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Brain age estimation:premise,promise,and problems

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Neural Regeneration Research 2025年第8期20卷 2313-2314页

作者： Jarrad Perron ji hyun Ko Graduate Program in Biomedical Engineering Price Faculty of EngineeringUniversity of ManitobaWinnipegMBCanada PrairieNeuro Research Centre Kleysen Institute for Advanced MedicineHealth Sciences CentreWinnipegMBCanada Department of Human Anatomy and Cell Science Rady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada

Premise:The com bined effects of modern healthcare practices which prolong lifespan and declining birthrates have created unprecedented changes in age demographics worldwide that are especially pronounced in Japan,South Korea,Europe,and North *** old age is the most significant predictor of dementia,global healthcare systems must rise to the challenge of providing care for those with neurodegenerative disorders.

关键词： estimation providing birth

Structural Analysis of FRIGIDA Flowering-Time Regulator

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Molecular Plant 2016年第4期9卷 618-620页

作者： Kyung-gi hyun Jee Eun Oh jihye Park Yoo-Sun noh ji-Joon Song Department of Biological Sciences KAIST Institute of the BioCentury KAIST Daejeon 34141 Korea School of Biological Sciences Seoul National University Seoul 151-747 Korea

Dear Editor,Flowering is a major developmental switch in the life cycle of flowering plants. FRIGIDA （FRI） activates FLOWERING LOCUS C （FLC） transcription, a major repressor of this switch regulating flow- ering time （Johanson et al., 2000）. FRI is highly conserved and many natural variations in FRI are found to affect flowering time. However, little is known about the molecular characteristics of FRI.

关键词： Flowering major developmental

Room-temperature synthesis of ZrSnO4 nanoparticles for electron transport layer in efficient planar hetrojunction perovskite solar cells

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Journal of Materials Science & Technology 2020年第7期42卷 38-45页

作者： Young Wook noh In Su jin Sang hyun Park Jae Woong Jung Department of Advanced Materials Engineering for Information&Electronics Kyung Hee University1732 Deogyeong-daeroGiheung-guYongin-siGyeonggi-do 446-701Republic of Korea

The interface engineering plays a key role in controlled optoelectronic properties of perovskite photovoltaic devices,and thus the electron transport layer(ETL)material with tailored optoelectronic properties remains a challenge for achieving high photovoltaic performance of planar perovskite solar cells(PSCs).Here,the fine and crystalline zirconium stanate(ZrSnO4)nanoparticles(NPs)was synthesized at low temperature,and its optoelectronic properties are systematically *** from the favorable electronic structure of ZrSnO4 NPs for applications in ETL,efficient electron transport and extraction with suppre s sed charge recombination are achieved at the interface of perovskite *** a result,the optimized ZrSnO4 NPs synthesized at room-temperature deliver the optimized power conversion efficiency up to 16.76%with acceptable *** work opens up a new class of ternary metal oxide for the use in ETL of the planar PSCs and should pave the way toward designing new interfacial materials for practical optoelectronic devices.

关键词： ZrSnO4 Electron transport layer Nanoparticles Perovskite solar cells

Electrochemical characteristics of phosphorus doped Si-C composite for anode active material of lithium secondary batteries

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中国有色金属学会会刊：英文版 2009年第4期19卷 1018-1022页

作者： Jae-hyun noh Kwan-Yo ung LEE Joong-Kee LEE Battery Research Center Korea Institute of Science and Technology Department of Chemical and Biological Engineering Korea University

Phosphorus doped silicon-carbon composite particles were synthesized through a DC arc plasma ***(SiH4) and methane(CH4) were introduced into the reaction chamber as the precursor of silicon and carbon,***(PH3) was used as a phosphorus dopant *** of synthesized particles were carried out by scanning electron microscopy(SEM),X-ray diffractometry(XRD),X-ray photoelectron spectroscopy(XPS) and bulk resistivity *** properties were investigated by cyclic test and electrochemical voltage spectroscopy(EVS).In the experimental range,phosphorus doped silicon-carbon composite electrode exhibits enhanced cycle performance than intrinsic silicon and phosphorus doped *** can be explained that incorporation of carbon into silicon acts as a buffer matrix and phosphorus doping plays an important role to enhance the conductivity of the electrode,which leads to the improvement of the cycle performance of the cell.

关键词：电化学特性磷掺杂负极活性材料磷硅电池材料锂离子 X射线光电子能谱扫描电子显微镜

Anti-obesity Effects of Ginsenosides in High-Fat Diet-Fed Rats

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Chinese Journal of Integrative Medicine 2019年第12期25卷 895-901页

作者： hyun-Jung Park ji hyun Kim Insop Shim Department of Physiology College of MedicineKyung Hee UniversitySeoul(130-701)Republic of Korea Department of Food Science&Biotechnology College of Science and EngineeringSuwon-si(16227)Republic of Korea

Objective: To examine the anti-obesity effects of ginsenosides in Korea Red Ginseng(KRG, Panax ginseng) in rats fed with a high-fat diet(HFD). Methods: Twenty-five 4-week-old obesity rats after receiving an HFD for 5 weeks;subsequently, they were additionally treated with ginsenosides Rb1, Rd, Rg1, or Re(10 mg/kg, intraperitoneal injection) for a further 3 weeks(n=5 in each group). The control rats were fed a normal diet. The food consumption, body weight, locomotor activity, serum lipids, adipose tissues, nitric oxide(NO) expression, leptin, neuropeptide Y(NPY), cholecystokinin(CCK) in the brains were measured. Results: In the HFD-fed rats, body weight, body fat mass, serum levels of leptin and NO were significantly higher than in the control rats(P<0.05 or P<0.01). However, the treatment of Rd, Re, and Rb1 markedly decreased body fat mass and body weight(P<0.05). The serum level of leptin and NO in ginsenoside-treated rats were markedly lower than the control group(P<0.01). The expression of NPY and CCK in the hypothalamic nuclei showed insignificant difference among groups. However, the expression of NPY immunoreactive neurons in the hypothalamus was significantly reduced in the Rb1-treated group(P<0.05). Conclusion: PD-type ginsenoside Rb1 from the crude saponins of KRG may be a useful compound for the treatment of obesity and related disorders through the modulation of peripheral and central appetite-regulating signals.

关键词： Panax ginseng ginsenosides hypothalamus obesity

Effect of Length Scale Tuning of Background Error in WRF-3DVAR System on Assimilation of High-Resolution Surface Data for Heavy Rainfall Simulation

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Advances in Atmospheric Sciences 2012年第6期29卷 1142-1158页

作者： ji-hyun HA Dong-Kyou LEE Atmospheric Sciences Program School of Earth and Environmental SciencesSeoul National UniversitySeoul 151-747Korea

We investigated the impact of tuning the length scale of the background error covariance in the Weather Research and Forecasting （WRF） three-dimensional variational assimilation （3DVAR） system. In particular, we studied the effect of this parameter on the assimilation of high-resolution surface data for heavy rainfall forecasts associated with mesoscale convective systems over the Korean Peninsula. In the assimilation of high-resolution surface data, the National Meteorological Center method tended to exaggerate the length scale that determined the shape and extent to which observed information spreads out. In this study, we used the difference between observation and background data to tune the length scale in the assimilation of high-resolution surface data. The resulting assimilation clearly showed that the analysis with the tuned length scale was able to reproduce the small-scale features of the ideal field effectively. We also investigated the effect of a double-iteration method with two different length scales, representing large and small-length scales in the WRF-3DVAR. This method reflected the large and small-scale features of observed information in the model fields. The quantitative accuracy of the precipitation forecast using this double iteration with two different length scales for heavy rainfall was high; results were in good agreement with observations in terms of the maximum rainfall amount and equitable threat scores. The improved forecast in the experiment resulted from the development of well-identified mesoscale convective systems by intensified low-level winds and their consequent convergence near the rainfall area.

关键词： WRF 3DVAR tuning surface data heavy rainfall

Functional Insights of Plant GSK3-like Kinases： Multi-Taskers in Diverse Cellular Signal Transduction Pathways

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Molecular Plant 2015年第4期8卷 552-565页

作者： ji-hyun Youn Tae-Wuk Kim Department of Life Science College of Natural Sciences Hanyang University Seou1133-791 Korea Naturat Science Institute Hanyang University Seou1133-791 Korea

The physiological importance of GSK3-like kinases in plants emerged when the functional role of plant GSK3-like kinases represented by BIN2 was first elucidated in the brassinosteroid （BR）-regulated signal transduction pathway. While early studies focused more on understanding how GSK3-like kinases regulate BR signaling, recent studies have implicated many novel substrates of GSK3-like kinases that are involved in a variety of cellular processes as well as BR signaling. Plant GSK3-like kinases play diverse roles in physiological and developmental processes such as cell growth, root and stomatal cell development, flower development, xylem differentiation, light response, and stress responses. Here, we review the progress made in recent years in understanding the versatile functions of plant GSK3-like kinases. Based on the relationship between GSK3-like kinases and their newly identified substrates, we discuss the physiological and biochemical relevance of various cellular signaling mediated by GSK3-like kinases in plants.

关键词： GSK3-like kinases brassinosteroids signal transduction pathway Arabidopsis rice

Origami multi-layer space shield for cylindrical space structure

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Chinese Journal of Aeronautics 2024年第10期37卷 294-312页

作者： ji-Hun CHA ji-Sub noh Sarath Kumar SATHISH KUMAR Dohyeon jiN Dae-Young LEE Chun-Gon KIM Department of Aerospace Engineering Chosun UniversityGwangju 61452Republic of Korea Department of Aerospace and Software Engineering Gyeongsang National UniversityGyeongsangnam-do 52828Republic of Korea Department of Aerospace Engineering Seoul National UniversitySeoul 08826Republic of Korea Department of Aerospace Engineering KAISTDaejeon 34141Republic of Korea

The multidisciplinary space environment,encompassing orbital debris,cosmic radiation,and solar radiative heat,poses significant risks to spacecraft and astronauts,necessitating efficient and effective shielding solutions.A multi-layer shield with wide spacing has been proven to be an effective way to shield the spacecraft from space debris impact;however,due to the limited volume of the payload fairing,it was not feasible to apply a multi-layer shield to the spacecraft *** the origami design,the shield maintains a compact form during launch and subsequently expands in outer space to enhance *** geometric analysis,it has been confirmed that the deployable multi-layer space shield can occupy less space than conventional space shield structures while expanding into wider shield intervals and multiple *** hypervelocity impact experiments,it was confirmed that as the bumper spacing of the multi-layer space shield expands,its ballistic performance becomes superior to conventional space *** deployable multi-layer space shield can reduce not only hypervelocity impacts but also solar radiative heat using the same mechanism as multi-layer *** cosmic radiation dose analysis,it has been confirmed that the multi-layer space shield is effective in cosmic radiation shielding compared to conventional space structures.

关键词： Hybrid composite Origami Hypervelocity impact Space environment Space debris Cosmic radiation

Improved continuous precipitation kinetics and tensile properties of extruded AZ80 alloy through {10-12} twin formation

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Journal of Magnesium and Alloys 2023年第9期11卷 3323-3337页

作者： hyun ji Kim Sumi Jo Sung Hyuk Park Department of Materials Science and Metallurgical Engineering Kyungpook National UniversityDaegu 41566the Republic of Korea

This study investigates the effect of{10-12}deformation twins on the continuous precipitation behavior of an extruded Mg-8.0Al-0.5Zn-0.2Mn(AZ80)alloy during *** extruded AZ80 alloy is compressed along the transverse direction to introduce{10-12}twins,followed by an aging treatment at 300℃.The extruded material exhibits a twin-free microstructure with low internal strain energy,whereas the pre-twinned material possesses abundant{10-12}twins and has high internal strain *** aging results reveal that the peak-aging time of the pre-twinned material(1 h)is one-eighth of that of the extruded material(8 h).Although Mg_(17)Al_(12)continuous precipitates(CPs)are observed in both the peak-aged materials,these CPs are much smaller and more densely distributed in the pre-twinned material despite the significantly shorter aging *** CPs size in the peak-aged materials increases in the following order:twinned region in the pre-twinned material(0.47μm)

关键词： AZ80 alloy {10-12}twin Aging Continuous precipitation Tensile properties