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临床免疫学各论

The application of digital holography for accurate three-dimensional localisation of mosquito-bednet interaction

1984年

作者：（英）j.l.特克

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light(Advanced Manufacturing) 2022年第3期3卷 13-27页

作者： Matthew l Hall Katherine Gleave Angela hughes Philip j McCall Catherine E Towers David P Towers Optical Engineering Group School of EngineeringUniversity of WarwickCoventryCV47ALUK Vector Biology Department Liverpool School of Tropical MedicineLiverpoolL35QAUK

Understanding mosquito interaction with long-lasting insecticidal bednets is crucial in the development of more effective intervention methods to protect humans from malaria *** such,a 240×240×1000 mm laboratory setup for the in-line recording of digital holograms and subsequent in-focus reconstruction and 3D localisation of mosquitoes is *** bednet background removal methods are used to accurately localise a mosquito obscured by a bednet in 3D *** and physical data demonstrate that this method is suitable for mosquitoes positioned 3−1000 mm behind a bednet.A novel post-processing technique,involving a cascade-correlation of a Tamura of Intensity focus metric extracted from digitally reconstructed scenes,accurately localises mosquitoes positioned 35−100 mm behind a bednet from a single digital *** result of this study is a scalable digital holographic methodology to examine mosquito-bednet interaction in 3D at a level of accuracy previously only seen in 2D imaging of mosquitoes in a much smaller volume.

关键词： Digital Holography Metrology Entomology

MICROSTRUCTURE EVAlUATION OF SEMI-SOlID STEEl MATERIAlS IN ROllING PROCESS AND THE RESUlTING MECHANICAl PROPERTIES

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Acta Metallurgica Sinica(English letters) 2001年第5期14卷 347-351页

作者： R.B. Song, Y.l. Kang, j.l. Sun, A.M. Zhao and W.M. Mao School of Materials Science & Engineering, University of Science & Technology Beijing, Beijing 100083,China School of Materials Science & Engineering University of Science & Technology Beijing

The experimental study on the familiar 60Si2Mn and 1Cr18Ni9Ti materials rolled in the semi-solid state was carried out. Experimental results show that the segregation of liquid occurs when the semi-solid slurry is rolled, which influences the microstructure and mechanics performance of workpiece under room temperature. The globular solid particles can not present plastic deformation unless high solid fraction. At the same time, the mechanics property of workpiece is pretty good while the semi-solid slurry of 1Cr18Ni9Ti material is rolled by a pass and no other treatment.

关键词： Mechanical properties Microstructure Performance Rolling

原发性卵巢功能不全与卵巢早衰的病因学研究进展

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中华妇产科杂志 2008年第12期43卷 897-899页

作者：陈子江秦莹莹 Simpson j.l. 山东大学附属省立医院生殖医学中心济南250021 College of Medicine Miami Florida International University USA

目前，卵巢早衰（premature ovarian failure，POF）是被广泛接受和应用的专业术语，通常是指女性40岁之前闭经，伴有高卵泡刺激素（FSH）和低雌激素水平。由于临床治疗很棘手，如何预防和预测POF的发生风险，成为临床医生关注的焦点。... 详细信息

目前，卵巢早衰（premature ovarian failure，POF）是被广泛接受和应用的专业术语，通常是指女性40岁之前闭经，伴有高卵泡刺激素（FSH）和低雌激素水平。由于临床治疗很棘手，如何预防和预测POF的发生风险，成为临床医生关注的焦点。尽管在POF发病机制的探讨中，染色体结构或数目异常、自身免疫功能、医源性及环境等相关因素与POF发病的相关性研究已取得很大进展，但仍有部分POF患者的病因不清，称为“特发性POF”。

关键词：原发性卵巢功能不全卵巢早衰病因学低雌激素水平自身免疫功能发病机制卵泡刺激素 POF

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《感觉与可感物》选译

世界哲学 2009年第5期 43-71页

作者： j.l.奥斯汀[英] 陈嘉映(译) 不详首都师范大学哲学系中国现代思想文化研究所

感觉与料理论是个古老的哲学理论,20世纪上半叶更是极为流行,奥斯汀以艾耶尔的《经验知识之基础》为靶子,采用语言分析方法,对这一理论做出多方面的批判。奥斯汀指出,这一理论中包含了过度概括、虚假两分等常见的哲学谬误,以扭曲的方式... 详细信息

感觉与料理论是个古老的哲学理论,20世纪上半叶更是极为流行,奥斯汀以艾耶尔的《经验知识之基础》为靶子,采用语言分析方法,对这一理论做出多方面的批判。奥斯汀指出,这一理论中包含了过度概括、虚假两分等常见的哲学谬误,以扭曲的方式使用直接/间接、实在、真正的、看起来等一系列相关语词。奥斯汀还连带批判了当时甚为流行的"两种语言"理论。最后,奥斯汀指出,艾耶尔并非当真对感知问题感兴趣,他当真关心的是认识论,并且继承了一个重大的传统错误,即妄图确立不可能误错、不可能需要纠正的知识基础。

关键词：感觉与料理论感官感知错觉两种语言不可能误错

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论电视剧的特性

文艺研究 1989年第1期 174-175页

作者： j.l.斯蒂安李醒

对电视剧的评价,必须针对电视媒体的性质、针对它能做什么和不能做什么来进行衡量。电视剧与舞台剧相比,它所缺少的一个根本因素是舞台空间,没有它,戏的完整意义就不存在了。在舞台上,一个演员在环境中处于何种地位,他同其他演员在空间... 详细信息

对电视剧的评价,必须针对电视媒体的性质、针对它能做什么和不能做什么来进行衡量。电视剧与舞台剧相比,它所缺少的一个根本因素是舞台空间,没有它,戏的完整意义就不存在了。在舞台上,一个演员在环境中处于何种地位,他同其他演员在空间上的相互关系,尤其是演员同观众的空间关系,这些都会加深角色和观众之间的同情和理解,反应和共鸣。角色周围的舞台空间赋予了他个性特征,舞台剧平均有三堂景。电视剧的场景比舞台剧多几倍。

关键词：电视剧舞台剧舞台空间演员观众电视媒体个性特征相互关系空间关系根本因素

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移情与道德发展

Genomic resources for the brown planthopper, Nilaparvata lugens： Transcriptome pyrosequencing and microarray design

作者： (美)j.l.霍夫曼

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Insect Science 2012年第1期19卷 1-12页

作者： Chris Bass Martin Bay Hebsgaard joseph hughes Centre for Sustainable Pest and Disease Management Rothamsted Research Harpenden University of Edinburgh Institute of Evolutionary Biology Kings Buildings Edinburgh Institute of Biodiversity Animal Health and Comparative Medicine College of Medical Veterinary and Life Sciences University of Glasgow Glasgow United Kingdom

The brown planthopper, Nilaparvata lugens is a pest of cultivated rice through- out Asia and is controlled using insecticides and/or resistant rice varieties. This species has developed resistance to many classes of insecticide and biotypes have developed that are vir- ulent against formerly resistant rice cultivars. Insects use a suite of detoxification enzymes, including cytochrome P450s, glutathione S-transferases and carboxyl/cholinesterases to defend themselves against plant secondary metabolites and pesticides. Pyrosequencing on the Roche 454-FlX platform was used to produce a substantial expressed sequence tag （EST） dataset to complement the existing Sanger sequenced ESTs in GenBank. A total of 78 959 reads were combined with the 37 392 publically available Sanger ESTs; these assembled into 8 911 contigs and 10 620 singletons. Analysis of the distribution of tenta- tive unique genes （TUGs） with the gene ontology for biological processes and molecular functions suggests that the 454 and Sanger EST assembly is broadly representative of the N. lugens transcriptome. The brown planthopper transcriptome was found to contain 31 TUGs encoding P450s, nine encoding glutathione S-transferases and 26 encoding car- boxyl/cholinesterases and many of these are putatively involved in the detoxification of xenobiotics. The Agilent eArray platform was used to construct an oligonucleotide mi- croarray populated with probes for ~ 19 000 unigene sequences, including all those known to encode detoxification enzymes. The genomic resources developed in this study will be useful to the community studying this crop pest and will help elucidate the molecular mechanism underlying insecticide resistance and planthopper adaptation to resistant rice cultivars.

关键词： brown planthopper detoxification enzymes insecticide resistance Nilaparvata lugens transcriptome sequencing

Promising applications of D-amino acids in periprosthetic joint infection

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Bone Research 2023年第2期11卷 248-272页

作者： Matthew Caldwell Megan hughes Fei Wei Christopher Ngo Raven Pascua Abinaya Sindu Pugazhendhi Melanie j.Coathup Biionix Cluster&College of Medicine University of Central FloridaBlvdOrlandoFL32827USA School of Biosciences Cardiff UniversityCF103AT WalesUK Burnett School of Biomedical Sciences College of MedicineUniversity of Central Florida6900 Lake NonaBlvdOrlandoFL32827USA

Due to the rise in our aging population,a disproportionate demand for total joint arthroplasty(TjA)in the elderly is *** joint infection(PjI)represents one of the most challenging complications that can occur following TjA,and as the number of primary and revision TjAs continues to rise,an increasing PjI burden is *** advances in operating room sterility,antiseptic protocols,and surgical techniques,approaches to prevent and treat PjI remain difficult,primarily due to the formation of microbial *** difficulty motivates researchers to continue searching for an effective antimicrobial *** dextrorotatory-isoforms of amino acids(D-AAs)are essential components of peptidoglycan within the bacterial cell wall,providing strength and structural integrity in a diverse range of *** many tasks,D-AAs regulate cell morphology,spore germination,and bacterial survival,evasion,subversion,and adhesion in the host immune *** administered exogenously,accumulating data have demonstrated that D-AAs play a pivotal role against bacterial adhesion to abiotic surfaces and subsequent biofilm formation;furthermore,D-AAs have substantial efficacy in promoting biofilm *** presents D-AAs as promising and novel targets for future therapeutic *** their emerging antibacterial efficacy,their role in disrupting PjI biofilm formation,the disassembly of established TjA biofilm,and the host bone tissue response remains largely *** review aims to examine the role of D-AAs in the context of *** to date suggest that D-AA bioengineering may serve as a promising future strategy in the prevention and treatment of PjI.

关键词： prevention spite furthermore