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Incidence of surgical site infection in minimally invasive colorectal surgery

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 1121-1129页

作者： Lu-ting Ni ru Zhao Yi-ru Ye Yi-Ming Ouyang Xin chen Department of Surgery The First Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina

BACKGROUND Surgical site infection(SSI)is a common complication of colorectal *** invasive surgery notably reduces the incidence of *** study aimed to compare the incidences of SSI after robot-assisted colorectal surgery(RACS)vs that after laparoscopic assisted colorectal surgery(LACS)and to analyze associated risk factors for SSI in minimally invasive colorectal *** To compare the incidences of SSI after RACS and LACS,and to analyze the risk factors associated with SSI after minimally invasive colorectal *** Clinical data derived from patients who underwent minimally invasive colorectal surgery between October 2020 and October 2022 at the First Affiliated Hospital of Soochow University were *** in clinical characteristics and surgeryrelated information associated with RACS and LACS were compared,and possible risk factors for SSI were *** A total of 246 patients(112 LACS and 134 RACS)were included in the ***(17.5%)developed *** proportions of patients who developed SSI were similar in the two groups(17.9%vs 17.2%,P=0.887).Diabetes mellitus,intraoperative blood loss≥100 mL,and incision length were independent risk factors for *** additional risk factors included neoadjuvant therapy,lesion site,and operation *** There was no difference in SSI incidence in the RACS and LACS *** mellitus,intraoperative blood loss≥100 mL,and incision length were independent risk factors for postoperative SSI.

关键词： Colorectal surgery Minimally invasive surgery Surgical site infection

Investigating the Absorption and Desorption Behavior of Methylene Chloride in the Poly(aryl ether ketone) Film with Different Crystallinities

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Chinese Journal of Polymer Science 2024年第2期42卷 239-246,I0009页

作者： Hong-ru Yang Jin-Dong Zhang Dong-ting Gao Gang Liu Chun-Hai chen Jia-Nan Yao Center for Advanced Low-Dimension Materials State Key Laboratory for Modification of Chemical Fibers and Polymer MaterialsCollege of Materials Science and EngineeringDonghua UniversityShanghai201620China

Poly(aryl ether keton e)(PAEK) films with different crystallinities were obtained by controlling the cooling rate,which were subjected to the absorption and desorption of methylene chloride(CH_(2)Cl_(2)).We employed attenuated total reflection Fourier transform infrared(ATR-FTIR)spectroscopy analyses to investigate the diffusion behavior of CH_(2)Cl_(2) in PAEK films with different *** to the Fickian diffusion model,the calculated diffu sion coefficients of CH_(2)Cl_(2) in PAEK films were observed to decrease with increasing *** effect of CH_(2)Cl_(2)absorption and desorption on the mechanical properties of PAEK films with different crystallinity was further analyzed using tensile *** tensile tests exhibited that CH_(2)Cl_(2) has two concurrent effects:plasticization and solvent-induced *** scanning calorimetry(DSC) and wide-angle X-ray diffraction(WXRD) techniques further confirmed solvent-induced crystallization *** results would be beneficial to understand the solvent resistance of PAEK materials and consequently provide the practical application conditions of PAEK with a theoretical basis.

关键词： Poly(aryl ether ketone) Diffusion behavior Infrared spectra Solvent-induced crystallization Mechanical properties

Exercise-induced microbial changes in preventing type 2 diabetes

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Science China(Life Sciences) 2024年第5期67卷 892-899页

作者： ting Yao Hui Wang Kaiqing Lin ruwen Wang Shanshan Guo Peijie chen Hao Wu Tiemin Liu ru Wang School of Exercise and Health Shanghai Frontiers Science Research Base of Exercise and Metabolic HealthShanghai University of SportShanghai 200438China Department of Physiology and Pathophysiology School of Basic Medical SciencesXi’an Jiaotong University School of MedicineXi’an 710061China Shanghai Key Laboratory of Metabolic Remodeling and Health Institute of Metabolism&Integrative BiologyFudan UniversityShanghai 200433China State Key Laboratory of Genetic Engineering Human Phenome InstituteFudan Microbiome Centerand Department of Bariatric and Metabolic SurgeryHuashan HospitalFudan UniversityShanghai 201203China State Key Laboratory of Genetic Engineering Department of Endocrinology and MetabolismHuman Phenome Instituteand School of Life SciencesZhongshan HospitalFudan UniversityShanghai 200032China

The metabolic benefits associated with long-term physical activity are well appreciated and growing evidence suggests that it involves the gut *** we re-evaluated the link between exercise-induced microbial changes and those associated with prediabetes and *** found that the relative abundances of substantial amounts of diabetes-associated metagenomic species associated negatively with physical fitness in a Chinese athlete students *** additionally showed that those microbial changes correlated more with handgrip strength,a simple but valuable biomarker suggestive of the diabetes states,than maximum oxygen intake,one of the key surrogates for endurance ***,the causal relationships among exercise,risks for diabetes,and gut microbiota were explored based on mediation *** propose that the protective roles of exercise against type 2 diabetes are mediated,at least partly,by the gut microbiota.

关键词： gut microbiota body fat diabetes handgrip maximum oxygen intake

Exercise Prescription: Pioneering the “Third Pole” for Clinical Health Management

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Research 2024年第3期6卷 469-471页

作者： Zhiwen Luo ting Zhang Shiyi chen Department of Sports Medicine Huashan HospitalFudan University.Shanghai 200040.China Department of Integrative Medicine Huashan HospitalFudan UniversityShanghaiChina.

Originating from Western medicine,the concept of“exercise prescription”has gradually gained recognition and promotion in *** to the traditional medicinal prescription,exercise prescription offers scientific,individualized exercise recommendations to those willing or needing to use exercise as a means of treating ailments,preventing diseases,or enhancing physical constitution[1].This advice is prescribed formally,detailing elements such as the type of exercise,frequency,intensity,duration,and *** objectives are straightforward:to treat existing illnesses and to prevent potential *** specializing in sports medicine and qualified sports rehabilitation therapists can prescribe such exercise directives,ensuring that recipients get the most appropriate exercise *** prescription is suitable for a diverse demographic,from teenagers to the elderly,and from the health-conscious to those suffering from various chronic diseases.

关键词： prescription Pioneer prescribed

Efficacyand Safetyof Huashi Baidu Granules in Treating Patients with SARS-CoV-2Omicron Variant: A Single-Center Retrospective Cohort Study

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Chinese Journal of Integrative Medicine 2024年第2期30卷 107-114页

作者： chen Cai-yu ZHANG Wen XU Xiang-ru PU Yu-ting TU Ya-dan PENG Wei YAO Xuan ZHOU Shuang FANG Bang-jiang Department of Emergency Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai(200032)China Department of Classical Traditional Chinese Medicine Chongqing Hospital of Traditional Chinese MedicineChongqing(400021)China Acupuncture and Massage College Shanghai University of Traditional Chinese MedicineShanghai(201203)China Institute of Emergency and Critical Care Medicine Shanghai University of Traditional Chinese MedicineShanghai(200032)China

Objective:To evaluate the efficacy and safety of Huashi Baidu Granules(HSBD)in treating patients with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)Omicron ***:A single-center retrospective cohort study was conducted during COVID-19 Omicron epidemic in the Mobile Cabin Hospital of Shanghai New International Expo Center from April 1st to May 23rd,*** COVID-19 patients with asymptomatic or mild infection were assigned to the treatment group(HSBD users)and the control group(non-HSBD users).After propensity score matching in a 1:1 ratio,496 HSBD users of treatment group were matched by propensity score to 496 non-HSBD *** in the treatment group were administrated HSBD(5 g/bag)orally for 1 bag twice a day for 7 consecutive *** in the control group received standard care and routine *** primary outcomes were the negative conversion time of nucleic acid and negative conversion rate at day *** outcomes included the hospitalized days,the time of the first nucleic acid negative conversion,and new-onset symptoms in asymptomatic *** events(AEs)that occurred during the study were *** subgroup analysis was conducted in vaccinated(378 HSBD users and 390 non-HSBD users)and unvaccinated patients(118 HSBD users and 106 non-HSBD users).Results:The median negative conversion time of nucleic acid in the treatment group was significantly shortened than the control group[3 days(IQR:2-5 days)vs.5 days(IQR:4-6 days);P<0.01].The negative conversion rate of nucleic acid in the treatment group were significantly higher than those in the control group at day 7(91.73%vs.86.90%,P=0.014).Compared with the control group,the hospitalized days in the treatment group were significantly reduced[10 days(IQR:8-11 days)vs.11 days(IQR:10.25-12 days);P<0.01].The time of the first nucleic acid negative conversion had significant differences between the treatment and control groups[3 days(IQR:2-4 days)vs.5 days(IQR:

关键词： Huashi Baidu Granule severe acute respiratory syndrome coronavirus 2 Omicron variant retrospective cohort trial Chinese medicine

The δ^(15)N values of foxtail millet(Setaria italica)and common millet(Panicum miliaceum)are reliable indicators of manuring practices

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Science China Earth Sciences 2024年第9期67卷 2910-2923页

作者： Jishuai YANG Xiaoyan YANG ting YOU Fahu chen Key Scientific Research Base of Bioarchaeology in Cold and Arid Regions(National Cultural Heritage Administration) Key Laboratory of Western China’s Environmental Systems(Ministry of Education)College of Earth and Environmental SciencesLanzhou UniversityLanzhou 730000China Group of Alpine Paleoecology and Human Adaptation(ALPHA) State Key Laboratory of Tibetan Plateau Earth SystemResources and Environment(TPESRE)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems College of Pastoral Agriculture Science and TechnologyLanzhou UniversityLanzhou 730000China

Millet agriculture,which originated in northern China,alongside rice agriculture,have nurtured the Chinese *** manuring practices likely promoted and maintained sustainable millet agricultural production in the loess area of northern ***,ongoing controversy exists regarding the indicators of prehistoric manuring intensity of foxtail millet(Setaria italica)and common millet(Panicum miliaceum).Here,we present the results of pot and field fertilization experiments on two millet *** findings suggest that manuring can significantly increase the δ^(15)N values of foxtail millet,and its δ^(15)N values increase with increasing manuring *** δ^(15)N values of foxtail millet leaves are systematically greater than those of grains by approximately 1.6‰.Manuring could have a long-term residual impact on increasing the δ^(15)N values of soil and millet *** with previous crop fertilization experiment results,we propose that the impact of manuring on the δ^(15)N values of non-nitrogen-fixing crops is roughly *** δ^(15)N value and amount of manure are key factors determining the extent of change in plant δ^(15)N *** millet grain δ^(15)N values can serve as reliable indicators of manuring ***,we provide an interpretive framework for assessing the correlation between manuring levels and the δ^(15)N values of archaeological millet *** δ^(15)N values of ancient millet grains suggest widespread and intensive manuring practices in prehistoric millet agriculture in northern China,spanning from the early Yangshao period to the Longshan period.

关键词： Millet farming Manuring experiment Farming system Archaeobotany North China

Optimizing mechanical properties of HIPS fabricated with low-cost desktop 3D printers:investigating the impact of process parameters

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Advances in Manufacturing 2024年第2期12卷 379-395页

作者： Jin-ting Xu Guang-Wei Zhang Man-Man chen School of Automotive Engineering Dalian University of TechnologyDalian116024People’s Republic of China

Recently,low-cost desktop three-dimensional(3D)printers,employing the fused deposition modeling(FDM)technique,have gained widespread ***,most users cannot test the strength of printed parts,and little information is available about the mechanical properties of printed high-impact polystyrene(HIPS)parts using desktop 3D *** this study,the user-adjustable parameters of desktop 3D printers,such as crisscross raster orientation,layer thickness,and infill density,were *** experimental plans were designed using the Box-Behnken method,and tensile,3-point bending,and compression tests were carried out to determine the mechanical responses of the printed *** prediction models of the process parameters were regressed to produce the optimal combination of process *** experimental results showcase that the crisscross raster orientation has significant effects on the flexural and compression strengths,but not on the tensile *** an increase in the layer thickness,the tensile,flexural,and compression strengths first decreased and then increased,reaching their minimum values at approximately 0.16 mm layer *** addition,they all increased with an increase of infill *** was demonstrated that when the raster orientation,layer thickness,and infill density were 13.08°/–76.92°,0.09 mm,and 80%,respectively,the comprehensive mechanical properties of the printed HIPS were *** results can help end-users of desktop 3D printers understand the effects of process parameters on the mechanical properties,and offer practical suggestions for setting proper printing parameters for fabricating HIPS parts.

关键词： Desktop three-dimensional(3D)printers Fused deposition modeling(FDM) High-impact polystyrene(HIPS) Process parameters

Neuroimmune interactions and their roles in neurodegenerative diseases

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Fundamental Research 2024年第2期4卷 251-261页

作者： Bai-Rong chen ting Wu ting-Hui chen Yun Wang Neuroscience Research Institute and Department of Neurobiology School of Basic Medical SciencesKey Laboratory for NeuroscienceMinistry of Education/National Health Commission and State Key Laboratory of Natural and Biomimetic DrugsPeking UniversityBeijing 100083China PKU-IDG/McGovern Institute for Brain Research Peking UniversityBeijing 100871China

The nervous system possesses bidirectional,sophisticated and delicate communications with the immune *** neuroimmune interactions play a vitally important role in the initiation and development of many disorders,especially neurodegenerative *** scientific advancements have made tremendous progress in this field during the last few years,neuroimmune communications are still far from being *** organizing recent research,in this review,we discuss the local and intersystem neuroimmune interactions and their roles in Alzheimer’s disease,Parkinson’s disease and amyotrophic lateral *** these will help us gain a better understanding of the process of interplay inside the body and how the organism maintains *** will also facilitate a view of the diseases from a holistic,pluralistic and interconnected perspective,thus providing a basis of developing novel and effective methods to diagnose,intervene and treat diseases.

关键词： Nervous system Immune system Neuroimmune interactions Alzheimer’s disease Parkinson’s disease Amyotrophic lateral sclerosis

Metal-Free Synthesis of 2-Aminobenzothiazoles via I2-Catalyzed Tandem Cyclization Reaction of Amines and Carbon Disulfide

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Chinese Journal of Chemistry 2024年第8期42卷 846-852页

作者： ting chen Wei Feng ruitong Yang Shanping chen Guo-Jun Deng Key Laboratory for Green Organic Synthesis and Application of Hunan Province Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of EducationCollege of ChemistryXiangtan UniversityXiangtanHunan411105 China School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiangHunan453007 China

Comprehensive Summary,A convenient approach for the construction of 2-aminobenzothiazoles via I2-catalyzed tandem cyclization reaction of amines and carbon disulfide has been *** present approach starts from simple and readily available starting materials,affording a series of 2-aminobenzothiazoles in up to 89%yields under metal-free *** this work,C—H/N—H functionalization was achieved and multiple C-hetero bonds were successfully constructed in one pot.

关键词： Sulfur heterocycles C-H functionalization Cyclization Tandem reaction Transition-metal-free Amines lodine N-Heterocycles