Polymerization-Amplified Photoacoustic Signal by Enhancing Near-Infrared Light-Harvesting Capacity and Thermal-to-Acoustic Conversion

作     者：He-Qi Gao Jing-Tian Zhang Xin-Wen Qi Di Jiao Yu-Ning Hong Ke Shan Xiang-Long Kong Dan Ding He-Qi Gao;Jing-Tian Zhang;Xin-Wen Qi;Di Jiao;Yu-Ning Hong;Ke Shan;Xiang-Long Kong;Dan Ding

作者机构：Key Laboratory of Bioactive MaterialsMinistry of Educationand College of Life SciencesNankai UniversityTianjin 300071China Center for AIE ResearchShenzhen Key Laboratory of Polymer Science and TechnologyGuangdong Research Center for Interfacial Engineering of Functional MaterialsCollege of Materials Science and EngineeringCollege of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China Department of Chemistry and PhysicsLa Trobe Institute for Molecular ScienceLa Trobe UniversityMelbourneVictoria3086Australia Shandong Artificial intelligence Institute and Shandong Computer Science CenterQilu University of TechnologyJinan 250353China 

出 版 物：《Chinese Journal of Polymer Science》 (高分子科学（英文版）)

年 卷 期：2022年第40卷第9期

页      面：1090-1100页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 0836[工学-生物工程] 

基　　金：supported by the National Key R&D Program of China (Intergovernmental Cooperation Project, 2017YFE0132200) the National Natural Science of Fundation of China (Nos.51961160730, 51873092, and 81921004) the Fundamental Research Funds for the Central Universities the Tianjin Science Fund for Distinguished Young Scholars (19JCJQJC61200) 

主　　题：Intramolecular motion Thermal-to-acoustic conversion Photoacoustic imaging Photothermal conversion efficiency Polymerization 

摘      要：As a frontier imaging technique for biomedical applications,photoacoustic(PA)imaging has been developed *** development of new design strategies and excellent PA imaging reagents to boost PA conversion is eagerly desirable for high quality PA imaging but complicated to ***,we develop a new strategy in which PA imaging reagents with better properties can be easily optimized by polymerization.A series of new PA imaging reagents were designed and *** polymerization strategy can effectively promote the PA signal by specifically increasing the thermal-to-acoustic conversion *** these materials shared the same building units,the optimized effectiveness of polymerization strategy in terms of near-infrared light-harvesting capacity and thermal-to-acoustic conversion efficiency are discussed,*** polymers with intense intramolecular motion exhibit an amplified PA signal by elevating thermal-to-acoustic conversion and its higher light-harvesting capability at redshifted *** simultaneously strong PA signal and photothermal conversion efficiency of p-TTmB NPs enable precise PA imaging and effective photothermal *** work highlights a simple and available design guideline of polymerization for amplifying the PA effect and optimizing existing materials.