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Comparison of Inspection Data by Difference in Odour Inspection Kit (Including Results of Young and Old Age)

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Journal of Health Science 2019年第3期7卷 160-165页

作者： Naomi Katayama Shoko Kondo Yui Nakayama Takafumi Nakada Seiya Goto Satofumi Sugimoto WakakoKinoshita Masaaki Teranisi Michihiko Sone Yasushi Fujimoto Hironao Otake hirokazu suzuki NaokiSaji Seiichi Nakata Tsutomu Nakashima Nagoya Women's University Nagoya City 467-8610Japan Graduate School of Nagoya Women’s University Nagoya City 467-8610Japan Department of Otorhinolaryngology Nagoya University Graduate School of MedicineNagoya City 466-8550Japan Watanabe Hospital Mihama TownChita-gun 470-3235Japan National Center for Geriatrics and Gerontology Obu City 474-8511Japan Otake Otolaryngology Hospital Kariya CityAichi 448-0857Japan Department of Otolaryngology Second Hospital Fujita Health University School of MedicineNagoya City 545-8509Japan Ichinomiya Medical Treatment & Habitaiton Center Ichinomiya City 494-0081Japan

The present study examined the relationship between olfactory function for ten years. A personal function test was calculated from the Nagoya Women’s University study database, and the odor stick identification test and open essence identification test were administered to healthy young and elderly people. The participants were community dwellers who voluntarily participated in the Nagoya Women’s University Study and had managed everyday life by themselves. We combined data of 2018 and checked two kinds of the olfactometry result. These data were made from a consultation result list which was handed to a testee by hand. The test age was in his/her 80s from 40s and in his/her 20s from 10s. The data were compared according to the generation (young age is 20.1 ± 0.7 years old and old age is 74.5 ± 10.0 years old). We conducted two kinds of olfaction tests. The Odour Stick Identification Test (OSIT-J) was used to assess odour perception. This test possesses high reliability and validity. The OSIT-J includes 12 different odorants to be identified. The Odour Essence Identification Test was used to assess odour perception, too. It also includes 12 different odorants to be identified. We compared the answer of generation and compared the results of the two olfactory tests. As a result, there were no statistically significant differences in the total number of correct answers in young people and old people in the two olfactory test results. In addition, we compare young people and old people who increased the number of correct answer in the two kinds of olfactory examination, the same person, and those who decreased, but there was no statistically significant difference. However, there were statistically significant differences between India ink and perfume and Household (domestic) gas compared with young people and old people with two kinds of olfactory test results. From the results of this study, it was found that the results of two kinds of olfactory test can be used tog

关键词： Healthy elderly people healthy young people olfactory function the odor stick test the open essence test

Comparison of Survey Results on Subjective Dizziness,Hearing and Tinnitus and Stabilometry Test Results in Yakumo Inhabitant Examination Study (Comparison of 2005, 2007 and 2015, 2017)

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Journal of Health Science 2019年第3期7卷 151-159页

作者： Naomi Katayama Shoko Kondo Yui Nakayama Takafumi Nakada Naoki Saji Seiya Goto Satofumi Sugimoto Wakako kinoshita Masaaki Teranisi Michihiko Sone Yasushi Fujimoto Hironao Otake hirokazu suzuki Seiichi Nakata Tsutomu Nakashima Yukiharu Hasegawa Nagoya Women’s University Nagoya City 467-8610Japan Graduate School of Nagoya Women’s University Nagoya City 467-8610Japan Department of Otorhinolaryngology Nagoya University Graduate School of MedicineNagoya City 466-8550Japan Watanabe Hospital Mihama TownChita-gun 470-3235Japan National Center for Geriatrics and Gerontology Obu City 474-851Japan Otake Otolaryngology Hospital Kariya City 448-0857Japan Department of Otolaryngology Second Hospital Fujita Health University School of MedicineNagya City 545-8509Japan Ichinomiya Medical Treatment &Habitaiton Center Ichinomiya City 494-0018Japan Department of Occupational Therapy Kansai University of Welfare SciencesOsaka fu 582-0026Japan

Abstract: The Nagoya University Hospital otolaryngology department is doing the prospective cohort study in Yakumo-cho, Hokkaido, Japan from 2005, because this place is a little transfer of the population. Most of inhabitants of Yakumo-cho engage in fishery and agriculture as work mainly. We perform questionary survey using an interview vote. The item is “having feeling of dizziness or not”,“quality of hearing” and “having tinnitus or not”. Furthermore, we go for the examination of stabilometry, too. We compared 2015, 2017 with 2005, 2007 among Yakumo-cho inhabitant examination data this time. As a result, participant with a feeling of conscious dizziness got a bad reputation of the hearing consciously. In addition, participant with a feeling of conscious dizziness had tinnitus consciously. Furthermore, the participant with a feeling of conscious dizziness had bad stabilometry result. As a result of having compared ten years later, we understood that stabilometry result worsened if 60s became in 70s with or without a feeling of dizziness consciously. When there is a feeling of conscious dizziness, it is necessary to perform an examination of stabilometry as routine work. In addition, it is necessary to inspect stabilometry if participants have the bad hearing or tinnitus with a feeling of dizziness in particularly.

关键词： Feeling of dizziness hearing tinnitus stabilometry Yakumo study

Dehiscence following successful endoscopic closure of gastric perforation during endoscopic submucosal dissection

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World Journal of Gastroenterology 2012年第31期18卷 4224-4227页

作者： Masau Sekiguchi Haruhisa suzuki Ichiro Oda Shigetaka Yoshinaga Satoru Nonaka Makoto Saka Hitoshi Katai hirokazu Taniguchi Ryoji Kushima Yutaka Saito Endoscopy Division National Cancer Center HospitalTokyo 104-0045Japan Gastric Surgery Division National Cancer Center HospitalTokyo 104-0045Japan Pathology Division National Cancer Center HospitalTokyo 104-0045Japan

Gastric perforation is one of the most serious complications that can occur during endoscopic submucosal dissection(ESD).In terms of the treatment of such perforations,we previously reported that perforations immediately observed and successfully closed with endoclips during endoscopic resection could be managed *** now report the first case in our medical facility of a gastric perforation during ESD that was ineffectively treated conservatively even after successful endoscopic *** December 2006,we performed ESD on a recurrent early gastric cancer in an 81-year-old man with a medical history of laparotomy for cholelithiasis.A perforation occurred during ESD that was immediately observed and successfully closed with endoclips so that ESD could be continued resulting in an en-bloc *** conservative management was conducted following ESD,however,an endoscopic examination five days after ESD revealed dehiscence of the perforation requiring an emergency laparotomy.

关键词：胃穿孔层剥离内镜关闭膜下保守治疗 ESD 医疗机构

The increase in surface CXCR4 expression on lung extravascular neutrophils and its effects on neutrophils during endotoxin-induced lung injury

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Cellular & Molecular Immunology 2011年第4期8卷 305-314页

作者： Mitsuhiro Yamada Hiroshi Kubo Seiichi Kobayashi Kota Ishizawa Mei He Takaya suzuki Naoya Fujino Hiroyuki Kunishima Masamitsu Hatta Katsushi Nishimaki Tetsuji Aoyagi Kouichi Tokuda Miho Kitagawa Hisakazu Yano hirokazu Tamamura Nobutaka Fujii Mitsuo Kaku Department of Regional Cooperation for Infectious Diseases Tohoku University Graduate School of MedicineSendaiMiyagiJapan Department of Advanced Preventive Medicine for Infectious Disease Tohoku University Graduate School of MedicineSendaiMiyagiJapan Department of Respiratory Medicine Japanese Red-Cross Ishinomaki HospitalIshinomakiMiyagiJapan Department of Infection Control and Laboratory Diagnostics Tohoku University Graduate School of MedicineSendaiMiyagiJapan Department of Clinical Microbiology with Epidemiological Research&Management and Analysis of Infectious Diseases Tohoku University Graduate School of MedicineSendaiMiyagiJapan Institute of Biomaterials and Bioengineering Tokyo Medical and Dental UniversityChiyoda-kuTokyoJapan Graduate School of Pharmaceutical Sciences Kyoto UniversityKyotoJapan

Inflammatory stimuli,such as a microbes or lipopolysaccharides,induce a rapid release of neutrophils from the bone marrow and promote neutrophil migration into inflamed sites to promote host ***,an excess accumulation and retention of neutrophils in inflamed tissue can cause severe tissue injuries in the later stages of *** studies have reported that both CXCL12 levels in injured lungs and its receptor,CXCR4,on accumulated neutrophils in injured lungs,increased;furthermore,these studies showed that the CXCL12/CXCR4 signaling pathway participated in neutrophil accumulation in the later stages of lipopolysaccharide(LPS)-induced lung ***,the mechanisms underlying this increase in surface CXCR4 expression in neutrophils remain *** this study,we found that surface CXCR4 expression increased in extravascular,but not intravascular,neutrophils in the lungs of LPS-induced lung injury model ***,ex vivo studies revealed that CXCL12 acted not only as a chemoattractant,but also as a suppressor of cell death for the lung neutrophils expressing ***,one of the native ligands for L-selectin,induced the increase of surface CXCR4 expression on isolated circulating neutrophils,suggesting that the activation of L-selectin may be involved in the increase in surface *** findings show that surface CXCR4 levels on neutrophils increase after extravasation into injured lungs,possibly through the activation of *** CXCL12/CXCR4 signaling pathway plays an important role in the modulation of neutrophil activity during acute lung injury,not only by promoting chemotaxis but also by suppressing cell death.

关键词： CXCL12 CXCR4 lipopolysaccharides lung injury neutrophils

Development of Algorithm and System for Automatic Generation of Nursing Summaries from Nursing Care Plans

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Intelligent Information Management 2014年第3期6卷 97-103页

作者： Misao Miyagawa Yuko Yasuhara Tetsuya Tanioka hirokazu Ito Motoyuki suzuki Rozzano Locsin Christine E. Lynn College of Nursing Florida Atlantic University Boca Raton USA Department of Nursing Faculty of Health and Welfare Tokushima Bunri University Tokushima Japan Faculty of Information Science and technology Osaka Institute of Technology Osaka Japan Institute of Health Biosciences The University of Tokushima Graduate School Tokushima Japan

A nursing care planning system that automatically generated nursing summaries from information entered into the Psychiatric Outcome Management System (PSYCHOMS?, Tanioka et al.), was developed to enrich the content of nursing summaries at psychiatric hospitals, thereby reducing the workload of nurses. Preparing nursing summaries entails finding the required information in nursing records that span a long period of time and then concisely summarizing this information. This time consuming process depends on the clinical experience and writing ability of the nurse. The system described here automatically generates the text data needed for nursing summaries using an algorithm that synthesizes patient information recorded in electronic charts, the Nursing Care Plan information or the data entered for North American Nursing Diagnosis Association (NANDA) 13 domains with predetermined fixed phrases. Advantages of this system are that it enables nursing summaries to be generated automatically in real time, simplifies the process, and permits the standardization of useful nursing summaries that reflect the course of the nursing care provided and its evaluation. Use of this system to automatically generate nursing summaries will allow more nursing time to be devoted to patient care. The system is also useful because it enables nursing summaries that contain the required information to be generated regardless of who prepares them.

关键词： Nursing Summary Document Nursing Care Plan Automatic Generation PSYCHOMS

Control strategy and methods for continuous direct compression processes

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Asian Journal of Pharmaceutical Sciences 2021年第2期16卷 253-262页

作者： Yasuhiro suzuki hirokazu Sugiyama Manabu Kano Ryutaro Shimono Gosuke Shimada Ryoichi Furukawa Eichi Mano Keiichi Motoyama Tatsuo Koide Yasuhiro Matsui Kazuki Kurasaki Issei Takayama Shunin Hikage Noriko Katori Masahiko Kikuchi Hiroshi Sakai Yoshihiro Matsuda Formulation Technology Research Laboratories Daiichi Sankyo Co.Ltd.Kanagawa 254-0014Japan Department of Chemical System Engineering The University of TokyoTokyo 113-8656Japan Department of Systems Science Kyoto UniversityKyoto 606-8501Japan CMC Sciences Department Regulatory Affairs DivisionR&D DivisionJanssen Pharmaceutical K.K.Tokyo 101-0065Japan EuroTechno Ltd. Kanagawa 223-0057Japan Pharmaceutical Research Department Mitsubishi Tanabe Pharma CorporationOsaka 532-8505Japan Chemical Products CMC Regulatory Affairs Area Japan DevelopmentMSD K.K.Tokyo 102-8667Japan Graduate School of Pharmaceutical Sciences Kumamoto UniversityKumamoto 862-0973Japan Division of Drugs National Institute of Health SciencesKawasaki 210-9501Japan Technology Research&Development Sumitomo Dainippon Pharma Co.Ltd.Osaka 564-0053Japan Formulation Development Department Chugai pharmaceutical Co.Ltd.Tokyo 115-8543Japan Office of New Drug IV Pharmaceuticals and Medical Devices AgencyShin-Kasumigaseki Bldg.Tokyo 100-0013Japan Office of Generic Drugs Pharmaceuticals and Medical Devices AgencyShin-Kasumigaseki Bldg.Tokyo 100-0013Japan KOKANDO Co. Ltd.Toyama 930-8580Japan Pharmaceuticals and Medical Devices Agency Shin-Kasumigaseki Bldg.Tokyo 100-0013Japan

We presented a control strategy for tablet manufacturing processes based on continuous direct *** work was conducted by the experts of pharmaceutical companies,machine suppliers,academia,and regulatory authority in *** different items in the process,the component ratio and blended powder content were selected as the items requiring the control method specific to continuous manufacturing different from the conventional batch *** control and management of the Loss in Weight(LIW)feeder were deemed the most important,and the Residence Time Distribution(RTD)model were regarded effective for setting the control range and for controlling of the LIW *** on these ideas,the concept of process control using RTD was summarized.

关键词： Continuous manufacturing Solid drug products Process control Residence time distribution Loss in weight feeder Regulatory science

Methodology for Developing a Nursing Administration Analysis System

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Intelligent Information Management 2014年第3期6卷 118-128页

作者： Misao Miyagawa Tetsuya Tanioka Yuko Yasuhara Kazuyuki Matsumoto hirokazu Ito Motoyuki suzuki Ren Fuji Rozzano Locsin Department of Nursing Faculty of Health and WelfareTokushima Bunri UniversityTokushimaJapan Institute of Health Biosciences The University of Tokushima Graduate SchoolTokushimaJapan Faculty of Engineering The University of TokushimaTokushimaJapan Faculty of Information Science and Technology Osaka Institute of TechnologyOsakaJapan Christine E.Lynn College of Nursing Florida Atlantic UniversityBoca RatonUSA

Nursing administration requires a large volume of wide-ranging information, and nurse administrators are limited in their ability to compile and analyze information for nursing administration. The purpose of this study is to create methodology for developing a nursing administration analysis system to aid nurse administrators in performing outcome analysis. In this methodology, information required for nursing administration in the PSYCHOMS? (Psychiatric Outcome Management System, registered trademark) database is analyzed according to the individual needs of nurse administrators. It features a combination of a classification method and an extraction method for obtaining quantitative and qualitative data as information required for nursing administration, and enables nurse administrators to easily obtain analysis results that they directly need. This methodology converts the time required nurse administrators to collect and organize information into time for making considerations in order to devise strategies for improving the quality of nursing care services, and can improve the quality and efficiency of nursing administration. This may lead to an increase of the quality of nursing care services at psychiatric hospitals. This methodology is highly versatile as it can be applied in information management, not only for nursing, but for the entire psychiatric hospital.

关键词： Nursing Administration Clinical Pathways Variance Analysis System PSYCHOMS^(█)

X-ray diagnosis with a bloating agent for foreign object ingestion

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World Journal of Clinical Cases 2014年第5期2卷 157-159页

作者： hirokazu Tomishige Zenichi Morise Tatsuya suzuki Fujio Hara Masahito Hibi Takazumi Kato Takashi Hashimoto Department of Surgery Fujita Health University School of MedicineBanbuntane Houtokukai HospitalNagoyaAichi 454-8509Japan Department of Pediatric Surgery Fujita Health University School of MedicineToyoakeAichi 470-1192Japan

The location of an ingested foreign object is often difficult to determine by X-ray if gastric air bubbles are not clear in the *** that provide negative contrast can facilitate precise object localization,which is important for object retrieval and treatment of the *** case report describes a male child,2 years and 2 mo of age,who accidentally swallowed a lithium battery while playing at home.A plain X-ray showed that the battery was in the abdomen,but it was unclear whether the object was still inside the stomach.A second X-ray examination performed after oral administration of a bloating agent to produce expansion of the stomach and provide negative contrast confirmed that the ingested battery was still in the *** battery was then carefully removed using magnetic and balloon catheters under fluoroscopic *** case report describes the successful use of an orally administered bloating agent without pain to the child in orderto determine the precise location of a foreign object in the abdomen.

关键词： Accidental ingestion Bloating agent X-ray Minimal invasion Foreign object

Small undifferentiated intramucosal gastric cancer with lymph-node metastasis:Case report

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World Journal of Gastroenterology 2013年第20期19卷 3157-3160页

作者： Tomoyuki Odagaki Haruhisa suzuki Ichiro Oda Shigetaka Yoshinaga Satoru Nonaka Hitoshi Katai hirokazu Taniguchi Ryoji Kushima Yutaka Saito Endoscopy Division National Cancer Center HospitalTokyo 104-0045Japan Gastric Surgery Division National Cancer Center HospitalTokyo 104-0045Japan Pathology Division National Cancer Center HospitalTokyo 104-0045Japan

It has been reported recently that small undifferentiated intramucosal early gastric cancer(EGC) < 20 mm in size without any lymphovascular involvement or ulcerative findings had virtually no risk of lymph-node(LN) ***,the indications for endoscopic resection were expanded to include such undifferentiated EGC *** describe herein a case of a small undifferentiated intramucosal EGC < 20 mm in size without lymphovascular involvement or ulcerative findings that involved lymph-node metastasis.A 57-year-old female underwent pylorus preserving gastrectomy as standard treatment for an undifferentiated EGC 15 mm in size without any ulcerative *** surgical specimen revealed a signet-ring cell carcinoma with a moderately to poorly differentiated adenocarcinoma limited to the mucosa that was 15 mm in size with no lymphovascular involvement or ulcerative *** case involved LN metastasis,however,and the lesion was diagnosed as pathological stage ⅡA(T1N2M0) according to the Japanese Classification of Gastric Carcinoma.

关键词： Early gastric cancer Endoscopic submucosal dissection Expanded indications Lymph-node metastasis Undifferentiated type