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Flexible capacitive pressure sensor based on interdigital electrodes with porous microneedle arrays for physiological signal monitoring

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Nanotechnology and Precision Engineering 2024年第1期7卷 18-31页

作者： Jiahui Xu Minghao Wang Minyi Jin Siyan Shang Chuner Ni yili hu Xun Sun Jun Xu Bowen Ji Le Li Yuhua Cheng Gaofeng Wang School of Electronics&Information MOE Engineering Research Center of Smart Microsensors and MicrosystemsHangzhou Dianzi UniversityHangzhou 310018China Wenzhou Institute of Hangzhou Dianzi University Wenzhou 310018China Key Laboratory of Intelligent Operation and Maintenance Technology&Equipment for Urban Rail Transit of Zhejiang Province College of EngineeringInstitute of Precision Machinery and Smart StructureZhejiang Normal UniversityJinhua 321004China Institute of Guizhou Aerospace Measuring and Testing Technology Guiyang 550009China Unmanned System Research Institute Northwestern Polytechnical UniversityXi’an 710072China Research&Development Institute of Northwestern Polytechnical University in Shenzhen Shenzhen 518057China

Flexible pressure sensors have many potential applications in the monitoring of physiological signals because of their good biocompatibil-ity and ***,their relatively low sensitivity,linearity,and stability have hindered their large-scale commercial ***,aﬂexible capacitive pressure sensor based on an interdigital electrode structure with two porous microneedle arrays(MNAs)is *** porous substrate that constitutes the MNA is a mixed product of polydimethylsiloxane and *** to its porous and interdigital structure,the maximum sensitivity(0.07 kPa-1)of a porous MNA-based pressure sensor was found to be seven times higher than that of an imporous MNA pressure sensor,and it was much greater than that of aﬂat pressure sensor without a porous MNA ***-element analysis showed that the interdigital MNA structure can greatly increase the strain and improve the sensitivity of the *** addition,the porous MNA-based pressure sensor was found to have good stability over 1500 loading cycles as a result of its bilayer parylene-enhanced conductive electrode *** importantly,it was found that the sensor could accurately monitor the motion of aﬁnger,wrist joint,arm,face,abdomen,eye,and Adam’s ***,preliminary semantic recognition was achieved by monitoring the movement of the Adam’s ***,multiple pressure sensors were integrated into a 33 array to detect a spatial pressure distribu-×*** to the sensors reported in previous works,the interdigital electrode structure presented in this work improves sensitivity and stability by modifying the electrode layer rather than the dielectric layer.

关键词： Capacitive pressure sensor Microneedle array Porous PDMS Interdigital electrode

Target height and multipath attenuation joint estimation with complex scenarios for very high frequency radar

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Frontiers of Information Technology & Electronic Engineering 2022年第6期23卷 937-949页

作者： Sheng CHEN Yongbo ZHAO yili hu Chenghu CAO Xiaojiao PANG National Laboratory ofRadar Signal Processing Xidian UniversityXi'an710071China

Low-angle estimation for very high frequency(VHF)radar is a difficult problem due to the multipath effect in the radar field,especially in complex scenarios where the reflection condition is *** deal with this problem,we propose an algorithm of target height and multipath attenuation joint *** amplitude of the surface reflection coefficient is estimated by the characteristic of the data itself,and it is assumed that there is no reflected signal when the amplitude is very *** phase of the surface reflection coefficient and the phase difference between the direct and reflected signals are searched as the same part,and this represents the multipath phase *** Cramer-Rao bound of the proposed algorithm is also ***,computer simulations and real data processing results show that the proposed algorithm has good estimation performance under complex scenarios and works well with only one snapshot.

关键词： Low-angle estimation Very high frequency(VHF)radar Complex scenarios Multipath effect Height estimation

基于Hadamard product优化多层神经网络的胸部电阻抗成像研究

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生物医学工程学杂志 2024年第3期41卷 439-446,454页

作者：宋振忠李建平温建明万嫩马继杰张昱胡意立高增锋浙江师范大学工学院浙江省城市轨道交通智能运维技术与装备重点实验室精密机械与智能结构研究所浙江金华321004 千叶大学融合理工学府日本千叶263-8522

电阻抗成像(EIT)是一种无辐射、非侵入式的可视化诊断技术。为提高胸部电阻抗成像技术重建算法的成像分辨率和去伪影能力,本研究提出了一种利用Hadamard product优化多层神经网络(MANN)的HMANN算法。将HMANN算法的重建图像与广义矢量模... 详细信息

电阻抗成像(EIT)是一种无辐射、非侵入式的可视化诊断技术。为提高胸部电阻抗成像技术重建算法的成像分辨率和去伪影能力,本研究提出了一种利用Hadamard product优化多层神经网络(MANN)的HMANN算法。将HMANN算法的重建图像与广义矢量模式匹配(GVSPM)算法、截断奇异值分解(TSVD)算法、反向传播(BP)神经网络算法和传统MANN算法的重建图像进行对比,仿真结果表明:相对于MANN算法,HMANN算法重建图像的相关系数在圆截面模型中可以提高17.30%,在肺截面模型中可以提高13.98%。虽然肺截面模型中HMANN算法重建图像的部分相关系数会有所下降,但在所有模型中,HMANN算法保留了MANN算法的图像信息,同时HMANN算法重建图像的伪影更少,检测目标与背景的可识别度比传统MANN算法高。本研究可以提升重建图像的相关系数,有效去除重建图像的伪影,为EIT成像技术提供了一种有效提升重建图像质量的新思路。

关键词：电阻抗成像多层神经网络 Hadamardproduct 伪影

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自拟润肺止咳汤联合2HRZE/4HR方案治疗肺阴亏损型肺结核临床观察

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中国中医药现代远程教育 2024年第16期22卷 126-129页

作者：胡贤琪唐青云黎胜胡益利张小燕江西省上犹县结核病防治所结核科江西赣州341200 江西省上犹县人民医院感控科江西赣州341200 江西省上犹县人民医院内科江西赣州341200 江西省上犹县人民医院中医科江西赣州341200 江西省上犹县结核病防治所公共卫生科江西赣州341200

目的观察自拟润肺止咳汤联合抗痨方案(2HRZE/4HR)治疗肺阴亏损型肺结核的临床效果。方法选取上犹县结核病防治所和上犹县人民医院2021年7月—2022年7月收治的80例肺阴亏损型肺结核患者,按照随机数字表法分为研究组40例和对照组40例,对... 详细信息

目的观察自拟润肺止咳汤联合抗痨方案(2HRZE/4HR)治疗肺阴亏损型肺结核的临床效果。方法选取上犹县结核病防治所和上犹县人民医院2021年7月—2022年7月收治的80例肺阴亏损型肺结核患者,按照随机数字表法分为研究组40例和对照组40例,对照组采用2HRZE/4HR方案治疗,研究组在此基础上联用自拟润肺止咳汤,对比两组治疗效果。结果研究组治疗总有效率为95.00%(35/40),高于对照组的52.50%(21/40)(P<0.05)。治疗后,研究组中医证候积分较对照组更低(P<0.05),咳嗽症状积分表(CSS)积分较对照组更低(P<0.05),莱切斯特生活质量问卷调查表(LCQ)评分较对照组更高(P<0.05)。结论自拟润肺止咳汤联合2HRZE/4HR方案能够显著改善肺阴亏损型肺结核患者的临床病症,改善其生活质量,提高患者治疗依从性。

关键词：肺痨肺结核肺阴亏损证润肺止咳汤抗痨方案

Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia

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Acta Pharmaceutica Sinica B 2023年第2期13卷 598-617页

作者： Yin Feng Yefan Han Anni hu Yi Qu yili hu Hao Wu Xinzhi Wang Li He College of Pharmacy Nanjing University of Chinese MedicineNanjing 210046China China Jiangsu Key Laboratory of Research and Development in Marine Bio-resource Pharmaceutics Nanjing 210046China Experiment Center for Science and Technology Nanjing University of Chinese MedicineNanjing 210046China Department of Hematology Zhongnan Hospital of Wuhan UniversityWuhan 430071China

Although NPM1 mutations are frequently found in acute myeloid leukemia patients,therapeutic strategies are scarce and unsuitable for those who cannot tolerate intensive *** we demonstrated that heliangin,a natural sesquiterpene lactone,exerts favorable therapeutic responses in NPM1 mutant acute myeloid leukemia cells,with no apparent toxicity to normal hematogenous cells,by inhibiting their proliferation,inducing apoptosis,causing cell cycle arrest,and promoting ***-depth studies on its mode of action using quantitative thiol reactivity platform screening and subsequent molecular biology validation showed that the ribosomal protein S2(RPS2)is the main target of heliangin in treating NPM1 mutant *** covalent binding to the C222 site of RPS2,the electrophilic moieties of heliangin disrupt pre-rRNA metabolic processes,leading to nucleolar stress,which in turn regulates the ribosomal proteins-MDM2-p53 pathway and stabilizes *** data shows that the pre-rRNA metabolic pathway is dysregulated in acute myeloid leukemia patients with the NPM1 mutation,leading to a poor *** found that RPS2 plays a critical role in regulating this pathway and may be a novel treatment *** findings suggest a novel treatment strategy and lead compound for acute myeloid leukemia patients,especially those with NPM1 mutations.

关键词： Acute myeloid leukemia Heliangin NPM1-mutation Differentiation Pre-rRNA Covalent RPS2 p53 stabilization

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基于多视角时间特征的短期电力负荷预测

电工技术 2024年第11期 19-25,32页

作者：李波罗清高翔陈祖秀胡屹立云南电网有限责任公司电力科学研究院云南昆明650100 云南电网有限责任公司玉溪供电局云南玉溪653100

外部因素对电力负荷具有周期性影响,且这些影响直接反映在电力负荷值上。基于多视角表示学习思想,使用历史电力负荷预测值的不同视角作为外部因素的隐藏表示。通过对历史电力负荷数据进行特征提取,并将电力负荷分为分钟、小时和天三个... 详细信息

外部因素对电力负荷具有周期性影响,且这些影响直接反映在电力负荷值上。基于多视角表示学习思想,使用历史电力负荷预测值的不同视角作为外部因素的隐藏表示。通过对历史电力负荷数据进行特征提取,并将电力负荷分为分钟、小时和天三个时间视角,分别采用了适应性的神经网络模型进行特征提取,并引入了一个多视角特征合并模块,融合不同时间尺度上的信息来提高负荷预测准确性。实验证明,所提出的方法在西南某地区的电力负荷数据集上表现出较好的预测性能,与单一时间视角的模型相比,平均绝对误差和均方误差分别降低了12.21%和11.12%。

关键词：短期电力负荷预测多视角时间特征多特征融合

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富硒核桃挂面的配方工艺优化及硒含量分析

食品科技 2024年第4期49卷 1-9页

作者：童宇航郑涵予游如梦胡依黎陈小玲程水源张绍鹏武汉轻工大学国家富硒农产品加工技术研发专业中心湖北省绿色富硒农产品精深加工工程技术研究中心湖北武汉430023 武汉轻工大学硒科学与工程现代产业学院湖北武汉430040 武汉轻工大学生命科学与技术学院湖北武汉430023

以小麦粉和富硒核桃粉为主要原料制作富硒核桃挂面,以挂面的蒸煮特性为评价标准,优化挂面加工过程中核桃粉配方的添加工艺;并以感官评价和核桃挂面的硒含量为分析指标,通过单因素试验评价分析和面时间、醒发时间、压延次数以及干燥温度... 详细信息

以小麦粉和富硒核桃粉为主要原料制作富硒核桃挂面,以挂面的蒸煮特性为评价标准,优化挂面加工过程中核桃粉配方的添加工艺;并以感官评价和核桃挂面的硒含量为分析指标,通过单因素试验评价分析和面时间、醒发时间、压延次数以及干燥温度对感官评价及核桃挂面硒含量的影响,进一步通过响应面分析确定最优加工工艺。结果表明:当富硒核桃粉的最优添加量为4%~6%、和面时间5 min、醒面时间31 min、压延次数为6次、干燥温度45℃时,得到的富硒核桃面条的营养价值高,蒸煮损失率小,有嚼劲,富有弹性,且硒含量损失率最低(15.50%)。

关键词：富硒核桃挂面加工工艺响应面法

Short-range clutter suppression method combining oblique projection and interpolation in airborne CFA radar

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Journal of Systems Engineering and Electronics 2021年第1期32卷 92-102页

作者： hu yili ZHAO Yongbo PANG Xiaojiao CHEN Sheng National Laboratory of Radar Signal Processing Xidian UniversityXi’an 710071China

The airborne conformal array(CFA)radar's clutter ridges are range-modulated,which result in a bias in the estimation of the clutter covariance matrix(CCM)of the cell under test(CUT),further,reducing the clutter suppression performance of the airborne CFA *** clutter ridges can be effectively compensated by the space-time separation interpolation(STSINT)method,which costs less computation than the space-time interpolation(STINT)method,but the performance of interpolation algorithms is seriously affected by the short-range clutter,especially near the platform *** distributions of CFA are free,which yields serious impact that range spaces of steering vector matrices are non-orthogonal complement and even no longer ***,a new method is proposed that the shortrange clutter is pre-processed by oblique projection with the intersected range spaces(OPIRS),and then clutter data after being pre-processed are compensated to the desired range bin through the STSINT *** OPIRS also has good compatibility and can be used in combination with many existing *** the same time,oblique projectors of OPIRS can be obtained in advance,so the proposed method has almost the same computational load as the traditional compensation *** addition,the proposed method can perform well when the channel error *** simulation results verify the effectiveness of the proposed method.

关键词： airborne conformal arrays(CFA)radar oblique projection intersected range space short-range clutter suppression

三纬组合全显结构起始点位置设置对织物显色的影响

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纺织学报 2023年第4期44卷 78-85页

作者：胡伊丽周赳浙江理工大学浙江省丝绸与时尚文化研究中心浙江杭州310018

为探究三纬组合全显结构中起始点位置设置影响织物结构显色效果的内在规律,采用不同的起始点位置设计三纬组合全显结构,并研究其结构显色的特征。以16枚3飞纬面缎纹为基础组织,设置4种不同组织点分布特征的基础组织起始点位置,来设计三... 详细信息

为探究三纬组合全显结构中起始点位置设置影响织物结构显色效果的内在规律,采用不同的起始点位置设计三纬组合全显结构,并研究其结构显色的特征。以16枚3飞纬面缎纹为基础组织,设置4种不同组织点分布特征的基础组织起始点位置,来设计三纬组合全显结构,并形成4组三纬组合结构组织库,再通过色卡设计、织造和测色分析,获得结构显色的色彩数据,并比较分析显色特征与组织结构。结果表明:三纬组合全显结构中显色纬浮长的位置变化是显色突变的根本原因,且起始点位置设置所引起的密集经浮长会影响织物显色的饱和度与织纹斜向的明显度,同时发现采用组织点分布均匀的基础组织起始点位置,具有较均匀的织物渐变显色效果。本研究结果可为三纬组合全显提花织物的数码化优化设计提供技术参考。

关键词：提花织物组织结构全显技术组织组织起始点优选设计