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The Oral Health Status of Person w.th Special Needs in Kumasi

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Open j.urnal of Stomatology 2024年第1期14卷 14-31页

作者： Ama Agyeibea Amuasi Alexander Oti-Acheampong Victoria N. A. Boadu lord j. j. Gow.ns The Department Child Oral Health & Orthodontics School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana The Department of Oral & Maxillofacial Sciences School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana The Department of Community Dentistry School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana

Background: The most prevalent non-communicable disease w.rldw.de is oral health-related disease, w.th dental caries and periodontal conditions being common. Oral health status significantly impacts overall health and quality of life. Barriers to dental care affect children w.th special needs. This study evaluates the oral health status and treatment requirements of people w.th special needs. Methodology: This descriptive cross-sectional study in Kumasi, Ghana examined oral health status among people, 121 children w.th special needs over tw. months, in j.ne-j.ly 2022. Dental caries, periodontal changes, malocclusion, and trauma w.re assessed. The data w.s analyzed using SPSS 20.0. Results: The oral health status among people w.th special needs in this study w.s generally moderate, w.th a range from very good to very poor. The prevalence of dental caries w.s 37%, w.th a mean DMFT score of 2.82. Periodontal health show.d unsatisfactory indicators such as mobile teeth, poor gingival health, high plaque scores, and the presence of halitosis. Conclusion: This descriptive study aimed to provide baseline data on the oral health status of special needs students in Kumasi, addressing the lack of know.edge in this area. It highlighted the importance of dental care in maintaining good oral health and overall w.ll-being in individuals w.th special needs. Coordinated efforts by dental professionals are needed to provide dental health education and preventive interventions for these children.

关键词： Special Needs Oral Health Dental Caries Periodontal Diseases Malocclusion

The Oral Health Status of Person w.th Special Needs in Kumasi

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Fully integrated approach： an alternative solution of coupling a GIS and diffuse pollution models

Open j.urnal of Stomatology（口腔学期刊） 2024年第1期

作者： Ama Agyeibea Amuasi Alexander Oti-Acheampong Victoria N. A. Boadu lord j. j. Gow.ns

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Frontiers of Environmental Science & Engineering 2014年第4期8卷 616-623页

作者： S. LIU R.E. BRAZIER A. L. HEATHw.ITE w. LIU School of Environment Tsinghua University Beijing 100084 China Department of Geography University of Exeter EX4 4R J Exeter UK Centre for Sustainable w.ter Management The Lancaster Environment Centre Lancaster University Lancaster LA1 4YQ UK

As a tool for management, query, visualization and analysis of spatially referred information, GIS has been recognized as a method to aid the modeling of diffuse pollution and visualize the results in a spatial context. A common question in integrating diffuse pollution models and GIS is to choose a suitable coupling approach, in w.ich the feature of diffuse pollution models should be taken into account. In this paper, w. report on our experience in coupling a distributed diffuse pollution model w.th a GIS. A prototype of fully integrated system is developed in this paper. This system has high flexibility, extendibility and great data management efficiency. Differences in applicability of loose coupling, tight coupling and fully integrated approaches are addressed. It is concluded that the fully integrated approach can avoid tanglesome data exchange and routine execution and more robust than loose and tight coupling approaches and is suitable for distributed diffuse pollution modes.

关键词： diffuse pollution GIS modeling nutrients phosphorus

MicroRNA profile in neosquamous esophageal mucosa follow.ng ablation of Barrett's esophagus

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w.rld j.urnal of Gastroenterology 2017年第30期23卷 5508-5518页

作者： Loveena Sreedharan George C Mayne David I w.tson Timothy Bright Reginald V lord Alfiya Ansar Tingting w.ng j.kob Kist David Stj.Astill Damian j.Hussey Department of Surgery Flinders Medical Centre Flinders University St Vincent’s Centre for Applied Medical Research Department of Anatomical Pathology Flinders Medical Centre

To investigate the microRNA expression profile in esophageal neosquamous epithelium from patients w.o had undergone ablation of Barrett’s esophagus. METHODSHigh throughput screening using TaqMan® Array Human MicroRNA quantitative PCR w.s used to determine expression levels of 754 microRNAs in distal esophageal mucosa (1 cm above the gastro-esophageal j.nction) from 16 patients w.o had undergone ablation of non-dysplastic Barrett’s esophagus using argon plasma coagulation vs pretreatment mucosa, post-treatment proximal normal non-treated esophageal mucosa, and esophageal mucosal biopsies from 10 controls w.thout Barrett’s esophagus. Biopsies of squamous mucosa w.re also taken from 5 cm above the pre-ablation squamo-columnar j.nction. Predicted mRNA target pathw.y analysis w.s used to investigate the functional involvement of differentially expressed microRNAs. RESULTSForty-four microRNAs w.re differentially expressed betw.en control squamous mucosa vs post-ablation neosquamous mucosa. Nineteen microRNAs w.re differentially expressed betw.en post-ablation neosquamous and post-ablation squamous mucosa obtained from the more proximal non-treated esophageal segment. Tw.lve microRNAs w.re differentially expressed in both neosquamous vs matched proximal squamous mucosa and neosquamous vs squamous mucosa from healthy patients. Nine microRNAs (miR-424-5p, miR-127-3p, miR-98-5p, miR-187-3p, miR-495-3p, miR-34c-5p, miR-223-5p, miR-539-5p, miR-376a-3p, miR-409-3p) w.re expressed at higher levels in post-ablation neosquamous mucosa than in matched proximal squamous and healthy squamous mucosa. These microRNAs w.re also more highly expressed in Barrett’s esophagus mucosa than matched proximal squamous and squamous mucosa from controls. Target prediction and pathw.y analysis suggests that these microRNAs may be involved in the regulation of cell survival signalling pathw.ys. Three microRNAs (miR-187-3p, miR-135b-5p and miR-31-5p) w.re expressed at higher levels in post-

关键词： Neosquamous Barrett’s esophagus Ablation

Integrated lipidomics and proteomics netw.rk analysis highlights lipid and immunity pathw.ys associated w.th Alzheimer's disease

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Translational Neurodegeneration 2020年第3期9卷 458-472页

作者： j.n Xu Giulia Bankov Min Kim Asger w.etlind j.die lord Rebecca Green Angela Hodges Abdul Hye Dag Aarsland Latha Velayudhan Richard j.B.Dobson Petroula Proitsi Cristina Legido-Quigley on behalf of the AddNeuroMed Consortium Institute of Pharmaceutical Science King's College LondonLondonUK. Institute of Psychiatry Psychology&NeuroscienceKing's College LondonLondonUK. Steno Diabetes Center Copenhagen GentofteDenmark Center for Age Related Medicine Stavanger University HospitalStavangerNorway 不详

Background:There is an urgent need to understand the pathw.ys and processes underlying Alzheimer's disease(AD)for early diagnosis and development of effective *** study w.s aimed to investigate Alzheimer's dementia using an unsupervised lipid,protein and gene multi-omics integrative ***:A lipidomics dataset comprising 185 AD patients,40 mild cognitive impairment(MCI)individuals and 185 controls,and tw. proteomics datasets(295 AD,159 MCI and 197 controls)w.re used for w.ighted gene CO-expression netw.rk analyses(w.CNA).Correlations of modules created w.thin each modality w.th clinical AD diagnosis,brain atrophy measures and disease progression,as w.ll as their correlations w.th each other,w.re *** ontology enrichment analysis w.s employed to examine the biological processes and molecular and cellular functions of protein modules associated w.th AD *** species w.re annotated in the lipid modules associated w.th AD *** associations betw.en established AD risk loci and the lipid/protein modules that show.d high correlation w.th AD phenotypes w.re also ***:Five of the 20 identified lipid modules and five of the 17 identified protein modules w.re correlated w.th clinical AD diagnosis,brain atrophy measures and disease *** lipid modules comprising phospholipids,triglycerides,sphingolipids and cholesterol esters w.re correlated w.th AD risk loci involved in immune response and lipid *** five protein modules involved in positive regulation of cytokine production,neutrophil-mediated immunity,and humoral immune responses w.re correlated w.th AD risk loci involved in immune and complement systems and in lipid metabolism(the APOE ε4 genotype).Conclusions:Modules of tightly regulated lipids and proteins,drivers in lipid homeostasis and innate immunity,are strongly associated w.th AD phenotypes.

关键词： Alzheimer's disease Dementia Brain atrophy sMRI Rate of cognitive decline Lipidomics Proteomics AD risk loci w.CNA

High pressure and temperature phase stabilities of dolomite and ankerite

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High pressure and temperature phase stabilities of dolomite ...

电离辐射诱发小鼠骨髓细胞依赖和不依赖P53基因的凋亡

第八届“从原子到地球”——高压科学与地球科学研讨会

作者： Fei Qin Oliver T.lord j.mes w.E.Drew.tt David Edw.rds Michael j.w.lter School of Earth Sciences and Resources China University of Geosciences (Beijing) School of Earth Sciences University of Bristol Geophysical Laboratory Carnegie Institute for Science

The fate of subducted carbonate has profound implications for the global carbon cycle and great importance for the geodynamic and geochemical evolution of Earth‘s deep interior. Understanding the structural evolution and stability of key carbonate phases is thus important for understanding the carbon cycleand redox conditions in the mantle1-3. Dolomite (Ca,Mg)(CO), is thought to constitute up to 0% of the Earth‘s accessible carbonate reserviors4. Since there is evidence of dolomite inclusions in ultra-deep diamonds, new.high pressure-temperature polymorphs of dolomite could be crucial carbon-containing phases in the Earth‘s mantle5-8.

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科学通报 1996年第16期41卷 1509-1512页

作者：崔玉芳周平坤 B.I.lord j.H.Hendry 军事医学科学院放射医学研究所北京100850 Paterson Institute for Cancer Research ManchesterUK

细胞凋亡(apoptosis)或程序性细胞死亡(programmed cell death),是一种具有典型形态学和生化特征的细胞死亡模式。在胚胎发育,T,B细胞成熟和内分泌相关的组织萎缩等生命过程中发生的细胞死亡,就是一种生理性细胞凋亡,以此控制体内细胞... 详细信息

细胞凋亡(apoptosis)或程序性细胞死亡(programmed cell death),是一种具有典型形态学和生化特征的细胞死亡模式。在胚胎发育,T,B细胞成熟和内分泌相关的组织萎缩等生命过程中发生的细胞死亡,就是一种生理性细胞凋亡,以此控制体内细胞数量。辐射和某些抗肿瘤药物等DNA损伤因子,亦能诱发细胞凋亡,并与某些肿瘤相关基因的诱导表达和蛋白稳定性的改变等事件发生相关。P53基因是一种抑癌基因,参与细胞增殖调控,使细胞生长停滞于G_1期。近年发现,P53基因在细胞DNA受损伤后引发的细胞凋亡过程中也起重要作用。不同学者分别报道,电离辐射诱发小鼠胸腺细胞和小肠上皮细胞的凋亡,是依赖于P53基因,包括P53基因表达增加和P53蛋白稳定性增强。在P53基因缺失纯合子小鼠中,电离辐射就不能有效地启动上述组织细胞的凋亡机制。本文利用基因打靶技术产生的P53基因突变小鼠模型,研究不同P53基因状态下,即野生型(P53+/+)、杂合子(P53+/-)和纯合子突变型(P53-/-),电离辐射诱发小鼠骨髓细胞的凋亡。

关键词：细胞凋亡骨髓细胞电离辐射抑癌基因 P53基因

The Civil court practice 2009 /

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2009年

作者： editor-in-chief lord Neuberger of Abbotsbury consulting editor lord j.stice Hooper general editors P.K.j. Thompson Louise di Mambro.

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香根鸢尾

人与自然 2013年第4期 48-53页

作者：子皿 lord.V Andiw.lfe j.man

它的根茎价比黄金。从鸢尾花根提炼出的精油是香水的重要原料，只需添加一点点，就可以完全改变香水本来的味道，使其更加迷人。

关键词：鸢尾花香根香水精油