that exposure to elevated copper levels might damage the ultrastructure of the gills and hepatopancreas of *** and might further weaken their normal physical *** were quite sensitive to environmental stress and changes in isozyme elctrophoretic patterns might be effective biomarkers of environmental contamination.

关键词： copper gills hepatopancreas isozymes Macrobrachium rosenbergii polyacrylamide electrophoresis.

Accurate surface potential determination in Schottky diodes by the use of a correlated current and capacitance voltage *** to n-InP

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Journal of Semiconductors 2011年第10期32卷 39-43页

作者： Ali Ahaitouf Abdelaziz Ahaitouf jean paul Salvestrini Hussein Srour Laboratoire Signaux Systemes et Composants DGE Faculty of Sciences and TechnologyUniversite Sidi Mohammed Ben AbdellahP.O.Box 2202FES Morocco LIMAO Faculte polydisciplinaire de Taza Universite Sidi Mohammed Ben Abdellah de FesBP 1223 Taza-GareMorocco Laboratoire Materiaux Optiques Photonique et SystemesEA 4423Universite Paul Verlaine-MetzSupelec2 rue E.Belin57070 MetzFrance

Based on current voltage（I-Vg） and capacitance voltage（C-Vg） measurements,a reliable procedure is proposed to determine the effective surface potential Vd（Vg） in Schottky *** the framework of thermionic emission,our analysis includes both the effect of the series resistance and the ideality factor,even voltage dependent. This technique is applied to n-type indium phosphide（n-InP） Schottky diodes with and without an interfacial layer and allows us to provide an interpretation of the observed peak on the C-Vg *** study clearly shows that the depletion width and the flat band barrier height deduced from C-Vg,which are important parameters directly related to the surface potential in the semiconductor,should be estimated within our approach to obtain more reliable information.

关键词： Schottky diode interface states surface potential ideality factor barrier height capacitance voltage current measurements

Analysis of the Progressive Collapse Behavior of the RC Frame Structures Reinforced by High-Performance Composite Material

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Analysis of the Progressive Collapse Behavior of the RC Fram...

作者： Evina Mvondo jean claude（艾维）东南大学

学位级别：硕士

本文旨在对钢-连续纤维复合筋(Steel Fiber Composite Bar,简称SFCB)加固钢筋混凝土框架抗连续倒塌性能进行分析研究,利用软件SAP2000.V15.0.1,建立了 22mx18m,层高16m的典型钢筋混凝土框架结构模型,进行传统钢筋加固和SFCB筋加固下结... 详细信息

本文旨在对钢-连续纤维复合筋(Steel Fiber Composite Bar,简称SFCB)加固钢筋混凝土框架抗连续倒塌性能进行分析研究,利用软件SAP2000.V15.0.1,建立了 22mx18m,层高16m的典型钢筋混凝土框架结构模型,进行传统钢筋加固和SFCB筋加固下结构性能的对比;根据相关SFCB筋材性能研究,确定软件中力学性能的调整系数,以更接近筋材的实际情况;利用备用路径法对模型分别进行角柱,中柱,内柱拆除的三种情况,对剩余结构抗连续倒塌性能进行分析研究,得到不同同情况的下的结论;研究SFCB筋二次刚度和塑性铰旋转能力对结构抗连续倒塌的影响,在软件中,通过调整系数的方法,不断提高二次刚度和塑性铰旋转能力,对比分析两种材料性能对结构的作用,得出相应结;根据所有的研究结果,对SFCB筋加固混凝土框架结构抗连续倒塌性能进行评估,并提出相关建议

关键词：连续倒塌混凝土框架结构 SFCB 二次刚度塑性铰

Effect of the synthesis route on the structural and dielectric properties of SrBi1.8Y0.2Nb2O9 ceramics

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International Journal of Minerals,Metallurgy and Materials 2018年第11期25卷 1304-1312页

作者： Mohamed Afqir Amina Tachafine Didier Fasquelle Mohamed Elaatmani jean-claude Carru Abdelouahad Zegzouti Mustapha El Hammioui Laboratoire des Sciences des Matériaux Inorganiques et leurs Applications Facultédes Sciences SemlaliaUniversitéCadi AyyadMarrakech 40000Maroc Unite de Dynamique et Structure des Materiaux Moleculaires Universite du Littoral-Cote d’OpaleCalais 62100France Laboratoire de recherche sur la réactivitédes matériaux et l’optimisation des procédés Facultédes Sciences SemlaliaUniversitéCadi Ayyad 40000MarrakechMaroc

This work is devoted to the synthesis and characterization of yttrium-doped SrBi_2Nb_2O_9 ceramics prepared by three methods: solid state reaction, co-precipitation, and hydrothermal. Multiple characterizations, specifically scanning electron microscopy(SEM), X-ray powder diffraction(XRD), and Fourier transform infrared spectroscopy(FTIR), were used to validate the structural feature. The crystallite size was estimated by Scherrer's formula and the Williamson–Hall plot. The effect of the process on the band intensities of the FTIR spectra was investigated. The crystallite size and microstructure of ceramics prepared from different synthesis processes were strongly influenced by the sinterability. SEM images revealed nanograin ceramics for materials prepared by co-precipitation and hydrothermal methods and micrograin ceramics prepared by the solid state method. The synthesized compounds underwent phase transitions at 480–465°C. The dielectric and electrical properties of these Y-doped SrBi_2Nb_2O_9 ceramics appear to be dependent on the grain size.

关键词： Aurivillius,synthesis routes crystallite size microstructure dielectric