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Anti-Reflection Characteristics of Si Nanowires for Enhanced Photoluminescence from CdTe/CdS Quantum Dots

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Chinese Physics Letters 2018年第5期35卷 91-94页

作者： hong-Yu Wang dan shan Ling Xu Tongda College Nanjing University of Posts and TelecommunicationsNanjing 210003 National Laboratory of Solid State Microstructure and School of Electronic Science and Engineering Nanjing UniversityNanjing 210093 School of Electronic and Information Engineering Yangzhou Polytechnic InstituteYangzhou 225127

CdTe/CdS quantum dots（QDs） are fabricated on Si nanowires（NWs） substrates with and without Au nanoparticles（NPs）. The formation of Au NPs on Si NWs can be certified as shown in scanning electron microscopy images. The optical properties of samples are also investigated. It is interesting to find that the photoluminescence（PL） intensity of Cd Te/Cd S QD films on Si nanowire substrates with Au NPs is significantly increased,which can reach 8-fold higher than that of samples on planar Si without Au NPs. The results of finite-difference time-domain simulation indicate that Au NPs induce stronger localization of electric field and then boost the PL intensity of QDs nearby. Furthermore, the time-resolved luminescence decay curve shows the PL lifetime, which is about 5.5 ns at the emission peaks of QD films on planar, increasing from 1.8 ns of QD films on Si NWs to4.7 ns after introducing Au NPs into Si NWs.

关键词： Si QDs Anti-Reflection Characteristics of Si Nanowires for Enhanced Photoluminescence from CdTe/CdS Quantum Dots CdS

Environmental exposure during pregnancy and the risk of childhood allergic diseases

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World Journal of Pediatrics 2021年第5期17卷 467-475页

作者： Ming-Zhi Zhang shan-shan Chu Yan-Kai Xia dan-dan Wang Xu Wang State Key Laboratory of Reproductive Medicine.Center for Global Health School of Public Health.Nanjing Medical UniversityNanjing 211166.China Key Laboratory of Modern Toxicology of Ministry of Education School of Public Health.Nanjing Medical UniversityNanjing 211166.China Department of Endocrinology.Children's Hospital of Nanjing Medical University 72 Guangzhou Rd.Nanjing 210008China

Background Allergic diseases are one of the most common and important diseases that can exert hazardous effects on chil-dren's *** prevalence of allergic diseases in childhood is gradually increasing all over the world in recent *** causes of these diseases include anomalous immune responses and allergic inflammatory reactions,but the causes of allergic diseases in childhood are *** sources PubMed,Cochrane Library,Embase and Web of Science were searched for articles focusing on environmen-tal exposure during pregnancy and the risk of childhood allergic diseases,including asthma and atopic dermatitis,and the possible underlying *** In terms of environmental factors,allergice diseases in childhood are closely related to environmental chemical expo-sure during pregnancy,including bisphenols,phthalates acid esters,perfuorochemicals,polybrominated diphenyl ethers,and polychlorinated ***,allergic diseases in childhood are also closely associated with maternal dietary nutrition,maternal intake of drugs,such as acetylsalicylic acid(aspirin),paracetamol and antibiotics,and maternal *** Several harmful environmental factors during pregnancy can result in the interruption of the function of helper T cells(Th1/Th2),cytokines and immunoglobulins and may activate allergice reactions,which can lead to allergic diseases during childhood.

关键词： Allergic diseases Children Environment Pregnancy

Vertical distribution of sediment concentration

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第11期9卷 1560-1566页

作者： Sai-hua HUANG Zhi-lin SUN dan XU shan-shan XIA Department of Hydraulic and Ocean Engineering Zhejiang University Hangzhou 310058 China

A simple formula is proposed to predict the vertical distribution of a suspended load concentration in a 2D steady turbulent flow. The proposed formula significantly improves the well-known Rouse formula where sediment concentration has an infinitely large value at the channel bottom and a zero value at the water surface. Based on this formula and the logarithmic ve- locity profile, a theoretical elementary function for the transport rate of a suspended load is developed. This equation improves the Einstein equation in which the unit-width suspended sediment discharge must be solved by numerical integration and a contra- diction between the lower limit of the integral and that of velocity distribution exists.

关键词： Sediment concentration Vertical distribution Suspended load Sediment discharge

Bioelectrochemical response of a choline biosensor fabricated by using polyaniline

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Science China Chemistry 2009年第12期52卷 2275-2280页

作者： DING ShouNian shan dan SUN YueMing School of Chemistry and Chemical Engineering Southeast UniversityNanjing 211189China School of Chemistry&Chemical Engineering Yangzhou UniversityYangzhou 225002China

On the basis of the isoelectric point of an enzyme and the doping principle of conducting polymers, choline oxidase was doped in a polyaniline film to form a biosensor. The amperometric detection of choline is based on the oxidation of the H2O2 enzymatically produced on the choline biosensor. The response current of the biosensor as a function of temperature was determined from 3 to 40°C. An apparent activation energy of 22.8 kJ·mol?1 was obtained. The biosensor had a wide linear response range from 5 × 10?7 to 1 × 10?4 M choline with a correlation coefficient of 0.9999 and a detection limit of 0.2 μM, and had a high sensitivity of 61.9 mA·M?1·cm?2 at 0.50 V and at pH 8.0. The apparent Michaelis constant and the optimum pH for the immobilized enzyme are 1.4 mM choline and 8.4, respectively, which are very close to those of choline oxidase in solution. The effect of selected organic compounds on the response of the choline biosensor was studied.

关键词： choline choline oxidase biosensor polyaniline matrix

Portal hypertension exacerbates intrahepatic portosystemic venous shunt and further induces refractory hepatic encephalopathy: A case report

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World Journal of Clinical Cases 2021年第2期9卷 496-501页

作者： Ying-Hao Chang Xiao-Lei Zhou dan Jing Zhen Ni shan-hong Tang Department of Gastroenterology General Hospital of Western Theater CommandChengdu 610083Sichuan ProvinceChina Department of Infectious Diseases General Hospital of Western Theater CommandChengdu 610083Sichuan ProvinceChina

BACKGROUND Intrahepatic portosystemic venous shunt(IPSVS)is a rare hepatic disease with different clinical *** IPSVS patients with mild shunts are asymptomatic,while the patients with severe shunts present complications such as hepatic *** patients with portal hypertension accompanied by intrahepatic shunt,portal hypertension may lead to hemodynamic changes that may result in exacerbated portal shunt and increased shunt *** SUMMARY A 57-year-old man,with the medical history of chronic hepatitis B and liver cirrhosis,was admitted to our hospital with abnormal behavior for 10 *** had received the esophageal varices ligation and entecavir therapy 1 year *** with former examination results,the degree of esophageal varices was significantly reduced,while the right branch of the portal vein was significantly expanded and ***,abdominal ultrasound presented the right posterior branch of portal vein connected with the retrohepatic inferior vena *** imaging findings indicated the diagnosis of IPSVS and hepatic *** of radiologic interventions or surgical therapies,this patient had only accepted symptomatic *** recurrence of hepatic encephalopathy was observed during 1-year *** Hemodynamic changes may exacerbate intrahepatic portosystemic *** intervention or surgery should be carefully applied to patients with severe portal hypertension due to the risk of hemorrhage.

关键词： Intrahepatic portosystemic venous shunt Portal hypertension Hepatic encephalopathy Esophageal varices Symptomatic treatment Case report Hemodynamics

Analyses of Magnetic Force Images of Submicron Magnetic Mn-Ga Particles

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Chinese Physics Letters 1999年第5期16卷 333-335页

作者： LI dan HAN Bao-shan State key Laboratory of Magnetism Institute of PhysicsChinese Academy of SciencesBeijing 100080

The sample was prepared by implanting Mn^(+) ions at energy of 80keV and Mn^(+) ions of dose of 2×1017/cm^(2) directly into the semi-insulating(100)GaAs wafer,followed by rapid annealing at 830℃ for *** using magnetic force microscopy,both the topographic and magnetic force images of the submicron particles in the surface layer of the sample were *** formation of the magnetic particles is more complex,corresponding to more types of magnetic force image *** simulation was carried out by integrating the interactions between the tip and the particles,which can be used to judge the magnetization direction of particles more ***,the simulation has confirmed that all submicron magnetic particles are single crystals with a single *** fact,the simulated patterns of the single-domain particles are the“elemental”magnetic force patterns for magnetic materials,hence their acquirement and collection are the basis of the analysis and explanation of magnetic force images.

关键词： magnetic integrating hence

Effects of transferred NK4 gene on proliferation, migration, invasion and apoptosis of human prostate cancer DU145 cells

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Asian Journal of Andrology 2010年第3期12卷 381-389,I0010页

作者： dan Yue Yong Wang Ping Ma Yin-Yan Li hong Chen Ping Wang Chang-shan Ren Cancer Research Institute First Affiliated Hospital China Medical University Shenyang 110001 China Department of Urology Fourth Affiliated Hospital China Medical University Shenyang 110032 China Department of Ultrasound First Affihated Hospttal China Medical University Shenyang 110001 China

We investigated the ability of NK4, an antagonist of human hepatocyte growth factor （HGF）, to inhibit the influence of HGF on proliferation, migration, invasion and apoptosis of human prostate cancer cells. Expression vector pBudCE4.1-EGFP-NK4 containing NK4 cDNA was used to transfect human prostate cancer DU145 cells, and the effects of the autocrine NK4 on tumor cell proliferation, migration, invasion and apoptosis were assessed in vitro. in vivo, we subcutaneously implanted DU145 cells, mock-transfected clone （DU145/empty vector） cells and NK4- transfected clone （DU145/NK4） cells into nude mice, and then evaluated tumor growth, cell proliferation and cell apoptosis in vivo. We found that DU145/NK4 cells expressed NK4 protein. In the in vitro study, autocrine NK4 at- tenuated the HGF-induced tumor cell proliferation, migration and invasion, and stimulated apoptosis. Furthermore, autocrine NK4 effectively inhibited the HGF-induced phosphorylation of c-Met, extracellular signal-regulated kinase-1 （ERK1）. and protein kinase B 1/2 （Aktl/2）. Histological examination revealed that autocrine NK4 inhibited prolifera- tion and accelerated apoptosis of prostate cancer cells. These results show that genetic modification of DU145 cells with NK4 cDNA yields a significant effect on their proliferation, migration, invasion and apoptosis. Molecular targeting of HGF/c-Met by NK4 could be applied as a novel therapeutic approach to prostate cancer.

关键词： hepatocyte growth factor human prostate cancer NK4 DU 145 cells

Go-Ichi-Ni-San 2:A potential biomarker and therapeutic target in human cancers

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World Journal of Gastrointestinal Oncology 2022年第10期14卷 1892-1902页

作者： dan-dan shan Qiu-Xian Zheng Zhi Chen State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesNational Medical Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina

Cancer incidence and mortality are increasing globally,leading to its rising status as a leading cause of *** Go-Ichi-Ni-San(GINS)complex plays a crucial role in DNA replication and the cell *** GINS complex consists of four subunits encoded by the GINS1,GINS2,GINS3,and GINS4 *** findings have shown that GINS2 expression is upregulated in many diseases,particularly *** example,increased GINS2 expression has been found in cervical cancer,gastric adenocarcinoma,glioma,non-small cell lung cancer,and pancreatic *** correlates with the clinicopathological characteristics of the *** addition,high GINS2 expression plays a pro-carcinogenic role in tumor development by promoting tumor cell proliferation and migration,inhibiting tumor cell apoptosis,and blocking the cell *** review describes the upregulation of GINS2 expression in most human tumors and the pathway of GINS2 in tumor ***2 may serve as a new marker for tumor diagnosis and a new biological target for therapy.

关键词： Go-Ichi-Ni-San Go-Ichi-Ni-San 2 Cancer Biomarker Clinicopathological characteristics Molecular mechanism

Polymerization-Amplified Photoacoustic Signal by Enhancing Near-Infrared Light-Harvesting Capacity and Thermal-to-Acoustic Conversion

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Chinese Journal of Polymer Science 2022年第9期40卷 1090-1100页

作者： He-Qi Gao Jing-Tian Zhang Xin-Wen Qi Di Jiao Yu-Ning hong Ke shan Xiang-Long Kong dan Ding Key Laboratory of Bioactive Materials Ministry of Educationand College of Life SciencesNankai UniversityTianjin 300071China Center for AIE Research Shenzhen Key Laboratory of Polymer Science and TechnologyGuangdong Research Center for Interfacial Engineering of Functional MaterialsCollege of Materials Science and EngineeringCollege of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China Department of Chemistry and Physics La Trobe Institute for Molecular ScienceLa Trobe UniversityMelbourneVictoria3086Australia shandong Artificial intelligence Institute and shandong Computer Science Center Qilu University of TechnologyJinan 250353China

As a frontier imaging technique for biomedical applications,photoacoustic(PA)imaging has been developed *** development of new design strategies and excellent PA imaging reagents to boost PA conversion is eagerly desirable for high quality PA imaging but complicated to ***,we develop a new strategy in which PA imaging reagents with better properties can be easily optimized by polymerization.A series of new PA imaging reagents were designed and *** polymerization strategy can effectively promote the PA signal by specifically increasing the thermal-to-acoustic conversion *** these materials shared the same building units,the optimized effectiveness of polymerization strategy in terms of near-infrared light-harvesting capacity and thermal-to-acoustic conversion efficiency are discussed,*** polymers with intense intramolecular motion exhibit an amplified PA signal by elevating thermal-to-acoustic conversion and its higher light-harvesting capability at redshifted *** simultaneously strong PA signal and photothermal conversion efficiency of p-TTmB NPs enable precise PA imaging and effective photothermal *** work highlights a simple and available design guideline of polymerization for amplifying the PA effect and optimizing existing materials.

关键词： Intramolecular motion Thermal-to-acoustic conversion Photoacoustic imaging Photothermal conversion efficiency Polymerization