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1例宫颈鳞癌FIGO分期ia1期的年轻患者发生广泛淋巴结转移报道

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世界核心医学期刊文摘（妇产科学分册） 2005年第10期1卷 34-34页

作者： Argenta P.A Kubicek G.j Dusenberry K.E 程金湘 Division of Gynecologic Oncology Dept. of Obstetrics and Gynecology University of Minnesota 420 Delaware Street SE Minneapolis MN 55455 United States

Background. Lymphatic and hematologic metastases are rare in microinvasive cervical cancers (FIGO stage ia1), supporting a role for conservative treatment. Cervical conization followed by prolonged surveillance is an accepted treatment in patients with low- risk features and negative surgical margins. This option is particularly appealing for younger or nulliparous patients, in whom fertility may be highly desired. Case. We report a case of a 22- year- old, HIV- negative female with stage ia1 squamous cell cervical carcinoma who was found to have bilateral lymph node metastases in both pelvic and para- aortic distributions after electing to undergo hysterectomy. Conclusion. Clinicians treating patients with microinvasive cervical cancer conservatively must be aware of the possibility of lymph node involvement and should consider radiological imaging to look for metastatic disease.

关键词：宫颈鳞癌 FIGO分期ia1 淋巴结转移宫颈鳞状细胞癌宫颈锥切子宫切除术血行转移影像学检查临床医师

添加不同剂量和来源的硒对肉鸡生产性能和硒存留率的影响

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饲料与畜牧（新饲料） 2007年第4期 50-50页

作者： I. Yoon T. M. Werner j. M. Butler 高俊(译)

用360只1日龄的肉仔鸡进行6周的试验，以评估不同的硒源和添加量对肉鸡生产性能和硒存留率的影响。在玉米豆粕型的试验日粮中添加0（负对照）、0．1、0．2、0．3ppm的酵母硒A（SelenoSource AF，Diamond V Mills，Cedar Rapids，ia），0... 详细信息

用360只1日龄的肉仔鸡进行6周的试验，以评估不同的硒源和添加量对肉鸡生产性能和硒存留率的影响。在玉米豆粕型的试验日粮中添加0（负对照）、0．1、0．2、0．3ppm的酵母硒A（SelenoSource AF，Diamond V Mills，Cedar Rapids，ia），0．3ppm的酵母硒B（Sel—Plex，Alltech，Nicholasville，KY）和0．3ppm的无机硒（来自亚硒酸钠）。用肉鸡育雏日粮饲喂至21d（每个处理6个重复，每个重复10只）。21日龄时，肉仔鸡在日粮处理内被重新分组至育肥笼中（每个处理11个重复，每个重复5只）。

关键词：肉鸡生产性能硒存留率剂量试验日粮玉米豆粕型亚硒酸钠日粮饲喂日粮处理

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外阴细胞性血管纤维瘤1例

世界核心医学期刊文摘（妇产科学分册） 2006年第3期2卷 22-22页

作者： Kerkuta R. Kennedy C.M. Benda j.A. Galask R.P. 马超 Departments of Obstetrics and Gynecology and Pathology Roy J. and Lucille A. Carver College of Medicine University of Iowa Hospitals and Clinics Iowa City IA United States Dr.

Cellular angiofibroma is a benign growth initially described in 1997, with few reports to date. A 31-year-oldwoman presented with a 3-year history of a small left labial mass, which had recently increased in size to 5 cm, and was clinically thought to be a lipoma. A simple excisionwas performed. Histologically, the mass was consistent with a cellular angiofibroma. Ten months later, the growth has not recurred. Cellular angiofibroma is a rare, benign mesenchymal lesion typically occurring on the vulva, and should be considered in the differential diagnosis of a painless, soft, vulvar mass.

关键词：血管纤维瘤细胞性阴唇间叶细胞单纯切除术鉴别诊断

一患眼肌麻痹、神经病变和帕金森综合征的家族中发现一种新的聚合酶γ突变

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世界核心医学期刊文摘（神经病学分册） 2005年第3期1卷 26-26页

作者： Mancuso M. Filosto M. Oh S.j. DiMauro S. 王英鹏 4-420 Coll. of Phys. and Surgeons 630 West 168th St New Yor k NY United States Dr.

Background: Mutations in polymerase γcause progressive external ophthalmopleg ia and a variety of associated symptoms and signs, including neuropathy, ataxia, hypogonadism, hearing loss, muscle weakness, and psychiatric problems. Extrapyr amidal signs have been rarely described. Objective: To describe a family with a novel polymerase γ.mutation and autosomal dominant transmission of progressive external ophthalmoplegia, neuropathy, hypogonadism, and parkinsonism. Design: Ca se report. Patients: The proband, a 49 year old woman with incipient parkinson ism, and her 59 year old brother with overt parkinsonian features. Main Outcom e Measures: Mutation in the proband by sequencing the polymerase γ.gene and in affected relatives by restriction fragment length polymorphism analysis. Results : We found multiple mitochondrial DNA deletions in the probands muscle and a n ovel missense mutation in the polymerase γ.gene (A2492G) in the proband and in her affected siblings. Conclusion: Parkinsonism was a prominent clinical feature in this family with autosomal dominant ophthalmoplegia, multiple mitochondrial DNA deletions, and a novel mutation in the polymerase γgene.

关键词：帕金森综合征眼肌麻痹聚合酶锥体外系体征先证者性腺功能减退早期帕金森基因突变共济失调 DNA

ia型遗传性运动感觉神经病的临床严重程度和轴突功能障碍

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世界核心医学期刊文摘（神经病学分册） 2005年第6期1卷 30-30页

作者： Verhamme C. Van Schaik I.N. Koelman j.H.T.M. 袁海峰 Dept. Neurol. Clin. Neurophysiol. Academic Medical Centre University of Amsterdam PO Box 22700 1100 DE Amsterdam Netherlands

Background: Hereditary motor and sensory neuropathy type ia (HMSN ia) is known as a primarily demyelinating peripheral nerve disease. Evidence is accumulating that axonal involvement determines the course of the disease process. Methods: Fifty- one patients were investigated. Physical disability and impairments were scored. Nerve conduction velocities (NCVs) were used as indirect measures for myelination status and compound muscle/sensory nerve action potential (CMAP/SNAP) amplitudes served as indirect measures for axonal function. Results: Median age was 39 years (range 6- 69). Muscle weakness and sensory dysfunction was more severe in the legs than in the arms and distally more than proximally. However, more than 40 % of the patients had proximal muscle weakness in the legs. Three point grip was used as representative of combined distal arm muscle groups. CMAP amplitude was the most important independent variable in a multiple linear regression model (forward selection) to explain the relation between three point grip strength and four different features, i. e., CMAP amplitude of the abductor pollicis brevis, median nerve MNCV, gender, and duration of signs and symptoms. The severity of axonal dysfunction was nerve length- dependent and was related to the myelination status. The mild physical disability due to both muscle weakness and sensory dysfunction was also related to axonal dysfunction. Conclusions: In HMSN ia, clinical disease severity at the impairment and disability levels is related to the severity of axonal dysfunction. Our data support the hypothesis that the myelination status is one of the factors that determine the extent of axonal dysfunction later in life. Proximal weakness of the legs is encountered in a considerable proportion of our patients.

关键词：运动感觉 ia 临床严重程度功能障碍下肢近端肌神经传导速度正中神经肌无力髓鞘复合动作电位

疑似阿尔茨海默病患者不自觉认知功能缺陷(认知功能病感失认)的对照研究

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世界核心医学期刊文摘（神经病学分册） 2005年第7期1卷 50-50页

作者： Barrett A.M. Eslinger P.j. Ballentine N.H. Heilman K.M. 邓剑平 Kess ler Med. Rehab. Res./Educ. Corp. 1199 Pleasant Valley Way West Orange NJ 07052 United States Dr.

Objective: To develop a quantitative method of assessing cognitive anosognosia in six cognitive and two noncognitive ***: Control (n =32) and prob able Alzheimer disease(pAD) (n = 14) subjects self-estimated memory, attention, generative behavior, naming, visuospatial skill, limb praxis, mood,and uncorrec ted vision, both before and after these abilities were assessed. Based on this e stimate and their performance the authors calculated an anosognosia ratio (AR) b y dividing the difference between estimated and actual performance by an estimat ed and actual performance sum. With perfect awareness,AR = 0. Overestimating abi lities would yield a positive AR (≤1); underestimation would yield a negative A R (≥-1). Results: Relative to controls, pAD subjects demonstrated anosognosia. Pre-testing (off-line), pAD subjects overestimated their visuospatial skill; p ost-testing (on-line), pAD subjects overestimated their memory. Control subjec ts also made selfrating errors, underestimating their attention pre-testing and overestimating limb praxis and vision post-testing. Conclusions:This anosognos ia assessment method may allow more detailed examination of distorted self-awar eness. These results suggest that screening for anosognosia in probable Alzheime r disease (pAD) should include self-estimates of visuospatial function, and tha t, in pAD, it may be useful to assess anosognosia for amnesia both before and af ter memory testing.

关键词：认知功能阿尔茨海默病失认病感记忆测试视觉空间过高估计矫正视力不自觉自我评价

先天性ia型糖基化障碍患者的骨骼发育不良和脊髓病

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世界核心医学期刊文摘（儿科学分册） 2006年第5期2卷 31-31页

作者： Schade Van Westrum S.M. Nederkoorn P.j. Schuurman P.R. B.T. Poll- The 贺莉 Department of Pediatrics University of Amsterdam Academic Medical Center PO Box 22660 1100 DD Amsterdam Netherlands.Dr

We report on a boy with a congenital disorder of glycosylation (CDG) ia and a severe narrowing of the spinal canal caused by atlantoaxial subluxation with anterior displacement of C1. C1-laminectomy improved the progressive paresis. Progressive paresis caused by spinal cord compression is a hitherto unrecognized complication in patients with CDG-ia.

关键词：骨骼发育不良脊髓病寰枢椎半脱位脊髓受压进行性先天性Ⅰa型糖基化障碍

桡骨远端关节内骨折的舟月骨间韧带、月三角骨间韧带及TFCC损伤:MDCT关节造影评估患病率

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国际医学放射学杂志 2016年第3期 323-323页

作者： A.Klempka M.Wagner S.Fodor K.j.Prommersberger M.Uder R.Schmitt 郑丽娟 Department of Diagnostic and Interventional Radiology Cardiovascular Center Bad Neustadt an der Saale

摘要目的评估在桡骨远端关节内骨折(ia DRF)中,舟月骨间韧带(SLIL)、月三角骨间韧带(LTIL)及三角纤维软骨复合体(TFCC)损伤的患病率。方法本研究共纳入233例急性ia DRF病人并接受MDCT关节造影检查。将SLIL及LTIL损伤分为正常、部分断裂... 详细信息

摘要目的评估在桡骨远端关节内骨折(ia DRF)中,舟月骨间韧带(SLIL)、月三角骨间韧带(LTIL)及三角纤维软骨复合体(TFCC)损伤的患病率。方法本研究共纳入233例急性ia DRF病人并接受MDCT关节造影检查。将SLIL及LTIL损伤分为正常、部分断裂及完全断裂。SLIL的重度损伤定义为背侧段的完全断裂,LTIL的重度损伤定义为掌侧段的完全

关键词：桡骨远端关节内骨折 TFCC 骨间韧带关节造影患病率 MDCT

动脉瘤所致蛛网膜下腔出血后脑血管痉挛治疗的系统性回顾与meta分析

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国际医学放射学杂志 2017年第5期 616-616页

作者： G.Boulouis M.A.Labeyrie j.Raymond C.Rodriguez-Régent A.C.Lukaszewicz D.Bresson 华蓓 INSERM U894 CH Sainte-AnneDepartment of NeuroradiologyUniversité Paris-Descartes

摘要目的采用meta分析评估动脉瘤所致蛛网膜下腔出血(a SAH)出现脑血管痉挛(CVS)并采用靶向治疗病人的临床预后,以及评估严重/难治性血管痉挛病人动脉内(ia)

关键词：难治性 CVS 动脉瘤末次随访血管痉挛