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Rotation of Biological Cells:Fundamentals and Applications

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Engineering 2022年第3期8卷 110-126页

作者： Tao Tang Yoichiroh Hosokawa Takeshi hayakawa Yo Tanaka Weihua Li Ming Li Yaxiaer Yalikun Division of Materials Science Nara Institute of Science and TechnologyNara 630-0192Japan Institute of Innovation for Future Society Nagoya UniversityAichi 464-8603Japan Department of Precision Mechanics Faculty of Science and EngineeringChuo UniversityTokyo 112-8551Japan Graduate School of Frontier Biosciences Osaka UniversityOsaka 565-0871Japan RIKEN Center for Biosystems Dynamics Research Osaka 565-0871Japan School of Mechanical MaterialsMechatronicand Biomedical EngineeringUniversity of WollongongWollongongNSW 2522Australia School of Engineering Macquarie UniversitySydneyNSW 2109Australia

Cell rotation is one of the most important techniques for cell manipulation in modern bioscience,as it not only permits cell observation from any arbitrary angle,but also simplifies the procedures for analyzing the mechanical properties of cells,characterizing cell physiology,and performing *** approaches have been reported for rotating cells in a wide range of academic and industrial *** them,the most popular are micro-robot-based direct contact manipulation and field-based non-contact methods(e.g.,optical,magnetic,electric,acoustic,and hydrodynamic methods).This review first summarizes the fundamental mechanisms,merits,and demerits of these six main groups of approaches,and then discusses their differences and limitations in *** aim to bridge the gap between each method and illustrate the development progress,current advances,and prospects in the field of cell rotation.

关键词： Cell rotation Cell reorientation Micromanipulation Microfluidics

HIGH CYCLE FATIGUE PROPERTIES OF NICKEL-BASE ALLOY 718

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Acta Metallurgica Sinica(English Letters) 2004年第4期17卷 345-349页

作者： K.Kobayashi K.Yamaguchi M.hayakawa M.Kimura National Institute for Materials Science Tsukuba Ibaraki 305-0047 JapanNational Institute for Materials Science Tsukuba Ibaraki 305-0047 JapanNational Institute for Materials Science Tsukuba Ibaraki 305-0047 JapanNational Institute for Materials Science Tsukuba Ibaraki 305-0047 Japan

The fatigue properties of nickel-base Alloy 718 with fine- and grain-coarse grains were investigated. In the fine-grain alloy, the fatigue strength normalized by the tensile strength was 0.51 at 107 cycles. In contrast, the fatigue strength of the coarse-grain alloy was 0.32 at the same cycles, although the fatigue strengths in the range from 103 to 105 cycles are the same for both alloys. The fracture appearances fatigued at around 106 cycles showed internal fractures originating from the flat facets of austenite grains for both alloys. The difference in fatigue strength at 107 cycles between the fine- and coarse-grain alloys could be explained in terms of the sizes of the facets from which the fractures originated.

关键词： aerospace material fatigue high temperature internal fracture,facet

Ensemble learning framework for landslide susceptibility mapping:Different basic classifier and ensemble strategy

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Geoscience Frontiers 2023年第6期14卷 170-190页

作者： Taorui Zeng Liyang Wu Dario Peduto Thomas Glade Yuichi S.hayakawa Kunlong Yin Institute of Geological Survey China University of GeosciencesWuhan 430074China ENGAGE—Geomorphic Systems and Risk Research Department of Geography and Regional ResearchUniversity of Vienna1010 ViennaAustria Faculty of Engineering China University of GeosciencesWuhanChina Department of Civil Engineering University of Salerno84084 SalernoFiscianoItaly Faculty of Environmental Earth Science Hokkaido UniversityHokkaido 060-0810Japan

The application of ensemble learning models has been continuously improved in recent landslide susceptibility research,but most studies have no unified ensemble ***,few papers have discussed the applicability of the ensemble learning model in landslide susceptibility mapping at the township *** study aims at defining a robust ensemble framework that can become the benchmark method for future research dealing with the comparison of different ensemble *** this purpose,the present work focuses on three different basic classifiers:decision tree(DT),support vector machine(SVM),and multi-layer perceptron neural network model(MLPNN)and two homogeneous ensemble models such as random forest(RF)and extreme gradient boosting(XGBoost).The hierarchical construction of deep ensemble relied on two leading ensemble technologies(i.e.,homogeneous/heterogeneous model ensemble and bagging,boosting,stacking ensemble strategy)to provide a more accurate and effective spatial probability of landslide *** selected study area is Dazhou town,located in the Jurassic red-strata area in the Three Gorges Reservoir Area of China,which is a strategic economic area currently characterized by widespread landslide *** on a long-term field investigation,the inventory counting thirty-three slow-moving landslide polygons was *** results show that the ensemble models do not necessarily perform better;for instance,the Bagging based DT-SVM-MLPNNXGBoost model performed worse than the single XGBoost *** the eleven tested models,the Stacking based RF-XGBoost model,which is a homogeneous model based on bagging,boosting,and stacking ensemble,showed the highest capability of predicting the landslide-affected ***,the factor behaviors of DT,SVM,MLPNN,RF and XGBoost models reflected the characteristics of slow-moving landslides in the Three Gorges reservoir area,wherein unfavorable lithological conditions and intense human engineering activitie

关键词： Three Gorges Reservoir Area Landslide susceptibility mapping Ensemble learning framework Uncertainty research

Sunitinib-induced hyperammonemic encephalopathy in metastatic gastrointestinal stromal tumors:A case report

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World Journal of Clinical Cases 2023年第31期11卷 7629-7634页

作者： Takaoki hayakawa Shinsuke Funakoshi Yasuo Hamamoto Kenro Hirata Takanori Kanai Department of Internal Medicine Division of Gastroenterology and HepatologyKeio University School of MedicineShinjuku-ku 160-8582TokyoJapan Division of Medical Oncology Department of Internal MedicineTokyo Saiseikai Central HospitalMinato-ku 108-0073TokyoJapan Keio Cancer Center Keio University School of MedicineShinjuku-ku 160-8582TokyoJapan Department of Internal Medicine Keio University School of MedicineShinjuku-ku 160-8582TokyoJapan

BACKGROUND Sunitinib,a multi-targeted tyrosine kinase inhibitor(TKI),has been approved for the salvage treatment of gastrointestinal stromal tumors(GIST).Hyperammonemic encephalopathy is a rare but severe complication of sunitinib ***,we present the case of a 66-year-old male with metastatic GIST without underlying liver cirrhosis who developed sunitinib-induced hyperammonemic *** SUMMARY A 66-year-old male with metastatic GIST was admitted because of reduced *** was administered as the first-line systemic *** experienced repeated episodes of peritonitis due to tumor perforation,and surgery was *** disease was confirmed based on increased liver metastasis,and sunitinib was initiated as a salvage ***,23 d after the third course of sunitinib,he presented to the emergency room with an episode of altered consciousness and behavioral *** on the patient clinical history and examination findings,sunitinib-induced encephalopathy was *** was discontinued,and the patient was treated for *** patient had a normal level of consciousness four days later,and the serum ammonia level gradually *** further neurological symptoms were reported in subsequent *** TKI-induced hyperammonemic encephalopathy is potentially *** receiving TKIs experiencing adverse reactions should undergo systemic evaluation and prompt treatment.

关键词： Tyrosine protein kinase inhibitors Sunitinib malate Hyperammonemic encephalopathy Gastrointestinal stromal tumors Case report

Metrology for sub-Rayleigh-length target positioning in~10^(22)W/cm^(2)laser-plasma experiments

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High Power Laser Science and Engineering 2024年第3期12卷 90-105页

作者： E.A.Vishnyakov A.Sagisaka K.Ogura T.Zh.Esirkepov B.Gonzalez-Izquierdo C.D.Armstrong T.A.Pikuz S.A.Pikuz W.Yan T.M.Jeong S.Singh P.Hadjisolomou O.Finke G.M.Grittani M.Nevrkla C.M.Lazzarini A.Velyhan T.hayakawa Y.Fukuda J.K.Koga M.Ishino K.Kondo Y.Miyasaka A.Kon M.Nishikino Y.V.Nosach D.Khikhlukha I.P.Tsygvintsev D.Kumar J.Nejdl D.Margarone P.V.Sasorov S.Weber M.Kando H.Kiriyama Y.Kato G.Korn K.Kondo S.V.Bulanov T.Kawachi A.S.Pirozhkov ELI Beamlines Facility The Extreme Light Infrastructure ERICDolníBrežanyCzech Republic Kansai Institute for Photon Science(KPSI) QSTKyotoJapan Central Laser Facility Rutherford Appleton LaboratorySTFCHarwell OxfordDidcotUK Institute for Open and Transdisciplinary Research Initiatives Osaka UniversityOsakaJapan HB11 Energy Holdings FreshwaterAustralia Key Laboratory for Laser Plasmas(Ministry of Education) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghaiChina Collaborative Innovation Center of IFSA Shanghai Jiao Tong UniversityShanghaiChina Institute of Plasma Physics ASCR PragueCzech Republic FZU-Institute of Physics ASCR PragueCzech Republic Czech Technical University in Prague FNSPEPragueCzech Republic Institute of Laser Engineering Osaka UniversityOsakaJapan Institute of Physics National Academy of Sciences of UkraineKyivUkraine ISTEQ AR YerevanArmenia

Tight focusing with very small f-numbers is necessary to achieve the highest at-focus ***,tight focusing imposes strong demands on precise target positioning in-focus to achieve the highest on-target irradiance We describe several near-infrared,visible,ultraviolet and soft and hard X-ray diagnostics employed in a~10^(22)W/cm^(2)laser±plasma *** used nearly 10 J total energy femtosecond laser pulses focused into an approximately1.3-μm focal spot on 5±20μm thick stainless-steel *** discuss the applicability of these diagnostics to determine the best in-focus target position with approximately 5μm accuracy(i.e.,around half of the short Rayleigh length)and show that several diagnostics(in particular,3ωreflection and on-axis hard X-rays)can ensure this *** demonstrated target positioning within several micrometers from the focus,ensuring over 80%of the ideal peak laser intensity *** approach is relatively fast(it requires 10±20 laser shots)and does not rely on the coincidence of low-power and high-power focal planes.

关键词： laser-plasma interaction precise target positioning spectroscopy ultra-high intensity X-rays

＂New＂ Translations of Japanese Literature： Socio-cultural Impacts on the Japanese Mind

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Journalism and Mass Communication 2015年第12期5卷 640-649页

作者： Atsuko hayakawa Tsuda College Tokyo Japan

In terms of translation theory today, the essential discussions of ＂otherness＂, coupled with the agenda of bilateral approaches to its untranslatability, are much more intense than ever. The stereotypical images of Japan as something quite alien yet enchanting in Japanese literature, in The Tale of Genji for instance, are drastically different from those in modem novels, where the experience of conflicts with the West in the course of modernization could not be ignored. Shusaku Endo＇s Silence for example, paradoxically questions the translatability of Christianity in the historical context of the Japanese mind. By reading some translated texts of Japanese literature, we come to be aware of the essential factors of＂otherness＂ inherent in Japanese culture and language which, in some socio-cultural ways, has had an interesting effect on Japanese minds. With the growing interest in ＂world literature,＂＂otherness＂ and ＂untranslatability＂ illuminated in the translations of Japanese literature offer a new perspective with which we can re-think our sense of history of modernization on the one hand; and re-evaluate the uniqueness of Japanese language on the other. The remarkable influence of translators whose mother tongue is not Japanese, but who have an excellent command of the language, enables a new Japanese culture to emerge. This is evident in the works of Arthur Binard, an American poet and translator, who enthusiastically criticizes the Japanese policy of atomic energy in his translations of the Japanese poems after World War II, and in the very inspiring essays on Japanese by Roger Pulvers, an Australian writer and playwright who won prizes for his translations of Kenji Miyazawa. Along with such new trend of translations of Japanese literature, how it affects the Japanese mind will be discussed.

关键词： translation of Japanese literature Orientalism "otherness" modernization world literature translation studies

Variations in traffic-related polycyclic aromatic hydrocarbons in PM2.5 in Kanazawa, Japan, after the implementation of a new vehicle emission regulation

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Journal of Environmental Sciences 2022年第11期34卷 38-47页

作者： Wanli Xing Lu Yang Hao Zhang Xuan Zhang Yan Wang Pengchu Bai Lulu Zhang Kazuichi hayakawa Seiya Nagao Ning Tang Graduate School of Medical Sciences Kanazawa UniversityKakuma-machiKanazawa 920-1192Japan Institute of Nature and Environmental Technology Kanazawa UniversityKakuma-machiKanazawa 920-1192Japan Institute of Medical Pharmaceutical and Health SciencesKanazawa UniversityKakuma-machiKanazawa 920-1192Japan

A three-year sampling campaign was conducted at a roadside air pollution monitoring station in the urban area of Kanazawa, Japan. Due to a new emission regulation, PAHs levels decreased over the sampling campaign, exhibiting values of 706 ± 413 pg/m^(3) in 2017, 559 ±384 pg/m^(3) in 2018, and 473 ± 234 pg/m^(3) in 2019. In each year, similar seasonal variations in PAHs levels were observed, with higher levels observed in winter and lower levels in summer. Among the PAHs isomer ratios, we observed that the ratio of benzo[b]fluoranthene(BbF) and benzo[k]fluoranthene(BkF), [Bb F]/([BbF] + [BkF]), and the ratio of indeno[1,2,3-cd]pyrene(IDP) and benzo[ghi]perylene(BgPe), [IDP]/([BgPe] + [IDP]), showed stability over the sampling campaign and were less affected by the new emission regulation, seasonal variations, and regional characteristics. When using the combined ratio ranges of 0.66-0.80([Bb F]/[BbF] + [BkF]) and 0.26-0.49([IDP]/[Bg Pe] + [IDP]), traffic emissions were clearly distinguished from other PAHs emission sources. Principal component analysis(PCA) and positive matrix factorization(PMF) were also performed to further analyse the characteristics of traffic-related PAHs. Overall, this study affirmed the effectiveness of the new emission regulation in the reduction of PAHs emissions and provided a combined range for identifying PAHs traffic emission sources.

关键词： Urban air pollution Traffic emission Roadside air pollution monitoring station Source apportionment

The ultra-low-frequency magnetic disturbances associated with earthquakes

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Earthquake Science 2011年第6期24卷 523-534页

作者： Masashi hayakawa Yasuhide Hobara Kenji Ohta Katsumi Hattori Advanced Wireless Communications Research Center The University of Electro-Communications1-5-1 ChofugaokaChofu Tokyo 182-8585Japan Research Station on Seismo Electromagnetics The University of Electro-Communications1-5-1 ChofugaokaChofu Tokyo 182-8585Japan hayakawa Institute of Seismo Electromagnetics Co.Ltd.Incubation Center The University of Electro-Communications Chofu Tokyo182-8585Japan Information Systems Corp. Earthquake Analysis LaboratoryKita-Aoyama 2-14-42-305Minato-ku Tokyo 107-0061Japan Graduate School of Informatics and Engineering The University of Electro-CommunicationsChofu Tokyo 182-8585Japan Department of Electronic Information Chubu University1200 Matsumoto-choKasugai Aichi 487-8501Japan Faculty of Science Chiba University1-33 YayoiInage Chiba 263-8522Japan

The ultra-low-frequency （ULF） electromagnetic emission is recently recognized as one of the most promising candidates for short-term earthquake （EQ） prediction. This paper reviews previous convincing evidence on the presence of ULF emissions before three major EQs. Then, we present further statistical study on the ULF occurrence, our networks of ULF monitoring in different spatial scales in Japan and finally we present several signal processings to identify the seismogenic emissions by showing latest results for recent large EQs.

关键词： seismogenic ULF emission earthquake prediction magnetic sensor signal processing

China’s Outreach in Palestine:The Quandary of“Made in China”

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Asian Journal of Middle Eastern and Islamic Studies 2018年第3期12卷 354-370,I0006页

作者： Oliver hayakawa Institute of Arab and Islamic Studies University of ExeterExeterUK

This article examines China-Palestine trade,with specific reference to the impact of Chinese imports to the West *** draws upon first hand quantitative(two surveys)and qualitative(semi-structured interviews)data collected in the West Bank in 2016 and *** article discusses three ***,a contextual introduction to China-Palestine trade,both before formal ties were established but specifically in the period following the signing of the Protocol on Economic Relations(PER)in 1994 between the State of Israel and the Palestinian Liberation Organization(PLO).Secondly,an exploration of the traders who have enabled this economic exchange,primarily wholesalers in the immediate postPER period to retailers since the early-mid ***,some of the negative repercussions of this trade are analysed,with specific reference to the Palestinian manufacturing *** article recommends that account be taken of the impact which Israel’s formal and informal policies towards Palestine have on Palestinian life,and how this in turn affects Chinese imports and other forms of external trade.

关键词： China Palestine Israel trade economy