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On the combined effect of soil fertility and topography on tree growth in subtropical forest ecosystems—a study from SE China

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Journal of Plant Ecology 2017年第1期10卷 111-127页

作者： Thomas Scholten philipp Goebes Peter Kühn Steffen Seitz Thorsten Assmann Jürgen Bauhus Helge Bruelheide Francois Buscot Alexandra Erfmeier Markus Fischer Werner Härdtle Jin-Sheng He Keping Ma Pascal A.Niklaus Michael Scherer-Lorenzen Bernhard Schmid Xuezheng Shi Zhengshan Song Goddert von Oheimb Christian Wirth Tesfaye Wubet Karsten schmidt Department of Geosciences Soil Science and GeomorphologyUniversity of TübingenRümelinstraße 19-2372070 TübingenGermany Institute of Ecology Leuphana University LüneburgScharnhorststr.121335 LüneburgGermany Faculty of Forest and Environmental Sciences SilvicultureUniversity of FreiburgTennenbacherstraße 479085 Freiburg im BreisgauGermany Institute of Biology/Geobotany and Botanical Garden Martin Luther University Halle WittenbergAm Kirchtor 106108 HalleGermany German Centre for Integrative Biodiversity Research(iDiv)Halle-Jena-Leipzig Deutscher Platz 5e04103 LeipzigGermany Helmholtz Centre for Environmental Research UFZ Theodor-Lieser-Straße 406120 HalleGermany Department of Plant Sciences University of BernAltenbergrain 213013 BernSwitzerland Peking University No.5 Yiheyuan RoadHaidian DistrictBeijing 100871China Institute of Botany Chinese Academy of SciencesNo.20 NanxincunXiangshanBeijing 100093China Institute of Evolutionary Biology and Environmental Studies University of ZürichWinterthurerstrasse 1908057 ZürichSwitzerland Faculty of Biology Department of GeobotanyUniversity of FreiburgSchänzlestraße 179104 FreiburgGermany Institute of Soil Science Chinese Academy of SciencesNo.71 East Beijing RoadNanjingChina TU Dresden Biodiversity and Nature ConservationPienner Straße 701737 TharandtGermany Department of Systematic Botany and Functional Biodiversity University of LeipzigJohannisallee 2104103 LeipzigGermany

Aims The aim of our research was to understand small-scale effects of topography and soil fertility on tree growth in a forest biodiversity and ecosystem functioning(BEF)experiment in subtropical SE *** Geomorphometric terrain analyses were carried out at a spatial resolution of 5×5 *** samples of different depth increments and data on tree height were collected from a total of 566 plots(667 m2 each).The soils were analyzed for carbon(soil organic carbon[SOC]),nitrogen,acidity,cation exchange capacity(CEC),exchangeable cations and base saturation as soil fertility *** plots were classified into geomorphological *** of variance and linear regressions were applied to all terrain,soil fertility and tree growth *** Findings In general,young and shallow soils and relatively small differences in stable soil properties suggest that soil erosion has truncated the soils to a large extent over the whole area of the *** explains the concurrently increasing CEC and SOC stocks downslope,in hollows and in ***,colluvial,carbon-rich sediments are missing widely due to the convexity of the footslopes caused by uplift and removal of eroded sediments by adjacent *** results showed that soil fertility is mainly influenced by ***-Carlo flow accumulation(MCCA),curvature,slope and aspect significantly affected soil ***,soil fertility was affected by the different geomorphological positions on the experimental sites with ridge and spur positions showing lower exchangeable base cation contents,especially potassium(K),due to *** geomorphological effect of soil fertility is most pronounced in the topsoil and decreases when considering the subsoil down to 50 cm *** soil fertility attributes affect tree height after 1-2 years of growth,among which C stocks proved to be most important while pH_(KCl)and CEC only played minor ***,soil acidity and a hig

关键词： soil fertility topography soil erosion matter transport biodiversity DSM carbon stocks tree forest BEF-China China

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SLM2 Is A Novel Cardiac Splicing Factor Involved in Heart Failure due to Dilated Cardiomyopathy

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Genomics, Proteomics & Bioinformatics 2022年第1期20卷 129-146页

作者： Jes-Niels Boeckel Maximilian Mobius-Winkler Marion Muller Sabine Rebs Nicole Eger Laura Schoppe Rewati Tappu Karoline E.Kokot Jasmin M.Kneuer Susanne Gaul Diana M.Bordalo Alan Lai jan Haas Mahsa Ghanbari philipp Drewe-Boss Martin Liss Hugo A.Katus Uwe Ohler Michael Gotthardt Ulrich Laufs Katrin Streckfuss-Bomeke Benjamin Meder Department of Cardiology Angiology and PneumologyUniversity Hospital HeidelbergD-69120 HeidelbergGermany Klinik und Poliklinik fur Kardiologie Universitatskrankenhaus LeipzigD-04103 LeipzigGermany German Center for Cardiovascular Research(DZHK) Partner site HeidelbergD-69120 HeidelbergGermany Clinic for General and Interventional Cardiology/Angiology Herz-und Diabeteszentrum NRWRuhr-Universitat BochumD-32545 Bad OeynhausenGermany Department of Cardiology and Pneumology University HospitalGeorg-August University GoettingenD-37075 GoettingenGermany German Center for Cardiovascular Research(DZHK) Partner site GoettingenD-37075 GoettingenGermany Berlin Institute for Medical Systems Biology Max Delbruck Center for Molecular Medicine in the Helmholtz AssociationD-10115 BerlinGermany Institute of Biology Humboldt Universitat zu BerlinD-10099 BerlinGermany Neuromuscular and Cardiovascular Cell Biology Max Delbruck Center for Molecular Medicine in the Helmholtz AssociationD-13092 BerlinGermany German Center for Cardiovascular Research(DZHK) Partner site BerlinD-10117 BerlinGermany Stanford Genome Technology Center Department of GeneticsStanford Medical SchoolPalo AltoCA 94304USA

Alternative mRNA splicing is a fundamental process to increase the versatility of the *** humans,cardiac mRNA splicing is involved in the pathophysiology of heart *** in the splicing factor RNA binding motif protein 20(RBM20) cause severe forms of *** identify novel cardiomyopathy-associated splicing factors,RNA-seq and tissue-enrichment analyses were performed,which identified up-regulated expression of Sam68-Like mammalian protein 2(SLM2) in the left ventricle of dilated cardiomyopathy(DCM) *** the human heart,SLM2 binds to important transcripts of sarcomere constituents,such as those encoding myosin light chain2(MYL2),troponin 13(TNNI3),troponin T2(TNNT2),tropomyosin 1/2(TPM1/2),and titin(TTN).Mechanistically,SLM2 mediates intron retention,prevents exon exclusion,and thereby mediates alternative splicing of the mRNA regions encoding the variable proline-,glutamate-,valine-,and lysine-rich(PEVK) domain and another part of the I-band region of *** summary,SLM2 is a novel cardiac splicing regulator with essential functions for maintaining cardiomyocyte integrity by binding to and processing the mRNAs of essential cardiac constituents such as titin.

关键词： Splicing Titin Dilated cardiomyopathy KHDRBS3 SLM2

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General Solution for Unsteady Natural Convection Flow with Heat and Mass in the Presence of Wall Slip and Ramped Wall Temperature

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Communications in Theoretical Physics 2019年第6期71卷 647-657页

作者： Saeed Ullah jan Sami Ul Haq Syed Inayat Ali Shah Ilyas Khan Muhammad Atif Khan Faculty of Mathematics and Statistics Ton Duc Thang UniversityHo Chi Minh CityVietnam Department of Mathematics Islamia College UniversityPeshawar25000Pakistan Department of Mathematics Kohat University of Science&TechnologyKohat26000Pakistan

This work is focused on the effect of heat and mass transfer with unsteady natural convection flow of viscous fluid along with ramped wall temperature under the assumption of the slip wall condition at the boundary. Analytical solutions are obtained by using Laplace transformation to the non-dimensional set of governing equations containing velocity, temperature and concentration. Moreover, the expression for skin-friction is derived by differentiating the analytical solutions of fluid velocity. Numerical tables for Skin-friction, Sherwood number and Nusselt-number are examined. For the physical aspects of the flow, we use various values of involved physical parameters such as Prandtl number(Pr), slip parameter(η), schmidt number(Sc), buoyancy ratio parameter(N), Sherwood number(Sh), and time(t). Additionally, the general solutions are plotted graphically and a comprehensive theoretical section of numerical discussions is included.

关键词： slip boundary condition heat and mass transfer skin-friction

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Water Efflux in Red Blood Cells of Sickle Cell Patients under Spontaneous Deoxygenation

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Journal of Biosciences and Medicines 2016年第12期4卷 152-161页

作者： Manuel Arsenio Lores Guevara Yulianela Mengana Torres Juan Carlos García Naranjo Andrés Ramírez Aguilera Lidia Clara Suárez Beyrio María Altagracia Marichal Felue Teresa Simón Brada jan philippé Centro de Biofí sica Mé dica Santiago de Cuba Cuba Hospital General “Juan Bruno Zayas Alfonso” Santiago de Cuba Cuba Department of Clinical Chemistry Immunology and Microbiology Ghent University Ghent Belgium

The water transport through Red Blood Cells (RBC) membrane has been previously studied in Sickle Cell Disease (SCD) using oxygenated RBC or under complete deoxygenation. In this work, the water efflux in RBC of sickle cell patients was studied under spontaneous deoxygenation conditions. With that purpose, a magnetic resonance method was used to evaluate the water exchange time (τe) and the permeability through the erythrocyte membrane (P) measuring the spin-spin relaxation time (T2) in doped and non-doped RBC. Carr-Purcell-Meiboon-Gill (CPMG) pulse sequence was used to measure T2 in a magnetic resonance console coupled to one homogeneous magnet system (0.095 T). An increase of the water transport in RBC from sickle cell patients was observed and characterized with a τe value of 15.2 ± 0.8 ms. The abnormal activation of the Psickle, Gardos, and potassium chloride cotransporter channels starting from deoxygenation, as well as, the possible appearance of new pores due to the increase of the hemoglobin-membrane interaction, are suggested to explain this abnormal transport phenotype. The change of the water volume to surface ratio (V/S) in the sickle cells is also suggested to be considered in P calculation under deoxygenation. The results obtained in this work increase the fundamental knowledge about molecular mechanism involved in SCD and could be useful in the development of new methods for diagnostic and treatment evaluation.

关键词： Red Blood Cells Water Permeability Nuclear Magnetic Relaxation Sickle Cell Disease

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Atmosphere, ocean and lithosphere interaction as a possible drive of earthquake triggering

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Geodesy and Geodynamics 2020年第6期11卷 442-454页

作者： Victor Volkov jan Mrlina Mstislav Dubrov Vladimir Smirnov Sergey Golovachev Vaclav Polak schmidt Institute of Physics of the Earth of the Russian Academy of Sciences MoscowRussian Federation Institute of Geophysics of the Czech Academy of Sciences PrahaCzech Republic Kotel'nikov Institute of Radioengineering and Electronics of the Russian Academy of Sciences FryazinoRussian Federation

The comparison of tiltmeter and strainmeter data in the periods of the strongest earthquakes with tropical cyclone activities in the World Ocean during januarye April 2014 is *** features of the observed co-seismic tilt and strain processes are consistent with the results obtained for the strongest events during *** time-frequency data analysis and the comparison of the analysis results with the anomalous geomagnetic and ionospheric activity come to an agreement with the observed *** obtained results have allowed the triggering mechanism of seismicity to be *** process begins as spatial and temporal swings of the regions of tropical cyclone origins and the basins of their *** powerful cyclone development accompanies a wide range of earthquake precursory phenomena,including abnormal behavior of ultra-wideband(0.002 m Hz-3 Hz)Earth’s oscillations,which can be recorded at far distances up to 1000-10,000 *** daily dissipation energy of the most powerful tropical cyclone(hurricane,typhoon)is estimated to have same order of magnitude as the energy released by an event of Mw 7-9,as well,atmospheric depressions are big enough to trigger a forthcoming strong *** triggering mechanism could be caused by quasi-static and timedependent surface loading that produces vertical tension and shear *** loading affects the seafloor and coastline where they fall close to the adjacent tectonic plate boundaries.

关键词： Tilt and strain Tropical cyclone Earthquake Hurricane

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Artificial intelligence in pancreatic surgery:current applications

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Journal of Pancreatology 2023年第2期6卷 74-81页

作者： Christoph Kuemmerli Fabian Rössler Caroline Berchtold Michael C.Frey Alexander Studier-Fischer Amila Cizmic jan philipp Jonas Thilo Hackert Felix Nickel Philip C.Müller Department of Surgery Clarunis-University Centre for Gastrointestinal and Liver DiseasesBaselSwitzerland Swiss HPB and Transplantation Center Department of Surgery and TransplantationUniversity Hospital ZurichZurichSwitzerland Department for General Visceral and Vascular SurgeryKantonsspital BadenBadenSwitzerland Department of General Visceral and Transplantation SurgeryHeidelberg University HospitalHeidelbergGermany Department of General Visceral and Thoracic SurgeryUniversity Medical Center Hamburg-EppendorfHamburgGermany

Surgery plays a central role in the treatment of benign and malignant pancreatic *** intelligence(AI)is an important upcoming technology to support surgeons in pre-,intra-,and postoperative diagnosis,decision-making and training toward an optimized patient *** AI applications show a promising role in the evaluation of preoperative images for prediction of malignancy and resectability,intraoperative decision support,surgical training as well as a postoperative risk stratification to per-sonalize the management of *** scoping review summarizes the most up to date developments of AI in pancreatic surgery with the highest available level of evidence.

关键词： Artificial intelligence Image-guidance Machine learning Pancreas neoplasms Pancreatic ductal carcinoma Personalized medicine Surgery

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IPY计划“大西洋中部海岭系（Mohns海岭和Knipovich海岭）与Bear岛区的大陆边缘动力学”

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海洋地质 2008年第3期24卷 52-53页

作者： Johannes Schweitzer Aleksander Guterch Frank Kruger Meehita schmidt- Aursch Rolf Mjelde Marek Grad jan Inge Faleide 孙桂华（译）邱燕（校对）挪威地震研究中心波兰科学院德国波茨坦大学德国阿尔弗雷德·魏格纳研究所挪威卑尔根大学波兰华沙大学挪威奥斯陆大学不详

2007年，我们发起了一个主动地震和被动地震的地震学实验，实验地点是Bear岛附近的巴伦支海大陆边缘、Mohns海岭和Knipovich海岭之间的结合部和大西洋东北部的扩张轴。2007～2008年间的野外实验主要是安装几台地震仪器，实施相关的野外... 详细信息

2007年，我们发起了一个主动地震和被动地震的地震学实验，实验地点是Bear岛附近的巴伦支海大陆边缘、Mohns海岭和Knipovich海岭之间的结合部和大西洋东北部的扩张轴。2007～2008年间的野外实验主要是安装几台地震仪器，实施相关的野外操作。这项研究的目标是大陆边缘沉积盖层至上地幔的地球结构和动力学机制，因为该大陆边缘包含一个非常厚的沉积楔和至少一个古断裂带。

关键词：大西洋中部动力学机制大陆边缘海岭野外实验沉积盖层被动地震巴伦支海

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作为合同自由界限的环境保护

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中国应用法学 2019年第1期 81-94页

作者： [德]扬·李德菲利普·波兹克周心童(译) 弗莱堡阿尔伯特-路德维希大学经济法劳动与社会法研究所经济法分部弗莱堡阿尔伯特-路德维希大学经济法劳动与社会法研究所

伴随着《中华人民共和国民法总则》第9条,一项环境保护义务被纳入了中国民法。今后当法律主体从事法律行为时,必须有利于节约资源和保护生态环境。本文涉及到第9条会在何种程度上限制由民法总则第5条所保障的合同自由。为此目的,本文将... 详细信息

伴随着《中华人民共和国民法总则》第9条,一项环境保护义务被纳入了中国民法。今后当法律主体从事法律行为时,必须有利于节约资源和保护生态环境。本文涉及到第9条会在何种程度上限制由民法总则第5条所保障的合同自由。为此目的,本文将借由德国法上可资比较之规定就本规定之内容和范围进行一项批判性与建设性兼备的分析。

关键词：绿色原则环境保护合同自由自愿原则

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GRADE指南：Ⅶ.证据质量评价--不一致性

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中国循证医学杂志 2011年第12期11卷 1444-1451页

作者： Gordon H.Guyatt Andrew D.Oxman Regina Kunz James Woodcock jan Brozek Mark Helfand Pablo Alonso-Coello Paul Glasziou Roman Jaeschke Elie A.Akl Susan Norris Gunn Vist philipp Dahm Vijay K.Shukla Julian Higgins Yngve Falck-Ytter Holger J.Schünemann 代表GRADE小组李幼平杨晓妍王莉蔡羽嘉陈群飞机构不详

本文针对二分类变量结局指标相对(而非绝对)治疗效果的不一致性。证据本身不会因不同研究结果具有一致性而升级,但可能因不一致而降低质量级别。衡量一致性的标准包括点估计值的相似性、可信区间的重叠程度以及统计学判定标准包括异质... 详细信息

本文针对二分类变量结局指标相对(而非绝对)治疗效果的不一致性。证据本身不会因不同研究结果具有一致性而升级,但可能因不一致而降低质量级别。衡量一致性的标准包括点估计值的相似性、可信区间的重叠程度以及统计学判定标准包括异质性检验和I2。系统评价作者应提出并检验少数几个与患者、干预措施、结局指标以及方法学相关的先验假设以探寻异质性来源。当不一致性很大且无法解释时,因不一致性而降低质量级别是恰当的,特别当某些研究显示有显著益处而其他显示无益甚至有害时(而非仅是疗效大与疗效小的比较)。明显的亚组效应可能不可靠。如果亚组效应满足以下条件,其可信度将会增加:基于少数几个有具体方向的先验假设、亚组比较来自研究内而非研究间、交互检验的P值小、结果有生物学意义。

关键词： GRADE 不一致性异质性变异性亚组分析交互作用

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GRADE指南：Ⅸ.证据质量升级

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中国循证医学杂志 2011年第12期11卷 1459-1463页

作者： Gordon H.Guyatt Andrew D.Oxman Shahnaz Sultan Paul Glasziou Elie A.Akl Pablo Alonso-Coello David Atkins Regina Kunz jan Brozek Victor Montori Roman Jaeschke David Rind philipp Dahm Joerg Meerpohl Gunn Vist Elise Berliner Susan Norris Yngve Falck-Ytter M.Hassan Murad Holger J.Schünemann 代表GRADE工作组李幼平杨晓妍李玲王应强机构不详

证据质量升级的最常见原因是效应量大。当方法学严谨的观察性研究表明风险至少降低或增加2倍时,GRADE建议考虑将证据质量升高1级;当风险至少降低或增加5倍时,考虑将证据质量升高2级。当存在剂量-反应关系,或所有合理的混杂、偏倚会降低... 详细信息

证据质量升级的最常见原因是效应量大。当方法学严谨的观察性研究表明风险至少降低或增加2倍时,GRADE建议考虑将证据质量升高1级;当风险至少降低或增加5倍时,考虑将证据质量升高2级。当存在剂量-反应关系,或所有合理的混杂、偏倚会降低明显的治疗效应,或混杂、偏倚使得结果无效为假效应时,系统评价作者和指南制定者也可考虑升高证据质量。其他考虑因素包括起效迅速、潜在的疾病(状态)趋势以及间接证据。

关键词： GRADE 指南证据等级观察性研究效应量大偏倚风险

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