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多次使用钆布醇后苍白球T1信号减低:多期动态多回波序列评估

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国际医学放射学杂志 2018年第3期 356-357页

作者： k.M.kang S.H.Choi M.hwang T.j.Yun j.H.kim C.H.Sohn 刘臻 Department of Radiology Seoul National University Hospital

摘要目的通过多期动态多回波(MDME)MR成像序列来验证肾功能正常的颅脑增强病人中大环类对比剂钆布醇与T1值的关系。材料与方法本回顾性研究经机构伦理委员

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In situ total strain measurements revealing the strain mechanism of Pb(Mg_(1/3)Nb_(2/3))O_(3)ePbTiO_(3) single crystals

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journal of Materiomics 2021年第4期7卷 693-698页

作者： hwang-Pill kim Geon-ju Lee jae-Hyeon Cho Woo-Seok kang Sang-Goo Lee Ho-Yong Lee Wook jo School of Materials Science and Engineering&jülich-UNIST joint Leading Institute for Advanced Energy Research Ulsan National Institute of Science and Technology(UNIST)Ulsan44919Republic of Korea IBULe Photonics Inc.7-39Songdo-dongYeonsu-guIncheon21999Republic of Korea Department of Materials Science and Engineering Sun Moon UniversityAsan31460Republic of Korea

The strain behavior of 0.71 Pb(Mg_(1/3)Nb_(2/3))O_(3)ePbTiO_(3)(PMN-PT)single crystal prepared by a solidstate single crystal growth method was investigated on two most widely used orientations,i.e.,(001)-and(011)-oriented.A special emphasis was put on the correlation among longitudinal and transverse strains and the consequent volume *** show that seemingly different strain behavior of(001)-and(011)-oriented crystals has the same origin,and the underlying mechanism excludes possible contribution from the frequently cited polarization *** situ monitoring of electric field induced Poisson’s ratio further suggested that the polarization vectors contributing to the strain properties in PMN-PT are not confined to a unique direction forced by the crystallographic symmetry but possess a span of angular range.

关键词： Piezoelectricity Single crystal PMN-PT Radial strain Poisson’s ratio

Novel C-17 spirost protostane-type triterpenoids from Alisma plantago-aquatica with antiinflammatory activity in Caco-2 cells

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Acta Pharmaceutica Sinica B 2019年第4期9卷 809-818页

作者： Qinghao jin jianqing Zhang jinjun Hou Min Lei Chen Liu Xia Wang Yong Huang Shuai Yao Bang Yeon hwang Wanying Wu Dean Guo Shanghai Institute of Materia Medica Chinese Academy of SciencesShanghai 201203China School of Pharmacy Shenyang Pharmaceutical UniversityShenyang 110016China University of Chinese Academy of Sciences Beijing 100049China College of Pharmacy Chungbuk National UniversityCheongju 2816South Korea

Twenty-one protostane-type triterpenoids with diverse structures, including nine new compounds(1 e9), were isolated from the of Alisma plantago-aquatica Linn. Structurally, alisolides A-F(1 e6), composed of an oxole group coupled to a five-membered ring, represent unusual C-17 spirost protostane-type triterpenoids. Alisolide H(8) is a novel triterpenoid with an unreported endoperoxide bridge. Alisolide I(9) represents the first example of 23,24-acetal triterpenoid. Their structures were elucidated based on spectroscopic analysis, wherein the absolute configurations of 4-6, 8 were further confirmed by the Mo2(OAc)4-induced ECD method. Furthermore, all isolates were evaluated for their inhibitory effects on LPS-induced NO production in Caco-2 cells, and all the compounds showed remarkable inhibitory activities, with IC50 values in the range of 0.76 e38.20 mmol/L.

关键词： Alisma plantago-aquatica Linn. Protostane-type triterpenoids Caco-2 cells LPS-induced NO production

综合成本变化对中国产业结构升级的影响——基于产业比较优势的中介效应

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江淮论坛 2020年第5期 65-74页

作者：杨青龙金磊 jeeseon hwang 南京财经大学国际经贸学院南京210023 首尔国立大学社会科学学院韩国首尔08826

产业结构升级的基本方向由综合成本及其子成本所塑造的产业比较优势所决定。通过测算中国31个省(自治区、直辖市)2000—2016年的生产成本、交易成本、环境成本、知识成本,并在此基础上加权合成“综合成本”,进而利用中国省际面板数据构... 详细信息

产业结构升级的基本方向由综合成本及其子成本所塑造的产业比较优势所决定。通过测算中国31个省(自治区、直辖市)2000—2016年的生产成本、交易成本、环境成本、知识成本,并在此基础上加权合成“综合成本”,进而利用中国省际面板数据构建计量经济模型实证研究综合成本及其子成本变化对产业结构升级的影响。与此同时,构建了产业比较优势指数,具体研究比较优势的中介效应。研究表明,综合成本及其子成本上涨不利于产业结构合理化;综合成本总量上涨阻碍了中国产业结构高级化,但其子成本上涨对产业结构高级化的影响不尽相同;对东部地区、中部地区和西部地区的分样本检验表明,综合成本对产业结构升级的影响在不同地区存在着明显的异质性特征。为更好地推动中国产业结构升级,应通过推动市场化改革,完善生产要素的定价机制;通过着力于制度创新,改善企业的营商环境;通过优化资源环境税费体系,强化企业的生态自觉;通过改进外部环境,推动知识要素扩散和传播。

关键词：综合成本产业结构升级产业比较优势中介效应

Multicenter evaluation of recurrence in endoscopic submucosal dissection and endoscopic mucosal resection in the colon:A Western perspective

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World journal of Gastrointestinal Endoscopy 2023年第6期15卷 458-468页

作者： Mike T Wei Margaret j Zhou Andrew A Li Andrew Ofosu joo Ha hwang Shai Friedland Department of Gastroenterology and Hepatology Stanford University Medical CenterPalo AltoCA 94306United States Department of Gastroenterology University of Cincinnati College of MedicineCincinnatiOH 45267United States

BACkGROUND While colon endoscopic mucosal resection(EMR)is an effective technique,removal of larger polyps often requires piecemeal resection,which can increase recurrence *** submucosal dissection(ESD)in the colon offers the ability for en bloc resection and is well-described in Asia,but there are limited studies comparing ESD vs EMR in the *** To evaluate different techniques in endoscopic resection of large polyps in the colon and to identify factors for *** The study is a retrospective comparison of ESD,EMR and knife-assisted endoscopic resection performed at Stanford University Medical Center and Veterans Affairs Palo Alto Health Care System between 2016 and ***-assisted endoscopic resection was defined as use of electrosurgical knife to facilitate snare resection,such as for circumferential ***≥18 years of age undergoing colonoscopy with removal of polyp(s)≥20 mm were *** primary outcome was recurrence on *** A total of 376 patients and 428 polyps were *** polyp size was greatest in the ESD group(35.8 mm),followed by knife-assisted endoscopic resection(33.3 mm)and EMR(30.5 mm)(Pknife-assisted endoscopic resection(31.1%)and EMR(20.2%)(Pknife-assisted endoscopic resection(0.0%)and ESD(1.3%)and highest in EMR(12.9%)(P=0.0017).En bloc polyp resection had significantly lower rate of recurrence(1.9%)compared to non-en bloc(12.0%,P=0.003).On multivariate analysis,ESD(in comparison to EMR)adjusted for polyp size was found to significantly reduce risk of recurrence[adjusted hazard ratio 0.06(95%CI:0.01-0.57,P=0.014)].CONCLUSION In our study,EMR had significantly higher recurrence compared to ESD and knife-assisted endoscopic *** found factors including resection by ESD,en bloc removal,and use of circumferentia

关键词： Endoscopic mucosal resection Endoscopic submucosal dissection Recurrence Colonoscopy Polypectomy

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kIMS地下实验中μ子本底的研究(英文)

高能物理与核物理 2005年第8期29卷 721-726页

作者：朱敬军康克军李元景李金 j.W.kwak H.Bhang S.Y.kim H.S.Lee j.Lee S.S.Myung M.j.Lee S.C.kim S.k.kim j.I.Lee Y.D.kim M.j.hwang Y.j.kwon I.S.Hahn H.j.kim 清华大学工程物理系北京100084 DMRC and School of Physics Seoul National University Seoul 151-742 Korea Department of Physics Sejong University Seoul 143-747 Korea Physics Department Yonsei University Seoul 120-749 Korea Department of Science Education Ewha Woman's University Seoul 120-750 Korea Physics Department Kyungpook National University Daegu 702-701 Korea

kIMS是寻找和研究暗物质WIMP的实验组.在WIMP寻找实验中,μ子是十分重要的一种本底.我们对地下700m深的Yangyang实验室内的μ子通量进行了测量.介绍了μ子探测器的结构和性能测试.描述了对μ子入射位置和角度分布的分析,并进行了蒙特卡... 详细信息

kIMS是寻找和研究暗物质WIMP的实验组.在WIMP寻找实验中,μ子是十分重要的一种本底.我们对地下700m深的Yangyang实验室内的μ子通量进行了测量.介绍了μ子探测器的结构和性能测试.描述了对μ子入射位置和角度分布的分析,并进行了蒙特卡罗模拟.实验室内的μ子通量测量值为(7.0±0.4)×10-8/s/cm2/sr.

关键词： kIMS 地下实验 μ子暗物质位置重建 WIMP

Modified TiO_(2)/In_(2)O_(3) heterojunction with efficient charge separation for visible-light-driven photocatalytic CO_(2) reduction to C_(2) product

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journal of Energy Chemistry 2024年第11期98卷 714-720页

作者： Mengfang Liang Xiaodong Shao ji Yoon Choi Young Dok kim Trang Thu Tran jeongyong kim Yosep hwang Min Gyu kim Yunhee Cho Sophia Akhtar Hyoyoung Lee Department of Chemistry Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea CO_(2) to Multicarbon Production Center Sungkyunkwan UniversitySuwon 16419Republic of Korea Institute for Quantum Biophysics(IQB) Sungkyunkwan UniversitySuwon 16419Republic of Korea Creative Research Institute Sungkyunkwan UniversitySuwon 16419Republic of Korea Beamline Research Division Pohang Accelerator Laboratory(PAL)Pohang University of Science and TechnologyPohang 37673Republic of Korea Department of Energy Science Sungkyunkwan UniversitySuwon 16419Republic of Korea

Utilizing sunlight to convert CO_(2) into chemical fuels could address the greenhouse effect and fossil fuel crisis,Heterojunction structure catalysts with oxygen vacancy are attractive in the field of photocatalytic CO_(2) ***,a modified TiO_(2)/In_(2)O_(3)(R-P2 5/In_(2)O_(3-x)) type Ⅱ heterojunction composite with oxygen vacancies is designed for photocatalytic CO_(2) reduction,which exhibits excellent CO_(2) reduction activity,with a C_(2) selectivity of 56.66%(in terms of R_(electron)).In situ Fourier-transform infrared spectroscopy(DRIFTS) and time-resolved photoluminescence(TR-PL) spectroscopy are used to reveal the intermediate formation of the photocatalytic mechanism and photogenerated electron lifetime,*** experimental characterizations reveal that the R-P25/In_(2)O_(3-x) composite shows a remarkable behavior for coupling C-C ***,efficient charge separation contributes to the improved CO_(2) conversion performance of *** work introduces a type Ⅱ heterojunction composite photocatalyst,which promotes understanding the CO_(2) reduction mechanisms on heterojunction composites and is valuable for the development of photocatalysts.

关键词： Heterojunction Oxygen vacancy Photocatalytic CO_(2)reduction C_(2)product Charge separation

Treatment and prognosis of hepatic epithelioid hemangioendothelioma based on SEER data analysis from 1973 to 2014

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Hepatobiliary & Pancreatic Diseases International 2020年第1期19卷 29-35页

作者： O kyu Noh Soon Sun kim Min jae Yang Sun Gyo Lim jae Chul hwang Hyo jung Cho jae Youn Cheong Sung Won Cho Department of Radiation Oncology Ajou University School of MedicineSuwonKorea Department of Biomedical Informatics Ajou University School of MedicineSuwonKorea Office of Biostatistics Ajou Research Institute for Innovative MedicineAjou University Medical CenterSuwonKorea Department of Gastroenterology Ajou University School of MedicineSuwonKorea

Background: Hepatic epithelioid hemangioendothelioma (HEH) is a rare tumor of vascular origin with an unknown etiology, a low incidence, and a variable natural course. We evaluated the management and prognosis of HEH from the Surveillance, Epidemiology and End Results (SEER) program and changes in treatment modalities of HEH over 30 years. Methods: From 1973 to 2014 in the SEER database, we selected patients diagnosed with HEH. We analyzed the clinical characteristics, patterns of management, and clinical outcomes of patients with HEH. Results: We identi ed 79 patients with HEH (median age: 54.0 years;male to female ratio: 1:2.6). The initial extent of disease was local in 22 (27.8%) patients, regional metastasis in 22 (27.8%), distant metas-tasis in 31 (39.2%) and unknown in 4 (5.1%). The median size of primary tumor was 3.85 cm (interquartile range, 2.50 7.93 cm). Among 74 patients with available management data, the most common manage-ment was no treatment (29/74, 39.2%), followed by chemotherapy only (22/74, 29.7%), liver resection-based (13/74, 17.6%), and transplantation-based therapy (6/74, 8.1%). The 5-year cancer-speci c survival rate was 57.8%. Patients who underwent surgical treatment had signi cantly higher survival than those who underwent non-surgical treatment (5-year survival;88% vs. 49%, P=0.019). Multivariate analysis revealed that surgical therapy was the only independent prognostic factor for survival (hazard ratio: 0.20, P=0.040). Conclusions: Resection or liver transplantation is worth considering for treatment of patients with HEH.

关键词： Hemangioendothelioma Epithelioid SEER program Liver transplantation Hepatectomy Liver neoplasms

Fuzzy-Based knowledge Discovery from Heterogeneous Data in Planting Systems for Elderly LOHAS

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journal of Electronic Science and Technology 2015年第1期13卷 45-53页

作者： Hung-Chih Hsueh jung-Yi jiang jen-Sheng Tsai Wen-Hao Tsai kuan-Rong Lee Yau-hwang kuo Department of Computer Science and Information Engineering National Cheng Kung University

In this paper, we propose a knowledge discovery method based on the fuzzy set theory to help elders with plant cultivation. Initially, the fuzzy sets are constructed by using the feature selection and statistical interval estimation. The min-max inference and the center of gravity defuzzification method are then used to output a candidate pattern set. Finally, a pattern discovery is adopted to obtain the patterns from the candidate set for the cultivation suggestions by considering the frequency weight and user＇s experience. In order to demonstrate the performance of our method in planting systems, we conduct a clicks-and-mortar cultivation platform, namely Eden Garden, for the elderly lifestyles of health and sustainability（LOHAS）. The experimental results show that the accuracy rate of our knowledge discovery method can reach up to 85%. Moreover, the results of the LOHAS index scale table present that the happiness of the elders is increasing while the elders are using our proposed method.

关键词： Elderly LOHAS fuzzy set heterogeneous datalifestyles of health and sustainability