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Flowering-time regulation by the circadian clock:From Arabidopsis to crops

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The Crop Journal 2024年第1期12卷 17-27页

作者： Mingkang Yang Wenjie Lin Yarou Xu Biyu Xie Baiyin Yu Liang Chen Wei huang State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources College of Life SciencesSouth China Agricultural UniversityGuangzhou 510642GuangdongChina henry Fok School of Biology&Agriculture Shaoguan UniversityShaoguan 512005GuangdongChina Guangdong Provincial Key Laboratory of Protein Function and Regulation in Agricultural Organisms South China Agricultural UniversityGuangzhou 510642GuangdongChina Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510642GuangdongChina Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region Shaoguan UniversityShaoguan 512005GuangdongChina

Precise timing of flowering in plants is critical for their growth and reproductive *** factor controlling flowering time is the cycle of light and darkness within a day,known as the *** are classified into long-day,short-day,and day-neutral plants based on light requirements for floral *** the molecular mechanisms that govern this differentiation remain incompletely understood,studies have consistently shown that the circadian clock plays a central role in regulating photoperiod response across diverse plant ***,there is a scarcity of reviews describing the regulatory network linking the circadian clock with photoperiodic *** review summarizes that regulatory network,focusing on the distinct roles of clock genes in long-day and short-day *** also discuss the strategies of clock gene mutations contributing to geographic variation in longday and short-day crops.

关键词： Circadian clock Photoperiod Short-day plants Long-day plants

Efficiency of the motion amplification device with viscous dampers and its application in high-rise buildings

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Earthquake Engineering and Engineering Vibration 2009年第4期8卷 521-536页

作者： henry C.huang WSP Asia Ltd.

After nearly a decade of application and investigation, a motion amplification device with viscous dampers for energy dissipation has been recognized as an effective solution to mitigate wind or seismic excitation, especially for stiff structural systems. As a result of compensation of amplified motion, it has been proved that the efficiency of viscous damper largely depends on the motion amplification device configuration, particularly for device stiflhess. In this paper, a ＂scissor-jack＂ type of motion amplification device, called a ＂toggle brace damper＂ system, is studied. It is demonstrated that the efficiency of such a device reflected by its amplification factor is not merely a function of its geometric configuration, but is highly dependent on the support elements＇ stiffness as well, similar to the mechanism of a leverage arm. Accordingly, a mathematical model in terms of complex modulus of the viscous damper with consideration of the support brace＇s stiffness is established. The results indicate that the efficiency of the motion amplification device with viscous dampers significantly depends on the stiffness of the support elements. Other parameters, such as toggle brace configuration and damping values of the viscous damper, are studied and compared. As an application example, numerical analyses are conducted to study the dynamic performance of a 39-story office tower installed with toggle brace dampers constructed on soft soil in a reclaimed area, under a combined effect of the vortex shedding of an adjacent existing 52-story building and earthquakes. The results show that viscous dampers with a motion amplification system using a properly designed toggle brace device proved to be an effective solution to alleviate the external excitations.

关键词： motion amplification device vibration mitigation viscous damper energy dissipation toggle brace damper

Probing dark matter particles from evaporating primordial black holes via electron scattering in the CDEX-10 experiment

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Science China(Physics,Mechanics & Astronomy) 2024年第10期Mechanics & Astronomy) .卷 87-95页

作者： Zhenhua Zhang Litao Yang Qian Yue Kejun Kang Yuanjing Li Haipeng An Greeshma C. Jianping Chang Yunhua Chen Jianping Cheng Wenhan Dai Zhi Deng Changhao Fang Xinping Geng Hui Gong Qiuju Guo Tao Guo Xuyuan Guo Li he Shengming he Jinwei Hu Hanxiong huang Tuchen huang Lin Jiang S.Karmakar Haubin Li Hanyu Li Jianmin Li Jin Li Qianyun Li Renmingjie Li Xueqian Li Yulan Li Yifan Liang Bin Liao FongKay Lin ShinTed Lin Jiaxuan Liu Shukui Liu Yandong Liu Yu Liu Yuanyuan Liu Hao Ma Yucai Mao Qiyuan Nie Jinhua Ning Hui Pan Ningchun Qi Jie Ren Xichao Ruan Monoj Kumar Singh Tianxi Sun Changjian Tang Yang Tian Guangfu Wang Junzheng Wang Li Wang Qing Wang Yufeng Wang Yunxiang Wang henry Tsz-King Wong Shiyong Wu Yucheng Wu Haoyang Xing Rui Xu Yin Xu Tao Xue Yulu Yan Nan Yi Chunxu Yu Haijun Yu Jianfeng Yue Ming Zeng Zhi Zeng Bingtao Zhang Fengshou Zhang Lei Zhang Zhenyu Zhang Jizhong Zhao Kangkang Zhao Minggang Zhao Jifang Zhou Zuying Zhou Jingjun Zhu CDEX Collaboration Key Laboratory of Particle and Radiation Imaging (Ministry of Education) and Department of Engineering Physics Tsinghua University Department of Physics Tsinghua University Institute of Physics Academia Sinica NUCTECH Company YaLong River Hydropower Development Company College of Nuclear Science and Technology Beijing Normal University College of Physics Sichuan University School of Physics Peking University Department of Nuclear Physics China Institute of Atomic Energy Sino-French Institute of Nuclear and Technology Sun Yet-sen University School of Physics Nankai University Department of Physics Banaras Hindu University Department of Physics Beijing Normal University

Dark matter（DM） is a major constituent of the ***,no definite evidence of DM particles（denoted as “χ”） has been found in DM direct detection（DD） experiments to *** is a novel concept of detectingχfrom evaporating primordial black holes（PBHs）.We search forχemitted from PBHs by investigating their interaction with target *** examined PBH masses range from 1×1015to 7×1016g under the current limits of PBH abundance *** 205.4 kg·day data obtained from the CDEX-10 experiment conducted in the China Jinping Underground Laboratory,we exclude the χ-electron（χ-e） elastic-scattering cross section σχe～5×10-29cm2for χ with a mass ■ keV from our *** the higher radiation background but lower energy threshold（160 eV）,CDEX-10 fills a part of the gap in the previous *** (mχ,σχe) can be determined in the future,DD experiments are expected to impose strong constraints on fPBHfor large MPBHs.

关键词： CDEX primordial black hole light dark matter particle dark matter-electron scattering high purity germanium detector

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Conditional Coverage Estimation for High-Quality Prediction Intervals

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Journal of Systems Science and Systems Engineering 2023年第3期32卷 289-319页

作者： Ziyi huang henry Lam Haofeng Zhang School of Engineering and Applied Science Columbia UniversityNew YorkNY 10027USA

Deep learning has been recently studied to generate high-quality prediction intervals(PIs)for uncertainty quantification in regression tasks,including recent applications in simulation *** high-quality criterion requires PIs to be as narrow as possible,whilst maintaining a pre-specified level of data(marginal)***,most existing works for high-quality PIs lack accurate information on conditional coverage,which may cause unreliable predictions if it is significantly smaller than the marginal *** address this problem,we propose an end-to-end framework which could output high-quality PIs and simultaneously provide their conditional coverage *** doing so,we design a new loss function that is both easy-to-implement and theoretically justified via an exponential concentration *** evaluation on real-world benchmark datasets and synthetic examples shows that our approach not only achieves competitive results on high-quality PIs in terms of average PI width,but also accurately estimates conditional coverage information that is useful in assessing model uncertainty.

关键词： Uncertainty quantification prediction intervals conditional coverage neural networks calibrationerror

Unsupervised spectral feature selection algorithms for high dimensional data

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Frontiers of Computer Science 2023年第5期17卷 27-40页

作者： Mingzhao WANG henry HAN Zhao huang Juanying XIE School of Computer Science Shaanxi Normal UniversityXi’an 710119China Department of Computer Science School of Engineering&Computer ScienceBaylor UniversityWacoTX 76798USA

It is a significant and challenging task to detect the informative features to carry out explainable analysis for high dimensional data,especially for those with very small number of *** selection especially the unsupervised ones are the right way to deal with this challenge and realize the ***,two unsupervised spectral feature selection algorithms are proposed in this *** group features using advanced Self-Tuning spectral clustering algorithm based on local standard deviation,so as to detect the global optimal feature clusters as far as *** two feature ranking techniques,including cosine-similarity-based feature ranking and entropy-based feature ranking,are proposed,so that the representative feature of each cluster can be detected to comprise the feature subset on which the explainable classification system will be *** effectiveness of the proposed algorithms is tested on high dimensional benchmark omics datasets and compared to peer methods,and the statistical test are conducted to determine whether or not the proposed spectral feature selection algorithms are significantly different from those of the peer *** extensive experiments demonstrate the proposed unsupervised spectral feature selection algorithms outperform the peer ones in comparison,especially the one based on cosine similarity feature ranking *** statistical test results show that the entropy feature ranking based spectral feature selection algorithm performs *** detected features demonstrate strong discriminative capabilities in downstream classifiers for omics data,such that the AI system built on them would be reliable and *** is especially significant in building transparent and trustworthy medical diagnostic systems from an interpretable AI perspective.

关键词： feature selection spectral clustering feature ranking techniques entropy cosine similarity

不同区域神经阻滞对胸腔镜肺癌根治术患者阿片类药物用量和应激反应的影响

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中国临床研究 2024年第1期37卷 61-65页

作者：黄益波王梅芳贺腾濮健峰常熟市第二人民医院麻醉科江苏苏州215500

目的探讨胸腔镜肺癌根治术患者进行超声引导下前锯肌平面阻滞(SAPB)与胸椎旁神经阻滞(TPVB)对阿片类药物用量和应激反应的影响。方法选取2019年6月至2022年1月于常熟市第二人民医院择期接受胸腔镜肺癌根治术的患者130例,根据随机数字表... 详细信息

目的探讨胸腔镜肺癌根治术患者进行超声引导下前锯肌平面阻滞(SAPB)与胸椎旁神经阻滞(TPVB)对阿片类药物用量和应激反应的影响。方法选取2019年6月至2022年1月于常熟市第二人民医院择期接受胸腔镜肺癌根治术的患者130例,根据随机数字表法分为SAPB组65例和TPVB组65例。麻醉诱导前,SAPB组进行超声引导下SAPB,TPVB组进行超声引导下TPVB,术后均连接镇痛泵给予静脉自控镇痛。将术前、关闭胸腔时、术后2 h、6 h和24 h等时间点分别设为T_(1)、T_(2)、T_(3)、T_(4)和T_(5),记录两组术中出血量、术中补液量、手术时间、术中舒芬太尼及丙泊酚用量和术后T_(3)、T_(4)和T_(5)舒芬太尼累积使用量;分别于T_(3)、T_(4)和T_(5)采用Prince-henry评分评估两组疼痛变化,酶联免疫法检测前列腺素E_(2)(PGE_(2))、去甲肾上腺素(NE)和皮质醇(Cor)水平,血气分析仪检测动脉血氧分压,计算氧合指数(OI);记录两组术后不良事件发生情况。结果T_(3)~T_(5)时间点,SAPB组PGE_(2)、NE和Cor水平显著低于TPVB组(P0.05)。SAPB组恶心呕吐(6.15%vs 18.46%,χ^(2)=4.561,P=0.033)、肺不张(3.08%vs 12.31%,χ^(2)=3.900,P=0.048)和低血压(7.69%vs 20.00%,χ^(2)=4.127,P=0.042)发生率均低于TPVB组。结论在超声引导下,与TPVB比较,SAPB可缓解胸腔镜肺癌根治术患者应激反应,促进肺氧合功能恢复,减少术后不良事件。但能否显著降低阿片类药物用量,有待进一步探讨。

关键词：超声引导前锯肌平面阻滞胸椎旁神经阻滞胸腔镜肺癌根治术阿片类药物应激反应

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双氰基二苯代乙烯型双光子荧光温度敏感探针

精细化工 2024年第4期41卷 804-809页

作者：黄池宝王谦遵义师范学院信息工程学院贵州遵义563002 中国科学院地球化学研究所环境地球化学国家重点实验室贵州贵阳550002 韶关大学英东生物与农业学院广东韶关512005

对二甲苯分别经过亲电取代、亲核取代、α-位溴代和亲核取代消除反应得到1,4-二氰基-2-甲基-5-(二乙基磷酰基甲基)苯(Ⅴ);咔唑经过亲核取代反应得到中间体4-(9-咔唑基)-苯甲醛(Ⅶ);中间体Ⅴ与Ⅶ经维蒂希-霍纳尔反应得到目标化合物2,5-... 详细信息

对二甲苯分别经过亲电取代、亲核取代、α-位溴代和亲核取代消除反应得到1,4-二氰基-2-甲基-5-(二乙基磷酰基甲基)苯(Ⅴ);咔唑经过亲核取代反应得到中间体4-(9-咔唑基)-苯甲醛(Ⅶ);中间体Ⅴ与Ⅶ经维蒂希-霍纳尔反应得到目标化合物2,5-二氰基-4-甲基-4′-(9-咔唑基)二苯乙烯(供体-π-受体,D-π-A)(SP),反应总产率达45.5%。SP的溶剂生色范围由412 nm(环己烷)红移至541 nm(二甲基亚砜)(最大发射波长),SP具有非常大的双光子吸收截面(δTPA=6930 GM)和高的荧光量子产率[Φ=0.992(环己烷)],其荧光强度对溶剂极性和温度显示很强的依赖性。在单光子荧光发射(OPE)和双光子荧光发射(TPE)谱图中,SP的单、双光子荧光发射强度与温度之间的线性相关系数(R^(2))均>0.998,表达式分别为IF=–0.0141θ+1.2881(OPE)和IF=–0.0143θ+1.2698(TPE)[IF为荧光强度,θ为温度(℃)]。

关键词：溶剂生色二苯代乙烯双光子激发环境敏感探针咔唑功能材料

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Impact of meteorological factors on the incidence of childhood hand,foot,and mouth disease(HFMD)analyzed by DLNMs-based time series approach

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Infectious Diseases of Poverty 2018年第1期7卷 77-86页

作者： Hongchao Qi Yue Chen Dongli Xu Hualin Su Longwen Zhan Zhiyin Xu Ying huang Qianshan he Yi Hu henry Lynn Zhijie Zhang Department of Epidemiology and Biostatistics School of Public HealthFudan UniversityShanghai 20002China Key Laboratory of Public health Safety Ministry of EducationShanghai 200032China Collaborative Innovation Center of Social Risks Governance in health School of Public HealthFudan UniversityShanghai 200032China School of Epidemiology Pubic Health and Preventive MedicineFaculty of MedicineUniversity of Ottawa451 Smyth RdOttawaON 10610Canada Minghang District Center for Disease Control and Prevention Shanghai 201101China Shanghai Meteorological Service Shanghai 201499China Shanghai Key Laboratory of Meteorology and health Shanghai 201499China

Background:Hand,foot,and mouth disease(HFMD)has become an emerging infectious disease in China in the last *** has been evidence that meteorological factors can influence the HFMD incidence,and understanding the mechanisms can help prevent and control ***:HFMD incidence data and meteorological data in Minhang District,Shanghai were obtained for the period between 2009 and *** lag non-linear models(DLNMs)were utilized to investigate the impact of meteorological factors on HFMD incidence after adjusting for potential confounders of long time trend,weekdays and ***:There was a non-linear relationship between temperature and HFMD incidence,the RR of 5th percentile compared to the median is 0.836(95%CI:0.671-1.042)and the RR of 95th percentile is 2.225(95%CI:1.774-2.792),and the effect of temperature varied across age *** incidence increased with increasing average relative humidity(%)(RR=1.009,95%CI:1.005-1.015)and wind speed(m/s)(RR=1.197,95%CI:1.118-1.282),and with decreasing daily rainfall(mm)(RR=0.992,95%CI:0.987-0.997)and sunshine hours(h)(RR=0.966,95%CI:0.951-0.980).Conclusions:There were significant relationships between meteorological factors and childhood HFMD incidence in Minhang District,*** information can help local health agencies develop strategies for the control and prevention of HFMD under specific climatic conditions.

关键词： Hand foot and mouth disease Meteorological factor Distributed lag non-linear model

Evaluation of plant seed DNA and botanical evidence for potential forensic applications

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Forensic Sciences Research 2020年第1期5卷 55-63页

作者： Cheng-Lung Lee Yi-Hsin huang Ian CHsu henry CLee Department of Criminal Investigation Taiwan Police CollegeTaiwanChina Crime Scene Theater Qatar Police CollegeDohaQatar Institute of Business and Management National Chiao Tung UniversityTaiwanChina Department of Biomedical Engineering and Environmental Sciences National Tsing Hua UniversityTaiwanChina Forensic Science Program University of New HavenWest HavenCTUSA

Seeds,the reproductive organs of plants,are common as trace evidence from crime *** evidence could be grouped into several categories based on the types of crimes they are associated with,including child abuse,homicides and *** commonly,seeds are examined microscopically and identified to the plant species level to show a linkage between persons and *** recently,forensic researchers have evaluated the poten-tial for extracting and typing DNA from seeds to further individualize the *** a model system,tomato seeds were examined microscopically after different cooking treat-ments and assessed for the potential to DNA type seeds for variety identification.A sufficient quantity and quality of DNA were recovered from uncooked,digested and undigested tomato seeds for amplified fragment length polymorphism(AFLP)analysis;however,any form of cooking destroyed the seed DNA.A simple microscopic analysis was able to distin-guish between a cooked tomato seed versus an uncooked *** article is intended to provide an overview of case examples and current techniques for the forensic examination of seeds as plant-derived evidence.

关键词： Forensic sciences forensic botany tomato seed DNA extraction crime scene non-human evidence AFLP STR