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One-year status of hepatic venous pressure gradient measurement from 85 hospitals in china

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Portal Hypertension & Cirrhosis 2024年第2期3卷 116-123页

作者： Jitao Wang Ting Cui Linpeng Zhang Zhiping Yan Lei Li Jinjun Chen Junhui Sun Hua Xiang He Zhu Hao Wu Jiancuo Gengzang Feng Zhang wei Wu Guohong cao Wuhua Guo Haibin Shi Hui Xue Guangjun huang Qiang Yu Meng Niu Huiling Xiang Derun Kong wei Gou Xuefeng Luo Fuliang He Min Yuan wei Liu Yong Wang Hongjie Hu Xiaoli Zhu Tao Yu Qinxue Sun wei Qu Ting Lu Deqiang Ma Li Zhang Jun Ma Jun Yang Ketao Mu Xiaoliang Zhu Kai Xiong Huiguo Ding Shengjuan Yao Mingsheng huang Fang Wang Zexin Wang Yong huang Jianan Li Hongfeng Yi Birun huang Zhongwei Zhao Duiping Feng Yanming Lei Changlong Hou Wenbo Guo Shirong Liu Gaojun Teng Kangshun Zhu Fan Wu Xiaogang Hu Wenfeng Zhang Shaoqi Yang zhouchao Hu Pengfei Pang Shaowu Zhuang weidong Wang Qingliang Zhu Kunpeng Zhang Chengyu Liu Dongliang Li Chao Ma Hong Jiang Xingong Zhao weixin Ren Zhiwei Wang Lei Yu Fuhuang Lin Chaoguang Yan Feng Wang Lei Yu Hui Huan Wenyong Shen Shaofei He Chengda Zhang Jinlun Bao Jiangtao Liu Jun Wu Jianbo Zhao Jian Zhang Xiaolong Qi Hebei Provincial Key Laboratory of Cirrhosis&Portal Hypertension Xingtai People's HospitalXingtaiHebeiChina Center of Portal Hypertension Department of RadiologyZhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsuChina department of Interventional Therapy Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijingChina department of Intervention Taiyuan Third People's HospitalTaiyuanShanxiChina department of Intervention Zhongshan Hospital Affiliated to Fudan UniversityShanghaiChina department of Interventional Medicine The First Hospital of Lanzhou UniversityLanzhouGansuChina department of Infectious Diseases Nanfang Hospital of Southern Medical UniversityGuangzhouGuangdongChina Hepatobiliary and Pancreatic Intervention Center The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiangChina Interventional Vascular Surgery Hunan Provincial People's HospitalChangshaHunanChina department of Intervention Sixth People's Hospital of ShenyangShenyangLiaoningChina department of Gastroenterology West China Hospital of Sichuan UniversityChengduSichuanChina department of Intervention The Fourth People's Hospital of Qinghai ProvinceXiningQinghaiChina department of Gastroenterology Nanjing Drum Tower HospitalNanjingJiangsuChina department of Gastroenterology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina department of Radiology Shulan(Hangzhou)HospitalHangzhouZhejiangChina department of Intervention Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhouFujianChina department of Interventional Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsuChina department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxiChina department of Gastroenterology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinanShandongChina department of Interventional Radiology Fifth Medical Center

Aims:Surveys and research on the applications of the hepatic venous pressure gradient(HVPG)are important for understanding the current status and future development of this technology in *** article aimed to investigate the status of hepatic venous pressure gradient measurement in china in ***:We investigated the overall status of HVPG technology in china-including hospital distribution,hospital level,annual number of cases,catheters used,average cost,indications,and current challenges by using online *** counting the number and percentages of cases of these results,we hope to clarify the current status of HVPG measurements in ***:According to the survey,85 hospitals in china used HVPG technology in 2022 distributed across 29 provinces.A total of 4989 HVPG measurements were performed in all of the surveyed hospitals in 2022,of which 281. cases(56.4%)were measured *** average cost of HVPG measurement was 5646.8±2327.9 *** the clinical teams who performed the measurements(sometimes multiple per hospital),94.3%(82/87)used the balloon method,and the majority of the teams(72.4%,63/87)used embolectomy ***:This survey clarified the clinical application status of HVPG in china and confirmed that some medical institutions in china have established a foundation for this *** is still necessary to continue promoting and popularizing this technology in the future.

关键词： application status hepatic vein pressure gradient questionnaire survey

Glycolytic potential enhanced by blockade of pyruvate influx into mitochondria sensitizes prostate cancer to detection and radiotherapy

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Cancer Biology & Medicine 2022年第9期19卷 1315-1333页

作者： Huan Xu Junyi Chen Zhi cao Xi Chen Caihong {1. Jin Ji Yalong Xu Junfeng Jiang Yue Wang Guowang Xu Lina zhou Jingyi He Xuedong wei Jason Boyang Wu Zhong Wang Shancheng Ren Fubo Wang department of Urology Shanghai Changhai HospitalSecond Military Medical UniversityShanghai 200433China department of Urology Shanghai Ninth People’s HospitalShanghai 200011China department of Urology the Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000China department of Urology No.971 Hospital of the People’s Liberation Army NavyQingdao 266000China Center for Genomic and Personalized Medicine Guangxi Key Laboratory for Genomic and Personalized MedicineGuangxi Collaborative Innovation Center for Genomic and Personalized MedicineGuangxi Medical UniversityNanning 530021China Research Center of Developmental Biology Second Military Medical UniversityShanghai 200433China Dalian Institute of Chemical Physics Chinese Academy of SciencesDalian 116023China department of Urology the First Affiliated Hospital of Soochow UniversitySuzhou 215006China department of Pharmaceutical Sciences College of Pharmacy and Pharmaceutical SciencesWashington State UniversitySpokaneWA 99202USA

Objective:This study aimed to evaluate the effects of mitochondrial pyruvate carrier(MPC)blockade on the sensitivity of detection and radiotherapy of prostate cancer(PCa).Methods:We investigated glycolysis reprogramming and MPC changes in patients with PCa by using metabolic profiling,RNASeq,and tissue *** blockade of pyruvate influx into mitochondria was observed in cellular studies to detect its different effects on prostate carcinoma cells and benign prostate *** mouse models were injected with an MPC inhibitor to evaluate the sensitivity of 1.F-fluorodeoxyglucose positron emission tomography with computed tomography and radiotherapy of ***,the molecular mechanism of this different effect of transient blockage towards benign prostate cells and prostate cancer cells was studied in ***:MPC was elevated in PCa tissue compared with benign prostate tissue,but decreased during cancer *** transient blockade increased PCa cell proliferation while decreasing benign prostate cell proliferation,thus increasing the sensitivity of PCa cells to 1.F-PET/CT(SUVavg,P=0.01.;SUVmax,P=0.03)and radiotherapy(P1..This differential effect of MPC on PCa and benign prostate cells was dependent on regulation by a VDAC1.MPC-mitochondrial homeostasis-glycolysis ***:Blockade of pyruvate influx into mitochondria increased glycolysis levels in PCa but not in non-carcinoma prostate *** transient blockage sensitized PCa to both detection and radiotherapy,thus indicating that glycolytic potential is a novel mechanism underlying PCa *** change in the mitochondrial pyruvate influx caused by transient MPC blockade provides a critical target for PCa diagnosis and treatment.

关键词： Glycolytic potential prostate cancer mitochondrial pyruvate carrier(MPC) mitochondria pyruvate influx diagnosis radiotherapy

Variations in length of stay among survived very preterm infants admitted to Chinese neonatal intensive care units

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World Journal of Pediatrics 2022年第2期18卷 126-134页

作者： Min Zhang Yan-Chen Wang Jin-Xing Feng Ai-Zhen Yu Jing-wei {1. Si-Yuan Jiang Xin-Yue Gu Jian-Hua Sun Yun cao Wen-Hao zhou Shoo KLee Li-Li Wang Rong Yin Division of Neonatology The First Affiliated Hospital of Anhui Medical UniversityNo.218Jixi RoadShushan DistrictHefei 230022China NHC Key Laboratory of Neonatal Diseases Fudan UniversityChildren's Hospital of Fudan UniversityShanghai 201102China Division of Neonatology Shenzhen Children's HospitalShenzhen 518038China Division of Neonatology.Children's Hospital of Fudan university 399 Wanyuan RoadMinhang DistrictShanghai 201102China Division of Neonatology Shanghai Children's Medical CenterShanghai Jiao Tong University School of MedicineShanghai 200127China Maternal-Infants Care Research Centre and department of Pediatrics Mount Sinai HospitalTorontoON M5G 1X5.Canada Professor Emeritus University of Toronto.TorontoON M5T 3M7Canada

Background This study aimed to describe length of stay(LOS)to discharge and site variations among very preterm infants(VPIs)admitted to 57 Chinese neonatal intensive care units(NICUs)and to investigate factors associated with LOS for *** This retrospective multicenter cohort study enrolled all infants2 weeks’gestation and admitted to 57 NICUs which had participated in the Chinese Neonatal Network,within 7 days after birth in *** criteria included major congenital anomalies,NICU deaths,discharge against medical advice,transfer to non-participating hospitals,and missing discharge *** multivariable linear models were used to estimate the association of infant characteristics and *** A total of 6580 infants were included in our *** overall median LOS was 46 days[interquartile range(IQR):35-60],and the median corrected gestational age at discharge was 36 weeks(IQR:35-38).LOS and corrected gestational age at discharge increased with decreasing gestational *** median corrected gestational age at discharge for infants at 24 weeks,25 weeks,26 weeks,27-28 weeks,and 29-31.weeks were 41.weeks,39 weeks,38 weeks,37 weeks and 36 weeks,*** site variation of LOS was identified with observed median LOS from 33 to 71.days in different *** The study provided concurrent estimates of LOS for VPIs which survived in Chinese NICUs that could be used as references for medical staff and *** variation of LOS independent of infant characteristics existed,indicating variation of care practices requiring further investigation and quality improvement.

关键词： Length of stay to discharge home Neonatal intensive care Preterm Risk factors

儿童自身免疫性多内分泌腺病综合征Ⅰ型2例并文献复习

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安徽医药 2024年第9期28卷 1871-1875页

作者：郝会民李杨世玉黄爱刘晓景曹冰燕卫海燕郑州大学附属儿童医院、河南省儿童医院、郑州儿童医院内分泌遗传代谢科河南郑州450018 国家儿童医学中心、首都医科大学附属北京儿童医院内分泌遗传代谢科北京100045

目的探讨儿童自身免疫性多内分泌腺病综合征Ⅰ型(APS-Ⅰ)临床特征及AIRE基因变异。方法回顾分析河南省儿童医院201.年5—1.月收治的2例APS-Ⅰ病儿临床资料,并复习相关文献,对已报道中国儿童APS-Ⅰ临床表型及基因型进行总结。结果2例男性... 详细信息

目的探讨儿童自身免疫性多内分泌腺病综合征Ⅰ型(APS-Ⅰ)临床特征及AIRE基因变异。方法回顾分析河南省儿童医院201.年5—1.月收治的2例APS-Ⅰ病儿临床资料,并复习相关文献,对已报道中国儿童APS-Ⅰ临床表型及基因型进行总结。结果2例男性APS-Ⅰ病儿,病例1.1.岁,3岁慢性念珠菌感染,1.岁重度贫血;病例2,1.岁,7岁甲状旁腺功能减退,8岁慢性念珠菌感染,1.岁肾上腺皮质功能减退症和重度贫血。高通量测序提示AIRE基因变异,病例1.c.44G>A(p.R1.H)和c.1.36C>T(p.Q346*)杂合突变,病例2为c.38T>C(p.L1.P)和c.1.00+2T>C杂合突变,其中c.1.36C>T(p.Q346*)和c.1.00+2T>C为HGMD及ClinVar数据库未报道过的变异位点,经美国人类遗传学和基因组学医学学会(ACMG)指南评估分别为疑似致病及致病变异。2例病儿给予药物治疗后临床症状缓解。分别检索PubMed、万方和CNKI数据库,共检索到22例确诊为APS-Ⅰ中国病儿,包括本研究2例,共24例,其中1.例基因诊断,有1.种基因变异,无热点变异,9例临床诊断。结论新的变异位点扩大了AIRE基因变异谱,APS-Ⅰ临床表现多样,且出现时间跨度大,相关抗体及AIRE基因检测有助于疾病早期诊断,多学科诊疗提供个体化的治疗策略。

关键词：多内分泌腺疾病,自身免疫性 AIRE基因念珠菌病,慢性黏膜皮肤甲状旁腺功能减退症肾上腺皮质功能减退症

To explore the efficacy of Vm26 combined with MeCCNU therapy for the low-grade gliomas

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To explore the efficacy of Vm26 combined with MeCCNU therapy...

Two-Dimensional Metal-Organic Frameworks with Unique Oriented Layers for Oxygen Reduction Reaction:Tailoring the Activity through Exposed Crystal Facets

中国抗癌协会神经肿瘤专业委员会第八届学术会议

作者： cao guang-hui,TAN {1.-guo,FENG ming,SHEN hao,WANG jun-xiang,huang yu-lun,zhou You-xin.department of Neurosurgery & Brain and Nerve Reseach Laboratory,The First Affiliated Hospital of Soochow university,Suzhou 21.006,china

Objective To explore the efficacy of Vm26 combined with MeCCNU therapy for the low-grade MGMT-positive gliomas after tumor resection and *** The clinical data of 22 patients with MGMT-positive grade Ⅱ gliomas who underwent total removal of tumors with enhanced MRI imaging showing no residual tumors in the neurosurgery of the first affiliated hospital of Soochow university from Jan 2005 to Oct 2008 were analyzed retrospectively.1. cases of all 22 patients are diffuse astrocytomas;3 cases are oligodendrogliomas;5 cases are mixed oligo-astrocytomas and 4 cases are *** patients received three-dimensional conformal radiotherapy 2～4 weeks after surgery with radiation field including areas 1.2cm away from the edge of cavity after tumor resection according to brain imaging and exposure dose being 50～55Gy/6～7weeks.2 weeks after the end of radiotherapy,these patients underwent Vm26 combined with MeCCNU therapy（Vm26:50mg/m2/day,intravenous dripping for 3 days,repeated after 8 weeks for 3 cycles;MeCCNU:50mg/m2/day,taken orally for 3 days,repeated after 8 weeks for 4 cycles） with MRI scanning *** 6 cases of 22 MGMT-positive grade Ⅱ gliomas are positive for both TopoⅡα and Pgp;1. cases and 2 cases are only positive for TopoⅡα and Pgp,respectively;and 4 cases are negative for both TopoⅡα and Pgp.22 patients were followed up for 2～5 years and tumors recurred in 6 cases with average time of recurrence being 1..6 months;CT or MRI imaging showed no tumor recurrence in 1. cases;3 cases underwent the second surgery due to MRI imaging showing possible tumor recurrence 2 years after prior surgery;however,pathological examination reported suspected recurring tumor was necrotic *** these 22 patients,1.year survival rate was 1.0% and 2-year survival rate was 88.9%.Conclusion Vm26 combined with MeCCNU chemotherapy is able to efficaciously inhibit the growth of gliomas,have little side-effects,and is a safe and effective therapeutic alternative

关键词： brain tumor glioma chemotherapy

来源： cnki会议评论

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CCS Chemistry 2022年第5期4卷 1633-1642页

作者： Yanzhi Wang Tu Sun Amir H.B.Mostaghimi Tiago J.Goncalves Zuozhong Liang Yuye zhou {1. Zhang Zhehao huang Yanhang Ma Rui cao Samira Siahrostami Haoquan Zheng Key Laboratory of Applied Surface and Colloid Chemistry Ministry of EducationSchool of Chemistry and Chemical EngineeringShaanxi Normal UniversityXi’an 710119 School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210 department of Chemistry University of CalgaryCalgaryAB T2N 1N4 School of Engineering Sciences in Chemistry Biotechnologyand HealthDepartment of ChemistryDivision of Applied Physical ChemistryAnalytical ChemistryKTH Royal Institute of TechnologySE-10691 Stockholm department of Materials and Environmental Chemistry Stockholm UniversitySE-10691 Stockholm

As one of the most important families of porous materials,metal–organic frameworks(MOFs)have well-defined atomic *** provides ideal models for investigating and understanding the relationships between structures and catalytic activities at the molecular ***,the active sites on the edges of two-dimensional(2D)MOFs have rarely been studied,as they are less exposed to the ***,for the first time,we synthesized and observed that the 2D layers could align perpendicular to the surface of a 2D zeolitic imidazolate framework L(ZIF-L)with a leaf-like *** to this unique orientation,the active sites on the edges of the 2D crystal structure could mostly be exposed to the ***,when another layer of ZIF-L-Co was grown heteroepitaxially onto ZIF-L-Zn(ZIF-L-Zn@ZIF-L-Co),the two layers shared a common b axis but rotated by 90°in the ac *** demonstrated that we could control exposed facets of the 2D *** ZIF-L-Co with more exposed edge active sites exhibited high electrocatalytic activity for oxygen reduction *** work provides a new concept of designing unique oriented layers in 2D MOFs to expose more edge-active sites for efficient electrocatalysis.

关键词： unique oriented layer two-dimensional material metal-organic framework electrocatalyst oxygen reduction reaction

Surgical treatment for both-column acetabular fractures using pre-operative virtual simulation and three-dimensional printing techniques

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Chinese Medical Journal 2020年第4期133卷 395-401页

作者： Ji-Hui huang Hui Liao Xin-Yu Tan {1.-Rong Xing Qi zhou Yu-Shi Zheng Hong-Yu cao Can-Jun Zeng department of Orthopedics The Third Affiliated Hospital of Southern Medical UniversityGuangzhouGuangdong 510630China Southern Medical university GuangzhouGuangdong 510515China Musculoskeletal Disease Center Jerry L.Pettis Memorial Veterans Affairs Medical CenterLoma LindaCA 92357USA department of Medicine Loma Linda UniversityLoma LindaCA 92354USA

Background:Surgical treatment of both-column acetabular fractures is challenging because of the complex acetabular fracture patterns and the curved surface of the *** study has compared the application of three-dimensional(3D)printing technology and traditional methods of contouring plates intra-operatively for the surgical treatment of both-column acetabular *** presented the use of both 3D printing technology and a virtual simulation in pre-operative planning for both-column acetabular *** hypothesized that 3D printing technology will assist orthopedic surgeons in shortening the surgical time and improving the clinical ***:Forty patients with both-column acetabular fractures were recruited in the randomized prospective case-control study from September 201. to September 201. for this prospective study(***1.00028230).We allocated the patients to two groups using block randomization(3D printing group,n=20;conventional method group,n=20).For the 3D printing group,1.1.scaled pelvic models were created using 3D printing,and the plates were pre-contoured according to the pelvic *** plates for the conventional method group were contoured during the operation without 3D printed pelvic *** operation time,instrumentation time,time of intra-operative fluoroscopy,blood loss,number of times the approach was performed,blood transfusion,post-operative fracture reduction quality,hip joint function,and complications were recorded and compared between the two ***:The operation and instrumentation times in the 3D printing group were significantly shorter(1.0.8±29.2 min,t=-7.5,P1.and 32.1.9.5 min,t=-6.5,P1.respectively)than those in the conventional method *** amount of blood loss and blood transfusion in the 3D printing group were significantly lower(500[400,800]mL,Mann-Whitney U=74.5,P1.and 0[0,400]mL,Mann-Whitney U=59.5,P1.respectively)than those in the conventional method group.T

关键词： Both-column Acetabulum fractures Computer simulation Three-dimensional printing Internal fracture fixation

STCF conceptual design report (Volume 1.: Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai L.P.An R.Aliberti Q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.H.Bu F.M.Cai H.Cai J.J.cao Q.H.cao X.cao Z.cao Q.Chang K.T.Chao D.Y.Chen H.Chen H.X.Chen J.F.Chen K.Chen L.L.Chen P.Chen S.L.Chen S.M.Chen S.Chen S.P.Chen W.Chen X.Chen X.F.Chen X.R.Chen Y.Chen Y.Q.Chen H.Y.Cheng J.Cheng S.Cheng T.G.Cheng J.P.Dai L.Y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du Z.G.Du L.M.Duan D.Epifanov Y.L.Fan S.S.Fang Z.J.Fang G.Fedotovich C.Q.Feng X.Feng Y.T.Feng J.L.Fu J.Gao Y.N.Gao P.S.Ge C.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong B.Gou W.Gradl J.L.Gu A.Guevara L.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo Y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han M.Han X.Q.Hao J.B.He S.Q.He X.G.He Y.L.He Z.B.He Z.X.heng B.L.Hou T.J.Hou Y.R.Hou C.Y.Hu H.M.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.C.Hu J.Hua G.S.huang J.S.huang M.huang Q.Y.huang W.Q.huang X.T.huang X.J.huang Y.B.huang Y.S.huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia H.B.Jiang J.Jiang S.Z.Jiang J.B.Jiao Z.Jiao H.J.Jing X.L.Kang X.S.Kang B.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev C.H.Li C.Li D.Y.Li F.Li G.Li G.Li H.B.Li H.Li H.N.Li H.J.Li H.L.Li J.M.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li S.Li T.Li W.J.Li X.Li X.H.Li X.Q.Li X.H.Li Y.Li Y.Y.Li Z.J.Li H.Liang J.H.Liang Y.T.Liang G.R.Liao L.Z.Liao Y.Liao C.X.Lin D.X.Lin X.S.Lin B.J.Liu C.W.Liu D.Liu F.Liu G.M.Liu H.B.Liu J.Liu J.J.Liu J.B.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.B.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long C.G.Lu J.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.J.Luo T.Luo X.F.Luo Y.H.Luo H.J.Lyu X.R.Lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko Z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng L.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian C.F.Qiao J.J.Qin J.J.Qin L.Q.Qin X.S.Qin T.L.Qiu J.Rademacker C.F.Redmer H.Y.Sang Anhui university Hefei 230039China Beihang university Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central china Normal {1. Wuhan 430079China Central South university Changsha 410083China china {1. of Geosciences Wuhan 430074China china {1. of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(EPFL) LausanneSwitzerland Fudan university Shanghai 200433China Goethe university Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal university Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal university Shijiazhuang 050024China Hebei university Baoding 071002China Hefei university of Technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal university Xinxiang 453007China Henan university Kaifeng 475004China High Energy Physics Center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 1. Pokrovsky Bulvar Moscow 109028Russia huangshan {1. Huangshan 245000China Hubei university of Automotive Technology Shiyan 442002China Hunan Normal university Changsha 410081China Hunan university of Science and Technology Xiangtan 411201China Hunan university Changsha 410082China Indiana university BloomingtonIndiana 47405USA Inner Mongolia university Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin university Changch

The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×1.^(35) cm^(–2)·s^(–1. or *** STCF will produce a data sample about a factor of 1.0 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STCF project in china is under development with an extensive R&D *** document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STCF detector conceptual design

融化和冻结状态下土及混凝土/土界面剪切特性试验研究

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中南大学学报（自然科学版） 2021年第11期52卷 4137-4147页

作者：黄旭斌周恒狄圣杰盛煜彭尔兴张玺彦曹伟中国科学院西北生态环境资源研究院冻土工程国家重点实验室甘肃兰州730000 中国电建集团西北勘测设计研究院有限公司陕西西安710065 中国科学院大学北京100049

为了研究融化和冻结状态下土及结构/土界面的剪切力学特性,采用直剪试验的方法,对不同温度条件下土以及不同温度、含水率条件下混凝土/土界面开展试验研究。基于试验结果,分析在上拔荷载作用下桩-土界面的破坏机理,并探讨不同规范中切... 详细信息

为了研究融化和冻结状态下土及结构/土界面的剪切力学特性,采用直剪试验的方法,对不同温度条件下土以及不同温度、含水率条件下混凝土/土界面开展试验研究。基于试验结果,分析在上拔荷载作用下桩-土界面的破坏机理,并探讨不同规范中切向冻胀力取值问题。研究结果表明:融化状态下土及混凝土/土界面剪切应力曲线为应变硬化型,冻结状态下为应变软化型;无论是在融化还是冻结状态下,土的抗剪强度均比混凝土/土界面的抗剪强度大。融化状态下混凝土/土界面的黏聚力随含水率增大而增大,内摩擦角随含水率增大而减小;在冻结状态下,温度每降低1.,黏聚力增大33.26~1.9.28 k Pa(含水率从1.%增至35%),含水率每增加1.,黏聚力增大7.61.25.90 kPa(温度从-1.降至-5℃)。

关键词：融化和冻结状态直剪试验混凝土/土界面抗剪强度