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第三届中日韩气象学术会议

作者： Dong-In Lee Ji-Young Gu Min jang Kil-Jong Seo Dong-soon Kim Mi-Young Kang Sang-Min jang Geun-Ok Lee Department of Environmental Atmospheric Sciences Pukyong National University（599-Daeyeon-3-dongNamguBusan 608-737Korea） Department of Environmental Atmospheric Sciences Pukyong National University（599-Daeyeon-3-dongNamguBusan 608-737Korea） Department of Environmental Atmospheric Sciences Pukyong National University（599-Daeyeon-3-dongNamguBusan 608-737Korea） Department of Environmental Atmospheric Sciences Pukyong National University（599-Daeyeon-3-dongNamguBusan 608-737Korea） Department of Environmental Atmospheric Sciences Pukyong National University（599-Daeyeon-3-dongNamguBusan 608-737Korea） Department of Environmental Atmospheric Sciences Pukyong National University（599-Daeyeon-3-dongNamguBusan 608-737Korea） Department of Environmental Atmospheric Sciences Pukyong National University（599-Daeyeon-3-dongNamguBusan 608-737Korea） Department of Environmental Atmospheric Sciences Pukyong National University（599-Daeyeon-3-dongNamguBusan 608-737Korea）

＜正＞In summer season,Korea,Japan,Taiwan and the mainland are influenced several severe weather events such as Changrna/Meiyu/Baiu front,typhoon,strong low pressure,and local heavy *** events are usually accompanied heavy precipitation and *** convective systems developing in a moist environment such as over the East China Sea are one of the major targets to reveal in meteorology as they develop rapidly and produce heavy rainfall on these *** clarify the development of the mechanism of heavy precipitation system and study its occurrence mechanism,we had field experiments in Jejudo and *** analyzed the synoptic condition by using NCEP/NCAR reanalysis data and kinematical characteristics of precipitation system by dual Doppler radar *** several cases observed,especially the case that Changma front influenced indirectly by typhoon "EWINIAR" located in south coast around Jejudo recorded heavy rainfall amount and showed special features and *** field characteristic, vertical thermal condition and synoptic condition played important *** understand occurrence mechanism of these heavy precipitation systems and monsoon etc.,long-term intensive observations should be done continuously around the East China Sea.

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Attenuated FOLFIRINOX in the salvage treatment of gemcitabine-refractory advanced pancreatic cancer: a phase II study

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Cancer Communications 2018年第1期38卷 344-351页

作者： Jung Hoon Kim Sang-Cheol Lee Sung Yong Oh Seo-Young Song Namsu Lee Eun Mi Nam soonil Lee In Gyu Hwang Hyo Rak Lee Kyu Taek Lee Sang-Byung Bae Han Jo Kim Joung soon jang Do Hyoung Lim Hyun Woo Lee Seok Yun Kang Jung Hun Kang Department of Internal Medicine Institute of Health SciencesGyeongsang National University15 Jinju-daero 816beon-gilJinju 52727Republic of Korea Divsion of Hematology and Oncology Department of Internal MedicineSoonchunhyang University Hospital CheonanCheonan 31151Republic of Korea Department of Internal Medicine Dong-A University HospitalBusan 49201Republic of Korea Department of Internal Medicine Kangwon National University School of MedicineChuncheon 24289Republic of Korea Divsion of Hematology and Oncology Department of Internal MedicineSoonchunhyang University Hospital SeoulSeoul 04401Republic of Korea Department of Internal Medicine Ewha Womans UniversityCollege of MedicineSeoul 07985Republic of Korea Department of Internal Medicine Dankook University HospitalCheonan 31116Republic of Korea Department of Internal Medicine Chung-Ang UniversityCollege of MedicineSeoul 06973Republic of Korea Division of Hematology and Medical Oncology Department of Internal MedicineKorea Cancer HospitalSeoul 01812Republic of Korea Department of Hematology-Oncology Ajou University HospitalSuwon 16499Republic of Korea

Background:Combination therapy with oxaliplatin,irinotecan,fluorouracil,and leucovorin(FOLFIRINOX)chemotherapy drastically improves survival of advanced pancreatic cancer ***,the efficacy of FOLFIRINOX as a second-line treatment after gemcitabine failure has not been tested *** investigated the feasibility and safety of attenuated FOLFIRINOX in patients with gemcitabine-refractory advanced pancreatic ***:A multicenter phase II prospective open-label,single-arm study was conducted at 14 *** with histologically proven invasive ductal pancreatic adenocarcinoma,a measurable or evaluable lesion,Eastern Cooperative Oncology Group performance status 0 or 1,adequate organ function,and aged 19 years or older were *** FOLFIRINOX consisted of oxaliplatin 65 mg/m2,irinotecan 135 mg/m2,and leucovorin 400 mg/m2 injected intravenously on day 1 and 5-fluorouracil 2000 mg/m2 continuously infused intravenously over 46 h on days 1-2,repeated every 2 *** primary endpoint was progression-free survival from the initiation of *** endpoints were the objective response rate,disease control rate,overall survival,safety,and *** estimated overall survival and progression-free survival using the Kaplan-Meier ***:We enrolled 39 patients from 14 *** objective response rate was 10.3%,while the disease control rate was 64.1%.The 6-month and 1-year overall survival rates were 59.0%and 15.4%,*** progression-free survival and overall survival were 3.8 months(95%confidence interval[CI]1.5-6.0 months)and 8.5 months(95%CI 5.6-11.4 months),*** 3 or 4 adverse events were neutropenia(41.0%),nausea(10.3%),anorexia(10.3%),anemia(7.7%),mucositis(7.7%),pneumonia/pleural effusion(5.1%),and fatigue(5.1%).One treatment-related death attributable to septic shock ***:Attenuated FOLFIRINOX may be promising as a second-line therapy for gemcitabin

关键词： Attenuated FOLFIRINOX Second-line Pancreatic cancer Gemcitabine

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Outcome after endoscopic submucosal dissection for early gastric cancer in Korea

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World Journal of Gastroenterology 2011年第31期17卷 3591-3595页

作者： Jun Haeng Lee Su Jin Hong Jae Young jang Seong Eun Kim Sang Young Seol Department of Medicine Samsung Medical CenterSungkyunkwan University School of Medicine Department of Internal Medicine Digestive Disease CenterInstitute for Digestive ResearchSoon Chun Hyang University College of Medicine Department of Internal Medicine Kyung Hee University College of Medicine Department of Internal Medicine Ewha Womans University School of MedicineEwha Medical Research Institute Division of Gastroenterology and Hepatology Department of Internal MedicineInje University College of Medicine

Endoscopic treatment,such as endoscopic mucosal resection(EMR) and endoscopic submucosal dissection(ESD),has been established as one of the treatment options for selected cases with early gastric cancer(EGC).Most studies on this topic have been carried out by researchers in ***,the experience in EMR/ESD for EGC outside Japan is increasingly *** Korea,gastric cancer is the most common malignant disease,and the second leading cause of cancer ***,EMR for EGC is widely performed in many centers in *** results with a shortterm follow-up period are very promising in *** resection rate of EMR was 37.8%-94.3%,and that of ESD was 77.4%-93.1%.In this review,we will provide an overview of the outcomes of endoscopic treatments in Korea.

关键词： Early gastric cancer Endoscopic mucosal resection Endoscopic submucosal dissection Outcome

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Nuclear Localization of Glyceraldehyde 3-Phosphate Dehydrogenase in Senescent Human Diploid Fibroblasts

Nuclear Localization of Glyceraldehyde 3-Phosphate Dehydroge...

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The 8th Asia/Oceania Regional Congress of Gerontology and Geriatrics

作者： Eui-Ju Yeo Hyun Jin Kwon Ji Hyun.Rhim Ik soon.jang Sang Chul.Park Department of Biochemistry Gachon University of Medicine and Science Department of Biochemistry Gachon University of Medicine and Science Department of Biochemistry and Molecular Biology Aging and Apoptosis Research Center Seoul National University College of MedicineSeoul Korea Basic Science Institute Gwangju Center Department of Biochemistry and Molecular Biology Aging and Apoptosis Research Center Seoul National University College of MedicineSeoul

＜正＞In our studies of genes differentially expressed by lysophosphatidic acid（LPA）and the expressional changes caused by aging,we found that the level of glyceraldehyde 3-phosphate dehydrogenase（GAPDH:E.C. 1.2.1...

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CHARACTERISATION AND CYTOKINE RESPONSE TO WEST NILE SUB-VIRAL PROTEINS EXPRESSED IN CELLS

CHARACTERISATION AND CYTOKINE RESPONSE TO WEST NILE SUB-VIRA...

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The 4th Asian-Pacific Organization for Cell Biology Congress Cell Biology in the Post-Genomic Era

作者： Raghavan Bhuvana Kantham soon Yuan Chye John Jia En Chua Justin jang Hann Chu Mary Mah-Lee Ng Department of Microbiology National University of Singapore5Science drive 2Singapore 117597

During wild type West Nile virus infections in Vero cells, co-migration of both the Envelope (E) and the Capsid (C) proteins from the perinuclear region to the plasma membrane were visualized using immuno-fluorescent ...

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Identification and Determination of Phenolic Compounds in Rapeseed Meals (Brassica napus L.)

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Journal of Agricultural Chemistry and Environment 2015年第1期4卷 14-23页

作者： Si-Chang Yang Mariadhas Valan Arasu Jin-Hyuk Chun Young-Seok jang Yong-Hwa Lee In Ho Kim Ki-Taek Lee soon-Taek Hong Sun-Ju Kim Bio-Environmental and Chemistry Chungnam National University Daejeon Republic of Korea Department of Botany and Microbiology Addiriyah Chair for Environmental Studies College of Science King Saud University Riyadh Saudi Arabia Bio-Energy Crop Center National Institute of Food Science Rural Development Administration Muan-County Republic of Korea Department of Animal Resource & Science Dankook University Cheonan-Si Republic of Korea Food Science and Technology Chungnam National University Daejeon Republic of Korea

This study aimed in the identification and quantification of phenolic compounds in different four varieties of rapeseeds (Brassica napus L.) using LC-MS and HPLC. LC-MS analysis guided to identify 12 phenolic compounds including sinapine, sinapine(4-O-8')guaiacyl, feruloyl choline(4-O-8') guaiacyl, kaempferol-3-O-sinapoyl-sophoroside-7-O-glucoside, kaempferol-3-O-β-sophoroside, cyclic spermidine-alkaloid, feruloyl choline(5-8')guaiacyl, kaempferol-sinapoyl-trihexoside,1,2-di- O-sinapoyl-gentiobiose, 1,2-di-O-sinapoyl-glucose, feruloyl choline(4-O-8')guaiacyl-di-sinapoyl, and sinapine(4-O-8')guaiacyl-di-sinapoyl, respectively. Total phenolic compounds in rapeseed meals were ranged from 38.50 (2012 “Sunmang”) to 63.95 mg/g dry weight (DW) (2014 Jeju local cultivar). Main phenolic compositions were cyclic spermidine-alkaloid, kaempferol, feruloyl choline, and sinapine. Sinapine was predominant compound among all the samples ranged from 29.74 to 52.24 mg/g DW (mean 79% of total phenolic contents). This study provided the information for the variation of phenolic compounds between the varieties of rapeseeds and the cultivation periods. Furthermore, this information can be developed for bio-energy industry as a reducer of the cost of the bio-energy products.

关键词： LC-MS Analysis HPLC Analysis Rapeseed Meal Phenolic Compounds

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保障医疗设备硬件系统功能安全的有效方法(英文)

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中国医疗设备 2015年第12期30卷 27-33,15页

作者： KIM Gi-young WANG Da-wei PARK Ho-joon jang Joong-soon Department of Industrial Engineering Ajou University Medical Device Evaluation Engineering Center Korea Testing Laboratory

A medical device is an instrument that includes components,parts,or accessories to diagnose or treat *** the complexity of medical devices has increased in recent years,functional safety and basic safety are required to ensure the overall device *** safety is part of the overall safety that relates to the equipment under control(EUC)and to the EUC control system that depends on the correct functionality of the electrical/electronic/programmable electronic(E/E/PE)safety-related *** study proposes approach methods to functional safety of medical devices for which it is important to correctly identify the safety functions and the safety integrity level(SIL).The relationship between the functional safety and essential performance is identified focusing on the safety *** essential performance of E/E/PE systems is defined as the safety function of the functional *** target SIL of the essential performance is determined according to the potential risk levels,based on the classification rules of medical *** approach is applied to the pulse oximeter as a case *** target SIL for the functionality of the power-failure alarm condition is determined to be *** target SILs of other functions are determined as SIL2.

关键词： functional safety medical device essential performance classification rule safety function pulse oximeter

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Heavy metal chemistry in soils received long-term application of organic wastes

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Journal of Agricultural Chemistry and Environment 2012年第1期1卷 1-9页

作者： soon-Ik Kwon Yeon-Ah jang Kye-Hoon Kim Goo-Bok Jung Min-Kyeong Kim Hae Hwang Mi-Jin Chae Seung-Chang Hong Kyu-Ho So Sun-Gang Yun Kwon-Rae Kim Gyeongnam National University of Science and Technology Jinju South Korea National Academy of Agricultural Science (NAAS) RDA Suwon South Korea The University of Seoul Seoul South Korea

This study was carried out to understand the long-term effect of organic waste treatment on the fate of heavy metals originated from the organic wastes, together with examination of changes in soil properties. For this, the soils received three different organic wastes (municipal sewage sludge, alcohol fermentation processing sludge, pig manure compost) in three different rates (12.5, 25, 50 ton/ha/yr) for 7 years (1994 - 2000) were used. To see the long-term effect, plant growth study and soil examination were conducted twice in 2000 and 2010, respectively. There was no additional treatment of organic wastes for post ten years after ceasing organic waste treatment for seven years. Soil examination conducted in 2010 showed decreases in soil pH, EC, total nitrogen, organic matter, available phosphorus, exchangeable cations and heavy metal contents in all soils received organic wastes compared to the results obtained in 2000. Speciation of heavy metals in soil through sequential extraction showed that organically bound Cu was the dominant species in all treatment and exchangeable Cu was increased in the plots treated with municipal sewage sludge and alcohol fermentation processing sludge. organically bound Ni increased from 25% - 30% to 32% - 45% in 2010 inall treatment while Pb showed increase in carbonate form in all treatments. Zn existed mainly as sulfide and residual forms, showing increases in organically bound form in all treatment during post ten years.

关键词： Heavy Metal Long-Term Application Organic Wastes Sequential Extraction

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Risk factors of biliary intervention by imaging after livingdonor liver transplantation

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World Journal of Gastroenterology 2016年第7期22卷 2342-2348页

作者： soon Kyu Lee Jong Young Choi Dong Myung Yeo Young Joon Lee Seung Kew Yoon Si Hyun Bae Jeong Won jang Hee Yeon Kim Dong Goo Kim Young Kyoung You Division of Hepatology Department of Internal MedicineCollege of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Radiology College of MedicineThe Catholic University of KoreaSeoul 06591South Korea Department of Surgery College of MedicineThe Catholic University of KoreaSeoul 06591South Korea

AIM:To determine the risk factors of biliary intervention using magnetic resonance cholangiopancreatography(MRCP) after living donor liver transplantation(LDLT).METHODS: We retrospectively enrolled 196 patients who underwent right lobe LDLT between 2006 and 2010 at a single liver transplantation center. Direct duct-to-duct biliary anastomosis was performed in all 196 patients. MRCP images routinely taken 1 mo after LDLT were analyzed to identify risk factors for biliary intervention during follow-up, such as retrograde cholangiopancreatography or percutaneous transhepatic biliary drainage. Two experienced radiologists evaluated the MRCP findings, including the anastomosis site angle on three-dimensional images, the length of the filling defect on maximum intensity projection, bile duct dilatation, biliary stricture, and ***: Eighty-nine patients underwent biliary intervention during follow-up. The anastomosis site angle [hazard ratio(HR) = 0.48; 95% confidence interval(CI), 0.30-0.75, P < 0.001], a filling defect in the anastomosis site(HR = 2.18, 95%CI: 1.41-3.38,P = 0.001), and biliary leakage(HR = 2.52, 95%CI: 1.02-6.20, P = 0.048) on MRCP were identified in the multivariate analysis as significant risk factors for biliary intervention during follow-up. Moreover, a narrower anastomosis site angle(i.e., below the median angle of 113.3°) was associated with earlier biliary intervention(38.5 ± 4.2 mo vs 62. 1 ± 4.1 mo, P < 0.001). Kaplan-Meier analysis comparing biliary intervention-free survival according to the anastomosis site angle revealed that lower survival was associated with a narrower anastomosis site angle(36.3% vs 62.0%, P < 0.001).CONCLUSION: The biliary anastomosis site angle in MRCP after LDLT may be associated with the need for biliary intervention.

关键词： Magnetic resonance cholangiopancreatography Liver transplantation Living donor Biliary intervention Endoscopic retrograde cholangiopancreatography Percutaneous transhepatic biliarydrainage

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Analysis of Cancer Incidence among Korean Nuclear Power Plant Workers

Analysis of Cancer Incidence among Korean Nuclear Power Plan...

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The Second Asian and Oceanic Congress for Radiation Protection

作者： Meeseon JEONG Young-Woo JIN Young Khi LIM Soo Keun KIM Byoung-Il LEE Youn Koun jang Sook Hee SUNG Ill Keun PARK Yeon Joo LEE Chong-soon KIM Radiation Health Research Institute KHNPSeoulKorea Radiation Health Research Institute KHNPSeoulKorea Radiation Health Research Institute KHNPSeoulKorea Radiation Health Research Institute KHNPSeoulKorea Radiation Health Research Institute KHNPSeoulKorea Radiation Health Research Institute KHNPSeoulKorea Radiation Health Research Institute KHNPSeoulKorea Radiation Health Research Institute KHNPSeoulKorea Radiation Health Research Institute KHNPSeoulKorea Radiation Health Research Institute KHNPSeoulKorea

Epidemiological studies of nuclear industry workers have important role to examine the health effect of low dose and low dose-rate radiation *** this study we analyzed the cohort of Korean nuclear power plants *** cohort consists of 7,459 male workers exposed to ionizing radiation and 6,508 controls without exposure *** paper presents the results of analysis on their cancer incidence between 1993 and 2002.A total of 58 cancers were ascertained for radiation workers and 50 for non-radiation ***-standardized rate ratio for two groups was 1.09（95% CI:0.74,1.62）.Trend test showed that cancer incidence rate in individual dose group was not significantly increased with increasing cumulative dose（p=0.2506）.Excess relative risk for all cancers combined was 6.77（95% CI:-4.02,27.54）per sievert,suggesting no statistically significant association between radiation dose and cancer *** of this study are not conclusive because of considerable *** size of the cohort,small cases of cancer incidence,and young ages of subjects limit the power of the *** we need further follow-up and the expansion of cohort to increase the power and to obtain stable risk estimate.

关键词： radiation workers cohort standardized incidence ratio rate ratio excess relative risk

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