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Decellularized extracellular matrix scaffolds:Recent trends and emerging strategies in tissue engineering

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Bioactive Materials 2022年第4期7卷 15-31页

作者： Xuewei Zhang xi Chen Hua hong Rubei Hu Jiashang liu Changsheng liu Key Laboratory for Ultrafine Materials of Ministry of Education Frontiers Science Center for Materiobiology and Dynamic ChemistryEngineering Research Center for Biomaterials of Ministry of EducationSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai200237PR China

The application of scaffolding materials is believed to hold enormous potential for tissue *** the widespread application and rapid advance of several tissue-engineered scaffolds such as natural and synthetic polymer-based scaffolds,they have limited repair capacity due to the difficulties in overcoming the immunogenicity,simulating in-vivo microenvironment,and performing mechanical or biochemical properties similar to native organs/***,the emergence of decellularized extracellular matrix(dECM)scaffolds provides an attractive way to overcome these hurdles,which mimic an optimal non-immune environment with native three-dimensional structures and various bioactive *** consequent cell-seeded construct based on dECM scaffolds,especially stem cell-recellularized construct,is considered an ideal choice for regenerating functional organs/***,we review recent developments in dECM scaffolds and put forward perspectives accordingly,with particular focus on the concept and fabrication of decellularized scaffolds,as well as the application of decellularized scaffolds and their combinations with stem cells(recellularized scaffolds)in tissue engineering,including skin,bone,nerve,heart,along with lung,liver and kidney.

关键词： Decellularization ECM 3D scaffolds Tissue regeneration Recellularization

EXPERIMENTAL STUDY ON GAS-LIQUID TWO-PHASE FLOWS IN AN AREATION TANK BY USING IMAGE TREATMENT METHOD

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Journal of Hydrodynamics 2008年第5期20卷 650-655页

作者： CHENG Wen liu Wen-hong HU Bao-wei WAN Tian State Key Laboratory of Multiphase Flow in Power Engineering Xi＇an Jiaotong University Xi＇an 710049 China Environment Research Institute Xi＇an University of Technology Xi＇an 710048 China Environment Research Institute Xi＇an University of Technology Xi＇an 710048 China

Particle Image Velocimetry （PIV） technique was employed to study experimentally gas-liquid two-phase flow in an aeration tank. In terms of the PIV principles, an algorithm of PIV based on the Fast Fourier Transformation （FFT） was worked out. The PIV program was developed and verified, and then was used to measure three kinds of states in the testing device. The program was also used to calculate and analyze the related parameters. The experimental data indicate that the bubbles in testing device have the longest resident time and stronger turbulent intensity for the gas-liquid two-phase flow in a special case （Case 3）, resulting in great increase of the oxygen transferring speed and efficiency, whereby providing the basis for the selection design of aeration tank.

关键词： gas-liquid two-phase flow Particle Image Velocimetry (PIV) Fast Fourier Transformation (FFT) aeration tank

On the Station-Keeping and Control of the World Space Observatory/Ultraviolet

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Chinese Journal of Astronomy and Astrophysics 2006年第3期6卷 372-378页

作者： xi-Yun Hou Hai-hong Wang Lin liu Department of Astronomy Nanjing University Nanjing 210093 Institute of Space Enviromnent and Astronautics Nanjing University Nanjing 210093

Collinear libration points play an important role in deep space exploration because of their special positions and dynamical characteristics. Since motion around them is unstable, we need to control the spacecraft if we wish to keep them around such a libration point for a long time. Here we propose a continuous low-thrust control strategy, illustrated with numerical simulations combined with the orbit design and control of the World Space Observatory/UltraViolet （WSO/UV）.

关键词： celestial mechanics - WSO/UV - low thrust

Recent Progress on Flexible Room-Temperature Gas Sensors Based on Metal Oxide Semiconductor

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Nano-Micro Letters 2022年第12期14卷 310-351页

作者： Lang-xi Ou Meng-Yang liu Li-Yuan Zhu David Wei Zhang hong-Liang Lu State Key Laboratory of ASIC and System Shanghai Institute of Intelligent Electronics&SystemsSchool of MicroelectronicsFudan UniversityShanghai 200433People’s Republic of China Yiwu Research Institute of Fudan University Chengbei RoadYiwu City 322000ZhejiangPeople’s Republic of China

With the rapid development of the Internet of Things,there is a great demand for portable gas *** oxide semiconductors(MOS)are one of the most traditional and well-studied gas sensing materials and have been widely used to prepare various commercial gas ***,it is limited by high operating *** current research works are directed towards fabricating high-performance flexible room-temperature(FRT)gas sensors,which are effective in simplifying the structure of MOS-based sensors,reducing power consumption,and expanding the application of portable *** article presents the recent research progress of MOS-based FRT gas sensors in terms of sensing mechanism,performance,flexibility characteristics,and *** review comprehensively summarizes and discusses five types of MOS-based FRT gas sensors,including pristine MOS,noble metal nanoparticles modified MOS,organic polymers modified MOS,carbon-based materials(carbon nanotubes and graphene derivatives)modified MOS,and two-dimensional transition metal dichalcogenides materials modified *** effect of light-illuminated to improve gas sensing performance is further ***,the applications and future perspectives of FRT gas sensors are also discussed.

关键词： Metal oxide semiconductor Flexible gas sensor Room temperature Nanomaterials

Observations and Modeling of Incoming Longwave Radiation to Snow Beneath Forest Canopies in the West Tianshan Mountains, China

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Journal of Mountain Science 2014年第5期11卷 1138-1153页

作者： LU Heng WEI Wen-shou liu Ming-zhe HAN xi hong Wen xinjiang Institute of Ecology and Geography Chinese Academy of Sciences Graduate School of Chinese Academy of Sciences Institute of Desert Meteorology China Meteorological Administration Tianshan Station for Snow & Avalanche Research

Forest canopy reduces shortwave radiation and increases the incoming longwave radiation to snowpacks beneath forest canopies. Furthermore, the effect of forest canopy may be changed by complex topography. In this paper, we measured and simulated the incoming longwave radiation to snow beneath forest at different canopy openness in the west Tianshan Mountains, China(43°16'N, 84°24'E) during spring 2013. A sensitivity study was conducted to explore the way that terrain influenced the incoming longwave radiation to snow beneath forest canopies. In the simulation model, measurement datasets, including air temperature, incoming shortwave radiation above canopy, and longwave radiation enhanced by adjacent terrain, were applied to calculate the incoming longwave radiation to snow beneath forest canopy. The simulation results were consistent with the measurements on hourly scale and daily scale. The effect of longwave radiation enhanced by terrain was important than that of shortwave radiation above forest canopy with different openness except the 20% canopy openness. The longwave radiation enhanced due to adjacent terrain increases with the slope increase and temperature rise. When air temperature(or slope) is relatively low, thelongwave radiation enhanced by adjacent terrain is not sensitive to slope(or air temperature), but the sensitivity increases with the decrease of snow cover area on sunny slope. The effect of longwave radiation is especially sensitive when the snow cover on sunny slope melts completely. The effect of incoming shortwave radiation reflected by adjacent terrain on incoming longwave radiation to snow beneath forest canopies is more slight than that of the enhanced longwave radiation.

关键词： Incoming longwave radiation Snow beneath forest canopy Simulation model Complex topography Sensitivity study

Alkaloid from Dicranostigma leptopodum(Maxim) Fedde

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Chinese Chemical Letters 2009年第10期20卷 1218-1220页

作者： Yan Dang hong Fei Gong Jun xi liu Si Jiu Yu College of Veterinary Medicine Gansu Agricultural University Lanzhou 730070 China Key Laboratory for Natural Medicine of C-ansu Province Lanzhou Institute of Chemical Physics Chinese Academy of Sciences Lanzhou 730000 China

Phytochemical investigation of the whole plants of Dicranostigma leptopodum （Maxim） Fedde has lead to the isolation of five alkaloids： dicranostigmine （1）, isocorydinc （2）, corydine （3）, protopine （4） and sinoacutine （5）. Oxomorphine alkaloid （5） was isolated from the genus Dicranostigma for the first time and the new compound structure （1） was elucidated by various spectroscopic methods including 2D NMR techniques （gCOSY, HMQC, HMBC and NOESY） and HRESI-MS.

关键词： Papaveraceae Dicranostigma leptopodum Oxoaporphine Dicranostigmine

Heteropolytungstates Containing Organotin and Cobalt or Zinc Atom

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Chemical Research in Chinese Universities 1999年第4期15卷 317-321页

作者： WANG xiao-hong FANG xi-kui liu Jing-fu Department of Chemistry Northeast Normal UniversityChangchun 130024P.R.China

Organotin substituted heteropolytungstates with cobalt or zinc atom as the central atom, \{K 6H[XW 11 O 39 (RSn)]\}· n H 2O(X=Zn, Co; R=CH 3OOCCH 2CH 2, CH 2OOCCH(CH 3)CH 2, NCCH 2CH 2) were prepared and characterized by elemental analysis, IR, UV Vis spectroscopy, ESR, NMR spectroscopy and electrochemical study. The results show that these anions possess Keggin like structures.

关键词： Organotin Transition metal Heteropolyanion

Enhanced Anti-corrosion Ability and Biocompatibility of PLGA Coatings on MgZnYNd Alloy by BTSE-APTES Pre-treatment for Cardiovascular Stent

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Journal of Materials Science & Technology 2016年第9期32卷 845-857页

作者： Jing liu Tingfei xi Center for Biomedical Materials and Tissue Engineering Academy for Advanced Interdisciplinary Studies Peking University Shenzhen Institute Peking University

Bioabsorbable magnesium alloys are widely studied for various implant applications, as they reduce the risks such as severe inflammatory response existing in permanent metallic implants. However, the over-fast corrosion rate of magnesium alloy is usually an obstacle in biomedical applications. Here we report a simple two-step reaction to introduce anticorrosive silane pre-treatment on MgZnYNd alloys before coating with poly （glycolide-co-lactide）（PLGA）. The first step is to immerse the NaOH-activated MgZnYNd with bistriethoxysilylethane （BTSE） to form a cross-linked silane coating layer with enhanced corrosion resistance; the second step involves immobilizing amine functional groups for forming hydrogen bond with outer PLGA coating by treating the BTSE-modified MgZnYNd with 3-amino-propyltrimethoxysilane （APTES）. We characterized the BTSE-APTES pre-treated PLGA coating on MgZnYNd by scanning electron microscopy （SEM）, Fourier transform infrared spectroscopy （FF-IR）, X-ray photoelectron spectroscopy （XPS）, static contact angle and Acid Orange 7 measurement. Nano-scratch test was to verify that the scratch resistance of the PLGA coating with BTSE-APTES pre-treatment was superior to direct PLGA coating. Stan-dard electrochemical measurements along with the long-term immersion results indicated that the BTSE- APTES pre-treatment rendered better in vitro degradation behavior. Cell adhesion and cell viability tests with both vascular smooth muscle cells （VSMC） and human umbilical vein endothelial cells （EA. hy926） demonstrated that BTSE-APTES pre-treated MgZnYNd substrate had significantly more beneficial effects. The favorable anti-corrosion behavior and biocompatibility of BTSE-APTES pre-treated PLGA coatings on MgZnYNd alloy suggest that the novel two-step silanization procedure may have the great potential to enhance the performance of the magnesium-based biomaterials and provide a valid solution for the conversion modification of cardiovascular implants, taking the

关键词： Cardiovascular stent SilanizationAnti-corrosion Cytocompatibility MgZnYNd alloy

Broadband and perfect terahertz absorber based on multilayer metamaterial with cross-ring patterned structures

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Optoelectronics Letters 2025年第1期21卷 1-6页

作者： WEN Jin liu Zhanzhi WU Zhengwei PAN Yu ZHANG Ying School of Science Xi'an Shiyou University Shaanxi Key Laboratory of Measurement and Control Technology for Oil and Gas Wells

Broadband and perfect terahertz absorber based on multilayer metamaterial using cross-ring patterned structures is proposed and investigated. The structure of the absorber is double absorption layers consisting of a chromium cross ring and eight isosceles right triangles. The unique structure of the double absorbing layers excites the electric dipole multimode resonance, giving rise to high absorption performance. Meanwhile, the influence of construal parameters on absorber behavior is also discussed. The numerical results show that the absorption achieves over 90% ranging from 2.45 THz to 6.25 THz and 99% absorption in the range of 3.7—5.3 THz. The realization of broadband and perfect absorber is described using the impedance matching principle. It is obviously found that the absorber is insensitive to the high angle of incidence for both transverse electric(TE) and transverse magnetic(TM) polarizations. Compared with the former reports, this absorber has remarkable improved absorption efficiency and smaller period. The terahertz absorber may be found applications in the fields of energy capture and thermal detection.

关键词： Metamaterials