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Exposure to Electromagnetic Fields from Mobile Phones and Fructose consumption Coalesce to Perturb Metabolic Regulators AMPK/SIRT1-UCP2/FOXO1 in Growing Rats

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Biomedical and Environmental Sciences 2023年第11期36卷 1045-1058页

作者： Ruchi Tripathi Sanjay Kumar Banerjee jay Prakash Nirala Rajani Mathur Department of Pharmacology Delhi Institute of Pharmaceutical Sciences & ResearchDelhi Pharmaceutical Sciences and Research University(DPSR-U))New DelhiINDIA Drug Discovery Research Centre Translational Health Science and Technology InstituteFaridabadINDIA Department of Biotechnology National Institute of Pharmaceutical Education and ResearchGuwahatiINDIA School of Environmental Sciences Jawaharlal Nehru UniversityNew DelhiINDIA

Objective In this study,the combined effect of two stressors,namely,electromagnetic fields(EMFs)from mobile phones and fructose consumption,on hypothalamic and hepatic master metabolic regulators of the AMPK/SIRT1-UCP2/FOXO1 pathway were elucidated to delineate the underlying molecular mechanisms of insulin *** Weaned Wistar rats(28 days old)were divided into 4 groups:Normal,Exposure Only(ExpO),Fructose Only(FruO),and Exposure and Fructose(EF).Each group was provided standard laboratory chow ad libitum for 8 ***,the control groups,namely,the Normal and FruO groups,had unrestricted access to drinking water and fructose solution(15%),***,the respective treatment groups,namely,the ExpO and EF groups,received EMF exposure(1,760 MHz,2 h/day x 8 weeks).In early adulthood,mitochondrial function,insulin receptor signaling,and oxidative stress signals in hypothalamic and hepatic tissues were assessed using western blotting and biochemical *** In the hypothalamic tissue of EF,SIRT1,FOXO 1,p-PI3K,p-AKT,ComplexⅢ,UCP2,MnSOD,and catalase expressions and OXPHOS and GSH activities were significantly decreased(P<0.05)compared to the Normal,ExpO,and FruO *** hepatic tissue of EF,the p-AMPKα,SIRT1,FOXO1,IRS1,p-PI3K,ComplexⅠ,Ⅱ,Ⅲ,Ⅳ,Ⅴ,UCP2,and MnSOD expressions and the activity of OXPHOS,SOD,catalase,and GSH were significantly reduced compared to the Normal group(P<0.05).Conclusion The findings suggest that the combination of EMF exposure and fructose consumption during childhood and adolescence in Wistar rats disrupts the closely interlinked and multi-regulated crosstalk of insulin receptor signals,mitochondrial OXPHOS,and the antioxidant defense system in the hypothalamus and liver.

关键词： EMF-mobile phone Fructose Childhood-adolescence Insulin receptor signal Mitochondrial OxPHOS Antioxidant system Hypothalamic insulin resistance Hepatic insulin resistance

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Cross Trajectory Gaussian Process Regression Model for Battery Health Prediction

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Journal of Modern Power Systems and Clean Energy 2021年第5期9卷 1217-1226页

作者： Jianshe Feng Xiaodong Jia Haoshu Cai Feng Zhu Xiang Li jay Lee NSF I/UCR Center for Intelligent Maintenance Systems Department of Mechanical EngineeringUniversity of CincinnatiCincinnatiUSA

Accurate battery capacity prediction is important to ensure reliable battery operation and reduce the ***,the complex nature of battery degradation and the presence of capacity regeneration phenomenon render the prediction task very *** address this problem,this paper proposes a novel and efficient algorithm to predict the battery capacity trajectory in a multi-cell *** proposed method is a new variant of Gaussian process regression(GPR)model,and it utilizes similar trajectories in the historical data to enhance the prediction of desired capacity *** importantly,the proposed method adds no extra computation cost to the standard *** demonstrate the effectiveness of the proposed method,validation tests on two different battery datasets are implemented in the case *** prediction results and the computation cost are carefully benchmarked with cuttingedge GPR approaches for battery capacity prediction.

关键词： Prognostic lithium-ion battery Gaussian process regression state of health

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Wiley's Remediation Technologies Handbook: Major Contaminant Chemicals and Chemical Groups

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2004年

作者： jay H. Lehr

ISBN: (数字)9780471655473

ISBN: (纸本)9780471455998

Wiley's Remediation Technologies Handbook: Major Contaminant Chemicals and Chemical Groups , extracted from the Enviroglobe database, consists of 368 chemicals and chemical groups. This book lists in alphabetical order these chemical and chemical groups along with the numerous technologies, many of which are patented, or trademarked techniques, to remediate them. A short description of each of these technologies is provided along with appropriate references. Wiley's Remediation Technologies Handbook: Major Contaminant Chemicals and Chemical Groups : Covers the most important chemical and chemical groups that are found to pollute the environment, and the ways to remediate them. Gives succinct abstract describing the numerous technologies used to clean-up a wide range of pollutants. Provides the uses and limitations of each technique. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

关键词： Hazardous wastes

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The Use of the Past to Shape the Present:Shifting Depictions of the Ancient World in Twentieth-Century American Cinema

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Fudan Journal of the Humanities and Social Sciences 2019年第1期12卷 61-78页

作者： Jacqueline E.jay History Department Eastern Kentucky UniversityKeith 323521 Lancaster Ave.RichmondKY 40475USA

The ancient film epic has its roots at the very dawn of cinema as a form of popular art and entertainment,with a number of early silent films drawing their plots from ancient Biblical and Classical sources,and the genre remains relevant in the early twenty-first *** film epics thus provide a useful lens through which to trace evolutions in film history and in western culture more *** paper analyzes seven American films spanning the early twentieth century to the early twenty-first century(Intolerance,Quo Vadis,The Egyptian,The Ten Com?***,Gladiator,300),identifying specific ways each film mirrors or challenges the time period in which it was produced.

关键词： Film history Ancient history Ancient film epic Intolerance D.W.Griffith Quo Vadis The Egyptian The Ten Commandments Cecil B.DeMille-Spartacus Stanley Kubrick Gladiator 300

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Directional chromosome walk by using RFLP data

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Chinese Science Bulletin 1996年第2期41卷 153-157页

作者：刘秋云 jay C. Dunlap Biotechnology Research Center Zhongshan University Guangzhou 510275 China Department of Biochemistry Dartmouth Medical School Hanowr NH 03756 USA

Chromosome walk is a very important technique in molecular genetics. Its applicationin molecular cloning becomes more and more extensive. However, in common practice wecannot determine the direction of a chromosome wa... 详细信息

关键词： chromosome walk RFLP crossover recombination rate.

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Simulation of mode conversion at the magnetopause

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Chinese Science Bulletin 2012年第12期57卷 1375-1383页

作者： LIN Yu JOHNSON jay WANG XueYi LU QuanMing Physics Department Auburn University Auburn 36849 USA Department of Geophysics and Planetary Science University of Science and Technology of China Hefei 230026 China princeton Plasma Physics Laboratory Princeton University Princeton 08543 USA

Two-dimensional(2-D)and three-dimensional(3-D)hybrid simulations are carried out for mode conversion from fast mode compressional wave to kinetic Alfvn waves(KAWs)at the inhomogeneous magnetopause *** cases in which the incident fast wave propagates in the xz plane,with the magnetopause normal along x and the background magnetic field pointing along z,the 2-D (xz)simulation shows that KAWs with large wave number kxρi～1 are generated near the Alfve′n resonance surface,whereρi is the ion Larmor *** nonlinear wave properties are manifest in the mode conversion *** of the driver frequency are *** a result of nonlinear wave interaction,the mode conversion region and its spectral width are *** the 3-D simulation,after this first stage of the mode conversion to KAWs with large kx,a subsequent generation of KAW modes of finite ky is observed in the later stage,through a nonlinear parametric decay *** the nonlinear cascade to ky can lead to massive transport at the magnetopause,the simulation results provide an effective transport mechanism at the plasma boundaries in space as well as laboratory plasmas.

关键词：模拟模式磁层顶等离子体边界模式转换非线性波非线性参数波动力学混合模拟

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Geochemical Modelling of Fluoride Concentration in Hard Rock Terrain of Madhya Pradesh, India

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Acta Geologica Sinica(English Edition) 2013年第5期87卷 1421-1433页

作者： jay Krishna THAKUR Prafull SINGH Sudhir Kumar SINGH Bijendra BHAGHEL Thakur International & Investment (P) Ltd. Amity Institute of Geo-Informatics and Remote Sensing (AIGIRS) Amity University K.Banerjee Centre of Atmospheric and Ocean Studies IIDS University of Allahabad Department of Earth Sciences Barkatullah University

The aim of the present study is to locate and decipher the groundwater quality, types, and hydrogeochemicai reactions, which are responsible for elevated concentration of fluoride in the Chhindwara district in Madhya Pradesh, India. Groundwater samples, quality data and other ancillary information were collected for 26 villages in the Chhindwara District, M.P. India during May 2006. The saturation index was computed for the selected samples in the region, which suggest that generally most of the minerals are saturated with respect to water. The concentration of fluoride in the region varies from 0.6 to 4.74 rag/l, which is much higher as per the national and international water quality standards. The study also reveals that the fluoride bearing rock formations are the main source of the higher concentration of fluoride in groundwater along with the conjuncture of land use change. Moreover, the area is a hard rock terrain and consists of fractured granites and amygdaloidal and highly jointed compact basalt acting as good aquifer, which is probably enriching the high content of fluoride in groundwater. High concentration of fluoride is found in deeper level of groundwater and it is possible due to rock-water interaction, which requires further detailed investigation. The highly alkaline conditions indicate fluorite dissolution, which works as a major process for higher concentration of fluoride in the study area. The results of this study will ultimately help in the identification of risk areas and taking measures to mitigate negative impacts related to fluoride pollution and toxicity.

关键词： Fluoride rock-water interaction saturation index Madhya Pradesh India

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Phenology-based delineation of irrigated and rain-fed paddy fields with Sentinel-2 imagery in Google Earth Engine

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Geo-Spatial Information Science 2021年第4期24卷 695-710页

作者： Daniel Marc G.dela Torre jay Gao Cate Macinnis-Ng Yan Shi School of Environment University of AucklandAucklandNew Zealand School of Biological Sciences University of AucklandAucklandNew Zealand

Paddy rice agriculture is practiced in both rain-fed and irrigated ecosystems in the ***,small farms are prevalent in the region,and current satellite-based mapping techniques do not distinguish between the two ecosystems at farm *** study developed an approach to rapidly map irrigated and rain-fed paddy rice in Iloilo,Philippines at 10 m resolutions using Google Earth *** approach used an ensemble of classifiers based on time-series vegetation indices to produce dry and wet seasonal maps for the entire *** showed a predominance of rain-fed rice areas in both seasons,with irrigated rice making up only onefourth of the total rice *** overall accuracy was achieved at 68%for the dry season and 75%for the wet season based on ground-acquired points and very high-resolution *** two types of paddies were classified at accuracies up to 87%.Furthermore,the land cover maps showed a strong agreement with the municipal *** resultant maps complement current official statistics and demonstrate the prowess of phenology-based mapping to create paddy inventories in a timely manner to inform food security and agricultural policies.

关键词： Phenology-based mapping paddy type Google Earth Engine Sentinel-2 rice mapping

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Geographic mapping of choroidal thickness in myopic eyes using 1050-nm spectral domain optical coherence tomography

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Journal of Innovative Optical Health Sciences 2015年第4期8卷 20-31页

作者： Qinqin Zhang Maureen Neitz jay Neitz Ruikang K.Wang Department of Bioengineering University of Washington SeattleWA 98195USA Department of Ophthalmology University of Washington SeattleWA 98104USA

Purpose:To provide a geographical map of choroidal thickness(CT)around the macular region armong subjects with low,moderate and high ***:20 myopic subjects(n=40 eyes)without other identified pathologies participated in this study:20 eyes of≤3 diopters(D)(low myopic),10 eyes between-3 and-6D(moderate myopic),and 10 eyes of≥6D(high myopic).The mean age of subjects was 30.2 years(±7.6 years;range,24 to 46 years).A 1050 nm spectral-domain optical coberence tomography(SD-OCT)system,operating at 120kHz imaging rate,was used in this study to simultaneously capture 3D anatomical images of the choroid and measure intraocular length(IOL)in the *** 3D OCT images of the choroid were segmented into superior,inferior,nasal and temporal quadrants,from which the CT was measured,representing radial distance between the outer retinal pigment epithelium(RPE)layer and inner scleral *** were made within concentric regjons centered at fovea centralis,extended to 5 mm away from fovea at 1 mm intervals in the nasal and temporal *** measured IOL was the distance from the anterior cornea surface to the RPE in alignment along the optical axis of the *** analysis was performed to evaluate CT at each geographic region and observe the relationship between CT and the degree of ***:For low myopic eyes,the IOL was measured at 24.619±0.016 *** CT(273.85±49.01μm)was greatest under fovea as is in the case of healthy *** to the fovea,the mean CT decreased rapidly along the nasal direction,reaching a minimum of 180.65±58.25 pum at 5 mm away from the *** was less of a change in thickness from the fovea in the temporal direction reaching a minimum of 234.25±42.27μ*** contrast to the low myopic eyes,for moderate and high myopic eyes,CTs were thickest in termnporal region(where CT=194.94±27.28 and 163±34.89μm,respectively).Like the low myopic eyes,moderate and high myopic eyes had thinnest CTs in the nasal region(wh

关键词： Choroidal thicknes myopia SDOCT geographic mapping

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Diffuse cystic lung diseases

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Frontiers of Medicine 2013年第3期7卷 316-327页

作者： jay H.Ryu Xinlun Tian Misbah Baqir Kaifeng Xu Division of Pulmonary and Critical Care Medicine Mayo ClinicRochesterMN 55905USA Division of Respiratory Medicine Peking Union Medical College HospitalBeijing 100730China

Diffuse cystic lung diseases are uncommon but can present a diagnostic challenge because increasing number of diseases have been associated with this *** in the lung is defined as a round parenchymal lucency with a well-defined thin wall(<2 mm thickness).Focal or multifocal cystic lesions include blebs,bullae,pneumatoceles,congenital cystic lesions,traumatic lesions,and several infectious processes such as coccidioidomycosis,Pneumocystis jiroveci pneumonia,and hydatid disease.“Diffuse”distribution in the lung implies involvement of all *** lung involvement with cystic lesions can be seen in pulmonary lymphangioleiomyomatosis,pulmonary Langerhans’cell histiocytosis,lymphoid interstitial pneumonia,Birt-Hogg-Dubésyndrome,amyloidosis,light chain deposition disease,honeycomb lung associated with advanced fibrosis,and several other rare causes including metastatic ***-resolution computed tomography of the chest helps define morphologic features of the lung lesions as well as their distribution and associated features such as intrathoracic *** the tempo of the disease process and clinical context with chest imaging findings serve as important clues to defining the underlying nature of the cystic lung disease and guide diagnostic evaluation as well as management.

关键词： cyst lung disease interstitial lung disease lymphangioleiomyomatosis Langerhans’cell histiocytosis Birt-Hogg-Dubésyndrome

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