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原发性鼻咽癌MRI与内镜及内镜活检诊断正确性的对照研究

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国际医学放射学杂志 2011年第2期 183-183页

作者： A.D.king A.C.Vlantis k.s.s.Bhatia B.C.Y.Zee j.k.s.woo G.M.k.Tse 唐光健 Department of Diagnostic Radiology & Organ Imaging Faculty of Medicinethe Chinese University of Hong KongPrince of Wales Hospital

目的对照MRI与目前内镜与内镜活检临床标准的正确性,确定MRI可否发现内镜与内镜活检漏诊的亚临床癌,以及MRI能否确定没有鼻咽癌(NPC)不需要接受有创

关键词：鼻咽癌 NPC 内镜内镜活检 MRI

Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia s.Rex David j.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National science Foundation(NsF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

Combinatorial therapies for spinal cord injury repair

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Neural Regeneration Research 2025年第5期20卷 1293-1308页

作者： Carla s.sousa Andreia Monteiro António j.salgado Nuno A.silva Life and Health sciences Research Institute(ICVs) School of MedicineUniversity of MinhoCampus de Gualtar-gualtarBragaPortugal ICVs/3B’s Associate Lab PT Government Associated LabCampus de Gualtar-gualtarBragaPortugal

spinal cord injuries have profound detrimental effects on individuals, regardless of whether they are caused by trauma or non-traumatic events. The compromised regeneration of the spinal cord is primarily attributed to damaged neurons, inhibitory molecules, dysfunctional immune response, and glial scarring. Unfortunately, currently, there are no effective treatments available that can fully repair the spinal cord and improve functional outcomes. Nevertheless, numerous pre-clinical approaches have been studied for spinal cord injury recovery, including using biomaterials, cells, drugs, or technological-based strategies. Combinatorial treatments, which target various aspects of spinal cord injury pathophysiology, have been extensively tested in the last decade. These approaches aim to synergistically enhance repair processes by addressing various obstacles faced during spinal cord regeneration. Thus, this review intends to provide scientists and clinicians with an overview of pre-clinical combinatorial approaches that have been developed toward the solution of spinal cord regeneration as well as update the current knowledge about spinal cord injury pathophysiology with an emphasis on the current clinical management.

关键词： electric stimulation neural tissue regeneration neuroprotection polytherapy spinal cord injury

Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： William j.Flerlage Mark L.Dell’Acqua Brian M.Cox Fereshteh s.Nugent Uniformed services University of the Health sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AkAPs).

关键词： function supporting

Indium doping effect on properties of ZnO nanoparticles synthesized by sol–gel method

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Chinese Physics B 2019年第4期28卷 342-348页

作者： s Mourad j El Ghoul k Omri k khirouni Laboratory of Physics of Materials and Nanomaterials Applied at Environment (LaPhyMNE) Faculty of Sciences in Gabes Gabes University Imam Mohammad Ibn saud Islamic University (IMsIU) College of Sciences Department of Physics

Pure ZnO and indium-doped ZnO(In–ZO) nanoparticles with concentrations of In ranging from 0 to 5% are synthesized by a sol–gel processing technique. The structural and optical properties of ZnO and In–ZO nanoparticles are characterized by different techniques. The structural study confirms the presence of hexagonal wurtzite phase and indicates the incorporation of In^(3+) ions at the Zn^(2+) sites. However, the optical study shows a high absorption in the UV range and an important reflectance in the visible range. The optical band gap of In–ZnO sample varies between 3.16 e V and 3.22 e V. The photoluminescence(PL) analysis reveals that two emission peaks appear: one is located at 381 nm corresponding to the near-band-edge(NBE) and the other is observed in the green region. The aim of this work is to study the effect of indium doping on the structural, morphological, and optical properties of ZnO nanoparticles.

关键词： In-doped ZnO nanoparticles sol–gel process structural and optical characterization

A systematic review of progenitor survival and maturation in Parkinsonian models

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Neural Regeneration Research 2025年第11期20卷 3172-3178页

作者： Giulia Comini Eilís Dowd Pharmacology&Therapeutics and Galway Neuroscience Center University of GalwayGalwayIreland

stem cell-based brain repair is a promising emergent therapy for Parkinson's disease based on years of foundational research using human fetal donors as a cell *** current therapeutic options for patients,this approach has the potential to provide longterm stem cell–derived reconstruction and restoration of the dopaminergic input to denervated regions of the brain allowing for restoration of certain functions to *** ultimate clinical success of stem cell–derived brain repair will depend on both the safety and efficacy of the approach and the latter is dependent on the ability of the transplanted cells to survive and differentiate into functional dopaminergic neurons in the Parkinsonian *** the pre-clinical literature suggests that there is considerable variability in survival and differentiation between studies,the aim of this systematic review was to assess these parameters in human stem cell-derived dopaminergic progenitor transplant studies in animal models of Parkinson's disease.A defined systematic search of the PubMed database was completed to identify relevant studies published up to March *** screening,76 articles were included in the analysis from which 178 separate transplant studies were *** these,graft survival could be assessed in 52 studies and differentiation in 129 ***,we found that graft survival ranged froms transplanted,with a median of 51%of transplanted cells surviving in the brain;while dopaminergic differentiation of the cells ranged from 0% to 46% of cells transplanted with a median of 3%.This systematic review suggests that there is considerable scope for improvement in the differentiation of stem cell-derived dopaminergic progenitors to maximize the therapeutic potential of this approach for patients.

关键词： cell replacement therapy differentiation embryonic stem cells graft induced pluripotent stem cells Parkinson's disease survival transplant

Comparative analysis of entanglement measures based on monogamy inequality

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Chinese Physics B 2017年第5期26卷 52-59页

作者： P j Geetha sudha k s Mallesh Department of Physics Kuvempu University Shankaraghatta Shimoga-577 451 India Inspire Institute Inc. Alexandria Virginia 22303 USA Department of studies in Physics University of Mysore Mysore-570 006 India

We evaluate the monogamy inequality for symmetric, non-symmetric pure states of importance in terms of squared concurrence, squared entanglement of formation, squared negativity of partial transpose and compare the corresponding tangles. We show that though concurrence and concurrence tangle are zero for two special classes of mixed entangled states, both negativity tangle and entanglement of formation（EOF） tangle turn out to be non-zero. A comparison of different tangles is carried out in each case and it is shown that while the concurrence tangle captures the genuine multiqubit entanglement in N-qubit pure states with N distinct spinors（containing GHZ and superposition of W-, obverse W states）either negativity tangle or EOF tangle is to be used as a better measure of entanglement in the W-class of states with two distinct spinors and in the special classes of mixed multiqubit states.

关键词： entanglement tangle negativity superposition inequality entangled symmetric vanishing squared arbitrary

VRs-DB:preserve confidentiality of users'data using encryption approach

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Digital Communications and Networks 2021年第1期7卷 62-71页

作者： j.s.Rauthan k.s.Vaisla Department of Computer and science Engineering Uttarakhand Technical UniversityDehradunUttarakhand248007India

We focus on security and privacy problems within a cloud database framework,exploiting the DataBase as a service(DBaas).In this framework,an information proprietor drives out its information to a cloud database professional *** Data-Owner(DO)encrypts the delicate information before transmission at the cloud database professional company end to offer information *** encryption ideas,nonetheless,are just halfway homomorphic as all of them intend to enable an explicit kind of calculation,which is accomplished on scrambled *** current plans can't be coordinated to solve genuine functional queries that include activities of various *** propose and evaluate a Verifiable Reliable secure-DataBase(VRs-DB)framework on shared tables along with many primary operations on scrambled information,which enables information interoperability,and permits an extensive possibility of structured Query Language(sQL)queries to be prepared by the service provider on the encoded *** show that our security and privacy idea is protected from two forms of threats and are fundamentally proficient.

关键词： Privacy security Cloud storage Encrypted query Cryptography sensitive data

spontaneous ethanol-water emulsification as a precursor for porous particle formation: Understanding the role of dissolved carbohydrates

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Particuology 2019年第3期17卷 44-53页

作者： P.L. Xiao s. Mansouri V. suriya Hena Y.k. Bong k. Hapgood M.W. woo Department of Chemical Engineering Faculty of Engineering Monash University Clayton Campus Australia Powder Metallurgy Research Institute Central South University China Faculty of science Engineering &Bu ε Environment School of Engineering Deakin University Geelong Waum Ponds Campus Australia

Quiescent mixing of aqueous lactose solution with ethanol by gentle pouring allowed controlled observation of a transient, spontaneous emulsification process between ethanol and water. This phenomenon contrasts with the conventional stable phase-separation process for ethanol-water systems with other solutes. The presence of lactose in the dissolved state was deduced to be the key factor causing spontaneous emulsification. This explains the transitional behavior of the phenomenon. Further experiments with aqueous maltodextrin solution, using the same experimental technique, confirmed this phenomenon. The mechanisms determined in this work will form the basis of porous-particle synthesis via the antisolvent vapor-precipitation technique.

关键词： spontaneous emulsification Ethanol Lactose Precipitation Crystals Droplets