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Characterization of focal hypermetabolic thyroid incidentaloma: An analysis with F-18 fluorodeoxyglucose positron emission tomography/computed tomography parameters

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World Journal of Clinical Cases 2022年第1期10卷 155-165页

作者： Haejun Lee Yoo Seung Chung Joon-Hyop Lee Ki-young Lee Kyung-hoon Hwang Department of Nuclear Medicine Gachon University College of MedicineGil Medical CenterIncheon 21565South Korea Department of Endocrine Surgery Gachon University College of MedicineGil Medical CenterIncheon 21565South Korea Department of Endocrinology and Metabolism Gachon University College of MedicineGil Medical CenterIncheon 21565South Korea

BACKGROUND Incidentally found thyroid tumor(thyroid incidentaloma,TI)on F-18 fluorodeoxyglucose(FDG)positron emission tomography-computed tomography(PETCT)is reported in 2.5%-5%of patients being investigated for non-thyroid *** to 50%of these cases have been diagnosed to be malignant by cytological/histological ***(US)and fine-needle aspiration cytology are recommended for thyroid nodules with high FDG uptake(hypermetabolism)that are 1 cm or greater in *** is important to accurately determine whether a suspicious hypermetabolic TI is malignant or *** To distinguish malignant hypermetabolic TIs from benign disease by analyzing F-18 FDG PET-CT parameters and to identify a cut-off *** Totally,12761 images of patients who underwent F-18 FDG PET-CT for nonthyroid purposes at our hospital between January 2016 and December 2020 were retrospectively reviewed,and 339 patients[185 men(mean age:68±11.2)and 154 women(mean age:63±15.0)]were found to have abnormal,either focal or diffuse,thyroid FDG *** a thorough review of their medical records,US,and cytological/histological reports,46 eligible patients with focal hypermetabolic TI were included in this *** TIs were categorized as malignant and benign according to the cytological/histological reports,and four PET parameters[standardized uptake value(SUV)max,SUV_(peak),SUV_(mean),and metabolic tumor volume(MTV)]were measured on FDG *** lesion glycolysis(TLG)was calculated by multiplying the SUV_(mean) by *** parametric and non-parametric methods were used to compare the five parameters between malignant and benign *** operating characteristic(ROC)curve analysis was performed to identify a cut-off *** Each of the 46 patients[12 men(26.1%;mean age:62±13.1 years)and 34 women(73.9%;mean age:60±12.0 years)]with focal hypermetabolic TIs had one focal hypermetabolic *** them,26(56.5%)were malignant and 20(43.5%)were ***_(max

关键词： Thyroid incidentaloma Malignancy Fluorodeoxyglucose positron emission tomography/computed tomography Standardized uptake value Cut-off

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Hepatocellular carcinoma in Budd-Chiari syndrome:A single center experience with long-term follow-up in South korea

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World Journal of Gastroenterology 2012年第16期18卷 1946-1952页

作者： Hana Park Jin young Yoon Kyeong Hye Park Do young Kim Sang hoon Ahn Kwang-Hyub Han Chae Yoon Chon Jun Yong Park Department of Internal Medicine Yonsei University College of MedicineSeoul 120-752South Korea Institute of Gastroenterology Yonsei University College of MedicineSeoul 120-752South Korea Liver Cirrhosis Clinical Research Center Seoul 120-752South Korea Brain South korea 21 Project for Medical Science Seoul 120-752South Korea

AIM:To evaluate long-term clinical course of BuddChiari syndrome(BCS) and predictive factors associated with the development of hepatocellular carcinoma(HCC) and ***:We analyzed 67 patients with BCS between June 1988 and May *** diagnosis of BCS was confirmed by hepatic venous outflow obstruction shown on abdominal ultrasound sonography,computed tomography,magnetic resonance imaging,or *** median follow-up period was 103 ± 156 [interquartile range(IQR)] ***:The median age of the patients was 47 ± 16(IQR) *** diagnosis,54 patients had cirrhosis,25(37.3%) Child-Pugh class A,23(34.3%) Child-Pugh class B,and six(9.0%) patients Child-Pugh class *** the follow-up period,HCC was developed in 17 patients,and the annual incidence of HCC in patients with BCS was 2.8%.Patients in HCC group(n = 17) had higher hepatic venous pressure gradient(HVPG) than those in non-HCC group(n = 50)(21 ± 12 mmHg vs 14 ± 7 mmHg,P = 0.019).The survival rate of BCS patients was 86.2% for 5 years,73.8% for 10 years,and 61.2% for 15 *** patients with BCS and HCC,survival was 79% for 5 years,43.1% for 10 years,and 21.5% for 15 ***:The incidence of HCC in patients with BCS was similar to that in patients with other etiologic cirrhosis in South *** HVPG is expected to provide additional information for predicting HCC development in BCS patients.

关键词： Budd-Chiari syndrome Hepatocellular carcinoma Prognosis

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Optic radiation injury in patients with aneurismal subarachnoid hemorrhage: a preliminary diffusion tensor imaging report

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Neural Regeneration Research 2018年第3期13卷 563-566页

作者： Sung Ho Jang Chul hoon Chang young Jin Jung Seong Ho Kim Jeong Pyo Seo Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Department of Neurosurgery College of Medicine Yeungnam University

Visual field defect is one of the various clinical manifestations in patients with subarachnoid hemorrhage（SAH）. Little is known about the pathogenic mechanism of visual field defect in SAH. In the current study,we investigated the diffusion tensor imaging （DTI） finding of the optic radiation in patients with SAH followingrupture of a cerebral artery aneurysm. We recruited 21 patients with aneurismal SAH （12 males, 9 females, mean age, 52.67 years; range, 41–68 years） who showed no definite lesion along the visual ***-one age-and sex-matched normal control subjects were also recruited. DTI data were acquired at an average of 5.9 weeks （range： 3–12 weeks） after onset and reconstruction of the optic radiation was performed using DTI-Studio software. The fractional anisotropy value, apparent diffusion coefficient value,and fiber number of the optic radiation were measured. The fractional anisotropy value of the optic radiation was significantly decreased, and the apparent diffusion coefficient value was significantly increased, in patients with aneurismal SAH than in normal control subjects. However, there was no significant difference in the fiber number of the optic radiation between patients with aneurismal SAH and normal control subjects. The decrement of fractional anisotropy value and increment of apparent diffusion coefficient value of the optic radiation in patients with aneurismal SAH suggest optic radiation injury. Therefore, we recommend a thorough evaluation for optic radiation injury in patient with aneurismal SAH.

关键词： nerve regeneration diffusion tensor imaging optic radiation subarachnoid hemorrhage visual field defect neural regeneration

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Dynamic Changes in Left and Right Cerebral Oxygen Saturation during Selective Cerebral Perfusion in young Infants

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Congenital Heart Disease 2023年第6期18卷 639-647页

作者： Hwa-young Jang Sang-Jun Beon Sung-hoon Kim In-Kyung Song Won-Jung Shin Department of Anesthesiology and Pain Medicine Laboratory for Cardiovascular DynamicsAsan Medical CenterUniversity of Ulsan College of MedicineSeoul05505Korea Department of Physician Education and Training Asan Medical CenterSeoul05505Korea

Objectives:We investigated whether the selective cerebral perfusion(SCP)technique causes differences in changes in cerebral perfusion between both hemispheres in young infants,using cerebral oxygen saturation(ScO2)as an ***,we determined the association between the discrepancy in ScO2 and cerebral perfu-sion pressure during ***:The difference in ScO2 between the left and right cerebral hemispheres(ΔScO2 Rt-Lt)was calculated during clamping of the innominate artery(IA)and during ***:In 25 infants(aged 2 to 78 days),the left and right ScO2 were well maintained(median 63.2%and 60.9%during IA clamping,respectively;64.0%and 65.6%during SCP,respectively).During IA clamping,right and left ScO2 decreased(med-ian-1.4%and-1.0%,respectively).During SCP,rightΔScO2 was higher compared to leftΔScO2(median 1.5%vs.0.6%;pyoung infants;this may depend on the perfusion pressure.

关键词： Cerebral circulation congenital heart defects monitoring near-infrared spectroscopy

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Paradoxical carbon dioxide embolism during laparoscopic hepatectomy without intracardiac shunt:A case report

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World Journal of Clinical Cases 2022年第9期10卷 2908-2915页

作者： Soeun Jeon Jeong-Min Hong Hyeon Jeong Lee Yesul Kim Hyunjong Kang Boo-young Hwang Dowon Lee young-hoon Jung Department of Anesthesia and Pain Medicine Pusan National UniversitySchool of MedicineBusan 49241South Korea Biomedical Research Institute Pusan National University HospitalBusan 49241South Korea

BACKGROUND Laparoscopic hepatectomy has recently become popular because it results in less bleeding than open ***,CO_(2)embolism occurs more *** CO_(2)embolisms during laparoscopic surgery are self-resolving and non-symptomatic;however,severe CO_(2)embolism may cause hypotension,cyanosis,arrhythmia,and cardiovascular *** particular,paradoxical CO_(2)embolisms are highly likely to cause neurological *** report a case of paradoxical CO_(2)embolism found on transesophageal echocardiography(TEE)during laparoscopic hepatectomy,although the patient had no intracardiac *** SUMMARY A 71-year-old man was admitted for laparoscopic left *** left hepatic vein ligation,the inferior vena cava was accidentally *** observed a sudden drop in oxygen saturation to 85%,decrease in systolic blood pressure(SBP)below 90 mm Hg,and reduction in end-tidal CO_(2)to 24 mm Hg.A“mill-wheel”murmur was auscultated over the *** fraction of inspired oxygen was increased to 100%with 5 cm H2O of positive end-expiratory pressure(PEEP)and hyperventilation was *** infusion was increased to maintain SBP above 90 mm Hg.A TEE probe was inserted,revealing gas bubbles in the right side of the heart,left atrium,left ventricle,and ascending *** surgeon reduced the pneumoperitoneum pressure from 17 to 14 mm Hg and repaired the damaged vessel ***,the patient’s hemodynamic status *** patient was transferred to the intensive care unit,recovering well without *** TEE monitoring is important to quickly determine the presence and extent of embolism in patients undergoing laparoscopic hepatectomy.

关键词： Carbon dioxide Embolism Laparoscopy Pneumoperitoneum Transesophageal echocardiography Case report

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Secondary endoscopic submucosal dissection for locally recurrent or incompletely resected gastric neoplasms

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World Journal of Gastroenterology 2018年第33期24卷 3776-3785页

作者： Da Hyun Jung young hoon Youn Jie-Hyun Kim Jae Jun Park Hyojin Park Department of Internal Medicine Gangnam Severance Hospital Yonsei University College of Medicine

AIM To investigate the feasibility and safety of secondary endoscopic submucosal dissection(ESD) for residual or locally recurrent gastric tumors. METHODS Between 2010 and 2017, 1623 consecutive patients underwent ESD for gastric neoplasms at a single tertiary referral center. Among these, 28 patients underwent secondary ESD for a residual or locally recurrent tumor. Our analysis compared clinicopathologic factors between primary ESD and secondary ESD groups. RESULTS The en bloc resection and curative rate of resection of secondary ESD were 92.9% and 89.3%, respectively. The average procedure time of secondary ESD was significantly longer than primary ESD(78.2 min vs 55.1 min, P = 0.004), and the adverse events rate was not significantly different but trended slightly higher in the secondary ESD group compared to the primary ESD group(10.7% vs 3.8%, P = 0.095). Patients who received secondary ESD had favorable outcomes without severe adverse events. During a mean follow-up period, no local recurrence occurred in patients who received secondary ESD. CONCLUSION Secondary ESD of residual or locally recurrent gastric tumors appears to be a feasible and curative treatment though it requires greater technical efficiency and longer procedure time.

关键词： Secondary endoscopic submucosal dissection Endoscopic submucosal dissection Gastric neoplasms Residual tumors Recurrent tumors

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Early rehabilitation programs after laparoscopic colorectal surgery:Evidence and criticism

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World Journal of Gastroenterology 2013年第46期19卷 8543-8551页

作者： Duck-Woo Kim Sung-Bum Kang Soo-young Lee Heung-Kwon Oh Myung-hoon In Department of Surgery Seoul National University Bundang Hospital

During the past several decades,early rehabilitation programs for the care of patients with colorectal surgery have gained *** randomized controlled trials and meta-analyses have confirmed that the implementation of these evidence-based detailed perioperative care protocols is useful for early recovery of patients after colorectal *** cared for based on these protocols had a rapid recovery of bowel movement,shortened length of hospital stay,and fewer complications compared with traditional care ***,most of the previous evidence was obtained from studies of early rehabilitation programs adapted to open colonic ***,limited evidence exists on the effects of early rehabilitation after laparoscopic rectal resection,although this procedure seems to be associated with a higher morbidity than that reported with traditional *** this article,we review previous studies and guidelines on early rehabilitation programs in patients undergoing rectal *** investigated the status of early rehabilitation programs in rectal surgery and analyzed the limitations of these *** also summarized indications and detailed protocol components of current early rehabilitation programs after rectal surgery,focusing on laparoscopic resection.

关键词： Colorectal cancer Enhanced recovery after surgery Early rehabilitation Fast-track Laparoscopy Rectal

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Practical operating flexibility of a bifunctional freestanding membrane for efficient anion exchange membrane water electrolysis across all current ranges

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Carbon Energy 2024年第9期6卷 306-324页

作者： Hong-Jin Son Jeemin Hwang Min young Choi Seung Hee Park Jae Hyuk Jang Byungchan Han Sung hoon Ahn Department of Bio-Chemical Engineering Chosun UniversityGwangjuRepublic of Korea Fuel Cell Research and Demonstration Center Hydrogen Energy Research DivisionKorea Institute of Energy Research(KIER)Buan-gunJeollabuk-doRepublic of Korea Department of Chemical and Biomolecular Engineering Yonsei UniversitySeoulRepublic of Korea Center for Research Equipment Korea Basic Science InstituteDaejeonRepublic of Korea

This study explores a symmetric configuration approach in anion exchange membrane(AEM)water electrolysis,focusing on overcoming adaptability challenges in dynamic ***,a rapid and mild synthesis technique for fabricating fibrous membrane-type catalyst electrodes is *** method leverages the contrasting oxidation states between the sulfur-doped NiFe(OH)_(2) shell and the metallic Ni core,as revealed by electron energy loss *** evaluations confirm that the S–NiFe(OH)_(2) active sites optimize free energy for alkaline water electrolysis *** technique bypasses traditional energy-intensive processes,achieving superior bifunctional activity beyond current *** symmetric AEM water electrolyzer demonstrates a current density of 2 A cm^(-2) at 1.78 V at 60℃ in 1 M koH electrolyte and also sustains ampere-scale water electrolysis below 2.0 V for 140 h even in ambient *** results highlight the system's operational flexibility and structural stability,marking a significant advance-ment in AEM water electrolysis technology.

关键词： AEM water electrolysis fibrous membrane iR correction free operational stability symmetric configuration

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Nanodendrites of platinum-group metals for electrocatalytic applications

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Nano Research 2018年第12期11卷 6111-6140页

作者： Nitin K.Chaudhari Jinwhan Joo Hyuk-bu Kwon Byeongyoon Kim Ho young Kim Sang hoon Joo Kwangyeol Lee Department of Chemistry Korea UniversitySeou102841Republic of Korea Research Institute of Natural Sciences (RINS) Korea UniversitySeou102841Republic of Korea School of Energy and Chemical Engineering Ulsan National Institute of Science and Technology (UNIST)Ulsan44919Republic of Korea

Developing highly efficient and durable catalysts for future electrochemical and energy applications is one of the main subjects of current studies in renewable energy generation. In the past several years, researchers have developed Pt-based alloy electrocatalyst nanomaterials that exhibit promising electrocatalytic properties for various electrochemical applications. The efficient structural and morphological control of Pt-based alloy materials plays a decisive role in achieving these enhanced electrocatalytic properties. The present review article emphasizes the recent progress and important developments in the synthesis and electrocatalytic applications of Pt-group-based nanodendrite materials. The following review will help the exploration and development of better catalysts for practical applications and aims to elucidate the nanodendrite structure of Pt-group metals.

关键词： nanodendrites platinum-group metals electrochemical and energy conversion nanostructure

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A Furan-Substituted Polymeric Hole-Transporting Material for Energy Level Regulation and Less Planarity in Colloidal Quantum Dot Solar Cells

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Energy & Environmental Materials 2023年第5期6卷 340-346页

作者： Jun woo Lee Duck hoon Lee younghoon Kim Jin young Park Hyung Ryul You Taiho Park Minjun Kim Jongmin Choi Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)77 Cheongam-RoNam-GuPohang Gyeongbuk 37673Korea Department of Chemical and Environmental Engineering Yale UniversityNew Haven CT 06511USA Department of Energy Science and Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Korea Department of Chemistry Kookmin UniversitySeoul 02707Korea RIKEN Center for Emergent Matter Science(CEMS) 2-1 HirosawaWako Saitama 351-0198Japan

For efficient colloidal quantum dot(CQD)solar cells(CQD-SCs),thiol-passivated p-type CQDs are generally used as a hole-transporting material(HTM);however,there are issues with the control of optoelectrical properties,low thiol passivation rate,and poor morphology with a power conversion efficiency(PCE)of approximately 11%.Although polymeric HTMs have been introduced to address these issues,maximizing efficiency and achieving green-solvent processability and thermal stability for commercialization is ***,we synthesize a novel benzodifuran(BDF)-based HTM(asy-ranPBTBDF)showing an electron-deficient state,low steric hindrance,and low planarity compared to those of a typical benzodithiophene(BDT)-based HTM(asy-ranPBTBDT).BDF properties lead to deep high occupied molecular orbital(HOMO)levels,closeπ-πstacking,excellent solubility,and amorphous properties related to efficiency,green-solvent processability,and thermal *** these benefits,the asy-ranPBTBDF-based CQD-SC showed enhanced open-circuit voltage(Voc)(0.65 V)and PCE(13.29%)compared to those of the asy-ranPBTBDT-based device(0.63 V and 12.22%)in toxic processes with *** asy-ranPBTBDF-based CQD-SC showed a PCE of 12.51%in a green-solvent process with 2-methylanisole and improved thermal stability at 80℃(83.8%retaining after 24 h)owing to less lateral crystallization than the asy-ranPBTBDT-based device(60.8%retaining after 24 h).

关键词： colloidal quantum dot green-solvent photovoltaics semiconducting polymers stability

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