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CRKL and CK2 <i>β</i>over Expression Are Independent Predictors of Patients survival in Endometrioid Endometrial Carcinoma

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Open Journal of Obstetrics and Gynecology 2019年第4期9卷 479-493页

作者： Randa Mohamed Kaf Wafaa el-Beshbishi Ahmed A. Obaya Rham Z. Ahmed Khaled Fathy helal Mohamed sH. Ramadan Abdelwahab s. Almoregy Ibrahim A. Heggy Ola A. Harb Department of Pathology Faculty of Medicine Zagazig University Zagazig Egypt Department of Clinical Oncology and Nuclear Medicine Faculty of Medicine Mansoura University Mansoura Egypt Department of Clinical Oncology and Nuclear Medicine Faculty of Medicine Zagazig University Zagazig Egypt Department of Medical Oncology Faculty of Medicine Zagazig University Zagazig Egypt Department of Gynecology & Obstetrics Faculty of Medicine Zagazig University Zagazig Egypt Department of General surgery Faculty of Medicine Zagazig University Zagazig Egypt

Context: The prognostic significance of expression of V-Crk avian sarcoma virus CT10 oncogene homolog-like (CRKL) and Protein kinase CK2 β in endometroid carcinoma is not fully clarified. Aim: To assess the prognostic values and clinicopathological roles of CRKL and CK2 β expression in endometroid carcinoma by correlation their expression levels with clinicopathological parameters, response to therapy, and recurrence of the tumor and patients survival. settings: Faculty of Medicine, Zagazig University, and Mansoura University. Methods: CRKL and CK2 β expressions were evaluated in 50 paraffin blocks EC patients that were followed up for 5 years. The relationship between their level of expressions, clinicopathological criteria and prognosis of patients was analyzed. statistical analysis used: sPss 22.0 for windows (sPss Inc., Chicago, IL, UsA) and MedCalc windows (software bvba 13, Ostend, Belgium). Results: High expression of CRKL and CK was positively correlated with higher grade of the tumor (p = 0.004 and 0.006 respectively), presence of L.N metastases (p = 0.009 and 0.003 respectively), presence of distant metastases (p = 0.029 and 0.003 respectively) and advanced FIGO stage (p 0.001), poor response to therapy (p = 0.046 and 0.005 respectively), higher incidence of recurrence of the tumor after therapy (p = 0.004 and 0.048 respectively), higher incidence of cancer progression p = 0.018 and 0.044 respectively), poor PFs (p = 0.008 and 0.013 respectively), and Os rates

关键词： CRKL CK2 β Endometroid Carcinoma Immunohistochemistry Prognosis

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The Three Page Guide to the Most Important Results of M. s. el Naschie’s Research in E-Infinity Quantum Physics and Cosmology

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Open Journal of Microphysics 2013年第4期3卷 141-145页

作者： M. A. helal L. Marek-Crnjac Ji-Huan He Department of Math Cairo University Egypt National Engineering Laboratory for Modern silk College of Textile and Clothing Engineering Soochow University Suzhou China Technical school Center of Maribor Maribor Slovenia

In this short survey, we give a complete list of the most important results obtained by el Naschie’s E-infinity Cantorian space-time theory in the realm of quantum physics and cosmology. special attention is paid to ... 详细信息

关键词： Review of E-infinity summary of Cantorian space-Time el Naschie Nottale and Ord Fractal space-Time Rindler space-Time Revising Einstein Theory Dark Energy Revealed

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UV/O<sub>3</sub>Preirradiated Cotton Fabric-Containing Chitosan for Effective Removal of Heavy Metals

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Materials sciences and Applications 2014年第10期5卷 698-707页

作者： A. Hebeish Kh. elnagar M. H. helal M. s. Ragab M. F. shaaban Chemistry Department Faculty of Science Helwan University Cairo Egypt Textile Metrology Laboratory National Institute for Standards (NIS) Giza Egypt Textile Research Division National Research Centre (NRC) Giza Egypt

The present work aims at studying the effect of Ultra-Violet/Ozone (UV/O3) irradiation of cotton fabrics on their interaction with chitosan/citric acid based formulation and, the onset of this on the ability of treated fabrics to remove heavy metal ions from their aqueous solutions. To achieve the goal, the cotton fabrics were preirradiated for 90 minutes using UV/O3 as radiation source. The irradiated and the unirrdadiated cotton fabrics were submitted to finishing formulation consisting essentially of chitosan as a finishing agent and citric acid as crosslinking agent in combination with sodium hypophosphite (sHP) as a catalyst. Finishing formulation containing different concentrations of chitosan (0 - 4) along with citric acid (8 g/l) and sHP (4 g/l) were used and the interaction of chitosan with the cotton fabric was assessed through nitrogen measurement. The preirradiated and chemically finished fabrics vis-à-vis the unirrdadiated fabrics were examined for metal ion removal. Results conclude that the preirradiated cotton fabrics exhibit higher nitrogen content than the unirrdadiated fabrics. The same holds true for heavy metal removal, exemplified by Zn2+ and Cd2+ ions from their aqueous solutions. That is, preirradiated fabrics containing chitosan display higher percent heavy metal removal than their unirrdadiated mates.

关键词： Chitosan Cotton Irradiation Preirradiation Heavy Metal Removal

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The Hepatoprotective Effects of solanum Incanum on Acetaminophen-lnduced Hepatotoxicity in Guinea Pigs

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Journal of Life sciences 2010年第5期4卷 44-48页

作者： Yahya saleh Al-Awthan Mohammed A. salama Ahmed M. helal Department of Biology Faculty of Science Ibb University Ibb 70270 Yemen Department of Zoology Faculty of Science Al-Azhar University Cairo 1150049 Egypt Department of Zoology Faculty of Science Al-Zaqaziq University Banha 44519 Egypt

solanum incanum, a shrubby herb, is widely distributed and used as analgesic, antitoxic, and antispasmodic in folk medicine. In the present study, the protective effects of aqueous extract of s. incanum against acetaminophen induced acute liver damage were evaluated in guinea pigs. Animals were orally administered with s. incanum extract （50 and 100 mg/ kg bw） and silymarin （ 100 mg / kg bw） respectively for 6 days followed by acetaminophen administration （2 g / kg bw） at the 7th day. The results showed that the treatment with s. incanum extract significantly lowered the acetaminophen-induced serum levels of hepatic marker enzymes （AsT, ALT, and ALP）, Liver histopathology also showed that s. incanum extract reduced the incidence of liver lesions including the swelling of hepatic cells, lymphocytes infiltration, nucleus condensation, and hepatic necrosis induced by acetaminophen treatment in guinea pigs. The s. incanum extract at a dose of 100 mg / kg bw was more effective in suppressing the oxidative damage than the extract at a dose of 50 mg / kg bw. Therefore, the results of this study suggest that s. incanum extract could protect liver against the acetaminophen-induced oxidative damage.

关键词： solanum incanum extract acetaminophen hepatoprotection guinea pigs

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Carbon Turnover in a Crop Rotation Under Free Air CO_2 Enrichment (FACE)

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Pedosphere 2005年第6期15卷 728-738页

作者： H. J. WEIGel A. PACHOLsKI s. BURKART M. helal O. HEINEMEYER B. KLEIKAMP R. MANDERsCHEID C. FRüHAUF G. F. HENDREY K. LEWIN J. NAGY Institute of Agroecology Federal Agricultural Research Centre (FAL) Bundesallee 50 38116 Braunschweig (Germany). German Weather service Agriculture Department Kreuzweg 25 65366 Geisenheim (Germany) Earth systems sciences Division Brookhaven National Laboratory Building 490D P.O. Box 5000 Upton NY 11973 (USA)

Mostly based on assumptions derived from controlled-environment studies, predicted future atmospheric CO2 concentrations [CO2] are expected to have considerable impacts on carbon （C） turnover in agro-ecosystems. In order to allow the in situ examination of C-transformations in the plant-soil system of arable crop rotations under future [002], a free air carbon dioxide enrichment （FACE） experiment （550 μmol mol^-1 CO2） was started at Braunschweig, Germany in 1999. The crop rotation under investigation comprised winter barley, a cover crop （ryegrass）, sugar beets and winter wheat. Assessments of CO2 effects included the determination of above- and belowground biomass production, measurements of canopy CO2- and H2O- fluxes, soil microbial biomass and in situ soil respiration. The results obtained during the 1st crop rotation cycle （3 years） showed that for the selected crops elevated [CO2] entailed significant positive effects （P 〈 0.05） on aboveground （6%-14% stimulation） and belowground biomass production （up to 90% stimulation）, while canopy evapotranspiration was reduced. This resulted in increased soil water content. Also, depending on crop type and season, high CO2 stimulated in situ soil respiration （up to 30%）, while soil microbial biomass did not show significant respouses to elevated [CO2] during the first rotation cycle.

关键词： agroecosystems carbon elevated CO2 FACE soil

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Time to integrate“One Health Approach”into nanoplastic research

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Eco-Environment & Health 2023年第1期2卷 18-20页

作者： Mohamed helal Nanna B.Hartmann Farhan R.Khan elvis Genbo Xu Department of Biology University of Southern DenmarkOdense5230Denmark Department of Environmental and Resource Engineering Technical University of Denmark2800 Kgs.LyngbyDenmark Norwegian Research Centre(NORCE) Nygårdsporten 112NO-5008BergenNorway

Large-scale production of plastics began in the 1950s followed by an onset of exponential growth,leading to its current widespread and dominant *** this,no holistic risk assessment has yet been made on the health and environmental impacts of plastics,their degradation products,or their constituent *** entering the environment,plastics undergo structural,chemical,and functional transformations,leading to the creation of microplastics and nanoplastics[1,2,3].Environmental exposure to microplastics and nanoplastics becomes inevitable,causing direct human dietary exposure.

关键词： plastics integrate spite

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潜水员用伺服控制呼吸调节器的最佳设计

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机电设备 1985年第12期 5-22页

作者： A.Baz s.Kassem H.helal s.Mikhail 陆品英

本文对潜水员用新型伺服控制呼吸调节器的流量和动态特性进行了分析与综合,并对其性能作了评价。本文着重论述这种新型调节器,因为它们在增加潜水深度和潜水持续时间方面具有巨大潜力,能大大地降抵潜水员的呼吸力。这将使潜水员在极端... 详细信息

本文对潜水员用新型伺服控制呼吸调节器的流量和动态特性进行了分析与综合,并对其性能作了评价。本文着重论述这种新型调节器,因为它们在增加潜水深度和潜水持续时间方面具有巨大潜力,能大大地降抵潜水员的呼吸力。这将使潜水员在极端严峻的潜水环境下免除不必要的疲劳,从而提高潜水员的水下工作效率。本研究旨在拟定可供调节器设计人员在选定这类调节器最佳设计参数时采用的合理的设计程序和设计指南。带设计指南是在对伺服控制调节器流量和动态特性进行分析的基础上并根据最佳控制理论的基本原理拟定的为了便于与传统型调节器设计进行定量比较,本研究还提供了评价这类调节器动态特性的实验技术。研究结果突出表明,该类伺服控制调节器作为潜水员水下生命支持系统用的关键部件具有很大的优点和潜力。

关键词：伺服控制动态特性随动控制调节器控制器潜水深度特性曲线赫德曲线最佳设计最优设计阶跃干扰潜水员

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人工耳蜗植入术后面神经管乳突段的放射学评估与面神经刺激征的相关性

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国际医学放射学杂志 2022年第2期 240-241页

作者： I.Burck R.A.helal N.N.N.Naguib N.E.A.Nour-eldin J.E.scholtz s.Martin I 麻足里伟

摘要目的探讨人工耳蜗植入（CI）术后面神经管乳突段的锥形束CT(CBCT)的评估以及其他可能的临床或植入相关因素与术后面神经刺激征（FNs）的相关性。方法 2位经

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Industrial pathways to lithium extraction from seawater:Challenges and perspectives

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Nano Research Energy 2023年第2期2卷 200-202页

作者： Chenyang Dang Ahmed s.helal Liping Zhu Guiyin Xu Meifang Zhu state Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringDonghua UniversityShanghai 201620China Nuclear Materials Authority 3rd SettlementNew Cairo and Housing and Building National Research CenterGizaEgypt

Lithium ion batteries(LIBs)are widely used in electric vehicles and portable electronic devices due to their high energy density,long cycling life,and low cost[1].With the rapid commercialization of LIBs,the growing demand for the lithium source will cause the shortage of lithium supply[2-4].The commercial lithium salts mainly come from the onshore resources(ores and salt lakes)[4].

关键词： lithium cycling portable

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