检索结果-南通市图书馆

Finding biomarkers of experience in animals

journal of Animal Science and Biotechnology 2024年第3期15卷 925-944页

作者： Sarah Babington Alan j.Tilbrook Shane K.Maloney jill N.Fernandes Tamsyn M.Crowley Luoyang Ding Archa h.Fox Song Zhang Elise A.Kho Daniel Cozzolino Timothy j.Mahony Dominique Blache School of Agriculture and Environment The University of Western AustraliaCrawleyWA 6009Australia Centre for Animal Science The Queensland Alliance for Agriculture and Food InnovationThe University of QueenslandSt LuciaQLD 4072Australia School of Veterinary Science The University of QueenslandGattonQLD 4343Australia School of human Sciences The University of Western AustraliaCrawleyWA 6009Australia School of Medicine Deakin UniversityGeelongVIC 3217Australia Poultry hub Australia University of New EnglandArmidaleNSW 2350Australia College of Animal Science and Technology Yangzhou UniversityYangzhou 225009China Centre for Nutrition and Food Sciences The Queensland Alliance for Agriculture and Food InnovationThe University of QueenslandSt LuciaQLD 4072Australia

At a time when there is a growing public interest in animal welfare,it is critical to have objective means to assess the way that an animal experiences a *** is critical to ensure appropriate animal welfare *** behavioural,physiological,and neurobiological indicators that are used to assess animal welfare can verify the absence of extremely negative *** welfare is more than an absence of negative outcomes and an appropriate indicator should reflect the full spectrum of experience of an animal,from negative to *** this review,we draw from the knowledge of human biomedical science to propose a list of candidate biological markers(biomarkers)that should reflect the experiential state of non-human *** proposed biomarkers can be classified on their main function as endocrine,oxidative stress,non-coding molecular,and thermobiological *** also discuss practical challenges that must be addressed before any of these biomarkers can become useful to assess the experience of an animal in real-life.

关键词： Animal experience Animal welfare Biomarker Stress Welfare assessment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Extreme Antarctic Cold of Late Winter 2023

引用

Advances in Atmospheric Sciences 2024年第10期41卷 1873-1880页

作者： Anastasia j.TOMANEK David E.MIKOLAjCZYK Matthew A.LAZZARA Stefano DI BATTISTA Minghu DING Mariana FONTOLAN LITELL David h.BROMWICh Taylor P.NORTON Linda M.KELLER Lee j.WELhOUSE Antarctic Meteorological Research and Data Center Space Science and Engineering CenterUniversity of Wisconsin-MadisonMadisonWisconsin 53706USA Department of Physical Sciences School of EngineeringScienceand MathematicsMadison Area Technical CollegeMadisonWisconsin 53704USA Meteogiornale via Paolo Diacono9Milano 20133Italy State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China Byrd Polar and Climate Research Center The Ohio State UniversityColumbusOhio 43210USA Department of Geography The Ohio State UniversityColumbusOhio 43210USA

Extreme cold temperatures were observed in july and August 2023,coinciding with the WINFLY(winter fly-in)period of mid to late August into September 2023,meaning aircraft operations into McMurdo Station and Phoenix Airfield were adversely ***,with temperatures below−50℃,safe flight operation was not possible because of the risk of failing hydraulics and fuel turning to gel onboard the *** cold temperatures were measured across a broad area of the Antarctic,from East Antarctica toward the Ross Ice Shelf,and stretching across West Antarctica to the Antarctic Peninsula.A review of automatic weather station measurements and staffed station observations revealed a series of sites recording new record low *** separate cold phases were identified,each a few days in duration and occurring from mid-july to the end of August 2023.A brief analysis of 500-hPa geopotential height anomalies shows how the mid-tropospheric atmospheric environment evolves in relation to these extreme cold *** monthly 500-hPa geopotential height anomalies show strong negative anomalies in *** of composite geopotential height anomalies during each of the four cold phases suggests various factors leading to cold temperatures,including both southerly off-content flow and calm atmospheric *** the atmospheric environment that leads to such extreme cold temperatures can improve prediction of such events and benefit Antarctic operations and the study of Antarctic meteorology and climatology.

关键词： Antarctica extreme cold temperature automatic weather station networks

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

ENSO impacts on litter stocks and water holding capacity in secondary forests in eastern Amazonia

引用

journal of Forestry Research 2024年第1期35卷 83-89页

作者： julia Isabella de Matos Rodrigues Walmer Bruno Rocha Martins Victor Pereira de Oliveira Myriam Suelen da Silva Wanzerley hélio Brito dos Santos júnior Francisco de Assis Oliveira Graduate Program in Forestry Sciences Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Av.Presidente Tancredo Neves2501BelémPará66077-530Brazil Federal Rural University of Amazonia Tv.Pau-AmareloCapitão PoçoPará68650-000Brazil National Institute of Amazonia Research Av.Constelação Cruzeiro do SulManausAmazonas 69060-062Brazil

Among the impacts of climate change,there is the intensification of phenomena such as the El Niño South-ern Oscillation(ENSO)responsible for El Niño and La Niñ***,understanding their effects on the functional pro-cesses of forests is ***,this study evaluated the effects of ENSO on litter stock and water holding capac-ity(WhC)in a successional forest in eastern *** occurred in periods with the most rainfall in El Niño(2019)and least in La Niña(2021)*** permanent plots were used to sample *** effects were evident for WhC,higher during El Niñ***,this influence was not clear for litter,as only in the rainy season effects were *** was a positive correlation of WhC with precipitation and humidity,while litter stocks were negatively correlated with temperature and wind *** the subject of this study requires long-term assessments,preliminary results suggests that,depending on the intensity of ENSO,forest functional processes can be strongly impacted and *** conclusion reinforces warnings by the scientific community about the impacts of climate change on the maintenance of litter stocks,decomposition and,consequently,the biogeochemical cycle and essential ecosystem services for the maintenance of Amazonia *** need to develop long-term research to understand the effects of climatic change on litter stocks and water holding capacity is highlighted,especially in Amazonia.

关键词： Seasonality Climate change Succession ecosystem Biogeochemical cycle Amazonia biodiversity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Investigation of hCAR2 antagonists as a potential strategy to modulate bovine leukocytes

引用

journal of Animal Science and Biotechnology 2024年第4期15卷 1567-1577页

作者： Laman K.Mamedova Kirby C.Krogstad Paiton O.McDonald Laxman Pokhrel Duy h.hua Evan C.Titgemeyer Barry j.Bradford Department of Animal Science Michigan State UniversityEast LansingMichigan 48824USA Department of Animal Sciences and Industry Kansas State UniversityManhattanKS 66506USA Comparative Medicine and Integrative Biology East LansingMI 48824USA Department of Chemistry Kansas State UniversityManhattanKS 66506USA

Background Dairy cows experiencing ketosis after calving suffer greater disease incidence and are at greater risk of leaving the herd. In vitro administration of beta-hydroxybutyric acid(BhBA;the primary blood ketone) has inhibitory effects on the function of bovine leukocytes. BhBA is a ligand of hCAR2 and the activation of these receptors promotes an anti-inflammatory response which may be related with immunosuppression observed in transition dairy cattle. The objective of this study was to identify and test antagonists for hCAR2 in bovine immune cells cultured with *** We observed expression of hCAR2 at the protein level within lymphocytes, monocytes, and granulocytes. The proportion of cells expressing hCAR2 tended to be greater in mid-lactation compared to early lactation cows;the increase was a result of increased proportion of T and B cells expressing hCAR2. Stimulation of hCAR2 with niacin or BhBA promoted Ca^(2+) mobilization in neutrophils and mononuclear cells. Mononuclear cells treated with BhBA had diminished intracellular Ca^(2+) responses when hCAR2 was knocked down by si RNA silencing, indicating Ca^(2+) mobilization was mediated by hCAR2 signaling. Two candidate antagonists for hCAR2, synthesized from niacin(NA-1 and NA-5), were tested;monocytes and neutrophils pre-treated with NA-1 and NA-5 had reduced Ca^(2+) mobilization after incubation with BhBA. Furthermore, NA-5 but not NA-1 prevented BhBA-associated reductions in cyclic *** We demonstrated that hCAR2 is present on bovine leukocytes and has greater expression later in lactation. We confirmed that BhBA and niacin derived hCAR2 antagonists alter bovine leukocyte activity. Our results demonstrate that both BhBA and niacin affect bovine leukocyte Ca^(2+) mobilization in a hCAR2-dependent manner.

关键词： Flow cytometry GPR109A hM74A Ketosis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

用于诊断肝细胞癌的肝脏影像报告及数据系统2018版5类：一项最新Meta分析

引用

国际医学放射学杂志 2024年第3期 373-374页

作者： S.Lee Y.Y.Kim j.Shin Y.h.Roh j.Y.Choi V.Chernyak 吴玉平

摘要目的该项更新的Meta分析旨在确定使用肝脏影像报告和数据系统（LI-RADS）2018版本（v2018）的LI-RADS LR-5类对肝细胞癌（hCC）的诊断能力，并通过评估成像方

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Obstructive sleep apnea:Overlooked comorbidity in patients with diabetes

引用

World journal of Diabetes 2024年第7期15卷 1448-1460页

作者： Eric D Tenda joshua henrina jin h Cha Muhammad R Triono Ersananda A Putri Dahliana j Aristy Dicky L Tahapary Division of Respirology and Critical Care Department of Internal MedicineFaculty of Medicine Universitas Indonesia-Cipto Mangunkusumo HospitalDKI JakartaJakarta Pusat 10430Indonesia head of Research Group Artificial Intelligence and Digital health Indonesian Medical Education and Research InstituteFaculty of Medicine University of IndonesiaDKI JakartaJakarta Pusat 10430Indonesia Division of Endocrinology Metabolism and DiabetesDepartment of Internal MedicineFaculty of Medicine Universitas Indonesia-Cipto Mangunkusumo HospitalDKI JakartaJakarta Pusat 10430Indonesia

In this review article,we explore the interplay between obstructive sleep apnea(OSA)and type 2 diabetes mellitus(T2DM),highlighting a significant yet often overlooked *** delve into the pathophysiological links between OSA and diabetes,specifically how OSA exacerbates insulin resistance and disrupts glucose *** research examines the prevalence of OSA in diabetic patients and its role in worsening diabetes-related *** the importance of comprehensive management,including weight control and positive airway pressure therapy,the study advocates integrated approaches to improve outcomes for patients with T2DM and *** review underscores the necessity of recognizing and addressing OSA in diabetes care to ensure more effective treatment and better patient outcomes.

关键词： Obstructive sleep apnea Type 2 diabetes mellitus Macrovascular Microvascular Weight loss Positive airway pressure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

抑菌性芽孢杆菌的筛选及特性研究

引用

饲料研究 2024年第9期47卷 99-105页

作者：余梦博谢志恒黎家明李汶潓顾万军周淑贞马驿广东海洋大学滨海农业学院动物医学系广东湛江524088 佛山市南海东方澳龙制药有限公司广东佛山528234

试验旨在从自然环境中筛选出具有抑菌效果的有益菌株,对其生长特性进行初步研究。试验以大肠杆菌为指示菌对12株芽孢杆菌进行初筛,筛选出6株具有抑菌活性的芽孢杆菌并对其进行鉴定。再以大肠杆菌和金黄色葡萄球菌做指示菌,对芽孢杆菌抗... 详细信息

试验旨在从自然环境中筛选出具有抑菌效果的有益菌株,对其生长特性进行初步研究。试验以大肠杆菌为指示菌对12株芽孢杆菌进行初筛,筛选出6株具有抑菌活性的芽孢杆菌并对其进行鉴定。再以大肠杆菌和金黄色葡萄球菌做指示菌,对芽孢杆菌抗菌肽提取物进行抑菌性筛选,并对筛选出的菌株进行溶血性比较、药物敏感性测定及生长特性研究。结果显示,从实验室分离筛选出具有较强抑菌活性的菌株为芽孢杆菌G02和j12,经鉴定为暹罗芽孢杆菌(Bacillus siamensis);筛选出两株芽孢杆菌的提取物均具有分泌表面活性的能力,且分泌表面活性的能力相当;两株芽孢杆菌对16种药物的敏感性均在中敏以上;两菌株在6 h进入生长对数期,ph值维持在5~8之间,抑菌性在22 h达到高峰。研究表明,芽孢杆菌具有产生多种活性肽的能力,对常见病原菌具有一定的抑制作用,是一种潜在的传统抗生素替代品。

关键词：芽孢杆菌抑菌性筛选生长特性

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于ORF3蛋白抗体的鹅圆环病毒间接ELISA检测方法的建立

引用

农业生物技术学报 2024年第3期32卷 730-738页

作者：付环茹赵敏江锦秀陈翠腾张靖鹏李兆龙万春和福建省农业科学院畜牧兽医研究所福建农林大学生命科学学院福建省禽病防治重点实验室/福建省畜禽遗传育种重点实验室/福建省畜禽疫病防治工程技术研究中心

鹅圆环病毒(Goose circovirus, GoCV)是一种潜在的免疫抑制病原，主要感染宿主淋巴细胞，导致免疫功能下降，易造成其他病原继发感染，给养鹅(Anser cygnoides orientalis)业带来极大危害。为建立鹅圆环病毒血清学抗体的间接ELISA方法... 详细信息

鹅圆环病毒(Goose circovirus, GoCV)是一种潜在的免疫抑制病原，主要感染宿主淋巴细胞，导致免疫功能下降，易造成其他病原继发感染，给养鹅(Anser cygnoides orientalis)业带来极大危害。为建立鹅圆环病毒血清学抗体的间接ELISA方法，本研究将GoCV的ORF3基因插入到原核表达载体p ET-32a(+)，构建重组质粒pET-32a-ORF3，经表达条件优化，以Ni柱亲和层析纯化目的蛋白，SDS-PAGE和Western blot分析表明，获得的重组ORF3蛋白具有良好的生物学活性。以纯化后的重组ORF3蛋白作为包被抗原，通过优化各反应条件建立了GoCV间接ELISA抗体检测方法。优化后的间接ELISA检测条件为：重组ORF3蛋白的最佳包被浓度为2.00μg/mL、待检血清稀释度为1∶80、酶标二抗最佳稀释度分别为1∶4 000 (羊抗鸡hRP-IgG)和1∶8 000 (羊抗鸭hRP-IgG)。采用建立的间接ELISA方法对鹅细小病毒(Goose parvovirus,GPV)、鹅源禽坦布苏病毒(Avian tembusu virus, ATmV)、鹅源h9N2亚型禽流感病毒(h9N2 subtype avian influenza virus, AIV)、鹅呼肠孤病毒(Goose reovirus, GRV)、新型鹅星状病毒(Goose astrovirus, GoAstV)、GoCV等鹅源阳性血清进行检测，结果显示，仅GoCV阳性血清为阳性结果，其他病原阳性血清检测结果均为阴性，特异性较强；重复性较好，批内和批间变异系数均小于5%。流行病学调查结果显示，福建和广东地区鸭(Anatinae)群中均存在GoCV跨种感染。本研究建立的检测GoCV血清抗体的间接ELISA方法特异性强、重复性好，可用于GoCV感染的诊断及流行病学调查研究。

关键词：鹅圆环病毒(GoCV) ORF3蛋白原核表达间接ELISA 流行病调查

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

古北口长城景观视觉感知区位数据集

引用

全球变化数据学报（中英文） 2024年第1期8卷 32-41,V0032-V0041页

作者：李照航李仁杰孙宝磊李家慧河北师范大学地理科学学院石家庄050024 河北师范大学地理计算与规划研究中心石家庄050024 河北省环境变化遥感识别技术创新中心石家庄050024

长城是具有历史文化、形态美学等多重意义的重要视觉景观资源,视觉感知计算分析是挖掘长城景观资源价值,呈现和阐释长城多维意义的重要路径。通过设计长城景观系统的语义特征点提取和编码规则,基于古北口长城资源本体和ALOS 12.5 m DEM... 详细信息

长城是具有历史文化、形态美学等多重意义的重要视觉景观资源,视觉感知计算分析是挖掘长城景观资源价值,呈现和阐释长城多维意义的重要路径。通过设计长城景观系统的语义特征点提取和编码规则,基于古北口长城资源本体和ALOS 12.5 m DEM数据生成了景观语义特征点,并对每个特征点进行视域分析得到可视域栅格;以景观视觉感知区位信息模型(LVPLM)为基础,选择NetCDF多维数据格式建立了古北口长城景观视觉感知区位数据集。数据集包括3部分:(1)人工选择语义特征点数据子集;(2)程序自动选择语义特征点数据子集;(3)验证点数据。(1)和(2)数据子集内容包括:(a)古北口长城本体要素与语义特征点矢量数据;(b)古北口长城景观视觉感知区位数据。数据集存储为.shp和.nc格式,由64个数据文件组成,数据量为6.58 GB(压缩为1个文件,63.8 MB)。

关键词：视觉感知区位景观语义特征点长城 NetCDF

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

胆道纤维化的发生发展与治疗

引用

中华消化外科杂志 2024年第7期23卷 989-1000页

作者：赵进玉林延延岳平姚佳米宁宁李麻图付文康高龙 Azumi Suzuki Peng F Wong Kiyohito Tanaka Rungsun Rerknimitr henrik h junger Tan T Cheung Emmanuel Melloul Nicolas Demartines joseph W Leung 袁金秋 hans j Schlitt 孟文勃兰州大学第一临床医学院兰州730030 兰州大学第一医院普通外科兰州730030 浜松医学中心消化科日本浜松432-8002 詹姆斯库克大学医院血管外科英国米德尔斯堡TS43BW 京都第二红十字医院消化科日本京都602-8031 朱拉隆功国王纪念医院胃肠内镜卓越中心泰国曼谷10330 雷根斯堡大学医学中心外科德国雷根斯堡93053 香港大学外科学系中国香港999077 洛桑大学医院内脏外科瑞士洛桑CH-1015 加州大学戴维斯分校医学中心和萨克拉门托退伍军人医学中心胃肠肝病科美国萨克拉门托95817 中山大学附属第七医院临床研究中心深圳518107

胆道纤维化(BF)是病理性胆道损伤修复的结果,主要表现为胆管壁的增厚硬化和管腔的进行性狭窄,最终可能导致胆道梗阻、胆汁性肝硬化、肝衰竭、肝胆恶性肿瘤等严重不良结局。目前的研究将BF描述为某些胆管病的病理特征,对其病因、病理生... 详细信息

胆道纤维化(BF)是病理性胆道损伤修复的结果,主要表现为胆管壁的增厚硬化和管腔的进行性狭窄,最终可能导致胆道梗阻、胆汁性肝硬化、肝衰竭、肝胆恶性肿瘤等严重不良结局。目前的研究将BF描述为某些胆管病的病理特征,对其病因、病理生理、分子机制和治疗缺乏系统总结。BF是胆道系统普遍存在但容易被忽略的疾病状态,可能通过病理性胆道损伤后的异常修复机制促进肝胆疾病的发生和进展,笔者结合国内外最新研究进展,综述BF的概念、临床表现、病因、发病机制和治疗策略,为临床医师提供参考。

关键词：胆道疾病纤维化胆管反应病因信号通路治疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：