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chromosome Substitution Lines in cotton Improvement

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棉花学报 2002年第S1期14卷 78-78页

作者： Sukumar SAHA Dwaine A.RASKA Osman A.GUTIéRREZl Johnie N.JENKINS jack c.mccarty Jr. Roy G.cANTRELL Richard G.PERcY David M.STELLY USDA-ARS Crop Science Research LaboratoryMississippi StateMS 39762 Department of Soil&crop Sciences Texas A&M UniversityCollege StationTexas 77843-2474 Department of Agronomy and Horticulture 30003Dept.3QNew Mexico State UniversityLas Cruces.NM 88003-8003 USDA-ARS Maricopa Agricultural CenterMacricopaAZ 85239USA

Presently cotton breeders are confronting seriouschallenges due to the extensive use of narrowgenetic base in Upland cotton,*** germplasm that incorporatesnew alleles must be developed to provideimproved genetic poten... 详细信息

关键词：棉花 disease resistance genetic potential Upland cotton

An Adaptive Sequential Replacement Method for Variable Selection in Linear Regression Analysis

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“机械灌注+”应用于扩大标准供肝移植--肝尽其用

Open Journal of Statistics（统计学期刊） 2023年第5期

作者： Jixiang Wu Johnie N.Jenkins jack c.mccarty Jr.

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Engineering 2024年第1期32卷 29-40页

作者： Zhoucheng Wang jack Martin Jiongjie Yu Kai Wang Kourosh Saeb-Parsy Xiao Xu Zhejiang University School of Medicine Hangzhou 310058China Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Hangzhou 310006China Department of Surgery Cambridge University Hospitals&NHS Foundation TrustCambridge CB22QQ UK Department of Surgery University of Cambridge&NIHR Cambridge Biomedical Research CentreCambridge CB22QQUK Institute of Organ Transplantation Zhejiang UniversityHangzhou 310003China

Transplantation represents the most effective treatment for end-stage liver diseases but is limited by the shortage of healthy donor *** criteria donor(EcD)liver grafts are increasingly utilized in clinical practice to mitigate this ***,impaired ischemic tolerance of these grafts jeopardizes organ viability during cold *** perfusion(MP)was designed to improve organ preservation and reduce posttransplant ***,it is increasingly evident that MP alone may not preserve EcD grafts *** emphasis has thus been placed on modified MP strategies,including the use of different perfusates,modified perfusion modalities,and different therapeutic ***,we introduce a novel term,"MP Plus,"denoting these additional strategies that are designed to restore organ function and potentially enable regeneration of EcD *** this review,we summarize the existing and potential modified MP strategies and discuss their advantages in reconditioning different EcD grafts in clinical settings.

关键词： Liver transplantation Extended criteria donor Machine perfusion plus Organ shortage

Application of the Shrinking Particle Model for the Evaluation of Molecular Recyclability of PET versus Semi-Aromatic Polyesters

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Open Journal of Physical chemistry 2024年第2期14卷 21-35页

作者： jack van Schijndel Sanne de Krom Dennis Molendijk Koen van Beurden Amarante Böttger Research Group Biopolymers/Green chemistry Centre of Expertise Safe & Resilient Society Avans University of Applied Science Breda Netherlands New Materials and Their Applications Centre of Expertise Safe & Resilient Society Avans University of Applied Science Breda Netherlands Department of Materials Science and Engineering Delft University of Technology Delft Netherlands

The molecular recyclability of poly (ethylene terephthalate) (PET) and three semi-aromatic polyesters poly (phloretic acid) (poly-H), poly (dihydroferulic acid) (poly-G), and poly (dihydrosinapinic acid) (poly-S) is evaluated in this study. PET is an extensively used aromatic polyester, and poly-H, poly-G, and poly-S can be considered semi-aromatic poly (lactic acid) modifications. All these polyesters have been depolymerized at neutral pH and by acid- and base-catalyzed hydrolysis at two temperatures, i.e., 50˚c and 80˚c. Base-catalyzed depolymerization of virgin PET leads to an isolated yield of 38% after 48 hours of reaction at 80˚c. contrary to these results for PET, almost all the monomers of the semi-aromatic polyesters poly-H, poly-G, and poly-S are recovered with isolated yields larger than 90% at the same temperature after 15 minutes in a facile manner. A shrinking particle model used to determine the global kinetics of the base-catalyzed depolymerization showed that the rate rises with increasing temperature. Using the shrinking particle model, the intrinsic reaction rate constants were determined. It has been demonstrated that the rate coefficients of the depolymerization of the semi-aromatic polyesters poly-H, poly-G, and poly-S are between 2 and 3 orders of magnitude higher than those for PET.

关键词： Depolymerization Molecular Recycling Poly-H Poly-G Poly-S PET circular Polymers

Revealing GE Interactions from Trial Data without Replications

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Open Journal of Statistics 2019年第3期9卷 407-419页

作者： Jixiang Wu Johnie Jenkins jack c. mccarty Department of Agronomy Horticulture and Plant Science South Dakota State University Brookings SD USA crop Science Research Laboratory USDA-ARS Mississippi State MS USA

Detecting genotype-by-environment (GE) interaction effects or yield stability is one of the most important components for crop trial data analysis, especially in historical crop trial data. However, it is statistically challenging to discover the GE interaction effects because many published data were just entry means under each environment rather than repeated field plot data. In this study, we propose a new methodology, which can be used to impute replicated trial data sets to reveal GE interactions from the original data. As a demonstration, we used a data set, which includes 28 potato genotypes and six environments with three replications to numerically evaluate the properties of this new imputation method. We compared the phenotypic means and predicted random effects from the imputed data with the results from the original data. The results from the imputed data were highly consistent with those from the original data set, indicating that imputed data from the method we proposed in this study can be used to reveal information including GE interaction effects harbored in the original data. Therefore, this study could pave a way to detect the GE interactions and other related information from historical crop trial reports when replications were not available.

关键词： GE Interaction Historical crop Trial Data Imputation

comparison of REML and MINQUE for Estimated Variance components and Predicted Random Effects

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Open Journal of Statistics 2016年第5期6卷 814-823页

作者： Nan Nan Johnie N. Jenkins jack c. mccarty Jixiang Wu Department of Mathematics and Statistics South Dakota State University Brookings SD USA crop Science Research Laboratory USDA-ARS Mississippi State MS USA Agronomy Horticulture and Plant Science Department South Dakota State University Brookings SD USA

Linear mixed model (LMM) approaches have been widely applied in many areas of research data analysis because they offer great flexibility for different data structures and linear model systems. In this study, emphasis is placed on comparing the properties of two LMM approaches: restricted maximum likelihood (REML) and minimum norm quadratic unbiased estimation (MINQUE) with and without resampling techniques being included. Bias, testing power, Type I error, and computing time were compared between REML and MINQUE approaches with and without jackknife technique based on 500 simulated data sets. Results showed that MINQUE and REML methods performed equally regarding bias, Type I error, and power. jackknife-based MINQUE and REML greatly improved power compared to non-jackknife based linear mixed model approaches. Results also showed that MINQUE is more time-saving compared to REML, especially with the use of resampling techniques and large data set analysis. Results from the actual cotton data analysis were in agreement with our simulated results. Therefore, jackknife-based MINQUE approaches could be recommended to achieve desirable power with reduced time for a large data analysis and model simulations.

关键词： comparison of REML and MINQUE for Estimated Variance components and Predicted Random Effects

An Adaptive Sequential Replacement Method for Variable Selection in Linear Regression Analysis

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Open Journal of Statistics 2023年第5期13卷 746-760页

作者： Jixiang Wu Johnie N. Jenkins jack c. mccarty Jr. Genetics and Sustainable Agriculture Research Unit USDA-ARS Mississippi State USA

With the rapid development of DNA technologies, high throughput genomic data have become a powerful leverage to locate desirable genetic loci associated with traits of importance in various crop species. However, current genetic association mapping analyses are focused on identifying individual QTLs. This study aimed to identify a set of QTLs or genetic markers, which can capture genetic variability for marker-assisted selection. Selecting a set with k loci that can maximize genetic variation out of high throughput genomic data is a challenging issue. In this study, we proposed an adaptive sequential replacement (ASR) method, which is considered a variant of the sequential replacement (SR) method. Through Monte carlo simulation and comparing with four other selection methods: exhaustive, SR method, forward, and backward methods we found that the ASR method sustains consistent and repeatable results comparable to the exhaustive method with much reduced computational intensity.

关键词： Adaptive Sequential Replacement Association Mapping Exhaustive Method Global Optimal Solution Sequential Replacement Variable Selection

Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1): A Multifaceted cell Survival Factor that Drives Metabolic Disease

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Engineering 2023年第1期20卷 9-18页

作者： Tamana Yousof Jae Hyun Byun jack chen Richard c.Austin Department of Medicine Division of NephrologyMcMaster UniversityThe Research Institute of St.Joe’s Hamilton and the Hamilton Centre for Kidney ResearchHamiltonOntarioL8N 4A6Canada

Pleckstrin homology-like domain, family A, member 1 (PHLDA1) is a multifaceted intracellular protein belonging to the evolutionarily conserved pleckstrin homology-related domain family. Its murine homologue, T-cell death-associated 51 (TDAG51) gene, was initially discovered for its role in activation-induced apoptosis in T-cell hybridomas. In recent years, PHLDA1 has received increased attention due to its association with obesity, fatty liver disease, diabetes, atherosclerosis, and cancer. Accumulating evidence also supports its role in endoplasmic reticulum stress signaling pathways as a crucial mediator of apoptosis, autophagy, and cell proliferation. In this review, the current knowledge of PHLDA1 gene and protein regulation, localization, and function is summarized. This review highlights the pro- and anti-apoptotic roles of PHLDA1 that contribute to vast array of metabolic diseases.

关键词： ER-stress Metabolism Apoptosis cell survival PHLDA1

The influence of moisture on the permeability of crushed shale samples

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Petroleum Science 2019年第3期16卷 492-501页

作者： Mercy Achang jack c.Pashin Eliot A.Atekwana Boone Pickens School of Geology Oklahoma State UniversityStillwater OK 74078USA Department of Geological Sciences University of DelawareNewarkDE 19716IJSA

Shale cuttings and cores recovered from the subsurface and stored for hours to decades tend to dry out and lose moisture and hydrocarbons,leading to an increase in the effective matrix *** loss in shale samples is a fundamental sample preservation problem which can be solved by applying a standard moisture equilibration procedure to restore lost *** aim was to investigate the relationship between permeability and variable moisture as-received,as-received moisture-equilibrated and saturated moisture-equilibrated *** were crushed to a series of particle sizes(0.6-2.0)mm and moisture equilibrated at 97% relative *** show that moisture equilibration in the samples was achieved after 72 *** permeability of the saturated moisture-equilibrated and as-received moisture-equilibrated samples decreased exponentially with increase in moisture *** high correlation coefficient between permeability and particle size(r = 0.96 and 0.97)for moisture-equilibrated samples compared to 0.76 for as-received samples indicates that moisture equilibration improves permeability measurements in crushed shale ***,permeability measurements are repeatable for moisture-equilibrated samples compared to samples that were not equilibrated(as-received).We conclude that moisture content affects permeability and moisture equilibration normalizes and improves the repeatability of permeability measurements in crushed shale.

关键词： crushed shale Matrix permeability Moisture equilibration