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Journal of Semiconductors 2023年第9期44卷 1-2页

作者： hoi-sing.kwok Zhiyong Fan Department of Electronic and Computer Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong Kong SARChina State Key Laboratory of Advanced Displays and Optoelectronics Technologies HKUSTClear Water BayKowloonHong Kong SARChina

This year marks the tenth anniversary of the State Key Laboratory of Advanced Displays and Optoelectronics Technologies(SKLADOT)at the Hong Kong University of Science and Technology(HKUST).The predecessor of SKLADOT w... 详细信息

关键词： ADO Key UST

Exercise preconditioning alleviates ischemia-induced memory deficits by increasing circulating adiponectin

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Neural Regeneration Research 2025年第5期20卷 1445-1454页

作者： Meifeng Zheng Borui Zhang Sonata S Y Yau kwok-Fai So Li Zhang Haining Ou Department of Rehabilitation Medicine Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Department of Rehabilitation Medicine The Fifth Clinical College of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Key Laboratory of CNS Regeneration(Ministry of Education) Guangdong-Hong Kong-Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina Department of Rehabilitation Sciences The Hong Kong Polytechnic UniversityHong Kong Special Administrative RegionChina State Key Laboratory of Brain and Cognitive Science Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina Center for Exercise and Brain Science School of PsychologyShanghai University of SportShanghaiChina Neuroscience and Neurorehabilitation Institute University of Health and Rehabilitation SciencesQingdaoShandong ProvinceChina

Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug *** exercise enhances neurogenesis and synaptogenesis,and has been widely used for functional rehabilitation after *** this study,we determined whether exercise training before disease onset can alleviate the severity of cerebral *** also examined the role of exercise-induced circulating factors in these *** mice were subjected to 14 days of treadmill exercise training before surgery for middle cerebral artery *** found that this exercise pre-conditioning strategy effectively attenuated brain infarct area,inhibited gliogenesis,protected synaptic proteins,and improved novel object and spatial memory *** analysis showed that circulating adiponectin plays a critical role in these preventive effects of *** activation of adiponectin receptors by Adipo Ron mimicked the effects of exercise,while inhibiting receptor activation abolished the exercise *** summary,our results suggest a crucial role of circulating adiponectin in the effects of exercise pre-conditioning in protecting against cerebral ischemia and supporting the health benefits of exercise.

关键词： adiponectin cerebral ischemia exercise pre-conditioning hippocampus memory function middle cerebral artery occlusion prefrontal cortex synaptic proteins treadmill exercise

H-plasma-assisted aluminum induced crystallization of amorphous silicon

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Journal of Semiconductors 2012年第6期33卷 125-128页

作者：李娟刘宁罗翀孟志国熊绍珍 hoi sing.kwok Institute of Photo-Electronics Nankai UniversityTianjin Key Laboratory for Photo-Electronic Thin Film Devices and Technology Department of Electronic and Computer Engineering The Hong Kong University of Science and Technology

A technique to improve and accelerate aluminum induced crystallization（AIC） by using hydrogen plasma is *** spectroscopy and secondary ion mass spectrometry of crystallized poly-Si thin films show that hydrogen plasma radicals reduce the crystallization time of *** technique shortens the annealing time from 10 to 4 h and increases the Hall mobility from 22.1 to 42.5 cm^2/（V·s）.The possible mechanism of AIC assisted by hydrogen radicals is also discussed.

关键词： poly-silicon H-plasma aluminum induced crystallization

Kerr effect and Kerr constant enhancement in vertically aligned deformed helix ferroelectric liquid crystals

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Chinese Physics B 2016年第9期25卷 9-12页

作者： Liangyu Shi Abhishek Kumar Srivastava Vladimir G Chigrinov hoi-sing.kwok State Key Laboratory on Advanced Displays and Optoelectronics Technologies Hong Kong University of Science and Technology

In this article,we review recently achieved Kerr effect progress in novel liquid crystal（LC） material：vertically aligned deformed helix ferroelectric liquid crystal（VADHFLC）.With an increasing applied electric field,the induced inplane birefringence of LCs shows quadratic *** theoretical calculations and experimental details are *** an enhanced Kerr constant to 130 nm/V2,this VADHFLC cell can achieve a 2π modulation by a small efficient electric field with a fast response around 100 μs and thus can be employed in both display and photonics devices.

关键词： Kerr effect deformed helix ferroelectric liquid crystal phase modulation of light

Letter from the Editor-in-Chief

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Neural Regeneration Research 2025年第1期20卷 5-5页

作者： kwok-Fai So Neural Regeneration Research

Greetings esteemed readers,As we embark on a new year filled with promise and innovation,it is my pleasure to reflect on the remarkable achievements and advancements in the journal Neural Regeneration Research(NRR)showcased throughout ***,the 2024 International Neural Regeneration Symposium(INRS2024)and the 15^(th) Asia Pacific Symposium on Neural Regeneration(APSNR),held from April 12^(th) to 14^(th) in Guangzhou,China,stand as shining examples of collaboration,knowledge exchange,and scientific excellence.

关键词： Regeneration filled journal

Commentary on:“Human neural stem cell-derived artificial organelles to improve oxidative phosphorylation”

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Neural Regeneration Research 2025年第10期20卷 3040-3040页

作者： kwok-Fai So Key Laboratory of CNS Regeneration(Ministry of Education) Guangdong-Hong Kong-Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina State Key Laboratory of Brain and Cognitive Science Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina Neuroscience and Neurorehabilitation Institute University of Health and Rehabilitation SciencesQingdaoShandong ProvinceChina

Mitochondrial function is fundamental to neuroregeneration,particularly in neurons,where high energy demands are essential for repair and recovery(Patrón and Zinsmaier,2016;Beckervordersandforth et al.,2017;Iwata et al.,2023).Mitochondrial dysfunction,characterized by an imbalance in ATP levels and excessive production of mitochondrial reactive oxygen species,is a key factor that impedes neural regeneration in neurodegenerative diseases and after neuronal injury(Han et al.,2016,2020;Zheng et al.,2016;Zong et al.,2024).

关键词： neural Becker Human

Advances in mobility enhancement of ITZO thin-film transistors:a review

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Journal of Semiconductors 2023年第9期44卷 11-25页

作者： Feilian Chen Meng Zhang Yunhao Wan Xindi Xu Man Wong hoi-sing.kwok College of Electronic and Information Engineering Shenzhen UniversityShenzhen 518060China Institute of Microscale Optoelectronics(IMO) Shenzhen UniversityShenzhen 518060China State Key Laboratory of Advanced Displays and Optoelectronics Technologies The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina

Indium-tin-zinc oxide(ITZO)thin-film transistor(TFT)technology holds promise for achieving high mobility and offers significant opportunities for *** paper provides a review of progress made in improving the mobility of ITZO *** paper begins by describing the development and current status of metal-oxide TFTs,and then goes on to explain the advantages of selecting ITZO as the TFT channel *** evaluation criteria for TFTs are subsequently introduced,and the reasons and significance of enhancing mobility are *** paper then explores the development of high-mobility ITZO TFTs from five perspectives:active layer optimization,gate dielectric optimization,electrode optimization,interface optimization,and device structure ***,a summary and outlook of the research field are presented.

关键词： thin-film transistor(TFT) indium-tin-zinc oxide(ITZO)TFT mobility active matrix(AM)displays

Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

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Neural Regeneration Research 2025年第10期20卷 2923-2937页

作者： Yan Li Peng Hao Hongmei Duan Fei Hao Wen Zhao Yudan Gao Zhaoyang Yang kwok-Fai So Xiaoguang Li Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina China Rehabilitation Science Institute China Rehabilitation Research CenterBeijing Key Laboratory of Neural Injury and RehabilitationBeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory for Biomaterials and Neural Regeneration School of Engineering MedicineBeihang UniversityBeijingChina Guangdong-HongKong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan UniversityGuangzhouGuangdong ProvinceChina Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) GuangzhouGuangdong ProvinceChina Department of Ophthalmology and State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administration RegionChina Center for Brain Science and Brain-Inspired Intelligence Guangdong-HongKong-Macao Greater Bay AreaGuangzhouGuangdong ProvinceChina Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Biomedical Engineering School of Biological Science and Medical EngineeringBeihang UniversityBeijingChina

The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after ***,whether it is possible to stimulate neurogenesis and reconstruct cortical layers II to VI in non-neurogenic regions,such as the cortex,remains *** this study,we implanted a hyaluronic acid collagen gel loaded with basic fibroblast growth factor into the motor cortex immediately following traumatic *** findings reveal that this gel effectively stimulated the proliferation and migration of endogenous neural stem/progenitor cells,as well as their differentiation into mature and functionally integrated ***,these new neurons reconstructed the architecture of cortical layers II to VI,integrated into the existing neural circuitry,and ultimately led to improved brain *** findings offer novel insight into potential clinical treatments for traumatic cerebral cortex injuries.

关键词： adult endogenous neurogenesis basic fibroblast growth factor-hyaluronic acid collagen gel cortical remodeling functional recovery migration motor cortex injury neural circuits neural stem cells newborn neurons proliferation

Synthesis and properties of poly(1-phenyl-1-octyne)s containing stereogenic and chromophoric pendant groups

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Science China Chemistry 2009年第10期52卷 1691-1702页

作者： LAM Jacky W.Y. JIM Cathy K.W. kwok hoi sing Department of Chemistry The Hong Kong University of Science & Technology Center for Display Research The Hong Kong University of Science & Technology

Poly(1-phenyl-1-octyne)s containing different stereogenic and chromophoric pendants {-[(C6H13)C= C(C6H4-p-CO2-R)] n -R = [(1S)-endo]-(?)-borneyl (P3), (1R,2S,5R)-(?)-menthyl (P4), -C6H4-p-(1R,2S,5R)-(?)-menthyl (P5), 2-napthyl (P6), 4-biphenylyl (P7)} have been designed and synthesized. The polymers are prepared in moderate yields by WCl6-Ph4Sn and possess high molecular weights (M w up to 64000). The structures and properties of the polymers are characterized and evaluated by NMR, TGA, UV, CD, PL, and EL analyses. All the polymers are thermally stable and their temperatures for 5% weight loss locate in the range of 300 to 416°C under nitrogen. The energy band gaps of all the polymers are ～3.0 eV. Polymers P4 and P5 show CD absorptions associated with the helicity of the polymer segments. Excitation of the THF solutions of P3–P7 by UV irradiation gives strong blue lights of ～485 nm with quantum yields higher than 20%. The thin films of the polymers also emit in the same spectral region, indicative of little aggregation-caused quenching of light emission. Multilayer EL devices with a configuration of ITO/Polymer:PVK/BCP/Alq3/LiF/Al are constructed, which emit blue lights of ～487 nm. The maximum luminance and external quantum efficiency vary with the pendant groups, with P6 exhibiting the highest external quantum efficiency of 0.16%. The spectra stability of the EL devices is outstanding and the EL peak maximum experiences little change with the applied voltage.

关键词： chiral photoluminescence polyacetylene electroluminescence helicity

Crystallization of amorphous silicon beyond the crystallized polycrystalline silicon region induced by metal nickel

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Chinese Physics B 2017年第1期26卷 353-356页

作者： Dongli Zhang Mingxiang Wang Man Wong hoi-sing.kwok Department of Microelectronics Soochow University Suzhou 215006 China Center for Display Research Department of Electronic and Computer Engineering the Hong Kong University of Science and Technology Kowloon Hong Kong China

Crystallization of amorphous silicon（a-Si） which starts from the middle of the a-Si region separating two adjacent metal-induced crystallization（MIC） polycrystalline silicon（poly-Si） regions is observed. The crystallization is found to be related to the distance between the neighboring nickel-introducing MIC windows. Trace nickel that diffuses from the MIC window into the a-Si matrix during the MIC heat-treatment is experimentally discovered, which is responsible for the crystallization of the a-Si beyond the MIC front. A minimum diffusion coefficient of 1.84×10^-9cm^2/s at 550℃ is estimated for the trace nickel diffusion in a-Si.

关键词： metal-induced crystallization poly-Si nickel diffusion coefficient