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垃圾焚烧飞灰水泥固化体的抗压强度和浸出性研究

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环境工程学报 2016年第6期10卷 3207-3214页

作者：尚宁王海洋吴华南 ko jae Hac 徐期勇北京大学深圳研究生院环境与能源学院深圳聚硅酸盐复合环保材料工程实验室深圳518055

利用垃圾焚烧飞灰掺入普通硅酸盐水泥制备水泥固化体,通过浸出性实验,研究了飞灰掺量(0%、20%、40%与60%)、浸出液pH及水洗预处理对水泥固化体抗压强度及重金属(Zn、Pb、Cu、Cd、Cr、Ni)浸出的影响。结果表明:对于非水洗飞灰水泥固化体... 详细信息

利用垃圾焚烧飞灰掺入普通硅酸盐水泥制备水泥固化体,通过浸出性实验,研究了飞灰掺量(0%、20%、40%与60%)、浸出液pH及水洗预处理对水泥固化体抗压强度及重金属(Zn、Pb、Cu、Cd、Cr、Ni)浸出的影响。结果表明:对于非水洗飞灰水泥固化体,pH为4.2和10.0下浸出84 d时,相同组成固化体抗压强度较为接近,飞灰掺量20%,40%和60%的固化体抗压强度分别为41、15和10 MPa左右;除掺量为40%和60%的固化体浸出液中重金属(pH为4.2时Ni和Pb,pH为10.0时Ni)超出生活饮用水卫生标准(GB 5749-2006)外,掺量为40%和60%的固化体的其余浸出液及掺量20%的固化体浸出液中测定的重金属浓度均符合生活饮用水卫生标准。对于水洗飞灰水泥固化体,pH为4.2和10.0下浸出84 d时,相同组成固化体抗压强度较为接近,飞灰掺量20%、40%和60%的固化体抗压强度分别为37、32和10 MPa左右;除掺量为60%的固化体浸出液(pH为4.2和10.0)中Ni和Pb均超出生活饮用水卫生标准外,掺量为60%的固化体的其余浸出液及飞灰掺量20%和40%的固化体浸出液中测定的重金属浓度均符合生活饮用水卫生标准。飞灰水洗预处理提高了飞灰掺量40%水泥固化体抗压强度,同时降低了重金属浸出性。

关键词：垃圾焚烧飞灰水洗预处理 pH 长期浸出性抗压强度

Development of a hybrid scaffold and a bioreactor for cartilage regeneration

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Chinese Science Bulletin 2009年第19期54卷 3608-3612页

作者： LEE Seung-jae LEE In Hwan PARK Jeong Hun GWAK So-Jung RHIE Jong-Won CHO Dong-Woo ko Tae Jo KIM Dong Sung BK21 Mechatronics Group at Chungnam National University School of Mechanical Engineering Chungbuk National University DDS Research Lab. CKD Research Institute CKD Pharmaceutical Corp. Department of Plastic Surgery College of Medicine The Catholic University of Korea Department of Mechanical Engineering Pohang University of Science and Technology School of Mechanical Engineering Yeungnam University School of Mechanical Engineering Chung-Ang University

We developed a hybrid scaffold and a bioreactor for cartilage regeneration. The hybrid scaffold was developed as combination of two components: a biodegradable framework and hydrogel-containing chondrocytes. We performed the MTT cell proliferation assay to compare the proliferation and viability of chondrocytes on three types of scaffolds: an alginate gel, the hybrid scaffold, and an alginate sponge. Cells were encapsulated in 2% agarose gel. The bioreactor consisted of a circulation system and a compression system. We performed dynamic cell culture on these agarose gels in the bioreactor for 3 days.

关键词： MTT 生物分解凝解胶研究

模拟生活垃圾填埋反应器堆体底部抽气对污染气体排放的控制

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环境工程学报 2020年第11期14卷 3182-3191页

作者：杜越 ko jae Hac 黄丹丹王前向静雅徐期勇北京大学深圳研究生院环境与能源学院深圳518055 济州国立大学海洋科学学院济州岛63243韩国

在填埋作业期间,生活垃圾填埋场由于缺少覆盖材料和集气系统,导致填埋气排放缺乏有效控制。为探究垃圾堆体抽气操作对填埋气的减排作用,搭建了3个模拟反应器,包括不抽气的对照组(C)、低抽气量组(E1)和高抽气量组(E2)。在为期171 d的实验... 详细信息

在填埋作业期间,生活垃圾填埋场由于缺少覆盖材料和集气系统,导致填埋气排放缺乏有效控制。为探究垃圾堆体抽气操作对填埋气的减排作用,搭建了3个模拟反应器,包括不抽气的对照组(C)、低抽气量组(E1)和高抽气量组(E2)。在为期171 d的实验中,垃圾分3层填埋,使用静态通量箱法,探究了3个反应器中二氧化碳、甲烷及含硫恶臭气体(甲硫醇、二硫化碳、甲硫醚、乙硫醚和二甲二硫醚)排放通量随反应器运行时间和垃圾堆体抽气操作强度的变化情况。结果表明:E2组比C组更早产生甲烷,但其抽气后减排率可达100%;而E1一直未检测到甲烷,可能是因为甲烷化过程并未建立,或是其中甲烷被覆土中的甲烷氧化菌氧化。此外,与自身抽气前相比,E1和E2对5种硫化物具有不同程度的减排效果,但E2的效果更好。上述研究结果可为填埋场的温室气体和含硫恶臭气体减排策略的制定提供参考。

关键词：生活垃圾填埋场抽气气体排放控制温室气体含硫气体

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填埋垃圾渗透系数的研究进展

环境工程 2014年第8期32卷 80-84,88页

作者：李明英 jae Hac ko 徐期勇北京大学深圳研究生院环境与能源学院聚硅酸盐复合环保材料工程实验室广东深圳518055

填埋是我国城市生活垃圾的主要处理方式,我国南方填埋场普遍面临的一个问题是渗滤液水位较高。垃圾渗透系数不仅在控制渗滤液水位技术方面有重要作用,且影响填埋气的排出及回收利用率。总结了垃圾渗透系数影响因素和调节方法方面的研究... 详细信息

填埋是我国城市生活垃圾的主要处理方式,我国南方填埋场普遍面临的一个问题是渗滤液水位较高。垃圾渗透系数不仅在控制渗滤液水位技术方面有重要作用,且影响填埋气的排出及回收利用率。总结了垃圾渗透系数影响因素和调节方法方面的研究,得出影响因素包括垃圾密度、垃圾组分、降解程度、压实程度等,调节方法则有改变影响因素和加入惰性材料两种。在此基础上对填埋场控制渗滤液水位的工程技术手段和提高填埋体回收利用率的途径提出了新建议。

关键词：垃圾填埋场渗透系数影响因素

Vitisin B inhibits influenza A virus replication by multi-targeting neuraminidase and virusinduced oxidative stress

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Acta Pharmaceutica Sinica B 2023年第1期13卷 174-191页

作者： Eun-Bin Kwon Wei Li Young Soo Kim Buyun Kim Hwan-Suck Chung Younghoon Go Hyun-Jeong ko jae-Hyoung Song Young Ho Kim Chun Whan Choi Jang-Gi Choi korean Medicine(KM)Application Center Korea Institute of Oriental MedicineDaegu 41062Republic of Korea College of Pharmacy Chungnam National UniversityDaejeon 34134Republic of Korea Natural Product Research Team BiocenterGyeonggido Business and Science AcceleratorGyeonggi-Do 16229Republic of Korea Laboratory of Microbiology and Immunology College of PharmacyKangwon National UniversityChuncheon 24341Republic of Korea

The development of drug-resistant influenza and new pathogenic virus strains underscores the need for antiviral ***,neuraminidase(NA)inhibitors are commonly used antiviral drugs approved by the US Food and Drug Administration(FDA)for the prevention and treatment of ***,we show that vitisin B(VB)inhibits NA activity and suppresses H1N1 viral replication in MDCK and A549 *** oxygen species(ROS),which frequently occur during viral infection,increase virus replication by activating the NF-κB signaling pathway,downmodulating glucose-6-phosphate dehydrogenase(G6PD)expression,and decreasing the expression of nuclear factor erythroid2-related factor 2(Nrf2)antioxidant response *** decreased virus-induced ROS generation by increasing G6PD expression and Nrf2 activity,and inhibiting NF-κB translocation to the nucleus through IKK *** addition,VB reduced body weight loss,increased survival,decreased viral replication and the inflammatory response in the lungs of influenza A virus(IAV)-infected *** together,our results indicate that VB is a promising therapeutic candidate against IAV infection,complements existing drug limitations targeting viral *** modulated the intracellular ROS by G6PD,Nrf2 antioxidant response pathway,and NF-κB signaling *** results demonstrate the feasibility of a multi-targeting drug strategy,providing new approaches for drug discovery against IAV infection.

关键词： Influenza Vitisin B Vitis vinifera L. Neuraminidase Reactive oxygen species NF-κB Multi-targeting Nrf2 G6PD

Plant ABC Transporters Enable Many Unique Aspects of a Terrestrial Plant＇s Lifestyle

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Molecular Plant 2016年第3期9卷 338-355页

作者： jae-Ung Hwang Won-Yong Song Daewoong Hong Donghwi ko Yasuyo Yamaoka Sunghoon Jang Sojeong Yim Eunjung Lee Deepa Khare Kyungyoon Kim Michael Palmgren Hwan Su Yoon Enrico Martinoia Youngsook Lee Department of Life Science Pohang University of Science and Technology (POSTECH) Pohang 37673 Korea Division of Integrative Bioscience and Biotechnology POSTECH Pohang 37673 Korea Center for Membrane Pumps in Cells and Disease - PUMPKIN Danish National Research Foundation Department of Plant and Environmental Science University of Copenhagen 1871 Frederiksberg Denmark Department of Biological Sciences Sungkyunkwan University Suwon 16419 Korea Department of Plant and Microbial Biology University Zurich Zurich 8008 Zurich Switzerland

Terrestrial plants have two to four times more ATP-binding cassette （ABC） transporter genes than other organisms, including their ancestral microalgae. Recent studies found that plants harboring mutations in these transporters exhibit dramatic phenotypes, many of which are related to developmental processes and functions necessary for life on dry land. These results suggest that ABC transporters multiplied during evolution and assumed novel functions that allowed plants to adapt to terrestrial environmental conditions. Examining the literature on plant ABC transporters from this viewpoint led us to propose that diverse ABC transporters enabled many unique and essential aspects of a terrestrial plant＇s lifestyle, by transporting various compounds across specific membranes of the plant.

关键词： abscisic acid transporter adaptation to dry (and ATP-binding cassette transporters evolution lifestyle of plants

Upregulation of Cavin-1 mediates multidrug resistance in breast cancer cells

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Upregulation of Cavin-1 mediates multidrug resistance in bre...

Cinnamon extract suppresses experimental colitis through modulation of antigen-presenting cells

第十七届国际生物物理大会;第十二届中国生物物理大会

作者： jae-Sung Yi Young-Gyu ko College of Life Sciences and Biotechnology Korea UniversitySeoul136-701Korea

Lipid rafts and caveolae are liquid-ordered microdomains in plasma membrane composed with glycosphmgolipids and ***-1 is a major structural protein of caveolae which are important for cholesterol trafficking,vesicular... 详细信息

关键词： Lipid rafts Multidrug resistance EGFR Cavin-1 PTRF

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World Journal of Gastroenterology 2011年第8期17卷 976-986页

作者： Ho-Keun Kwon Ji-Sun Hwang Choong-Gu Lee jae-Seon So Anupama Sahoo Chang-Rok Im Won Kyung Jeon Byoung Seob ko Sung Haeng Lee Zee Yong Park Sin-Hyeog Im School of Life Sciences and Immune Synapse Research Center Gwangju Institute of Science and Technology Global leader program Bugil Academy Cheonan korea Institute of Orien-tal Medicine Chosun University School of Medicine

AIM:To investigate the anti-inflammatory effects of cinnamon extract and elucidate its mechanisms for targeting the function of antigen presenting ***:Cinnamon extract was used to treat murine macrophage cell line(Raw 264.7),mouse primary antigen-presenting cells(APCs,MHCII+) and CD11c+dendritic cells to analyze the effects of cinnamon extract on APC *** mechanisms of action of cinnamon extract on APCs were investigated by analyzing cytokine production,and expression of MHC antigens and co-stimulatory molecules by quantitative real-time PCR and flow *** addition,the effect of cinnamon extract on antigen presentation capacity and APC-dependent T-cell differentiation were analyzed by [H3]-thymidine incorporation and cytokine analysis,*** confirm the anti-inflammatory effects of cinnamon extract in vivo,cinnamon or PBS was orally administered to mice for 20 d followed by induction of experimental colitis with 2,4,6 trinitrobenzenesulfonic *** protective effects of cinnamon extract against experimental colitis were measured by checking clinical symptoms,histological analysis and cytokine expression prof iles in inflamed ***:Treatment with cinnamon extract inhibited maturation of MHCII+ APCs or CD11c+ dendritic cells(DCs) by suppressing expression of co-stimulatory molecules(B7.1,B7.2,ICOS-L),MHCII and cyclooxygenase(COX)-*** extract induced regulatory DCs(rDCs) that produce low levels of pro-inflammatory cytokines [interleukin(IL)-1β,IL-6,IL-12,interferon(IFN)-γ and tumor necrosis factor(TNF)-α] while expressing high levels of immunoregulatory cytokines(IL-10 and transforming growth factor-β).In addition,rDCs generated by cinnamon extract inhibited APC-dependent T-cell proliferation,and converted CD4+ T cells into IL-10high CD4+ T ***,oral administration of cinnamon extract inhibited development and progression of intestinal colitis by inhibiting expression of COX-2 and pro-inflammatory cytokin

关键词： Cinnamon extract Inflammation CD4 antigen Antigen presenting cells Cyclooxygenase-2 Tumor necrosis factor-α Interleukin-10 Inflammatory bowel disease

Undiagnosed Borrmann type Ⅱ gastric cancer due to necrosis and regenerative epithelium

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World Journal of Gastroenterology 2014年第28期20卷 9621-9625页

作者： Joon Hur jae Hyuck Chang Byung Kee Kim Hoon Young ko Jong Hwan Lee Soo Jeong Kim Mi Ae Song Tae Ho Kim Chang Whan Kim Sok Won Han Division of Gastroenterology Department of Internal MedicineBucheon St.Mary’s HospitalThe Catholic University of KoreaCollege of Medicine Department of Clinical Pathology Bucheon St.Mary’s HospitalThe Catholic University of KoreaCollege of Medicine

Endoscopic biopsy is essential to the proper diagnosis and treatment of gastric ***,the results of endoscopic biopsy are not always the same as what is expected based on gross endoscopic *** results of endoscopic biopsy can be negative for malignancy in Borrmann typeⅣadvanced gastric cancer(AGCa)or gastric ***,in the case of typeⅡAGCa,repeated biopsies negative for malignancy have not been reported.A 49-year-old male patient underwent esophagogastroduodenoscopy three times due to large gastric ulcer suspected to be Borrmann typeⅡ***,three repeat endoscopic biopsies with multiple specimens showed necrosis and superficial regenerative epithelium without malignant *** patient underwent laparoscopic distal gastrectomy with D2 lymph node *** surgical specimen revealed that the mucosal layer was completely replaced with regenerative epithelium without cancer cells.

关键词： Endoscopy Biopsy Stomach neoplasm Stomach ulcer Regeneration