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Chinese Journal of Polymer Science 2018年第12期36卷 1353-1360页

作者： heng-xue Xiang Fatemeh Zabihi Xu-Zhen Zhang Mei-Fang Zhu State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and Engineering Donghua University The Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education College of Materials and Textile Zhejiang SciTech University

A series of cross-linked poly（3-hydroxybutyrate-co-3-hydroxyvalerate）/octavinyloctasilasesquioxane （PHBWOVS） composites were obtained by a simple melt reactive processing technique. Dicumyl peroxide （DCP） and OVS were employed as a free radical initiator and a cross-linking agent, respectively. The chemical structure of these produced composites were identified by 1H/13C/29Si-nuclear magnetic resonance spectroscopy （1H/13C/29Si-NMR） and Fourier transform infrared spectroscopy （FTIR）. The melting behavior, non-isothermal crystallization, spherulite morphology and thermal stability property of PHBV/OVS composites were also investigated. The nucleation behaviors and crystallization rate of PHBV/OVS were significantly enhanced with the formation of cross-linked networks with different side-chains and cross-linking points. The red shift of crystalline peak temperature with addition of a small amount of OVS content evidenced the higher crystalline ability compared with the neat PHBV. However there was a threshold content, beyond which the crystallization rate weakened again. Additionally, the cross-linked structure of PHBV/OVS composites could be adjusted by changing the amount of OVS.

关键词： Biodegradable PHBV Reactive processing Crystallization behavior Composite

TiO_2/NaY Composite as Photocatalyst for Degradation of Omethoate

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Chemical Research in Chinese Universities 2009年第4期25卷 543-549页

作者： ZHAO Di-shun WANG Jia-lei ZHAO xue-heng ZHANG Juan School of Chemistry and Pharmaceutical Engineering Hebei University of Science and Technology Shijiazhuang 050018 P R. China Cincinnati Children＇s Hospital Medical Center Cincinnati OH 45229 USA School of Chemical Engineering and Technology Tianjin University Tianjin 300072 P. R. China

Photocatalytic activities of TiO2 and NaY zeolites-supported TiO2 were investigated with omethoate as a model *** physical and chemical states of NaY zeolite-supported TiO2 were evaluated via XRD,FTIR,BET and *** of omethoate was studied with H2O2 as oxidant and TiO2 supported on NaY zeolite as *** involved in the photo-catalysis of omethoate,i.e.,the calcination temperature of the photocatalyst,initial omethoate concentration,the amount of TiO2 loaded on NaY zeolite,photocatalyst dosage and H2O2 concentration were investigated in *** results show that TiO2/NaY zeolite prepared by means of sol-gel method exhibited a good photocatalytic activity for the degradation of *** conditions included the calcination temperature of photocatalyst 550℃,initial omethoate concentration 500 mg/L,the amount of TiO2 loaded on NaY zeolite 35%（mass fraction）,the amount of photocatalyst 5 g/L,H2O2 concentration 30 mL/L and an irradiation time of 180 *** removal of omethoate was up to 93%.Kinetics parameters of the photocatalytic degradation of omethoate were measured and *** result shows the kinetics of photocatalytic degradation of omethoate is first-order.

关键词： TiO2 NaY zeolite Photocatalytic degradation Omethoate

Multi-frequency point supported LLRF front-end for CiADS wide-bandwidth application

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Nuclear Science and Techniques 2020年第3期31卷 66-73页

作者： Qi Chen Zheng Gao Zheng-Long Zhu Zong-heng xue Yuan He Xian-Wu Wang Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China

The China initiative Accelerator Driven System,CiADS,physics design adopts 162.5 MHz,325 MHz,and 650 MHz cavities,which are driven by the corresponding radio frequency(RF)power system,requiring frequency translation front-end for the RF *** that application,a general-purpose design front-end prototype has been developed to evaluate the multi-frequency point supported design *** difficult parts to achieve the requirements of the general-purpose design are reasonable device selection and balanced *** a carefully selected low-noise wide-band RF mixer and amplifier to balance the performance of multi-frequency supported down-conversion,specially designed LO distribution net to increase isolation between adjacent channels,and external band-pass filter to realize expected up-conversion frequencies,high maintenance and modular front-end generalpurpose design has been *** of standard parameters show an R2 value of at least 99.991%in the range of-60-10 dBm for linearity,up to 18 dBm for P1dB,and up to 89 dBc for cross talk between adjacent *** phase noise spectrum is lower than 80 dBc in the range of 0-1 MHz;cumulative phase noise is 0.006°;and amplitude and phase stability are 0.022%and 0.034°,respectively.

关键词： Frequency jump RF Front-end LLRF CiADS

Efficacy and safety of extracorporeal membrane oxygenation for burn patients: a comprehensive systematic review and meta-analysis

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Burns & Trauma 2023年第1期11卷 91-104页

作者： xue heng Peng Cai Zhiqiang Yuan Yizhi Peng Gaoxing Luo Haisheng Li Institute of Burn Research State Key Laboratory of TraumaBurns and Combined InjurySouthwest HospitalThird Military Medical University(Army Medical University)Chongqing400038China Department of Intensive Care Medicine PLA 80th Group Army HospitalWei Fang CityShan Dong Province261000China

Background:Respiratory and circulatory dysfunction are common complications and the leading causes of death among burn patients,especially in severe burns and inhalation ***,extracorporeal membrane oxygenation(ECMO)has been increasingly applied in burn ***,current clinical evidence is weak and *** study aimed to comprehensively evaluate the efficacy and safety of ECMO in burn ***:A comprehensive search of PubMed,Web of Science and Embase from inception to 18 March 2022 was performed to identify clinical studies on ECMO in burn *** main outcome was in-hospital *** outcomes included successful weaning from ECMO and complications associated with ***-analysis,meta-regression and subgroup analyses were conducted to pool the clinical efficacy and identify influencing ***:Fifteen retrospective studies with 318 patients were finally included,without any control *** commonest indication for ECMO was severe acute respiratory distress syndrome(42.1%).Veno-venous ECMO was the commonest mode(75.29%).Pooled in-hospital mortality was 49%[95%confidence interval(CI)41-58%]in the total population,55%in adults and 35%in ***-regression and subgroup analysis found that mortality significantly increased with inhalation injury but decreased with ECMO *** studies with percentage inhalation injury≥50%,pooled mortality(55%,95%CI 40-70%)was higher than in studies with percentage inhalation injury<50%(32%,95%CI 18-46%).For studies with ECMO duration≥10 days,pooled mortality(31%,95%CI 20-43%)was lower than in studies with ECMO duration<10 days(61%,95%CI 46-76%).In minor and major burns,pooled mortality was lower than in severe *** percentage of successful weaning from ECMO was 65%(95%CI 46-84%)and inversely correlated with burn *** overall rate of ECMO-related complications was 67.46%,and infection(30.77%)and bleedings(23.08%)were the two most common complicati

关键词： Extracorporeal membrane oxygenation Burns Acute respiratory distress syndrome Inhalation injury

Overexpression of YOD1 Promotes the Migration of Human Oral Keratinocytes by Enhancing TGF-β3 Signaling

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Biomedical and Environmental Sciences 2018年第7期31卷 499-506页

作者： JU Qiang LI Meng xue CHEN Gang WANG heng xue SHI Qiao Mei GE Xing DING Zhen WANG Qi XU Li Chun School of Public Health Xuzhou Medical University

Objective To investigate the effects of YOD1 overexpression on the proliferation and migration of human oral keratinocytes（HOKs）, and to clarify whether the mechanisms involve transforming growth factor-β（TGF-β） signaling. Methods HOKs were transfected with the plasmid p EGFP-N3-YOD1 containing YOD1. The mR NA levels of YOD1 and TGF-β were determined by q PCR. The protein expressions of YOD1, TGF-β, Smad2/3, Smad4, and phospho-Smad2/3 were determined by western blotting. Cell proliferation and migration were evaluated by Cell Counting Kit-8 assay and wound healing assay, respectively. Results The m RNA and protein levels of YOD1 were higher in HOKs transfected with YOD1. YOD1 overexpression significantly enhanced the migration of HOKs. The mR NA and protein levels of TGF-β3 were increased by YOD1 overexpression. HOKs transfected with YOD1 exhibited increased phospho-Smad2/3 levels. Conclusion YOD1 overexpression enhances cell migration by promoting TGF-β3 signaling which may play an important role in lip and palate formation. YOD1 mutation may contribute to aberrant TGF-β3 signaling associated with decreased cell migration resulting in NSCLP.

关键词： Non-syndromic cleft lip and palate De-ubiquitinating enzyme YOD1 Transforming growthfactor-β Smads Cell migration

Effects of real-time traffic information systems on traffic performance under different network structures

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Journal of Central South University 2012年第2期19卷 586-592页

作者： YAO xue-heng F.Benjamin ZHAN LU Yong-mei YANG Min-hua School of Geosciences and Info-Physics Central South University Texas Center for Geographic Information Science Department of GeographyTexas State University-San Marcos

The effects of real-time traffic information system(RTTIS)on traffic performance under parallel,grid and ring networks were *** simulation results show that the effects of the proportion of RTTIS usage depend on the road network *** traffic on a parallel network,the performance of groups with and without RTTIS level is improved when the proportion of vehicles using RTTIS is greater than 0 and less than 30%,and a proportion of RTTIS usage higher than 90%would actually deteriorate the *** both grid and ring networks,a higher proportion of RTTIS usage always improves the performance of groups with and without *** all three network structures,vehicles without RTTIS benefit from some proportion of RTTIS usage in a system.

关键词： real-time traffic information traffic network traffic efficiency optimization of urban traffic

Facile Synthesis of High Molecular Weight Polypeptides via Fast and Moisture Insensitive Polymerization of a-Amino Acid N-Carboxyanhydrides

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Chinese Journal of Polymer Science 2020年第10期38卷 1131-1140,I0007页

作者： Yue Ming Wu Wei-Wei Zhang Rui-Yi Zhou Qi Chen Chen-Yu Xie heng-xue Xiang Bin Sun Mei-Fang Zhu Run-Hui Liu State KeyLaboratory of Bioreactor Enginering East China Uniersity of Science and TechnologyShanghai 200237China State Key Laboratory for Modification of Chemical Fibers and Polymer Materals College of Materias Science and EngineringDonghua UniversityShanghai 201620China Key Laboratory of Specally Functional Polymeric Materials and Related Technology(ECUST)Ministry of Education Key Laboratory for Ultrafine Materials of Ministry of EducationResearch Center for Biomedical Materials of Ministry of EducationSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai 200237China

Polypeptides have been widely utilized in the fields of biomaterials and *** since N-carboxyanhydride(NCA)was reported by Hermann Leuchs in 1906,ring-opening polymerization of NCAS has been extensively used to prepare *** continuous innovations,it is still challenging to synthesize polypeptides in high molecular weight *** address this challenge,we developed KHMDS/NaHMDS initiated fast NCA polymerization that is also moisture tolerant,open-flask amenable and terminal *** NCA polymerization was able to proceed in most common solvents and meet the solubility requirement of variable NCA monomers and corresponding *** can initiate r benzy-L glutamate-N carboxyanhydride(BLG NCA)polymerization in a reaction rate 92 times faster than does hexylamine and 80 times faster than does *** NCA polymerization also demonstrated easy and fast synthesis of gram-scale long chain polypeptides in an open flask.

关键词： NCA polymerization Polypeptide Open vessel Fast polymerization High Mw

Molecular characterization of an IL-1β gene from the large yellow croaker（Larimichthys crocea） and its effect on fish defense against Vibrio alginolyticus infection

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Zoological Research 2015年第3期36卷 133-141页

作者： Jun WU Yu-Hong SHI xue-heng ZHANG Chang-Hong LI Ming-Yun LI Jiong CHEN Laboratory of Biochemistry and Molecular Biology School of Manne Sciences Ningbo University Ningbo 315211 China Donghai Sea Collaborative Innovation Center for Industrial Upgrading Mariculture Ningbo University Ningbo 315211 China

Interleukin 1β（IL-1β）, the first interleukin to be characterized, plays a key role in regulating the immune response. In this study, we determined the c DNA and genomic DNA sequences of the IL-1β gene from the large yellow croaker, Larimichthys crocea. Phylogenetic analysis indicated that the IL-1β（Lc IL-1β） gene was most closely related to that of European seabass（Dicentrarchus labrax）, sharing 67.8% amino acid identity. In healthy large yellow croaker, Lc IL-1β transcription was detected in all tested tissues, with the highest level found in the head kidney. Upon Vibrio alginolyticus infection, Lc IL-1β transcription in all tested tissues was significantly upregulated. Intraperitoneal injection of recombinant Lc IL-1β（r Lc IL-1β） improved the survival rate and reduced the tissue bacterial load after V. alginolyticus infection. In addition, r Lc IL-1β induced monocytes/macrophages（MO/MΦ） chemotaxis and increased phagocytosis and bactericidal activity in vitro. These results suggest that Lc IL-1β plays an important role in the large yellow croaker immune response against V. alginolyticus.

关键词： Interleukin 1β Large yellow croaker Survival rate Vibrio alginolyticus Monocytes/macrophages

Design and high-power testing of offline conditioning cavity for CiADS RFQ high-power coupler

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Nuclear Science and Techniques 2024年第9期35卷 18-27页

作者： Ruo-Xu Wang Yuan He Long-Bo Shi Chen-Xing Li Zong-heng xue Tian-Cai Jiang Xian-Bo Xu Lie-Peng Sun Zhou-Li Zhang Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Lanzhou University Lanzhou 730000China

To validate the design rationality of the power coupler for the RFQ cavity and minimize cavity contamination,we designed a low-loss offline conditioning cavity and conducted high-power *** offline cavity features two coupling ports and two tuners,operating at a frequency of 162.5 MHz with a tuning range of 3.2 *** the installation angle of the coupling ring and the insertion depth of the tuner helps minimize cavity *** performed electromagnetic structural and multiphysics simulations,revealing a minimal theoretical power loss of 4.3%.However,when the cavity frequency varied by110 kHz,theoretical power losses increased to10%,necessitating constant tuner adjustments during *** simulations indicated that increased cavity temperature did not affect frequency *** completion of the offline high-power conditioning platform,we measured the transmission performance,revealing a power loss of 6.3%,exceeding the theoretical *** utilized efficient automatic range scanning and standing wave resonant *** fully condition the power coupler,a 15°phase difference between two standing wave points in the condition-ing system was ***,the maximum continuous wave power surpassed 20 kW,exceeding the expected target.

关键词： RFQ cavity Power coupler Offline conditioning Resonant cavity

Small Bowel Obstruction Secondary to Obturator Hernia Preoperatively Diagnosed by Ultrasound

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Chinese Medical Journal 2016年第4期129卷 490-491页

作者： heng xue Ying Fu Li-Gang Cui Department of Ultrasound Peking University Third Hospital Beijing 100191 China

To the Editor： A frail 74-year-old woman visited the emergency department with a chief complaint of＂intermittent abdominal pain for 6 days and vomiting for 2 days＂. She described her symptoms as a colicky lower abdominal pain that occurred 6 days ago, recurred several times, and resolved spontaneously, but progressed to severe and sustained pain with vomiting 2 days bet＇ore visiting the hospital. The lower abdominal pain also radiated down to the right medial thigh. Physical examination of the abdomen revealed distention, with intestinal pattern and positive bowel sounds. Tenderness on tile lower abdomen was identified, which radiated to the right medial thigh. There was no palpable mass in the abdominal or groin area.

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