检索结果-南通市图书馆

Differences in oxidative stress dependence between gastric adenocarcinoma subtypes

World Journal of Gastroenterology 2006年第7期12卷 1005-1012页

作者： Brigitte Bancel JacauesEstève jean-christophe souquet Shinya Toyokuni Hiroshi Ohshima Brigitte Pignatelli Hospital de la Croix-Rousse Department of PathologyLyonFrance Centre Hospital de la Croix-Rousse Department of GastroenterologyLyonFrance Department of Pathology and Biology of Diseases Graduate School of MedicineKyoto UniversityKyotoJapan Brigitte Pignatelli International Agency for Research on Cancer.Endogenous Risk Factors GroupLyon.France Clinical Epidemiology Unit Department of Medical InformationHospices Civils de LyonFrance

AIM： To investigate the extent of oxidative stress in preneoplastic and neoplastic gastric mucosa in relation to their pathological criteria and histological subtypes. METHODS： A total of 104 gastric adenocarcinomas from 98 patients （88 infiltrative and 16 intraepithelial tumors） were assessed immunohistochemically for expression of iNOS and occurrence of nitrotyrosine （NTYR）-containing proteins and 8-hydroxy-2＇-deoxyguanosine （8-OH- dG）-containing DNA, as markers of NO production and damages to protein and DNA. RESULTS： Tumor cells staining for iNOS, NTYR and 8-OH-dG were detected in 41%, 62% and 50% of infiltrative carcinoma, respectively. The three markers were shown for the first time in intraepithelial carcinoma. The expression of iNOS was significantly more frequent in tubular carcinoma （TC） compared to diffuse carcinoma （DC）（54% vs 18%; P=0.008） or in polymorphous carcinoma （PolyC）（54% vs 21% ; P=0.04）. NTYR staining was obviously more often found in TC than that in PolyC （72% vs 30% ; P=0.03）. There was a tendency towards a higher rate of iNOS staining when distant metastasis （pM） was present. In infiltrative TC, the presence of oxidative stress markers was not significantly correlated with histological grade, density of inflammation, the depth of infiltration （pT）, lymph nodes dissemination （pN） and pathological stages （pTNM）.CONCLUSION： The iNOS-oxidative pathway may play an important role in TC, but moderately in PolyC and DC. DNA oxidation and protein nitration occur in the three subtypes. Based on the significant differences of NTYR levels, TC and PolyC appear as two distinct subtypes.

关键词： Gastric neoplasms Nitric oxide synthase Hpylori Nitrotyrosine 8-hydroxydeoxyguanosine Oxidative stress

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Lateral ring compression test applied to a small caliber steel jacket:Identification of a constitutive model

引用

Defence Technology（防务技术） 2024年第6期36卷 133-148页

作者： Yann Coget Yael Demarty christophe Czarnota Anthony Bracq jean-Sebastien Brest Alexis Rusinek French-German Research Institute of Saint-Louis 5 Rue Du General Cassagnou68300 Saint-LouisFrance Laboratoire d'Etude des Microstructures et de Mecanique des Materiaux(LEM3) CNRSUniversite de LorraineArts&Metiers ParisTechF-57000 MetzFrance

The evolution of threats and scenarios requires continuous performance improvements of ballistic protections for armed *** a modeling point of view,it is necessary to use sufficiently precise material behavior models to accurately describe the phenomena observed during the impact of a projectile on a protective *** this context,the goal of this paper is to characterize the behavior of a small caliber steel jacket by combining experimental and numerical *** experimental method is based on the lateral compression of ring specimens directly machined from the thin and small *** speeds and temperatures are considered in a quasi-static regime in order to reveal the strain rate and temperature dependencies of the tested *** Finite Element Updating Method(FEMU)is *** results are coupled with an inverse optimization method and a finite element numerical model in order to determine the parameters of a constitutive model representative of the jacket *** of the present model are verified against experimental results and a parametric study as well as a discussion on the identified material parameters are *** results indicate that the strain hardening parameter can be neglected and the behavior of the thin steel jacket can be described by a modeling without strain hardening sensitivity.

关键词： Full metal jacket ammunition Lateral ring compression Inverse identification Numerical simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bridging Continents,Shaping Futures

引用

China Today 2024年第10期73卷 20-21页

作者： jean-christophe DESLARZES Board of the Adecco Group

The combined strengths of China and Europe can build a workforce that is well-prepared for the future and capable of driving economic *** highly anticipated China-Europe Talent Forum 2024 provides us with an invaluable platform to discuss and enhance the strong ties between China and Europe,focusing on the future of talent *** relationship between China and Europe has long been marked by mutual respect and a deep commitment to collaboration in various sectors,including trade,technology,education,and culture.

关键词： mutual driving education

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Inducing neuronal regeneration and differentiation via the BDNF/ TrkB signaling pathway: a key target against neurodegenerative diseases?

引用

Neural Regeneration Research 2024年第3期19卷 495-496页

作者： Mirjana Antonijevic Patrick Dallemagne christophe Rochais Normandie University UNICAENCERMNCaenFrance

Brain-derived neurotrophic factor(BDNF)is one of the neurotrophins,a specific polypeptide growth factor,which plays a crucial role in the proliferation,differentiation,survival,and death of neurons and non-neuronal *** is not only essential to maintain the balance between death on one side and survival of neurons on the other,but also it mediates additional higher-order activities such as learning,memory,and *** is initially synthesized as a precursor protein,proBDNF,that can be secreted as it is or it can be cleaved intracellularly by furin and proconvertases,or extracellularly by extracellular proteases such as matrix metalloprotease-9 and matrix metalloprotease-2,or plasmin to give mature BDNF.

关键词： death diseases degenerative

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Immunobiodiversity:Conserved and specific immunity across land plants and beyond

引用

Molecular Plant 2024年第1期17卷 92-111页

作者： Baptiste Castel Karima El Mahboubi christophe Jacquet Pierre-Marc Delaux Laboratoire de Recherche en Sciences Végétales(LRSV) Universitéde ToulouseCNRSUPSToulouse INPCastanet-TolosanFrance

Angiosperms represent most plants that humans cultivate,grow,and ***,angiosperms are only one of five major land plant *** a whole lineage,plants also include algal *** these clades represent a tremendous genetic diversity that can be investigated to reveal the evolutionary history of any given *** this review,we describe the current model of the plant immune system,discuss its evolution based on the recent literature,and propose future directions for the *** angiosperms,plant–microbe interactions have been intensively studied,revealing essential cell surface and intracellular immune receptors,as well as metabolic and hormonal defense *** diversity at the genomic and functional levels demonstrates the conservation of these pathways across land plants,some of which are beyond *** basis of the conserved mechanisms,lineage-specific variations have occurred,leading to diversified reservoirs of immune *** rare cases,this diversity has been harnessed and successfully transferred to other species by integration of wild immune receptors or engineering of novel forms of receptors for improved resistance to *** propose that exploring further the diversity of immune mechanisms in the whole plant lineage will reveal completely novel sources of resistance to be deployed in crops.

关键词： evolution MPMI immunity plant evoMPMI symbiosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bound and Resonating Multiquark Configurations

引用

Chinese Physics Letters 2024年第8期41卷 8-12页

作者： jean-Marc Richard Institut de Physique des 2 Infinis de Lyon Université Claude Bernard(Lyon 1) CNRS-IN2P34 rue Enrico Fermi69622 VilleurbanneFrance

We review the predictions of quark models for multiquark configurations that are bound or resonant states,and compare different methods for estimating the properties of resonances.

关键词： quark Configuration resonant

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multi-source information fusion:Progress and future

引用

Chinese Journal of Aeronautics 2024年第7期37卷 24-58页

作者： Xinde LI Fir DUNKIN jean DEZERT School of Automation Southeast UniversityNanjing 210008China Nanjing Center for Applied Mathematics Nanjing 211135China Key Laboratory of Measurement and Control of CSE Ministry of EducationNanjing 210096China Southeast University Shenzhen Research Institute Shenzhen 518063China Information Modeling and Processing Department ONERAPalaiseau 92320France

Multi-Source Information Fusion(MSIF),as a comprehensive interdisciplinary field based on modern information technology,has gained significant research value and extensive application prospects in various domains,attracting high attention and interest from scholars,engineering experts,and practitioners *** achieving fruitful results in both theoretical and applied aspects over the past five decades,there remains a lack of comprehensive and systematic review articles that provide an overview of recent development in *** light of this,this paper aims to assist researchers and individuals interested in gaining a quick understanding of the relevant theoretical techniques and development trends in MSIF,which conducts a statistical analysis of academic reports and related application achievements in the field of MSIF over the past two decades,and provides a brief overview of the relevant theories,methodologies,and application domains,as well as key issues and challenges currently ***,an analysis and outlook on the future development directions of MSIF are presented.

关键词： Multi-sensor system Information fusion Artificial intelligence Pattern recognition Human-machine integration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microplastics and microbiota:Unraveling the hidden environmental challenge

引用

World Journal of Gastroenterology 2024年第16期30卷 2191-2194页

作者： jean Demarquoy Universitéde Bourgogne Institut Agro-DijonDijon 21000France

This editorial explores the intricate relationship between microplastics(MPs)and gut microbiota,emphasizing the complexity and environmental health *** gut microbiota,a crucial component of gastrointestinal health,is examined in the context of potential microbial degradation of ***,dysbiosis induced by MPs emerges as a consensus,disrupting the balance of gut microbiota and decreasing *** mechanisms triggering dysbiosis,including physical interactions and chemical composition,are under *** research addresses the consequences of MPs on immune function,nutrient metabolism,and overall host *** bidirectional relationship between MPs and gut microbiota has significant implications for environmental and human *** uncertainties,MPs negatively impact gut microbiota and *** research is essential to unravel the complex interactions and assess the long-term consequences of MPs on both environmental and human well-being.

关键词： Microplastics Microbiota Gut Dysbiosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Design and Experimental Testing of a Moving Coil Actuator with Compensation Coil

引用

CSEE Journal of Power and Energy Systems 2024年第2期10卷 707-716页

作者： Boyuan Yin Xianwu Zeng John Frederick Eastham Emelie Nilsson jean-francois Rouquette jean Rivenc Ludovic Ybanez Xiaoze Pei Department of Electronics&Electrical Engineering University of BathBathBA27AYUnited Kingdom Airbus UpNext BlangnacFrance Airbus CRT BlangnacFrance Department of Mechanical Engineering University of BathBathBA27AYUnited Kingdom

Hydrogen-powered electric aircraft have attracted significant interests aiming to achieve decarbonization *** DC electric networks are facing great challenges in DC fault protection *** interrupters are widely used in low voltage and medium voltage power systems due to being environmentally friendly with low *** this paper a moving coil actuator with compensation coils for a vacuum interrupter,as part of a hybrid direct current circuit breaker,is designed and experimentally *** coils are used to improve operating speed compared with original moving coil *** between four possible connections of compensation coils and original moving coil actuator are carried *** results show comparisons between different connections of actuator coils in terms of opening time and coil current with a range of pre-charged capacitor *** performance of each actuator connection is also *** actuator with compensation coils is shown to have a higher current rising rate and achieve faster opening speed,which is a critical requirement for electric aircraft network *** parallel connection actuator achieves the highest opening speed within 3.5 ms with capacitor voltage of 50 V.

关键词： Circuit breaker compensation coil moving coil actuator vacuum interrupter

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tanaka Formula and Local Time for a Class of Interacting Branching Measure-valued Diffusions

引用

Acta Mathematica Sinica,English Series 2024年第4期40卷 1059-1098页

作者： Donald A.DAWSON jean VAILLANCOURT Hao WANG School of Mathematics and Statistics Carleton UniversityOttawaCanada Department of Decision Sciences HECMontrealCanada Department of Mathematics University of OregonEugeneUSA

We construct superprocesses with dependent spatial motion(SDSMs)in Euclidean spaces R^(d)with d≥1 and show that,even when they start at some unbounded initial positive Radon measure such as Lebesgue measure on R^(d),... 详细信息

关键词： Measure-valued diffusions stochastic partial differential equations superprocesses branching processes local time Tanaka formula

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：