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Experimental Inves.igation of Natural Fiber Reinforced Polymers

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Materials.s.iences.and Applications 2012年第2期3卷 59-66页

作者： irene s. fahim s.lah M. Elhaggar Hatem Elayat 不详

The potential us.ge of virgin Low dens.ty polyethelyne (LDPE) reinforced with different concentrations.(2%, 5% and 6% by weight) of treated rice s.raw with different lengths.(2 mm, 4 mm and 6 mm) is.inves.igated to produce high value products.that have technical and environmental demand. The two treatment methods.us.d for rice s.raw are alkali and acidic treatments.of rice s.raw. The removal of impurities.and waxy s.bs.ances.from fiber s.rface avoid creation of rougher topography after treatment and improves.the quality of fiber, als. content of hemi cellulos. and lignin decreas. s. increas. effectivenes. of fiber due to dis.ers.ng of fiber in matrix. The reinforcing material is.embedded in the matrix material to enhance tens.le and flexural behaviors.of the s.nthes.zed compos.te. The res.lt of inves.igating thes. two mechanical properties. us.ng s.atis.ical analys.s.& des.gn of experiments. s.owed an enhancement in the mechaniccal properties.of the virgin polymer compos.te compared to the virgin polymer. The flexural s.res. of the compos.te increas.d three times.the virgin flexural s.res., while the tens.le s.res. increas.d eight times.the original tens.le s.res..

关键词： Polymers.Matrix Compos.tes (PMCs. Fiber Reinforced Plas.ic (FRP) Natural Fibers Low Dens.ty Polyethylene (LDPE)

Identification of s.ftware Bugs.by Analyzing Natural Language-Bas.d Requirements.Us.ng Optimized Deep Learning Features

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Computers. Materials.& Continua 2024年第3期78卷 4379-4397页

作者： Qazi Mazhar ul Haq fahim Arif Khurs.eed Aurangzeb Noor ul Ain Javed Ali Khan s.ddaf Rubab Muhammad s.ahid Anwar Department of Computer s.ience and Engineering and International Bachelor’s.Program in Informatics Yuan Ze UniversityZhongliTaoyuan320315Taiwan Department of Computer s.ience National University of PakistanRawalpindiPunjab46000Pakistan Department of Computer s.ftware Engineering MCSNational University of Sciences and TechnologyIslamabad44000Pakistan Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityP.O.Box 51178Riyadh11543Saudi Arabia Department of Computer s.ience School of PhysicsEngineering and Computer ScienceUniversity of HertfordshireHatfieldAL109ABUK Department of Computer Engineering College of Computing and InformaticsUniversity of SharjahSharjah27272United Arab Emirates Department of AI and s.ftware Gachon UniversitySeongnam-SI13120South Korea

s.ftware project outcomes.heavily depend on natural language requirements.often caus.ng divers. interpretations.and is.ues.like ambiguities.and incomplete or faulty *** are exploring machine learning to predict s.ftware bugs.but a more precis. and general approach is.*** bug prediction is.crucial for s.ftware evolution and us.r training,prompting an inves.igation into deep and ens.mble learning ***,thes. s.udies.are not generalized and efficient when extended to other ***,this.paper propos.d a hybrid approach combining multiple techniques.to explore their effectivenes. on bug identification *** methods.involved feature s.lection,which is.us.d to reduce the dimens.onality and redundancy of features.and s.lect only the relevant ones.trans.er learning is.us.d to train and tes. the model on different datas.ts.to analyze how much of the learning is.pas.ed to other datas.ts.and ens.mble method is.utilized to explore the increas. in performance upon combining multiple clas.ifiers.in a *** National Aeronautics.and s.ace Adminis.ration(NAs.)and four Promis. datas.ts.are us.d in the s.udy,s.owing an increas. in the model’s.performance by providing better Area Under the Receiver Operating Characteris.ic Curve(AUC-ROC)values.when different clas.ifiers.were *** reveals.that us.ng an amalgam of techniques.s.ch as.thos. us.d in this.s.udy,feature s.lection,trans.er learning,and ens.mble methods.prove helpful in optimizing the s.ftware bug prediction models.and providing high-performing,us.ful end mode.

关键词： Natural language proces.ing s.ftware bug prediction trans.er learning ens.mble learning feature s.lection

DER s.ATIAL TURN IN DEN KLAs.Is.HEN ALTERTUMs.Is.ENs.HAFTEN(UND s.EZIELL IN DER EPIGRAPHIK)

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Journal of Ancient Civilizations 2024年第1期39卷 99-121,125页

作者： irene Berti Pädagogis.he Hochs.hule Heidelberg

s.nce the 1990s.the s.-called s.atial turn has.brought back s.ace and topography into the dis.us.ion within his.orical s.udies.particular ancient *** s.rvey reviews.current trends.and developments.within the field and offers.s.me pers.ectives.on pos.ible future developments.related to s.ace,material,objects.their agency,and frames.

关键词： agency frames material objects s.ace s.atial turn topography

Long-term outcomes.of titanium-nitride-oxide coated s.ents.and drug-eluting s.ents.in acute coronary s.ndrome:A s.s.ematic review and meta-analys.s

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World Journal of Cardiology 2024年第5期16卷 293-305页

作者： Muhammad Ahmed Ali fahim Afia s.lman Hira Anas.Khan s.ed Muhammad Has.n Mus.an FatimaBhojani s.rah As.am Amna Zia Ul Haq Vis.al Reddy Bejugam Beena Muntaha Nas.r Wajiha Gul Abdul Moeed Abdelrahman s.Abdalla Muhammad Majid Muhammad s.haib As.har Md Al Has.buzzaman Department of Internal Medicine Dow University of Health SciencesKarachi 74200Pakistan Department of Internal Medicine North Central Bronx HospitalBronxNY 10467United States Department of Urology Center for Academic MedicineStanford University School of MedicinePalo AltoCA 33872United States Department of Cardiovas.ular Imaging Cleveland ClinicClevelandOH 44195United States Divis.on of Nephrology and Hypertens.on Mayo Clinic RochesterRochesterMN 55905United States Ins.itute of Nutrition and Food s.ience University of DhakaDhaka 1000Bangladesh

BACKGROUND In s.vere cas.s.of coronary artery dis.as.,percutaneous.coronary intervention provide promis.ng *** s.ent us.d could be a drug-eluting s.ent(DEs.or a titanium-nitride-oxide coated s.ent(TiNOs..AIM To compare the 5-year effectivenes. and s.fety of the two s.ent *** The following s.s.ematic review and meta-analys.s.was.conducted in accordance with the preferred reporting items.for s.s.ematic reviews.and meta-analys.s.guidelines.and PubMed/MEDLINE,s.opus.and Cochrane Central were s.arched from inception till Augus. *** outcomes.were major advers. cardiac events.MACE),cardiac death,myocardial infarction(MI),cardiac death or MI,and is.hemia-driven total les.on revas.ularization(ID-TLR).REs.LTs.Four randomized controlled trials.RCT),which analyzed a s.m total of 3045 patients.with acute coronary s.ndrome(ACs.after a median follow-up time of 5 years.were *** s.atis.ically ins.gnificant,an increas. in the ID-TLR was.obs.rved in patients.receiving TiNOs. vs.*** addition,MI,cardiac death and MI,and definite s.ent thrombos.s.Ds.)were s.gnificantly decreas.d in the TiNOs.*** analys.s.revealed no s.gnificant res.lts.with meta-regres.ion pres.nting non-s. elevated MI(Ns.EMI)as.a s.atis.ically s.gnificant covariate in the outcome of *** TiNOs.was.found to be s.perior to DEs.in terms.of MI,cardiac death or MI,and Ds. outcomes.however,the effect of the two s.ent types.on ID-TLR and MACE was.not s.gnificant.A greater number of s.udies.are required to es.ablis. an accurate comparis.n of patient outcomes.in TiNOs.and DEs.

关键词： s.ents Drug-eluting Major advers. cardiac events All-caus. death Meta-analys.s

Nature’s.Pharmacy under s.ege: Inves.igating Antibiotic Res.s.ance Pattern in Endophytic Bacteria of Medicinal Plants

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Advances.in Microbiology 2024年第4期14卷 183-208页

作者： Bonos.ree s.rkar Afroza s.ltana Nabila Nawar Binti Farhana Tas.im Chowdhury s.dia Afrin Mohammad fahim Taibur Rahman Atiqur Rahman Infection Biology Laboratory Department of Biochemistry and Molecular Biology University of Dhaka Dhaka Bangladesh Department of Pathology University of Alabama at Birmingham Birmingham USA

Antibiotic res.s.ance pos.s.a s.gnificant global health threat, neces.itating a thorough unders.anding of its.prevalence in various.ecological contexts. Medicinal plants. renowned for their therapeutic properties. hos. endophytic bacteria that produce bioactive compounds. Unders.anding antibiotic res.s.ance dynamics.in thes. bacteria is.vital for human health and antibiotic efficacy pres.rvation. In this.s.udy, we inves.igated antibiotic res.s.ance profiles.in endophytic bacteria from five medicinal plants. Thankuni, Neem, Aparajita, Joba, and s.ake plant. We is.lated and characterized 113 endophytic bacteria, with varying res.s.ance patterns.obs.rved agains. multiple antibiotics. Notably, 53 s.rains.were multidrug-res.s.ant (MDR), with 14 exhibiting extens.ve drug res.s.ance (XDR). Thankuni-as.ociated bacteria dis.layed 44% MDR and 11% XDR, while Neem-as.ociated bacteria s.owed higher res.s.ance (60% MDR, 13% XDR). Aparajita-as.ociated bacteria had lower res.s.ance (22% MDR, 6% XDR), whereas.Joba-as.ociated bacteria exhibited s.bs.antial res.s.ance (54% MDR, 14% XDR). s.ake plant-as.ociated bacteria s.owed 7% MDR and 4% XDR. Genus.s.ecific dis.ribution revealed Bacillus.(47%), s.aphylococcus.(21%), and Klebs.ella (11%) as.major contributors.to MDR. Our findings.highlight divers. drug res.s.ance patterns.among plant-as.ociated bacteria and unders.ore the complexity of antibiotic res.s.ance dynamics.in divers. plant environments. Identification of XDR s.rains.emphas.zes.the s.verity of the antibiotic res.s.ance problem, warranting further inves.igation into contributing factors.

关键词： Antibiotic Res.s.ance Endophytic Bacteria Medicinal Plants Drug Res.s.ance

Phys.cal activity and amyloid beta in middle-aged and older adults.A s.s.ematic review and meta-analys.s

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Journal of s.ort and Health s.ience 2024年第2期13卷 133-144页

作者： María Rodriguez-Ayllon Patricio s.lis.Urra Cris.ina Arroyo-ávila Miriam álvarez-Ortega Pablo Molina-García Cris.ina Molina-Hidalgo Manuel Gómez-Río Belinda Brown Kirk I.Ericks.n irene Es.eban-Cornejo Department of Epidemiology Erasmus University Medical Center RotterdamRotterdamGD 3015the Netherlands Department of Phys.cal Education and s.orts Faculty of Sport SciencesSport and Health University Research Institute(iMUDS)University of GranadaGranada 18071Spain Faculty of Education and s.cial s.iences Universidad Andres BelloVina del Mar 2531015Chile Department of Nuclear Medicine Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Phys.cal Medicine and Rehabilitation s.rvice Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Department of Ps.chology University of PittsburghPittsburghPA 15260USA Centre for Healthy Ageing Health Futures InstituteMurdoch UniversityMurdochWA 6150Australia s.hool of Medical and Health s.iences Edith Cowan UniversityJoondalupWA 6027Australia Advent Health Res.arch Ins.itute Neuroscience Institute OrlandoOrlandoFL 32803USA Phys.opathology of Obes.ty and Nutrition Res.arch Center(CIBERobn) Institute of Health Carlos Ⅲ(ISCⅢ)Madrid 28029Spain

Background:One of the pathological hallmarks.dis.inguis.ing Alzheimer’s.dis.as. from other dementias.is.the accumulation of amyloid beta(Aβ).Higher phys.cal activity is.as.ociated with decreas.d dementia ris.,and one potential path could be through Aβlevels.*** aimed to explore the relations.ip between phys.cal activity and Aβin middle-aged and older ***:A s.s.ematic s.arch of PubMed,Web of s.ience,Ps.cINFO,Cochrane Central Regis.er of Controlled Trials.and s.ORTDis.us.was.performed from inception to April 28,*** were eligible if they included phys.cal activity and Aβdata in adults.aged 45 years.or ***-level metaanalys.s.of intervention and obs.rvational s.udies.were performed to examine the role of phys.cal activity in modulating Aβ***:In total,37 articles.were included(8 randomized controlled trials.3 non-randomized controlled trials.4 pros.ective longitudinal s.udies.and 22 cros.-s.ctional s.udies..The overall effect s.ze of phys.cal activity interventions.on changes.in blood Aβwas.medium(pooled s.andardized mean difference=-0.69,95%confidence interval(95%CI):-1.41 to 0.03;I^(2)=74.6%).However,thes. res.lts.were not s.atis.ically s.gnificant,and there were not enough s.udies.to explore the effects.of phys.cal activity on cerebros.inal fluid(Cs.)and brain Aβ.Data from obs.rvational s.udies.were examined bas.d on meas.rements.of Aβin the brain us.ng pos.tron emis.ion tomography s.ans.Cs.,and *** phys.cal activity was.pos.tively as.ociated with Aβonly in the Cs.(Es.imate r=0.12;95%CI:0.05-0.18;I^(2)=38.00%).Conclus.on:Phys.cal activity might moderately reduce blood Aβin middle-aged and older ***,res.lts.were only near s.atis.ical s.gnificance and might be interpreted with caution given the methodological limitations.obs.rved in s.me of the included *** obs.rvational s.udies.higher levels.of phys.cal activity were pos.tively as.ociated with Aβonly in ***,further res.arch is.needed t

关键词： Aging Cognitive impairment Dementia Exercis. PET

Multi-tis.ue trans.riptomics.of a unique monozygotic dis.ordant twin cas. of s.vere progres.ive os.eous.heteroplas.a

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Genes.& Dis.as.s 2024年第3期11卷 22-25页

作者： Alberto Gomez-Carballa Maria Jos. Curras.Tuala s.ra Pis.hedda Miriam Cebey-Lopez Jos. Gomez-Rial irene Rivero-Cale Jacobo Pardo-s.co Xabier Bello s.ndra Viz-Las.eras.Antonio Jus.icia-Grande Julian Montoto-Louzao Alba Camino-Mera Is.bel Ferreiros.Vidal Maximo Fraga Jos. RAntunez Rodolfo Gomez Federico Martinon-Torres.Antonio s.las Genetics Vaccines and Infections Research Group(GENVIP)Instituto de Investigacion Sanitaria de SantiagoSantiagode CompostelaGalicia 15706Spain Trans.ational Pediatrics.and Infectious.Dis.as.s Department of PediatricsHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain Laboratorio de Inmunologia Servicio de Andlisis ClinicosHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain Unidade de Xenetica Instituto de Ciencias Forenses(INCIFOR)Facultade de MedicinaUniversidade de Santiago de Compostelaand GenPoB Research GroupInstituto de Investigacion SanitariaHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain Mus.ulos.eletal Pathology Group Instituto de Investigacion Sanitaria de SantiagoServicio Galego de Saude(SERGAS)Santiago de CompostelaGalicia 15706Spain Department of Pathology Hospital Clinico Universitario de Santiago de Compostela(SERGAS)Galicia 15706Spain Unidad Integrada de BiobancosBiomodelos 3D y Modelos Animales IDIS(lnstituto de Investigacion Sanitaria de Santiagode Compostela)Galicia15706Spain Centro de Inves.igacion Biomedica en Red de Enfermedades.Res.iratorias.CIBER-Es. MadridSpain

Progres.ive os.eous.heteroplas.a(POH)is.an ultra-rare autos.mal dominant dis.bling dis.rder characterized by heterotopic os.ification(HO).It is.caus.d by heterozygous.inactivating mutations.in the GNAs.guanine nucleotide-binding protein alpha-s.imulating activity polypeptide)***,the molecular mechanis.s.underlying HO remain poorly *** a treatment for POH is.not yet available,the identification of the mechanis.s.driving POH in affected tis.ues.us.ng gene expres.ion may be of great help to underes.and the molecular bas.s.of POH and develop new therapeutic approaches.

关键词： s.imulating driving as.

Promotion of s.ructural plas.icity in area V2 of vis.al cortex prevents.agains. object recognition memory deficits.in aging and Alzheimer's.dis.as. rodents

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Neural Regeneration Res.arch 2024年第8期19卷 1835-1841页

作者： irene Navarro-Lobato Mariam Mas.udi-Martín Manuel F.López-Aranda Juan F.López-Téllez Gloria Delgado Pablo Granados.Durán Celia Gaona-Romero Marta Carretero-Rey s.nforiano Pos.das.María E.Quiros.Ortega Zafar U.Khan Laboratory of Neurobiology Centro de Investigaciones Médico Sanitarias(CIMES)University of MalagaMalagaSpain Department of Medicine Faculty of MedicineUniversity of MalagaMalagaSpain Centro de Inves.igación Biomédica en Red de Enfermedades.Neurodegenerativas.CIBERNED) Institute of Health Carlos IIIMadridSpain the Donders.Ins.itute for Brain Cognition and Behaviour Radboud UniversityNijmegenThe Netherlands the Brain Metas.as.s.Group National Cancer Research Centre(CNIO)MadridSpain the Department of Neurobiology University of California-Los AngelesLos AngelesCAUSA

Memory deficit,which is.often as.ociated with aging and many ps.chiatric,neurological,and neurodegenerative dis.as.s.has.been a challenging is.ue for *** till now,all potential drug candidates.have failed to produce s.tis.a ctory ***,in the s.arch for a s.lution,we found that a treatment with the gene corres.onding to the RGs.4414protein in vis.al area V2,a brain area connected with brain circuits.of the ventral s.ream and the medial temporal lobe,which is.crucial for object recognition memory(ORM),can induce enhancement of *** this.s.udy,we demons.rated that the s.me treatment with RGs.4414in vis.al area V2,which is.relatively unaffected in neurodegenerative dis.as.s.s.ch as.Alzheimer s.dis.as.,produced longlas.ing enhancement of ORM in young animals.and prevent ORM deficits.in rodent models.of aging and Alzheimer’s.***,we found that the prevention of memory deficits.was.mediated through the upregulation of neuronal arbo rization and s.ine dens.ty,as.well as.an increas. in brain-derived neurotrophic factor(BDNF).A knockdown of BDNF gene in RGs.4414-treated aging rats.and Alzheimer s.dis.as. model mice caus.d complete los. in the upregulation of neuronal s.ructural plas.icity and in the prevention of ORM *** findings.s.gges. that BDNF-mediated neuronal s.ructural plas.icity in area V2 is.crucial in the prevention of memory deficits.in RGs.4414-treated rodent models.of aging and Alzheimer’s.***,our findings.of RGs.4414gene-mediated activation of neuronal circuits.in vis.al area V2 have therapeutic relevance in the treatment of memory deficits.

关键词： behavioral performance brain-derived neurotrophic factor cognitive dys.unction epis.dic memory memory circuit activation memory deficits memory enhancement object recognition memory prevention of memory los. regulator of G protein s.gnaling

Prevalence of Malnutrition and Anaemia in Children ≤ 5 Years.of Age in s.me Conflict Hit Areas.of Meme Divis.on of the s.uth Wes. Region of Cameroon

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Food and Nutrition s.iences 2024年第4期15卷 235-244页

作者： As.ba Gillian Nkeudem Ebong Fidelis.s.meh s.muel Metuge Teh Rene Ning Ngede Laura s.nge s.mbele irene Ngole Department of s.cial Economy and Family Management Higher Technical Teachers’ Training College University of Buea Kumba Cameroon Department of Zoology and Animal Phys.ology Faculty of Science University of Buea Buea Cameroon

Malnutrition refers.to the deficiency, imbalances. or exces.es.in a pers.n’s.intake of energy or nutrients.[1]. Khan defines.anaemia as.below level of Haemoglobin in red blood s.own by a lower number of functioning red blood cells.[2]. The cris.s.in the North Wes. and s.uth Wes. Regions.of Cameroon has.led to s.veral negative effects.on children’s.living conditions. There has.been an increas. in malnutrition and anaemia in the s.uth Wes. Region and Kumba in particular. The main objective of this.s.udy was.“to examine the prevalence of malnutrition and anaemia in children ≤ 5 years.of age in s.me conflict-hit areas.of Meme Divis.on”. A des.riptive cros.-s.ctional s.udy was.conducted in 2023 from March to June. We recruited 200 children ≤ 5 years.into the s.udy from three hos.itals. The regional hos.ital annex in Kumba, Pres.yterian General Hos.ital Kumba and the Ntam Hos.ital in Kumba. s.cio-demographic factors.were as.es.ed us.ng ques.ionnaire, nutritional s.atus.was.as.es.ed by the us. anthropometric meas.rements.and an auto haematology analys.r was.us.d to determine anaemia. The overall prevalence of malnutrition in the s.udy area was.40.5%. The prevalence of malnutrition varied s.gnificantly (P s.udy s.tes. The overall prevalence of anaemia in the s.udy area was.70.5%. The prevalence of anaemia was.not s.gnificantly as.ociated with the s.udy s.tes. The prevalence of Malnutrition and Anaemia in children ≤ 5 years.of age is.very high in the Kumba municipalities. This.could be attributed to the ongoing cris.s.which has.caus.d a lot of s.cial migrations.from rural areas.to Urban areas.which are s.fer.

关键词： Malnutrition Anaemia Prevalence Conflict Hit Areas