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Express,on of the novel adipokine ClqTNF-related protein 4 （CTRP4） suppresses colitis and colitis- associated colorectal cancer in mice

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Cellular & Molecular Immunology 2016年第5期13卷 688-699页

作者： Yang Luo Xiaotong Wu Zhuang Ma Weifeng Tan Lanlan Wang Daxiang Na Guoying Zhang ang Yin He Huang Dan Xia Yingmei Zhang Xueying Shi Lu Wang Department of Immunology Key Laboratory of Medical Immunology (Ministry of Health) School of Basic Medical Sciences Peking University Health Science Center Beijing 100191 China Department of Pathology School of Basic Medical Sciences Peking University Health Science Center Beijing 100191 China These authors contributed equally to the article. Correspondence: Dr L Wang MD PhD Department of Immunology Key Laboratory of Medical Immunology (Ministry of Health) School of Basic Medical Sciences Peking University Health Science Center 38# Xueyuan Road Beijing 100191 China

Inflammatory bowel disease （IBD） is an important factor in the induction of colon cancer, but its mechanism is unclear. Colitis and colitis-associated colorectal cancer （CAC） models induced using both dextran sulfate sodium （DSS） and the azoxymethane/DSS protocol were established in wild-type （WT） and CTRP4 transgenic （CTRP4-tg） C57BL6/j mice. Body weight, stool consistency and the presence of blood in the stool were analyzed; tumor quantity, size and histological characteristics were analyzed during the development of CAC. The CTRP4-tg mice exhibited significantly reduced colitis and developed far fewer macroscopic tumors; these tumors were smaller in size, and a majority of the colon tumors in these mice were restricted to the superficial mucosa. Tumors of lower grades were observed in the CTRP4-tg mice. Interleukin-6 was markedly downregulated in the CTRP4-tg mice during CAC tumorigenesis. The phosphorylation of ERK, signal transducer and activator of transcription 3 and Akt in the colon and the proliferation of intestinal epithelial cells were decreased in the CTRP4-tg mice. The injection of recombinant CTRP4 protein significantly reduced the colitis symptoms of the WT mice. CTRP4 plays an important role in inflammation and inflammation-associated colon tumorigenesis, and our research may provide a novel method for the treatment of IBD and CAC.

关键词： CAC CTRP4 DSS/AOM IBD

Total factor carbon emission performance: A Malmquist index analysis

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Total factor carbon emission performance: A Malmquist index ...

Restrictingδ-phase transformation of HC(NH2)2PbI3 via iodine-vacancy filling for efficient perovskite solar cells

国家自然科学基金委员会管理科学部宏观管理与政策学科青年基金获得者交流研讨会

作者： P.Zhou B.W.ang j.Y.Han College of Economics and Management Nanjing University of Aeronautics and Astronautics Department of Industrial and Systems Engineering National University of Singapore

This paper introduces a Malmquist CO2 emission performance index(MCPI) for measuring changes in total factor carbon emission performance over time. The MCPI is derived by solving several data envelopment analysis models. Bootstrapping MCPI is proposed to perform statistical inferences on the MCPI results. Using the index the emission performance of the world’s 18 top CO2 emitters from 1997 to2004 is studied. The results obtained show that the total factor carbon emission performance of the countries as a whole improved by 24% over the period and this was mainly driven by technological progress. The results of a cross-country regression analysis to investigate the determinants of the resulting MCPI are presented.

关键词： Carbon dioxide emissions Malmquist index Data envelopment analysis Total factor productivity Bootstrap

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Science China Materials 2020年第6期63卷 1015-1023页

作者： Yingke Ren Ning Zhang Qian W ang jun Zhu Cong Li State Key Lab of Advanced Display Technology Special Display and Imaging Technology Innovation Center of Anhui ProvinceAcademy of Opto-Electric TechnologyHefei University of TechnologyHefei 230009China College of Science Hebei University of Science and TechnologyShijiazhuang 050018China 32152 Troops Shijiazhuang 050018China School of Adv Mater and Nanotechnology Xidian UniversityXi'an 710126China

Formamidinium lead halide(α-FAPbI3)with a broad light absorption spectrum,has recently received considerable attention in optoelectronic ***,the FAI-PbI2-DMSO(DMSO:dimethyl sulfoxide)intermediate anisotropic fibers readily form a non-perovskite phase(δ-FAPbI3)and uncontrolled excess PbI2,which hinders the further increase in the efficiencies of solar *** indicate that iodine defects in polycrystalline films would enlarge the perovskite tolerance factor and result in the formation of iodide Frenkel ***,we introduce a post-treatment technique to heal the as-prepared FAPbI3 thin layer and restrain the notoriousδ-FAPbI3 through vacancy ***,a new intermediate phase of FAI-PbI2-DMSO-FACl led to a high-quality perovskite layer with an enlarged average grain size that exceeded 2μ***,the power conversion efficiencies of FAPbI3 solar cells were significantly enhanced due to the high crystallity of the pureα-phase ***,this method can be used to obtain high pure-black perovskite films and efficient solar cells.

关键词： formamidinium perovskite solar cells iodine vacancy nonperovskite phase post-treatment

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汉语与土耳其语定语类型比较与习得研究

汉语与土耳其语定语类型比较与习得研究

作者：伊培芸（Kübra DEM(?)R j(?)ang）上海师范大学

学位级别：硕士

定语是汉语学习中的一个重要的语法点。近年来,许多专家研究了汉语和韩语的定语,汉语和泰语的定语,汉语和越南语的定语,汉语和俄语的定语,汉语和英语的定语等,但是迄今为止,中国的学者鲜有对汉语和土耳其的定语进行深入系统的对比研究... 详细信息

定语是汉语学习中的一个重要的语法点。近年来,许多专家研究了汉语和韩语的定语,汉语和泰语的定语,汉语和越南语的定语,汉语和俄语的定语,汉语和英语的定语等,但是迄今为止,中国的学者鲜有对汉语和土耳其的定语进行深入系统的对比研究。随着中国“一带一路”的提出,中国和土耳其在经济、文化上的交往越来越密切,土耳其学生学汉语的热情也越来越高,到中国留学的土耳其学生也越来越多。但是由于土耳其语和汉语语言类型并不相同,土耳其语是黏着语,汉语是孤立语,土耳其语里面很少专门讲定语的,但是汉语的定语是汉语句法的一个很重要的句法成分,汉语的定语研究是汉语的语法的一个研究热点。土耳其学生在学习汉语的定语时候遇到很多困难,所以汉语和土耳其定语的比较研究非常有现实意义。本文在考察汉语与土耳其语定语基本类型基础上,运用结构主义语言学的方法进行对比分析,对土耳其语和汉语定语的结构类型及其特征进行比较分析研究。本文对下列内容进行对比分析:汉语定语的成分类型;土耳其语定语类型、土耳其语定语与汉语定语共同点与区别的对比分析。尽管土耳其语定语和汉语定语在句法、语义等方面存在不少差异,但是也有共性,比如两种语言的多项定语与中心语都遵循距离象似性原则,即越能说明中心沿所指的稳定而恒久的本质属性的词语充当定语,其位置越靠近中心语;反之,则离中心语越远。换言之,多项定语与中心语之间线性距离的远近反映了二者之间语义关系的远近。本文的最终目的就是希望把所研究的成果运用到对土耳其人学习汉语上,为中国老师教授土耳其学生提供一定借鉴,提高汉语教学的效果和质量。希望本文所得出的结论能够对土耳其学生学习汉语、教师教学和中土语言文化交流起到积极的促进作用。

关键词：土耳其语汉语定语对比分析

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PA序列Chung型对数律的极限定理

浙江大学学报（理学版） 2010年第6期37卷 625-628页

作者：傅可昂浙江工商大学数学系浙江杭州310018

设{Xn,n≥1}是一均值为零、方差有限的正相伴平稳序列.记Sn=sum Xk,Mn=maxx≤n|Sk|,n≥1 from k=1 to n,并假设01,sum Cov(X1,Xj)=O(n-α) from j=n+1 to ∞的条件下,建立了PA序列关于Chung型对数律的精确收敛速度.

关键词：正相伴序列对数律收敛速度

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轴棱锥对无衍射光束的线聚焦特性

物理学报 2013年第13期62卷 228-233页

作者：杜团结王涛吴逢铁华侨大学信息科学与工程学院福建省光传输与变换重点实验室厦门361021

基于汉克尔波理论和衍射积分理论详细分析了轴棱锥对无衍射光束的线聚焦特性,提出了一种产生周期性局域空心光束的新方法,即无衍射贝塞尔光束经过轴棱锥聚焦后产生具有塔尔博特效应的局域空心光束.数值模拟了无衍射贝塞尔光束照射轴棱锥... 详细信息

基于汉克尔波理论和衍射积分理论详细分析了轴棱锥对无衍射光束的线聚焦特性,提出了一种产生周期性局域空心光束的新方法,即无衍射贝塞尔光束经过轴棱锥聚焦后产生具有塔尔博特效应的局域空心光束.数值模拟了无衍射贝塞尔光束照射轴棱锥后,沿传输距离变化的光强分布及一个周期内光强的演变和局域空心光束的形成过程.设计实验系统,由He-Ne激光经过一套光学系统后透过轴棱锥,产生近似无衍射贝塞尔光束,再由第二个轴棱锥对产生的无衍射贝塞尔光束进行线聚焦,在第二个轴棱锥后面由显微镜观测到周期性局域空心光束,并用CCD照相机拍摄了两个周期内的光斑图,实验结果和理论分析相符合.研究结果可用于多层面微粒的操控,对周期性局域空心光束在光学微操控领域的应用具有重要的指导意义.

关键词：贝塞尔光束轴棱锥线聚焦局域空心光束

Safety and effectiveness of the SUPRACOR presbyopic LASIK algorithm on hyperopic patients

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Eye and Vision 2016年第1期3卷 253-262页

作者： Robert Edward T.ang Emerson M.Cruz Alex U.Pisig Maria Luisa Patricia C.Solis Rosalie Mae M.Reyes Gerhard Youssefi Asian Eye Institute 8th Floor PHINMA PlazaRockwell CenterMakati City 1200Philippines Department of Ophthalmology Cardinal Santos Medical Center10 Wilson St.Greenhills WestSan Juan CityPhilippines TECHNOLAS PerfectVision GmbH A Bausch&Lomb CompanyMesserschmittstrasse 1-3Munich 80992Germany

Background:To evaluate the safety and effectiveness of the Supracor excimer laser algorithm to treat hyperopic presbyopic patients using laser in-situ keratomileusis(LASIK).Methods:This is a retrospective case review of patients diagnosed with hyperopia(Sphere≥+0.0 D and presbyopia reading add≥1.0 D)who underwent Supracor excimer laser treatment on at least one eye for presbyopia correction from year May 2011 to May *** vision was further analyzed after patients were subdivided into three groups:Group A(n=22 eyes,11 patients)had Supracor on both eyes;Group B(n=18 eyes,18 patients)had Supracor in one eye and hyperopic LASIK on fellow eye;and Group C(n=29 eyes,29 patients)had Supracor in one eye and no treatment on the fellow ***:This study evaluated 58 patients wherein 69 eyes underwent Supracor presbyopic ***,mean manifest refraction spherical equivalent(MRSE)of all eyes that underwent Supracor was+1.37±0.72 D with mean uncorrected distance visual acuity(UDVA),uncorrected intermediate visual acuity(UIVA),and uncorrected near visual acuity(UNVA)of 20/50(0.35 logMAR),20/50(0.35 logMAR),and j9(0.61 logMAR),*** 6 months postoperatively,mean MRSE was−0.43±0.59 D with mean UDVA,UIVA and UNVA of 20/25(0.13 logMAR),20/20(0.01 logMAR),and j1(0.05 logMAR),*** of two lines of best-corrected distance visual acuity(BCDVA)was seen in 6%of *** corneal steepening of 1.0 D at the 3 mm zone and 0.7 D in the 5 mm zone was *** vertical coma increased from−0.02 to+0.10 while mean 4th order spherical aberration became more negative from 0.20 to−*** binocular UDVA,UIVA,and UNVA are 20/20,20/20 and j1,respectively,in all treatment groups at the 6 month postoperative *** significant differences in binocular UDVA(p≥0.36),UIVA(p≥0.19)and UNVA(p≥0.56)among groups were ***:Supracor excimer laser algorithm is safe and effective for the treatment of presbyopia in *** and bil

关键词： Presbyopia LASIK Supracor Hyperopia

A Critical Examination to the Unitarized Ij ＝ 20 ππ Scattering Chiral Amplitude

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Communications in Theoretical Physics 2001年第11期36卷 563-568页

作者： ang Qin XIAO Zhi-Guang ZHENG Han-Qing SONG Xing-Chang Department of Physics Peking UniversityBeijing 100871China Department of PhysicsPeking UniversityBeijing 100871China Department of PhysicsPeking UniversityBeijing 100871China Department of PhysicsPeking UniversityBeijing 100871China

We discuss the Padé approximation to the ππ scattering amplitudes in one-loop chiral perturbation *** approximation restores unitarity and can reproduce the correct resonance poles,but the approximation violates crossing symmetry and produces spurious poles on the complex s plane and therefore plagues its predictions in some *** we find that one virtual state in the Ij = 20 channel may have physical relevance.

关键词： ππ scattering,Padé approximation,chiral perturbation theory

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蜻蜓前后翼相位特性和气动干扰的数值研究

航空学报 2009年第7期30卷 1165-1175页

作者：肖天航昂海松南京航空航天大学航空宇航学院江苏南京210016

蜻蜓能通过改变前后翼间的相位实现对不同飞行姿态的控制。通过在动态非结构嵌套网格上求解非定常Navier-Stokes(N-S)方程,数值模拟三维蜻蜓模型在悬停(前进比j=0)和中等前飞速度(j=0.3)两种状态下的流场,每种状态各计算0°～360°间隔3... 详细信息

蜻蜓能通过改变前后翼间的相位实现对不同飞行姿态的控制。通过在动态非结构嵌套网格上求解非定常Navier-Stokes(N-S)方程,数值模拟三维蜻蜓模型在悬停(前进比j=0)和中等前飞速度(j=0.3)两种状态下的流场,每种状态各计算0°～360°间隔30°的13个不同相位。考察气动力和气动功率随相位的变化关系以及前后翼间的气动干扰。结果发现,平均举力和平均气动功率随相位的变化呈U型分布,举力足够用于平衡重力,气动功率也符合蜻蜓真实飞行的统计数据。90°～270°的较宽相位范围内,两翼间的气动干扰较为强烈且比较稳定,该范围内能量消耗较小,功率最省,在一定程度上解释了蜻蜓翼具有特定相位的现象。

关键词：蜻蜓非定常流场气动干扰相位特性数值模拟