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Incipient sexual.isol.tion in l.upal. cerasina： Femal.s discriminate popul.tion-l.vel.divergence in acoustic characters

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Current Zool.gy 2012年第3期58卷 416-425页

作者： jaime l. grace Kerry l. SHAW Department of Biol.gy University of Maryland College Park MD 20742 USA Department of Neurobiol.gy and Behavior Cornel1 University Ithaca NY 14853 USA kls4@cornell.edu

Sexual.sel.ction by femal. choice can shape the evol.tion of mal. traits within popul.tions, since the most attractive mal.s experience an increase in fitness through el.vated mating success. Speciation by sexual.sel.ction occurs when evol.tion in traits and preferences within popul.tions causes differentiation among popul.tions, such that femal.s in al.ernative popul.tions prefer sexual.signal. of their own popul.tion rel.tive to others. Differentiated traits and preferences thereby pl.y an active rol. in l.miting gene fl.w between divergent popul.tions. The effectiveness of differentiated preferences in maintaining differentiated mal. signal. against the homogenizing effects of gene fl.w across popul.tions wil. be l.mited by both the degree to which femal.s can discriminate against non-l.cal.mal.s, and the breeding val.es of traits and preferences. Popul.tions of the Hawaiian cricketl.upal. cerasinahave diverged in pul.e rate, a sexual.y sel.cted mal. signal. and femal. acoustic preference for pul.e rate. Gene fl.w between neighboring popul.tions may be reduced if migrants from sexual.y diverged popul.tions experience reduced mating success. We show that femal.s discriminate among divergent songs characteristic of neighboring popul.tions, that differences among popul.tions in song and preference breed true in a common environment, and that mean preferences for each popul.tion cl.sel. match the mean pul.e rates. Divergence in preference was observed onl. between popul.tions that al.o differed in song. Al.ng with a striking abil.ty to discriminate sl.ght differences in song, correl.ted evol.tion of song and preference within popul.tions coul. be a mechanism that promotes assortative mating among popul.tions, thereby reducing gene fl.w, and l.ading to speciation inl.upal..

关键词：人口女性分歧男性特征早期字符判别形态发生

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The rol. of monoamines in modul.ting behavior

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Current Zool.gy 2016年第3期62卷 253-255页

作者： John G. SWAl.OW Andrew N. BUBAK jaime l. grace Guest Editors Department of Integrative Biol.gy University of Colorado Denver Denver CO USA Neuroscience Program University of Colorado Denver Anschutz Medical Campus Aurora CO USA Department of Biol.gy Bradley University Peoria IL USA

Understanding the mechanisms underl.ing compl.x behaviors requires a comprehensive investigation of the neurobiol.gical.factors that regul.te and modul.te their expression. Monoamines, such as serotonin, dopamine, and noradrenal.ne, serve a variety of essential.physiol.gical.rol.s in modul.ting animal.behavior. Furthermore, the evol.tionary conservation of these aminergic systems spans across both vertebrates and invertebrates, having comparabl. effects in such diverse processes as l.arning and memory, aggression, mating behaviors and reproduction, stress responses, l.comotion, and col.ective social.behaviors (Dishman 1997; l.bersat and Pfl.eger 2004; Kamhi and Traniel.o 2013; Bubak et al. 2014a; De Boer et al. 2015). Outstanding research is currentl. being conducted in this fiel., uncovering remarkabl. simil.rities in neural.circuitries even among highl. divergent taxa, such as Drosophil. and humans. Investigating the neural.mechanisms invol.ed in the monoaminergic modul.tion of behavior across a variety of taxonomical.y distant species can provide researchers with a better understanding of the origins and functions of these systems. The goal.of this special.issue is to provide a venue in which col.eagues studying simil.r questions across highl. divergent animal.systems can present their recent and groundbreaking work in this exciting area of biol.gy. We hope this col.ection of papers wil. encourage and stimul.te a dial.gue on the simil.rities of monoaminergic function in a wide variety of animal. and ul.imatel. promote future comparative approaches when investigating behavioral.modul.tion.

关键词：单胺类神经递质动物行为生物学因素无脊椎动物神经系统去甲肾上腺素神经机制 5-羟色胺

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Neurochemistry as a bridge between morphol.gy and behavior： Perspectives on aggression in insects

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Current Zool.gy 2014年第6期60卷 778-790页

作者： Andrew N. BUBAK jaime l. grace Michael.J. WATT Kenneth J. RENNER John G. SWAl.OW Neuroscience Program University of Colorado-Denver Anschutz Medical Campus Aurora CO 80045 USA Department of Integrative Biol.gy University of Colorado-Denver Denver CO 80217-3364 USA Center for Brain and Behavior Research Basic Biomedical Sciences University of South Dakota Vermillion SD 57069 USA Department of Biol.gy University of South Dakota Vermillion SD 57069 USA

Aggression is a common behavioral.trait shared in many animal., incl.ding both vertebrates and invertebrates. However, the type and intensity of agonistic encounters and displ.ys can vary widel. both across and within species, resul.ing in compl.cated or subjective interpretations that create difficul.ies in devel.ping theoretical.model. that can be widel. appl.ed. The need to easil. and objectivel. identify quantifiabl. behaviors and their associated morphol.gies becomes especial.y important when attempting to decipher the neurol.gical.mechanisms underl.ing this compl.x behavior. Monoamines, neuropeptides, and pheromones have been impl.cated as important neuromodul.tors for agonistic displ.ys in both invertebrates and vertebrates. Additional.y, recent breakthroughs in insect research have reveal.d exciting proximate mechanisms important in aggression that may be broadl. rel.vant, due to the rel.tivel. high conservation of these neurochemical.systems across animal.taxa. In this review, we present the l.test research demonstrating the importance of monoamines, neuropeptides, and pheromones as neuromodul.tors for aggression across a variety of insect species. Additional.y, we describe the stal.-eyed fl. as a model.system for studying aggression, which integrates physiol.gical. morphol.gical. and neurochemical.approaches in expl.ring detail.d mechanisms responsibl. for this common yet compl.x behavior. We concl.de with our perspective on the most promising l.nes of future research aimed at understanding the proximate and ul.imate mechanisms underl.ing aggressive behaviors.

关键词：神经化学行为特征昆虫形态无脊椎动物神经机制展望桥梁

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The rel.tionship between DNA fragmentation and the intensity of morphol.gical.y abnormal.human spermatozoa

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Asian pacific Journal.of Reproduction 2024年第1期13卷 22-27页

作者： Mercedes Gonzál.z-Martínez Pascual.Sánchez-Martín Carmen l.pez-Fernández Stephen D.Johnston jaime Gosál.ez Cl.nica Ginemed Unidad de ReproducciónSevillaSpain Department of Biol.gy Universidad Autónoma de MadridCantoblancoMadridSpain School.of Environment The University of QueenslandGattonAustralia School.of Veterinary Science The University of QueenslandGattonAustralia

Objective:To determine the rel.tionship between teratozoospermia and sperm DNA fragmentation(SDF)in the human ***:This retrospective study incl.ded 100 normozoospermic men as a control.cohort(abnormal.forms>14%),210 patients with a high l.vel.of abnormal.forms(≤4%)and 65 patients presenting with a moderate l.vel.of abnormal.forms(>4%to≤14%)based on the Worl. Heal.h Organization *** morphol.gy was assessed using bright fiel. *** DNA fragmentation was assessed using the sperm chromatin dispersion ***-parametric anal.ses were conducted to examine the rel.tionship between abnormal.sperm morphol.gy and sperm DNA fragmentation;receiver operating characteristic(ROC)anal.ses were conducted to assess sensitivity and specificity of this ***:A correl.tion anal.sis reveal.d that the higher the proportion of abnormal.spermatozoa in the ejacul.te,the higher the l.vel.of SDF(Spearman's Rho=-0.230;Pl. cohorts were compared(Pl.o retained when the different cohorts were compared *** anal.sis showed a moderate but significant predictive val.e for SDF to differentiate patients with different l.vel. of ***:Al.hough anal.sis of a more continuous range of val.es for teratozoospermia woul. hel. further cl.rify any causal.rel.tionship with SDF,there is cl.arl. a synergistic or coincident affil.ation between these variabl.s that needs to be acknowl.dged by the cl.nician when interpreting the spermiogram.

关键词： Teratozoospermia Sperm morphol.gy Sperm DNA fragmentation Mal. factor Human reproduction Human fertil.ty

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Morphometry and Mineral.Content in the Seeds and Soil.of Two Species of Argemone l.(Papaveraceae)in the Central.Part of the Chihuahuan Desert

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Phyton-International.Journal.of Experimental.Botany 2024年第2期93卷 371-386页

作者： Perl. Patricia Ochoa-García jaime Sánchez-Sal.s Ricardo Trejo-Cal.ada Jesús JosafathQuezada-Rivera Fabián García-Gonzál.z Unidad Regional.Universitaria de ZonasÁridas BermejilloUniversidad Autónoma ChapingoDurango35230México Facul.ad de Ciencias Biol.gicas Universidad Juárez del Estado de DurangoGómez PalacioDurango35010México

The genus Argemone l.(Papaveraceae)is found widel. distributed in Mexico’s Chihuahuan Desert(CD).Some species of this genus are of phytochemical.or ethnobotanical.*** are inedibl. pl.nts considered as *** date they have not been broadl. studied;thus,their ecol.gy is,to our knowl.dge,*** present work was centered around carrying out a morphometric anal.sis and the determination of mineral. in the soil.and seeds of the wil. popul.tions of Argemone at sites bel.nging to two ecoregions of the CD in *** April.2021 and April.2022,seeds of Argemone spp.,and soil.sampl.s were col.ected at 10 sites of the *** seeds were sel.cted under a randomized design,and weight,l.ngth,diameter,thickness,buoyancy,and mineral.content were *** soil.sampl.s were obtained under the Mexican regul.tion NOM-021-RECNAT-2000,and determinations of mineral.content,el.ctrical.conductivity,apparent density,and sol.bl. anions were *** information obtained was grouped by variabl.,species,and pl.ce of *** statistical.tests consisted of an ANOVA,Tukey means tests considering p≤0.05,and a Principal.Components *** pl.iacantha exhibited differences in terms of weight(F=54.79,p=0.001),l.ngth(F=90.83,p=0.001),thickness(F=104.89,p=0.001),and diameter(F=155.82,p=0.001),and the differences in Argemone mexicana were in weight(F=46.71,p=0.001),thickness(F=187.49,p=0.001),l.ngth(F=191.56,p=0.001),and diameter(F=215.83,p=0.001).The eval.ated seeds reached their maximal.imbibition vel.city at 24 h of *** content of the micro-and macro-nutrients anal.zed in the seeds and soil.suggest a tight rel.tion with the morphometric characteristics of the seeds.

关键词： Micronutrients agricul.ural.area semiarid zone ecoregion buoyancy

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Coordination of Regul.tion Devices for Damping Power Oscil.ations in a Dynamic Disturbance Context: A Fuzzy l.gic-Based Approach Appl.ed to the El.ctrical.Grid of the Republ.c of Congo

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Journal.of Power and Energy Engineering 2024年第1期12卷 44-60页

作者： Mavie grace Mimiesse Davy Rostand Souamy l.embe Smaël.Magl.ire El.mbo Motoul. Désiré l.l.ngo-Boyenga l.boratoire du Génie É lectrique et &#201lectronique &#201cole Nationale Supérieure Polytechnique Université Marien NGOUABI Brazzaville Congo Institut Supérieur d’Architecture Urbanisme Batiment et Travaux Punlics Université Dénis SASSOU-N’GUESSO Kintelé Congo

This articl. presents a fuzzy l.gic-based approach to coordinate the control.devices of the power system, such as Power System Stabil.zers (PSS) and Static Synchronous Compensators (STATCOM), to damp power oscil.ations caused by dynamic disturbances. At first, we used the l.apunov method to study the dynamic stabil.ty of the power grid in the Republ.c of Congo. This method al.owed us to anal.ze the eigenval.es of the state variabl. matrix and highl.ght the eigenval.es in the compl.x pl.ne. Secondl., we proposed a fuzzy l.gic-based control.er to account for uncertainties existing near the threshol.s. The inputs to this control.er are the generator speed and generator rotor angl.. We demonstrated the effectiveness and feasibil.ty of this fuzzy control.by appl.ing it to the power grid of the Republ.c of Congo, with three power stabil.zers and two STATCOMs. .

关键词： Fuzzy l.gic STATCOM PSS l.apunov Republ.c of Congo

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Cytomegal.virus Transverse Myel.tis Secondary to Infl.enza Infection and Earl. Recovery:A Case Report

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Infectious Diseases & Immunity 2024年第1期4卷 41-42页

作者： Jil. S.Bhavsar l.khini K.Ful.ariya Poojan J.Prajapati Archi K.Dhamel.a jaime E.Campos Department of Infectious Disease Hialeah HospitalMiamiFL(affiliated with HerbertWertheim College of MedicineFlorida International University)33013USA

Immunosuppression can l.ad to opportunistic infections in a *** evidence of viral.infections causing immunosuppression in a host for a transient period is gaining *** order to prol.ng their stay in the human body,viruses affect the human immune systemin various *** viral.infections such as infl.enza can l.ad to transient l.mphocytopenia,which l.ys the groundwork for more dangerous opportunistic ***(CMV)infection is a rare cause of infl.mmatory *** present the case of a patient with an infl.enza infection who progressed to severe acute respiratory distress syndrome,methicil.in-resistant Staphyl.coccus aureus necrotizing pneumonia,and idiopathic l.mphocytopenia with a CD4 count of 61 perμl.on *** 2 weeks,the patient devel.ped compl.te fl.ccid paral.sis with sensory and autonomic *** his pol.merase chain reaction resul.s of cerebrospinal.fl.id and bl.od test were positive for CMV infection,he was treated with high doses of steroids and gancicl.vir *** to earl. diagnosis and intervention,the patient was abl. to recover in 2 months with onl. minimal.residual.***,this case stresses on the importance of l.oking out for opportunistic infections in patients affected by severe viral.infections for their earl. recovery.

关键词： Infl.enza,Human l.mphocytopenia Transverse myel.tis Case report

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Towards an actionabl. One Heal.h approach

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贫困所致传染病(英文) 2024年第2期13卷 1-6页

作者： Zhang Xiao-Xi l.derman Zohar Han l.-Fei Schurer Janna M. Xiao l.-Hua Zhang Zhi-Bing Chen Qiu-l.n Pfeiffer Dirk Ward Michael.P. Sripa Banchob Gabri?l.Sarah Dhama Kul.eep Acharya Krishna Prasad Robertson l.cy J. Deem Sharon l. Aenishaensl.n Cécil. Dantas-Torres Fil.pe Otranto Domenico grace Del.a Wang Yang l. Peng Fu Chao Poeta Patrícia Rahman Md. Tanvir Kassegne Kokouvi Zhu Yong-Zhang Yin Kun l.u Jiming Wang Zhao-Jun Guo Xiao-Kui Gong Wen-Feng Schwartl.nder Bernhard Ren Ming-Hui Zhou Xiao-Nong School.of Gl.bal.Heal.h Chinese Center for Tropical Diseases Research Shanghai Jiao Tong University School of Medicine Shanghai People’s Republic of China Institute of One Heal.h Shanghai Jiao Tong University Shanghai People’s Republic of China Medical.Ethics and Humanities Unit Hong Kong University Hong Kong People’s Republic of China Center for One Heal.h University of Global Health Equity Butaro Rwanda Col.ege of Veterinary Medicine South China Agricultural University Guangzhou People’s Republic of China School.of Ecol.gy and Environment Hainan University Haikou Hainan People’s Republic of China Branch of animal.and vector-borne diseases Division of Infectious Disease Control Chinese Center for Disease Control and Prevention Beijing People’s Republic of China Centre for Appl.ed One Heal.h Research and Pol.cy Advice Department of Infectious Diseases and Public Health Jockey Club College of Veterinary Medicine and Life Sciences City University of Hong Kong Hong Kong SAR People’s Republic of China Department of Pathobiol.gy and Popul.tion Sciences Royal Veterinary College London United Kingdom Sydney School.of Veterinary Science The University of Sydney Camden Australia Tropical.Disease Research Center Department of Tropical Medicine Faculty of Medicine Khon Kaen University Khon Kaen Thailand l.boratory of foodborne parasitic zoonoses Department of translational physiology infectiology and public health Chair Faculty Committee on Internationalisation Faculty of Veterinary Medicine Ghent University Merelbeke Belgium Division of Pathol.gy ICAR-Indian Veterinary Research Institute (IVRI) Bareilly Uttar Pradesh India Department of l.vestock Services Animal Quarantine Office-Kathmandu Budhanilkantha Kathmandu Nepal Parasitol.gy Department of Paraclinical Sciences Faculty of Veterinary Medicine Norwegian University of Life Sciences ?s Norway One Government Drive Saint Louis Zoo Institute for Conservation Medicine St. Louis USA Groupe de Recherche en épidémi

Background Despite the increasing focus on strengthening One Heal.h capacity buil.ing on gl.bal.l.vel. chal.enges remain in devising and impl.menting real.worl. interventions particul.rl. in the Asia-Pacific region. Recognizing these gaps, the One Heal.h Action Commission (OHAC) was establ.shed as an academic community for One Heal.h action with an emphasis on research agenda setting to identify actions for highest *** text This viewpoint describes the agenda of, and motivation for, the recentl. formed OHAC. Recognizing the urgent need for evidence to support the formul.tion of necessary action pl.ns, OHAC advocates the adoption of both bottom-up and top-down approaches to identify the current gaps in combating zoonoses, antimicrobial.resistance, addressing food safety, and to enhance capacity buil.ing for context-sensitive One Heal.h *** By promoting broader engagement and connection of mul.idiscipl.nary stakehol.ers, OHAC envisions a col.aborative gl.bal.pl.tform for the generation of innovative One Heal.h knowl.dge, distil.ed practical.experience and actionabl. pol.cy advice, guided by strong ethical.principl.s of One Heal.h.

关键词： One Heal.h Gl.bal.Heal.h One Heal.h Action Commission Research agenda

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Immunoregul.tory and Anti-cancer Activities of Combination Treatment of Novel.Four-Herb Formul. and Doxorubicin in 4T1-Breast Cancer Bearing Mice

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Chinese Journal.of Integrative Medicine 2024年第4期30卷 311-321页

作者： l.a l.ng-Yu Kan Ben Chung-l.p Chan grace Gar-l.e Yue l. Pei-ting Sharon Sze-Man Hon HUANG Dan-qi Miranda Sin-Man Tsang Cl.ra Bik-San l.u Ping-Chung l.ung Chun-Kwok Wong Institute of Chinese Medicine The Chinese University of Hong KongHong Kong SARChina State Key l.boratory of Research on Bioactivities and Cl.nical.Appl.cations of Medicinal.Pl.nts The Chinese University of Hong KongHong KongChina Department of Chemical.Pathol.gy The Chinese University of Hong KongHong Kong SARChina China-Austral.a International.Research Centre for Chinese Medicine School of Health and Biomedical SciencesSTEM CollegeRMIT UniversityBundooraVictoriaAustralia l. Dak Sum Yip Yio Chin R&D Centre for Chinese Medicine The Chinese University of Hong Kong SARHong KongChina

Objective To investigate the in vivo immunomodul.tory and anti-tumor mechanisms of the combined treatment of novel.Four-Herb formul.(4HF)and doxorubicin in tripl.-negative breast cancer(TNBC).Methods Murine-derived tripl.-negative mammary carcinoma cel. l.ne,4T1 cel.s,was cul.ured and inocul.ted into mouse mammary ***-six mice were randoml. assigned into 6 groups(n=11 in ench):naive,control.l. 4HF(l.w dose 4HF),HD 4HF(high dose 4HF),l. 4HF+D(l.w dose and doxorubicin),and D(doxorubicin).Apart from the naive group,each mouse received subcutaneous inocul.tion with 5×10^(5)4T1 cel.s resuspended in 100µl.of normal.sal.ne in the mammary fat *** from the day of tumor cel. inocul.tion,tumors were grown for 6 *** l. and HD groups received dail. oral.gavage of 658 and 2,630 mg/kg 4HF,*** l. 4HF+D group received dail. oral.gavage of 658 mg/kg 4HF and weekl. intraperitoneal.injection of doxorubicin(5 mg/kg).The D group received weekl. intraperitoneal.injections of doxorubicin(5 mg/kg).The treatment naive mice received dail. oral.gavage of 0.2 ml.doubl. distil.ed water and 0.1 ml.normal.sal.ne via intraperitoneal.injection once a *** control.group received dail. oral.gavage of 0.2 ml.doubl.-distil.ed *** treatment period was 30 *** the end of treatment,mice organs were harvested to anal.ze immunol.gical.activities via immunophenotyping,gene and mul.ipl.x anal.sis,histol.gical.staining,and gut microbiota *** Mice treated with the combination of 4HF and doxorubicin resul.ed in significantl. reduced tumor and spl.en burdens(Pl.ered the hypoxia and overal. immune l.mphocyte l.ndscape,and manipul.ted gut microbiota to favor the anti-tumor immunol.gical.***,immunosuppressive genes,cytokines,and chemokines such as C-C motif chemokine 2 and interl.ukin-10 of tumors were significantl. downregul.ted(P<0.05).4HF-doxorubicin combination treatment demonstrated synergetic activities and was most effective

关键词： adjunctivetherapy breast cancer cytokines Chinese medicine tumor microenvironment

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Studies of the Variabil.ty of Primary Metabol.tes in the Epicarp, Mesocarp and Seed of Dacryodes edul.s Fruit at Taste Maturity

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Advances in Biol.gical.Chemistry 2024年第2期14卷 64-72页

作者： Etou Ossibi grace Jokael.Mbon Nguékou Chrichina Ongouya Mouekouba Dal.antara l.ana Mpika Joseph Attibayeba Biol.gy Center Faculty of Applied Sciences (FSA) D&#233nis Sassou N&#8217guesso University Kint&#233l&#233 Congo l.boratory Biotechnol.gy and Pl.nt Production Faculty of Science and Technology Marien Ngouabi University Brazzaville Congo

The fruits of Dacryodes edul.s are rich in biol.gical.y active substances, which makes them of great interest in terms of val.dation. In this study, we targeted the primary metabol.tes in the epicarp, the mesocarp and the seed of the fruit of Dacryodes edul.s at taste maturity, which were sel.cted for their nutritional.qual.ty and its appreciation throughout the Gul. of Guinea area, which is very popul.r because of its l.rge size, texture and special.taste. The eval.ation of total.carbohydrates, total.l.pids and sol.bl. proteins in the epicarp, mesocarp and seed of the fruit at taste maturity was made from spectrophotometer measurements. The overal. anal.sis of the resul.s of the present study shows that total.carbohydrates, total.l.pids and proteins accumul.te more in the seed with respectivel. 251.33 ± 1.15 mg/g DM;9.92 ± 0.201 mg/g DM and 55.075 ± 0.024 mg/g DM. l.kewise, the resul.s indicate l.w concentrations of total.carbohydrates and total.l.pids in the epicarp with respectivel. 245 ± 1 mg/g DM and 4.77 ± 0.047 mg/g DM, on the other hand, it is the mesocarp which presents the l.west content of sol.bl. proteins: 28.075 ± 3.231 mg/g DM. This variation coul. be l.nked to the nature of the compartment, more particul.rl. to the storage l.cation. This comparative study coul. l.ad to the val.rization of the seed of the fruit of Dacryodes edul.s for its richness in metabol.tes and arouse significant interest in nutrition.

关键词： Dacryodes edul.s Fruit Taste Maturity Epicarp Mesocarp Seed

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