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Women's health and Chinese integrative medicine

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journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2017年第3期18卷 183-185页

作者： Fan QU Fang-fang WANG Nicola ROBINSON paul j.HARDIMAN Women's Hospital School of Medicine Zhejiang University School of Health and Social Care London South Bank University Institute for Women's Health University College London Medical School

Researchers in the fields of obstetrics, gynecology, and Chinese integrative medicine （CIM） were invited to share their perspectives on the most recent studies.

关键词：女性健康中西医结合医学妇产科学

Histogram Matched Chest X-Rays Based Tuberculosis Detection Using CNN

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Computer Systems Science & Engineering 2023年第1期44卷 81-97页

作者： joe Louis paul Ignatius Sasirekha Selvakumar Kavin Gabriel joe Louis paul Aadhithya B.Kailash S.Keertivaas S.A.j.Akarvin Raja Prajan Department of Information Technology Sri Sivasubramaniya Nadar College of EngineeringRajiv Gandhi Salai(OMR)KalavakkamChennai603110Tamil NaduIndia Gullas College of Medicine-University of Visayas BaniladMandaue City6014CebuPhilippines

Tuberculosis(TB)is a severe infection that mostly affects the lungs and kills millions of people’s lives every *** can be diagnosed using chest X-rays(CXR)and data-driven deep learning(DL)*** of its better automated feature extraction capability,convolutional neural net-works(CNNs)trained on natural images are particularly effective in image cate-gorization.A combination of 3001 normal and 3001 TB CXR images was gathered for this study from different accessible public *** different deep CNNs(Resnet50,Resnet101,Resnet152,InceptionV3,VGG16,VGG19,DenseNet121,DenseNet169,DenseNet201,MobileNet)are trained and tested for identifying TB and normal *** study presents a deep CNN approach based on histogram matched CXR images that does not require object segmenta-tion of interest,and this coupled methodology of histogram matching with the CXRs improves the accuracy and detection performance of CNN models for TB ***,this research contains two separate experiments that used CXR images with and without histogram matching to classify TB and non-TB CXRs using deep *** was able to accurately detect TB from CXR images using pre-processing,data augmentation,and deep CNN *** histogram matching the best accuracy,sensitivity,specificity,precision and F1-score in the detection of TB using CXR images among ten models are 99.25%,99.48%,99.52%,99.48%and 99.22%*** histogram matching the best accuracy,sensitivity,specificity,precision and F1-score are 99.58%,99.82%,99.67%,99.65%and 99.56%*** proposed meth-odology,which has cutting-edge performance,will be useful in computer-assisted TB diagnosis and aids in minimizing irregularities in TB detection in developing countries.

关键词： Tuberculosis detection chest x-ray(CXR) convolutional neural networks(CNNs) transfer learning histogram matching

Chemical and physical variations of cannabis smoke from a variety of cannabis samples in New Zealand

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Forensic Sciences Research 2019年第2期4卷 168-178页

作者： Thomas j.Sheehan Hilary j.Hamnett Richard Beasley paul S.Fitzmaurice Toxicology Institute of Environmental Science and Research(ESR)PoriruaNew Zealand Medical Research Institute of New Zealand WellingtonNew Zealand Toxicology Unit Imperial College LondonLondonUK. Gribbles Veterinary Palmerston NorthNew Zealand

Studies have compared the chemical properties of tobacco smoke to those of cannabis smoke,with the objective of identifying the chemical attributes responsible for the mutagenicity and carcinogenicity of cannabis *** studies have included small sample sizes and produced conflicting *** aim of this study was to assess the major chemical and physical variations of cannabis smoke across a range of cannabis samples of different potencies and origins,sourced from the illegal market in New *** cannabis samples were studied ranging from 1.0%to 13.4%delta-9-tetrahydrocannabinol(D9THC)content.A smoking machine was used to smoke“joints”(cannabis cigarettes)and the chemical/physical properties of the smoke *** chemical constituents of the smoke extracts were analysed by gas chromatography/mass spectrometry.A range of different chemical constituents(in addition to D9THC)were identified and their concentrations *** were identified as the major variable in cannabis smoke,showing a 40-fold range in total terpenoid *** of the total particulate matter showed that significantly different levels of particulate matter were produced between the different cannabis samples,ranging from 14.6 to 66.3 mg/g of cannabis *** D9THC delivery efficiency during smoking was also investigated and produced consistent results showing a mean and median of 12.6%and 10.8%,respectively,of the theoretically available D9THC(ranging from 7.2%to 28.0%).

关键词： Forensic science forensic toxicology cannabis smoke delta-9-tetrahydrocannabinol terpenoids gas chromatography/mass spectrometry total particulate matter

Effect of time-of-day and day-of-the-week on congestion duration and breakdown:A case study at a bottleneck in Salem,NH

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journal of Traffic and Transportation Engineering(English Edition) 2017年第1期4卷 31-40页

作者： Eric M.Laflamme paul j.Ossenbruggen Department of Mathematics Plymouth State UniversityPlymouthNH 03264USA Department of Mathematics and Statistics University of New HampshireDurhamNH 03824USA

This work uses regression models to analyze two characteristics of recurrent congestion： breakdown, the transition from freely flowing conditions to a congested state, and duration, the time between the onset and clearance of recurrent congestion. First, we apply a binary logistic regression model where a continuous measurement for traffic flow and a dichoto- mous categorical variable for time-of-day （AM- or PM-rush hours） is used to predict the probability of breakdown. Second, we apply an ordinary least squares regression model where categorical variables for time-of-day （AM- or PM-rush hours） and day-of-the-week （Monday-Thursday or Friday） are used to predict recurrent congestion duration. Models are fitted to data collected from a bottleneck on 1-93 in Salem, NH, over a period of 9 months. Results from the breakdown model, predict probabilities of recurrent congestion, are consistent with observed traffic and illustrate an upshift in breakdown probabilities between the AM- and PM-rush periods. Results from the regression model for congestion duration reveal the presences of significant interaction between time-of-day and day-of-the-week. Thus, the effect of time-of-day on congestion duration depends on the day-of-the-week. This work provides a simplification of recurrent congestion and recovery, very noisy processes. Simplification, conveying complex relationships with simple statistical summaries-facts, is a practical and powerful tool for traffic administrators to use in the decision-making process.

关键词： Stochastic models Ordinary least squares regression Binary logistic regression Congestion duration Breakdown

Mortality and health care burden of Budd Chiari syndrome in the United States:A nationwide analysis(1998-2017)

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World journal of Hepatology 2021年第6期13卷 686-698页

作者： joseph j Alukal Talan Zhang paul joseph Thuluvath Institute of Digestive Health and Liver Diseases Mercy Medical CenterBaltimoreMD 21202United States Department of Medicine University of Maryland School of MedicineBaltimoreMD 21202United States

The Budd Chiari syndrome(BCS)is a rare and potentially fatal disease,but there is a paucity of data on the in-hospital mortality as well its economic burden on the health care *** To evaluate trends in mortality,length of hospital stays and resource utilization among inpatients with *** Data on all adult patients with a diagnosis of BCS were extracted from the National Inpatient Sample(NIS)from 1998 to *** make inferences regarding the national estimates for the total number of BCS discharges across the study period,sample weights were applied to each admission per recommendations from the *** During the study period,there were 3591(8.73%)in-patient *** overall inhospital mortality rates among BCS patients decreased from 18%in 1998 to 8%in 2017;the mortality decreased by 4.41%(Pjury,acute respiratory failure,hepatic encephalopathy,hepatorenal syndrome,inferior vena cava thrombosis,intestinal infarct,sepsis/septic shock and cancer were associated increased risk of *** average of length of stay was 8.8 d and it consistently decreased by 2.04%(95%CI:-2.67%,-1.41%,Pjusted for Medical Care Consumers Price Index to 2017 dollars during the time period was$94440 and the annual percentage change increased by 1.15%(95%CI:0.35%,1.96%,P=0.005)from$95515 in 1998 to$103850 in *** The in-hospital mortality rate for patients admitted with BCS in the United States has reduced between 1998 and 2017 and this may a reflection of better management of these patients.

关键词： National Inpatient Sample Budd Chiari syndrome Mortality Length of stay Total charges

Social perception of soil conservation benefits in Kondoa eroded area of Tanzania

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International Soil and Water Conservation Research 2015年第3期3卷 183-195页

作者： Rajendra P.Shrestha paul j.Ligonja Asian Institute of Technology BangkokThailand Open University of Tanzania Tanzania

A soil conservation project was implemented in Tanzania for over 30 *** study applied a socio-economic approach to examine and analyse the benefits of soil conservation in the Kondoa eroded area of Tanzania by conducting a household survey of 240 *** study findings show that 89%and 70%of respondents consider soil conservation activities have increased vegetation and soil fertility,*** soil erosion was perceived by 68%of respondents,increased firewood by 98%,increased fodder by 50%,high crop yields by 56%,and food sufficiency by 68%.These are the outcomes of conservation tillage,integrated farming and use of organic fertilizers,controlled stall feeding,agroforestry,construction of cut off drains,contour bunds and contour ridges cultivation,which are the main land use practices in the *** to extension services,household sizes,long term land ownership,crop incomes and awareness of soil conservation project were found to determine the level of participation in soil *** challenges are the lack of sustainability of those activities because of a recent policy decision to withdraw conservation *** the challenge,this study concluded that past government efforts on soil conservation activities initiated since the early 1970s through decentralization,institutional collaboration,socioeconomic support to farmers and continuous local community participation in restoring the degraded ecosystem of Kondoa have contributed to ensure environmental and socio-economic sustainability in the area.

关键词： Kondoa eroded area Environmental and livelihood sustainability Social perceptions Soil conservation

Associations between physical activity levels and ATPase inhibitory factor 1 concentrations in older adults

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journal of Sport and Health Science 2024年第3期13卷 409-418页

作者： jérémy Raffin Yves Rolland Annelise Genoux Guillaume Combes Mikael Croyal Bertrand Perret Sophie Guyonnet Bruno Vellas Laurent O.Martinez Philipe de Souto Barreto For the MAPT/DSA Group Institut du Vieillissement Gérontopôle de ToulouseCentre Hospitalo-Universitaire de ToulouseToulouse 31000France Centre d'Epidémiologie et de Recherche en Santédes Populations UnitéMixte de Recherche 1295Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse-III-Paul-SabatierToulouse 31000France LimitAging Team Institut des Maladies Métaboliques et CardiovasculairesUnitéMixte de Recherche 1297Institut National de la Santéet de la Recherche MédicaleUniversitéToulouse III-Paul SabatierToulouse 31432France Service de Biochimie Pôle de biologieHôpital de PurpanCentre Hospitalo-Universitaire de ToulouseToulouse 31300France L'Institut du Thorax Institut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France BioCore US16Structure Fédérative de Recherche BonamyInstitut National de la Santéet de la Recherche MédicaleCentre National de la Recherche ScientifiqueCentre Hospitalo-Universitaire de NantesNantes UniversitéNantes 44000France Plate-forme de spectrométrie de masse Centre de Recherche en Nutrition HumaineOuestNantes 44000France 不详

Background:Adenosine triphosphatase inhibitory factor 1(IF1)is a key protein involved in energy ***1 has been linked to various agerelated diseases,although its relationship with physical activity(PA)remains ***,the apolipoprotein A-I(apoA-I),a PA-modulated lipoprotein,could play a role in this relationship because it shares a binding site with IF1 on the cell-surface ATP *** examined here the associations between chronic PA and plasma IF1 concentrations among older adults,and we investigated whether apoA-I mediated these ***:In the present work,1096 healthy adults(63.8%females)aged 70 years and over who were involved in the Multidomain Alzheimer Prevention Trial study were ***1 plasma concentrations(square root of ng/mL)were measured at the 1-year visit of the Multidomain Alzheimer Prevention Trial,while PA levels(square root of metabolic equivalent task min/week)were assessed using questionnaires administered each year from baseline to the 3-year *** linear regressions were performed to investigate the associations between the first-year mean PA levels and IF1 *** analyses were conducted to examine whether apoA-I mediated these *** linear regressions were carried out to investigate whether the 1-year visit IF1 concentrations predicted subsequent changes in ***:Multiple linear regressions indicated that first-year mean PA levels were positively associated with IF1 concentrations(B=0.021;SE=0.010;p=0.043).Mediation analyses revealed that about 37.7%of this relationship was mediated by apoA-I(B_(ab)=0.008;SE=0.004;p=0.023).Longitudinal investigations demonstrated that higher concentrations of IF1 at the 1-year visit predicted a faster decline in PA levels over the subsequent 2 years(time×IF1:B=0.148;SE=0.066;p=0.025).Conclusion:This study demonstrates that regular PA is associated with plasma IF1 concentrations,and it suggests that apoA-I partly med

关键词： Aging Apolipoprotein Bioenergetics Exerkine Mitochondria

ADVANCED jAVA 2 PLATFORM HOW TO PROGRAM

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Bacterial diversity and distribution in the southeast edge of the Tengger Desert and their correlation with soil enzyme activities

丛书名：国外计算机科学教材系列

2004年

作者： HARVEY M.DEITEL paul j.DEITEL

来源：畅想之星图书光盘版（南... 评论

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journal of Environmental Sciences 2012年第11期24卷 2004-2011页

作者： Wei Zhang Gaosen Zhang Guangxiu Liu Zhibao Dong Tuo Chen Manxiao Zhang paul j.Dyson Lizhe An Key Laboratory of Desert and Desertification Cold and Arid Regions Environmental and Engineering Research InstituteChinese Academy of SciencesLanzhou 730000China School of Life Sciences Lanzhou UniversityLanzhou 730000China Institute of Life Science College of MedicineSwansea UniversitySwansea SA28PPUK

The nature of microbial communities and their relation to enzyme activities in desert soils is a neglected area of investigation. To address this, the bacterial diversity and distribution and soil physico-chemical factors were investigated in the soil crust, the soil beneath the crust and rhizosphere soil at the southeast edge of the Tengger Desert, using the denaturing gradient gel electrophoresis of 16S rRNA genes amplified by the polymerase chain reaction. Phylogenedc analysis of the sequenced DGGE bands revealed a great diversity of bacteria. The Proteobacteria, consisting of the α, β, and γsubdivisions, were clearly the dominant group at all depths and in rhizosphere soil. Analysis of the enzyme activities indicated that the rhizosphere soil of Caragana korshinskii exhibited the highest protease and polyphenol oxidase activities, and in the soil crust there were increased activities of catalase, urease, dehydrogenase and sucrase. The bacterial community abundance closely correlated with soil enzyme activities in different soils. The presence of Cyanobacteria correlated with significant increases in protease, catalase and sucrase in the soil crust, and increased urease in the rhizosphere soil of Artemisia ordosica. The occurrence of Acidobacteria was associated with significant increases in urease, dehydrogenase, and sucrase in the rhizosphere soil of C. korshinski. The presence of γ-Proteobacteria correlated with a significant increase in polyphenol oxidase in the rhizosphere soil ofA. ordosica. The study indicated a close relationship between the soil bacterial community and soil enzymes, suggesting the necessity of further investigations into bacterial function in this desert ecosystem.

关键词： Tengger Desert DGGE 16S rRNA bacterial community soil enzyme