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Hepatic pseudolesions caused by alterations in intrahepatic hemodynamics

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World Journal of Gastroenterology 2021年第46期27卷 7894-7908页

作者： satoshi Kobayashi Department of Quantum Medical Technology Kanazawa University Graduate School of Medical SciencesKanazawa 9200942IshikawaJapan

Hepatic pseudolesion may occur in contrast-enhanced computed tomography and magnetic resonance imaging due to the unique haemodynamic characteristics of the *** concept of hepatic arterial buffer response(HABR)has become mainstream for the understanding of the mechanism of the reciprocal effect between hepatic arterial and portal venous *** HABR is thought to be significantly related to the occurrence of the abnormal imaging findings on arterial phase of contrast enhanced images,such as hepatic arterial-portal vein shunt and transient hepatic attenuation difference,which mimic hypervascular tumor and may cause clinical *** inflow to the liver also cause hepatic pseudolesion,and some of the cases may show histopathologic change such as focal hyperplasia,focal fatty liver,and focal sparing of fatty liver,and called *** understand these phenomena might be valuable for interpreting the liver imaging findings.

关键词： Pseudolesion Focal sparing of fatty liver Computed tomography Hepatic blood flow Hepatic hemodynamics Hyperplastic change

Surface roughness and its role in mediating cell adhesion on cobalt-chromium-molybdenum alloys

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Biosurface and Biotribology 2023年第4期9卷 161-168页

作者： satoshi Migita Graduate School of Science and Engineering Yamagata UniversityYonezawaJapan

Co-Cr-Mo ally(CCM)is commonly used for orthopaedic and dental implants due to its excellent mechanical properties and corrosion ***,the influence of surface roughness on cell attachment and proliferation remains *** study aimed to elucidate the impact of surface roughness of CCM on the attachment and proliferation of *** samples with different values of surface rouges were prepared by ***3T3-E1 mouse osteoblasts were used for cell culture *** attachment,morphology,and the expression of actin stress fibres,vinculin,and distri-bution of yes-associated protein were *** results suggest that surface rough-ness does not significantly affect cell attachment and proliferation on CCM,unlike on *** implies that other properties of CCM,such as physicochemical properties,may play a more substantial role in modulating cell *** study provides important insights into the design of CCM implants,suggesting that approaches beyond tuning surface roughness may be necessary to improve biocompatibility and osseointegration.

关键词： biointerface biological reaction biological response biomaterials biomedical application biosurface

Artificially frozen ground and related engineering technology in Japan

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Research in Cold and Arid Regions 2021年第2期13卷 77-86页

作者： satoshi Akagawa Cryosphere Engineering Laboratory TokyoJapan

Since the 1970's, frozen ground has been developing near the Tokyo Bay area around liquefied natural gas(LNG) inground storage tanks. For disaster prevention purposes, the tanks are constructed below the ground surface. Since the temperature of the liquid stored in the tanks is -162℃ the soil surrounding the tanks freezes. Since this frozen ground has existed for almost half a century, we have permafrost near Tokyo. The development of artificial frozen ground may cause frost heaving, resulting in frost heave forces that may cause structural damage of adjacent LNG in-ground storage ***, the demand for frozen ground engineering increased and consequently we now have advanced technology in this area. Fortunately, we use this engineering technology and artificial ground freezing for civil engineering, especially in big and crowded cities like Tokyo. This paper provides a summary of the testing apparatus, test methods, and assessment methods for frost heaving.

关键词： artificial ground freezing frost heave frozen ground engineering

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Genomics, Proteomics & Bioinformatics 2016年第2期14卷 103-112页

作者： Yusei Kobori satoshi Mizuta Graduate School of Science and Technology Hirosaki University

Graphical representation of DNA sequences is one of the most popular techniques for alignment-free sequence comparison. Here, we propose a new method for the feature extraction of DNA sequences represented by binary images, by estimating the similarity between DNA sequences using the frequency histograms of local bitmap patterns of images. Our method shows linear time complexity for the length of DNA sequences, which is practical even when long sequences, such as whole genome sequences, are compared. We tested five distance measures for the estimation of sequence similarities, and found that the histogram intersection and Manhattan distance are the most appropriate ones for phylogenetic analyses.

关键词： Genome sequence Mitochondria Bitmap image Occurrence frequency Distance measure

Redox regulation of fertilisation and the spermatogenic process

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Asian Journal of Andrology 2011年第3期13卷 420-423,511,512页

作者： Junichi Fujii satoshi Tsunoda Department of Biochemistry and Molecular Biology Graduate School of Medical Science Yamagata University Yamagata 990-9585 Japan Respiratory and Cardiovascular Diseases Research Center Research institute for Advanced Molecular Epidemiology Yamagata University Yamagata 990-9585 Japan Global COE Program for Medical Sciences Japan Society for the Promotion of Science Tokyo Japan

Oxidative stress is one of the major causes of male infertility; it damages spermatogenic cells, the spermatogenic process and sperm function. Recent advances in redox biology have revealed the signalling role of reactive oxygen species （ROS） that are generated by cells. While highly reactive oxidants, such as the hydroxyl radical, exert largely deleterious effects, hydrogen peroxide can feasibly serve as a signal mediator because it is moderately reactive and membrane permeable and because it can oxidize only limited numbers of functional groups of biological molecules. The amino acid side chain most sensitive to oxidation is cysteine sulphydryl, which is commonly involved in the catalysis of some enzymes. Although the reactivity of cysteine sulphhydryl is not very high in ordinary proteins, some phosphatases possess a highly reactive sulphydryl group at their catalytic centre and are thereby oxidatively inactivated by transiently elevated hydrogen peroxide levels after extracellular stimuli and under certain environmental conditions. Peroxiredoxins, in turn, show moderate hydrogen peroxide-reducing activity, and their role in the modulation of ROS-mediated signal transduction in ordinary cells, mediated by protecting phosphatases from oxidative inactivation, has attracted much attention. Although knowledge of the signalling role of ROS in the male reproductive system is limited at present, its significance is becoming a focal issue. Here, we present a review of the emerging signalling role of hydrogen peroxide in testes.

关键词： hydrogen peroxide oxidative stress peroxiredoxin signal transduction

DETERMINANT SOLUTIONS OF THE NONAUTONOMOUS DISCRETE TODA EQUATION ASSOCIATED WITH THE DEAUTONOMIZED DISCRETE KP HIERARCHY

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Journal of Systems Science & Complexity 2010年第1期23卷 153-176页

作者： satoshi TSUJIMOTO Department of Applied Mathematics and Physics Graduate School of InformaticsKyoto University

It is shown that the nonautonomous discrete Toda equation and its Backlund transformation can be derived from the reduction of the hierarchy of the discrete KP equation and the discrete two-dimensional Toda equation. Some explicit examples of the determinant solutions of the nonautonomous discrete Toda equation including the Askey-Wilson polynomial are presented. Finally we discuss the relationship between the nonautonomous discrete Toda system and the nonautonomous discrete Lotka- Volterra equation.

关键词： Askey-Wilson polynomial Darboux transformation discrete KP hierarchy nonautonomous discrete Lotka-Volterra equation nonautonomous discrete Toda equation.

Performance Test and Flow Measurement of Contra-Rotating Axial Flow Pump

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Journal of Thermal Science 2007年第1期16卷 7-13页

作者： Akinori Furukawa Toru Shigemitsu satoshi Watanabe Division of Mechanical Engineering Science Kyushu University744 MotookaNishi-kuFukuoka 819-0395JAPAN

An application of contra-rotating rotors has been proposed against a demand for developing higher specific speed axial flow pump. In the present paper, the advantage and disadvantage of using contra-rotating rotors are described in comparison with conventional type of rotor-stator, based on theoretical and experimental investigations. The advantages are as follows：（1） The pump is inherently designed as smaller sized and at lower rotational speed. （2） A stable head-characteristic curve for flow rate with negative slope appears. （3） As the rear rotor rotational speed is varied as independent control of front rotor, the wider range of high performance operation is obtained by rear rotor speed control in addition to front rotor speed control. The disadvantages are as follows：（1） The structure of double shaft system becomes complex. （2） The pump performance is inferior at over flow rate as the rear rotor loading is weakened. （3） The blade rows interaction from rear rotor to front rotor more strongly appears. Then the rear rotor design is a key to achieve higher pump performance. Some methods to overcome these disadvantages will be discussed in more details toward wider usage of contra-rotating axial flow pump in various industrial fields.

关键词： axial flow pump contra-rotating rotors multiphase flow rotational speed control blade rows interaction

Flow Electrification of Insulated Liquid in Metal Pipes

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Chinese Journal of Mechanical Engineering 2012年第6期25卷 1115-1120页

作者： ZHU Shouxin LIU Lin TAKAHASHI satoshi School of Information and Engineering Huzhou Teachers College Huzhou 313000 China Graduate School of Natural Science and Technology Okayama University Okayama Japan

When relative motion occurs between a liquid and a solid, the two phases carry electric charge with opposite signs. The created charge easily accumulates in the liquid, and the amount of the charge carried in an insulated liquid refers to many factors, such as contact area with the solid surface, the contact time, and so forth. However, current theories agree that the amount of charge created during flow electrification is proportional to the contact surface. In this paper, the classical wall current theory is applied to establish an interfacial electrical double-layer model of flow electrification phenomena when an insulated liquid passes over metal pipe surface. Meanwhile, in conjunction with charge relaxation function, the relation between the charge density and flow velocity, the contact time and the contact area is obtained during the liquid flowing process. The experimental result demonstrates that the flowing charge carried in the insulated liquid is not simply proportional to the contact area, but has a non-linear dependence on the contact area and the contact time. Moreover, down flow experimental equipment pipes of different length and diameter, and dielectric hydraulic oil VG46 are used in an experimental study of laminar flow, in order to understand electrification phenomena in dielectric liquid flowing over metal pipes of different length and aperture. If they both increase linearly, charge relaxation will increase exponentially. As a result, the test result verifies related theoretical analysis, and the method given provides a theoretical basis to analyze interracial electrical phenomena.

关键词： flow electrification metal pipes contact time relaxation

High Resolution Clinometers for Measurement of Roll Error Motion of a Precision Linear Slide

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Chinese Journal of Mechanical Engineering 2018年第5期31卷 8-16页

作者： Yuki Shimizu satoshi Kataoka Wei Gao Department of Finemechanics Tohoku University

This paper proposes a new method for measurement of the roll error motion of a slide table in a precision linear slide. The proposed method utilizes a pair of clinometers in the production process of a precision linear slide, where the roll error motion measurement will be carried out repeatedly to confirm whether the surface form errors of slide guideways in the linear slide are su ciently corrected by hand scraping process. In the proposed method, one of the clinometers is mounted on the slide table, while the other is placed on a vibration isolation table, on which the precision linear slide is mounted, so that influences of external disturbances can be cancelled. An experimental setup is built on a vibration isolation table, and some experiments are carried out to verify the feasibility of the proposed method.

关键词： Linear slide Clinometer Rotational error motion measurement