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The clinical characteristics and risk factors for necrotizing soft tissue infection in children

儿科学研究(英文) 2024年第1期08卷 21-26页

作者： Liu Jing Chen Jigang Wang Yanni qi hongyan Yu Jing Department of Burn and Plastic Surgery Beijing Children’s Hospital Capital Medical University National Center for Children’s Health Beijing China

Importance: Necrotizing soft tissue infection (NSTI) is a serious infectious disease. However, the early clinical manifestations and indicators of NSTI in children are still ***: The purpose of this study was to analyze the clinical characteristics and risk factors of NSTI in pediatric ***: A total of 127 children with skin and soft tissue infection (SSTI) were treated at our hospital and divided into two groups: the NSTI group and the non-NSTI group, based on their discharge diagnosis from January 2011 to December 2022. Then, we collected and analyzed the clinical characteristics and risk factors of all patients, including sex and age, disease inducement, admission temperature, local skin manifestations, infection site, the presence of sepsis, bacterial culture, and laboratory ***: In our study, there was a statistical difference in the age distribution and disease inducement between NSTI and non-NSTI groups. The occurrence of local skin manifestations (blisters/bullae and ecchymosis) and the presence of sepsis significantly increased in the NSTI group compared to the non-NSTI group. Additionally, only the platelet count on laboratory tests was statistically different between the NSTI and non-NSTI groups. Finally, the logistic regression analysis suggested that local skin manifestations such as blisters/bullae, and ecchymosis, as well as the presence of sepsis, were identified as risk factors for ***: Children with SSTI and skin manifestations such as blisters/bullae, ecchymosis, and the presence of sepsis are at a higher risk of developing NSTI. These symptoms serve as useful indicators for early detection of NSTI.

关键词： Clinical characteristics Risk factors Necrotizing soft tissue infection Skin and soft tissue infection

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Early-life famine exposure,adulthood obesity patterns,and risk of low-energy fracture

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Frontiers of Medicine 2024年第1期18卷 192-203页

作者： hongyan qi Chunyan Hu Jie Zhang Lin Lin Shuangyuan Wang Hong Lin Xiaojing Jia Yuanyue Zhu Yi Zhang Xueyan Wu Mian Li Min Xu Yu Xu Tiange Wang Zhiyun Zhao Weiqing Wang Yufang Bi Meng Dai Yuhong Chen Jieli Lu Department of Endocrine and Metabolic Diseases Shanghai Institute of Endocrine and Metabolic DiseasesRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai200025China Shanghai National Clinical Research Center for Endocrine and Metabolic Diseases Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the People’s Republic of ChinaShanghai National Center for Translational MedicineRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai200025China

Malnutrition in early life increases the risk of osteoporosis,but the association of early-life undernutrition combined with adulthood obesity patterns with low-energy fracture remains *** study included 5323 community-dwelling subjects aged⩾40 years from ***-life famine exposure was identified based on the participants’birth *** obesity was assessed using the body mass index(BMI),and abdominal obesity was evaluated with the waist-to-hip ratio(WHR).Low-energy fracture was defined as fracture occurring after the age of⩾40 typically caused by falls from standing height or *** to the nonexposed group,the group with fetal,childhood,and adolescence famine exposure was associated with an increased risk of fracture in women with odds ratios(ORs)and 95%confidence intervals(CIs)of 3.55(1.57–8.05),3.90(1.57–9.71),and 3.53(1.05–11.88),respectively,but not in *** interactions were observed between fetal famine exposure and general obesity with fracture among women(P for interaction=0.0008).Furthermore,compared with the groups with normal BMI and WHR,the group of women who underwent fetal famine exposure and had both general and abdominal obesity had the highest risk of fracture(OR,95%CI:3.32,1.17–9.40).These results indicate that early-life famine exposure interacts with adulthood general obesity and significantly increases the risk of low-energy fracture later in life in women.

关键词： famine obesity body mass index waist-to-hip ratio low-energy fracture

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河岸植被类型对坡面流水动力特性影响研究

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水利技术监督 2024年第2期 197-200页

作者：齐鸿雁上饶市科信水土保持监测有限公司江西上饶334000

为研究河岸植被类型对坡面水土保持作用效果的影响,文章通过野外径流放水冲刷模拟试验方法,开展植被对坡面流水特性的耦合作用研究。结果表明:河岸带边坡流型为层流,雷诺数与放水流量及时间成正比,植被覆盖显著提高坡面径流雷诺数与弗... 详细信息

为研究河岸植被类型对坡面水土保持作用效果的影响,文章通过野外径流放水冲刷模拟试验方法,开展植被对坡面流水特性的耦合作用研究。结果表明:河岸带边坡流型为层流,雷诺数与放水流量及时间成正比,植被覆盖显著提高坡面径流雷诺数与弗雷德数,坡面植被可有效降低径流流速,具有良好的水土保持效果。研究结果可为水土保持治理提供参考。

关键词：植被类型坡面流水动力特性水土保持

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自体毛发移植治疗儿童瘢痕性秃发的临床疗效观察

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中华小儿外科杂志 2024年第2期45卷 143-147页

作者：冯瑞王燕妮齐鸿燕王继萍靳飞王伊宁国家儿童医学中心首都医科大学附属北京儿童医院烧伤整形外科北京100045

目的探究自体毛发移植技术在儿童瘢痕性秃发、秃眉中的疗效和经验。方法收集了北京儿童医院烧伤整形外科2019年1月至2021年2月收治的因手术、烧伤、外伤导致的瘢痕性秃发、秃眉患儿共13例,其中男10例,女3例;年龄为(7.0±3.0)岁,年龄范围... 详细信息

目的探究自体毛发移植技术在儿童瘢痕性秃发、秃眉中的疗效和经验。方法收集了北京儿童医院烧伤整形外科2019年1月至2021年2月收治的因手术、烧伤、外伤导致的瘢痕性秃发、秃眉患儿共13例,其中男10例,女3例;年龄为(7.0±3.0)岁,年龄范围是4~12岁;其中10例秃发,3例秃眉。根据患儿病情特点采取自体毛囊单位提取(follicular unit extraction,FUE)或毛囊单位头皮条切取(follicular unit transplantation,FUT)移植术,随访时计算成活率、毛发生长情况、并发症,并以问卷的形式按照非常满意、满意、不满意3个标准对患儿家属进行满意度评价。结果 13例中有8例采用FUE、4例采用FUT、1例采用FUT+FUE的治疗方式。术后随访6~12个月,13例患儿毛发成活率平均值为80.9%(植发77.8%,植眉91.5%),临床效果非常满意者4例,基本满意者7例,2例认为疗效不满意,且已实施完成二次加密术。所有患儿均无术后并发症,移植毛发接近自然毛发分布特点,且供区瘢痕不明显。结论自体毛发移植技术是治疗儿童瘢痕性秃发、秃眉的安全有效的手段,应当临床推广。

关键词：瘢痕秃发毛发移植术秃眉

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Transcriptome and metabolomics analysis revealed that CmWRKY49 regulating CmPSY1 promotes β-carotene accumulation in orange fleshed oriental melon

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Horticultural Plant Journal 2022年第5期8卷 650-666页

作者： Xiaoyu Duan Cai Jiang Yaping Zhao Ge Gao Meng Li hongyan qi Key Laboratory of Protected Horticulture of Education Ministry and Liaoning Province College of HorticultureShenyang Agricultural UniversityNational and Local Joint Engineering Research Centre of Northern HorticulturalFacilities Design and Application Technology(Liaoning)Shenyang 110866China Nanodigmbio Biotechnology Co. Ltd.Nanjing 210038China

The flesh color of oriental melons is an important commercial trait that affects consumer *** explore the mechanisms underlying the flesh color formation and regulation during fruit ripening,carotenoid-targeted metabolomic and RNA-seq analysis were conducted between white-fleshed(WF) and orange-fleshed(OF) oriental melon cultivars at different *** carotenoid-targeted metabolomic analysis indicated that β-carotene was the major metabolite that caused differences in flesh color between the two ***,through KEGG pathway enrichment and weighted gene co-expression network(WGCNA) analysis,metabolic pathways and related transcription factors that are associated with carotenoid metabolism were selected and transcriptome data was verified using ***,the yeast one hybrid and luciferase activity showed that the transcription factor CmWRKY49 could directly bind to the CmPSY1 promoter to activate its expression in the ’OF’ *** overexpression of CmWRKY49 in ’OF’ cultivar increased the β-carotene content,while the β-carotene content decreased when it was silenced in the same *** study provides insights into the underlying regulatory network of carotenoid metabolism in oriental melon fruit.

关键词： Oriental melon Carotenoid Transcriptome analysis WRKY CmPSY1

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打造江西科技金融品牌的若干思考与建议

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产业科技创新 2024年第2期6卷 35-38页

作者：齐洪彦张春艳刘晓霞江西省高新技术产业促进中心江西南昌330046 江西省科技事务中心江西南昌330046 江西师范大学科学技术学院江西南昌332020

金融是现代经济的血脉。近年来,国家越来越重视金融支持科技创新的作用。党的二十大报告强调,“营造有利于科技型中小微企业成长的良好环境,推动创新链产业链资金链人才链深度融合”。本文从区域科技金融发展的视角,着重梳理了江西科技... 详细信息

金融是现代经济的血脉。近年来,国家越来越重视金融支持科技创新的作用。党的二十大报告强调,“营造有利于科技型中小微企业成长的良好环境,推动创新链产业链资金链人才链深度融合”。本文从区域科技金融发展的视角,着重梳理了江西科技金融的发展现状,深入分析打造江西科技金融品牌的痛点与难点,并从强化组织领导、破除科技金融体制机制障碍、构建科技金融服务体系、加大科技金融投入以及发展科技金融人才等方面提出对策和建议,为科技强省提供理论支撑。

关键词：科技金融思考建议

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TGA转录因子在调控植物逆境应答和生长发育中的作用研究进展

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植物生理学报 2024年第7期60卷 1079-1086页

作者：徐东东东琳邵丽梁阿丹韩雨晴张玉洁刘涛齐红岩沈阳农业大学园艺学院设施园艺省部共建教育部重点实验室北方园艺设施设计与应用技术国家地方联合工程研究中心(辽宁)沈阳110866

TGA转录因子是一类广泛存在于植物中的重要转录因子家族,已被证明在调控植物逆境应答和生长发育中起着关键作用。本综述系统总结了TGA转录因子的分类和特征、在植物逆境应答及生长发育中的作用,并讨论和展望了TGA的未来研究方向,以期为... 详细信息

TGA转录因子是一类广泛存在于植物中的重要转录因子家族,已被证明在调控植物逆境应答和生长发育中起着关键作用。本综述系统总结了TGA转录因子的分类和特征、在植物逆境应答及生长发育中的作用,并讨论和展望了TGA的未来研究方向,以期为TGA转录因子功能的系统解析提供参考。

关键词： TGA转录因子生物胁迫非生物胁迫生长发育

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北京市密云区19家基层医院集中处方点评结果分析

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中国卫生标准管理 2024年第12期15卷 137-140页

作者：李荣宫淑艳王继宏齐红艳北京市密云区医院药剂科北京101500 北京市密云区妇幼保健院药剂科北京101500 北京市密云区鼓楼社区卫生服务中心药剂科北京101500

目的通过集中处方点评,了解北京市密云区基层医院用药现状,发现其不合理用药问题,通过反馈,规范临床医师处方行为,促进全区合理用药水平整体提高。方法对比密云区19家基层医院2016年、2019年和2022年3次集中处方点评结果,从处方合格率... 详细信息

目的通过集中处方点评,了解北京市密云区基层医院用药现状,发现其不合理用药问题,通过反馈,规范临床医师处方行为,促进全区合理用药水平整体提高。方法对比密云区19家基层医院2016年、2019年和2022年3次集中处方点评结果,从处方合格率、存在问题类型等进行分析。结果3次集中点评处方数分别是2284张、1938张和1900张,合格处方数分别是2058张、1702张和1801张,占比为90.11%、87.82%和94.79%。2022年集中点评处方合格率与2016年、2019年比较,差异有统计学意义(P<0.001)。处方中不合理问题类型主要是临床诊断书写不全、无中医证型诊断、适应证不适宜、用法、用量不适宜、联合用药不适宜及重复用药等。结论密云区基层医院处方合格率近几年稳步提升,但医师处方还存在一定程度的不合理用药现象。应进一步加强对临床医师、药师合理用药的培训,加强处方管理,促进临床安全、合理用药。

关键词：处方点评集中点评处方合格率不合理处方问题合理用药安全用药

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Mechanical Properties of Laser Welded Joint of Copper and Steel Dissimilar Metals

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Wuhan University Journal of Natural Sciences 2023年第1期28卷 68-76页

作者： REN Yiwen TAO Junhui LI Jie CHEN Xinqi ZHANG Lin WANG Chuanhui JIN Haiqin qi hongyan WANG Zhuo XIE Xing PAN Jie School of Physics and Mechanical&Electronical Engineering Hubei University of EducationWuhan 430205HubeiChina Institute for Functional Materials Hubei University of EducationWuhan 430205HubeiChina Hubei Engineering Research Center of Environmental Purification Materials Hubei University of EducationWuhan 430205HubeiChina Wuhan Second Ship Design Institute Wuhan 430070HubeiChina School of Materials Science and Engineering Huazhong University of Science and TechnologyWuhan 430074HubeiChina

In this research project,copper and stainless steel were connected by two laser welding methods:straight seam welding and swing ***,electronic tensile test machine,X-ray diffractometer,scanning electron microscope and metallographic microscope were used to analyze the tensile properties,macroscopic and microscopic structure morphology and phase of the welded *** on the experimental results,we determined that the strength of the straight seam welded joint was *** of the intermetallic compound near the weld in the swing welding process,it leads to stress concentration,crack cracking and strength *** addition,the oscillating laser beam also leads to the disorderly direction of columnar crystal and coarse structure,which makes the joint strength decrease.

关键词： copper steel dissimilar alloy laser welding mechanical properties

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Resistance and biosorption mechanism of silver ions by Bacillus cereus biomass

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Journal of Environmental Sciences 2011年第1期23卷 108-111页

作者： Li Li qing Hu Jinghai Zeng hongyan qi Guoqiang Zhuang Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China

Biosorption of silver ions onto Bacillus cereus biomass was investigated. Overall kinetic experiments were performed for the determination of the necessary contact time for the attainment of equilibrium. It was found that the overall biosorption process was best described by pseudo second-order kinetic model. The crystals detected by scanning electron microscope and X-ray photoelectron spectroscopy suggested the precipitation was a possible mechanism of biosorption. The molecular genetics of silver resistance of B. cereus biomass was also detected and illustrated by a whole cell sensor tool.

关键词： Bacillus cereus biosensor biosorption crystal isotherms kinetics silver

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