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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第4期25卷 292-310页

作者： Rendi KURNIAWAN Moran XU Min Ki CHOO Shuo CHEN Yein KWAK' Jielin CHEN Saood ALI hanwei teng Pil Wan HAN Gi Soo KIM Tae Jo KO Precision Machining Laboratory Department of Mechanical Engineering Yeungnam UniversityGyeongsansiGyeongbuk-doRepublic of Korea Korea Electrotechnology Research Institute(KERI) ChangwonsiGyeongsangnam-doRepublic of Korea KASWIN Co. LtdChangwon-siGyeongsangnamdoRepublic of Korea

This study presents the development of an ultrasonic transducer with a radius horn for an ultrasonic milling spindle(UMS)*** ultrasonic transducer was intended to have a working frequency of approximately 30 *** different materials were considered in the study:stainless steel(SS 316L)and titanium alloy(Ti-6Al-4V).Titanium alloy gave a higher resonance frequency(33 kHz)than stainless steel(30 kHz)under the same preload compression *** electromechanical impedance simulation was carried out to predict the impedance resonance frequency for both materials,and the effect of the overhanging toolbar was *** to the electromechanical impedance simulation,the overhanging toolbar length affected the resonance frequency,and the error was less than 3%.Harmonic analysis confirmed that the damping ratio helps determine the resonance ***,damping ratios of 0.015-0.020 and 0.005-0.020 were selected for stainless steel and titanium alloy,respectively,with an error of less than 1.5%.Experimental machining was also performed to assess the feasibility of ultrasonic-assisted milling;the result was a lesser cutting force and better surface topography of Al 6061.

关键词： Ultrasonic spindle Ultrasonic vibration assisted-milling(UVAM) 1-degree of freedom(DOF) Frequency Amplitude Milling

Progress,implications,and challenges in using humanized immune system mice in CAR-T therapy-Application evaluation and improvement

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Animal Models and Experimental Medicine 2024年第1期7卷 3-11页

作者： hanwei Yue Lin Bai NHC Key Laboratory of Human Disease Comparative Medicine Institute of Laboratory Animal SciencesCAMS and PUMCChao-yang DistrictBeijingChina

In recent years,humanized immune system(HIS)mice have been gradually used as models for preclinical research in pharmacotherapies and cell therapies with major breakthroughs in tumor and other fields,better mimicking the human immune system and the tumor immune microenvironment,compared to traditional immunodeficient *** better promote the application of HIS mice in preclinical research,we se-lectively summarize the current prevalent and breakthrough research and evaluation of chimeric antigen receptor(CAR)-T cells in various antiviral and antitumor *** exploring its application in preclinical research,we find that it can better reflect the actual clinical patient condition,with the advantages of providing high-efficiency detection indicators,even for progressive research and *** believe that it has better clinical patient simulation and promotion for the updated design of CAR-T cell therapy than directly transplanted immunodeficient *** characteristics of the main models are proposed to improve the use defects of the existing models by reducing the limitation of antihost reaction,combining multiple models,and unifying sources and organoid *** study of relapse and toxicity after CAR-T treatment also provides more possibilities for application and development.

关键词： antitumor antiviral CAR-T humanized immune system model humanized mice preclinical research

Light-emitting devices based on atomically thin MoSe_(2)

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Journal of Semiconductors 2024年第4期45卷 19-35页

作者： Xinyu Zhang Xuewen Zhang hanwei Hu Vanessa Li Zhang Weidong Xiao Guangchao Shi Jingyuan Qiao Nan Huang Ting Yu Jingzhi Shang Institute of Flexible Electronics Northwestern Polytechnical UniversityXi'an 710129China School of Physics and Technology Wuhan UniversityWuhan 430072China Wuhan Institute of Quantum Technology Wuhan 430206China

Atomically thin MoSe_(2) layers,as a core member of the transition metal dichalcogenides(TMDs)family,benefit from their appealing properties,including tunable band gaps,high exciton binding energies,and giant oscillator strengths,thus pro-viding an intriguing platform for optoelectronic applications of light-emitting diodes(LEDs),field-effect transistors(FETs),sin-gle-photon emitters(SPEs),and coherent light sources(CLSs).Moreover,these MoSe_(2) layers can realize strong excitonic emis-sion in the near-infrared wavelengths,which can be combined with the silicon-based integration technologies and further encourage the development of the new generation technologies of on-chip optical interconnection,quantum computing,and quantum information ***,we overview the state-of-the-art applications of light-emitting devices based on two-dimensional MoSe_(2) ***,we introduce recent developments in excitonic emission features from atomically thin MoSe_(2) and their dependences on typical physical ***,we focus on the exciton-polaritons and plasmon-exciton polaritons in MoSe_(2) coupled to the diverse forms of optical ***,we highlight the promising applications of LEDs,SPEs,and CLSs based on MoSe_(2) and their ***,we summarize the challenges and opportunities for high-quality emis-sion of MoSe_(2) and high-performance light-emitting devices.

关键词： MoSe_(2) light-matter interaction exciton polariton light-emitting device

Photoswitchable Molecular Recognition Enabled by Dithienylethene-Mediated Structural Changes of Dynamic Covalent Hydrazone Bonds

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CCS Chemistry 2024年第2期6卷 497-506页

作者： Lifeng Wang Hanxun Zou Hebo Ye Yu Hai hanwei Lu Junmiao Deng Lei You State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002 College of Chemistry and Material Science Fujian Normal UniversityFuzhou 350007 University of Chinese Academy of Sciences Beijing 100049 Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China Fuzhou 350108

Light-induced recognition,assemblies,and materials are intensive areas of research due to their high spatiotemporal ***,we demonstrated photoswitchable molecular recognition via dithienylethene-triggeredreversible structural regulation of dynamic covalent hydrazone *** combining dithienylethenes and cyclic hemiacetals,the photochemical open-ring and closed-ring forms enabled turningoff and on the creation of awide range of hydrazones when ***-induced bidirectional switching between hydrazones and their cyclization structures promoted by a neighboring carboxyl group was further *** taking advantage of reversible structural changes totoggleon andoff the binding pocket,photoswitchable recognitionofmetal ionswas ***,the construction of an acylhydrazone polymer offered a facile way for light-mediated selective extraction/*** strategies and results reported here should find applications in many contexts,such asdynamicassemblies,molecular switches,and smart materials.

关键词： molecular recognition photoswitch dynamic covalent chemistry hydrazone selective extraction/release

AIE gel exhibiting continuous gradient fluorescence based on a polar-responsive AIE-gen

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SmartMat 2024年第2期5卷 83-92页

作者： Ziqing Hu hanwei Zhang Hui Liu Jinsa Li Xiaofan Ji Ben Zhong Tang Key Laboratory of Materials Chemistry for Energy Conversion and Storage Ministry of EducationHubei Key Laboratory of Materials Chemistry and Service FailureHubei Engineering Research Center for Biomaterials and Medical Protective MaterialsSchool of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhanChina School of Science and Engineering Shenzhen Institute of Aggregate Science and TechnologyThe Chinese University of Hong KongShenzhenGuangdongChina

Traditional multicolor fluorescent hydrogels are generated through the assembly of discrete fluorescent hydrogels,which is not a complete integration much distinct from living *** the basis of aggregation-induced emission(AIE),a special solvent polar-responsive AIE molecule possessing a twisted intramolecular charge transfer(TICT)effect was *** incorporating it into the gel network,an AIE gel that displays continuous gradient fluorescence was ***,hydrogel A containing the solvent polar-responsive AIE-gen was prepared to show orange *** soaking in the organic solvents,the fluorescence color transition of hydrogel A ranging from orange to green occurred when being immersed in high-polarity organic solvents ascribed to the embedded AIE-gen owning TICT ***,hydrogel A was successively lifted up from organic *** to the different immersion time of each section for the hydrogel,the polarity difference ***,the produced gel B showed continuous gradient fluorescence ranging from orange to green under the irradiation of UV light.

关键词： aggregation-induced emission fluorescent hydrogel multicolor polar-responsiveness

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异构编队卫星近距离操作轨迹规划方法

明代中后期江南地域意识与书画史书写——基于《吴郡丹青志》的考察

系统工程与电子技术 2024年第3期46卷 1048-1057页

作者：王涵巍张嘉城朱阅訸国防科技大学空天科学学院湖南长沙 410073 空天任务智能规划与仿真湖南省重点实验室湖南长沙 410073

针对编队卫星的空间在轨服务任务,提出一种多类载荷异构星群的协同操作方案.首先,考虑星间自主通信,建立了由一颗主故障识别的观测卫星和多颗主维修补给的操作卫星构成的编队系统.其次,提出一种基于循环交替策略的多星协同轨迹规划方法... 详细信息

针对编队卫星的空间在轨服务任务,提出一种多类载荷异构星群的协同操作方案.首先,考虑星间自主通信,建立了由一颗主故障识别的观测卫星和多颗主维修补给的操作卫星构成的编队系统.其次,提出一种基于循环交替策略的多星协同轨迹规划方法,并基于差分进化算法优化了星群轨迹.最后,结合算例仿真,分析了系统内各成员卫星在编队控制过程中所需的脉冲大小以及编队系统整体的安全性能.仿真结果表明,异构编队系统可快速规划出安全性较高、鲁棒性较强的在轨服务轨迹,具有一定的工程应用价值.

关键词：在轨服务编队飞行近距离操作进化算法

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学术研究 2024年第2期 45-51页

作者：王菡薇同济大学人文学院上海200092

明代中后期江南地区已经形成具有自身特点的书画审美趣味与收藏品味,审美趣味对书画创作风格带来了特定影响。书画鉴藏审美的转变,促进了书画区域审美观的形成。《吴郡丹青志》是一部具有地域性质的画史,内容是对其时江南地区的25位画... 详细信息

明代中后期江南地区已经形成具有自身特点的书画审美趣味与收藏品味,审美趣味对书画创作风格带来了特定影响。书画鉴藏审美的转变,促进了书画区域审美观的形成。《吴郡丹青志》是一部具有地域性质的画史,内容是对其时江南地区的25位画家分别撰写的传记,并进行了品评,不仅是作者王穉登的观点,也是当时江南文人圈书画意识凝聚的结果。

关键词：明代中后期《吴郡丹青志》书画史

外源谷胱甘肽对嫁接黄瓜砧穗种子萌发过程中自毒胁迫的缓解效应

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核农学报 2016年第8期30卷 1633-1638页

作者：于威颉建明滕汉玮甘肃农业大学甘肃兰州730070 兰州市农业技术研究推广中心甘肃兰州730010

为探讨外源谷胱甘肽(GSH)对自毒作用的缓解效果和生理作用机制,以连作嫁接黄瓜根际土壤浸提液模拟自毒胁迫,在100g·L^(-1)浓度土壤浸提液中分别添加0、25、50、100、200 mg·L^(-1)GSH,进行黄瓜、南瓜种子萌发试验,分别测定发芽率、主... 详细信息

为探讨外源谷胱甘肽(GSH)对自毒作用的缓解效果和生理作用机制,以连作嫁接黄瓜根际土壤浸提液模拟自毒胁迫,在100g·L^(-1)浓度土壤浸提液中分别添加0、25、50、100、200 mg·L^(-1)GSH,进行黄瓜、南瓜种子萌发试验,分别测定发芽率、主根长度、根系表面积、根尖数、α-淀粉酶活性、淀粉酶总活性和脯氨酸含量等指标。结果表明,土壤浸提液处理后,黄瓜和南瓜种子的发芽率、发芽指数、活力指数、主根长度、根尖数、根系表面积、α-淀粉酶活性、淀粉酶总活性得到显著抑制,脯氨酸含量升高。在自毒作用下,外施不同浓度GSH,可不同程度地提高种子发芽率、发芽指数、活力指数、主根长度、根系表面积、α-淀粉酶活性、淀粉酶总活性,降低脯氨酸含量。土壤浸提液能对黄瓜、南瓜种子产生自毒作用,添加外源GSH能诱导黄瓜和南瓜种子内淀粉酶活性增强,有效缓解自毒作用对黄瓜、南瓜种子萌发和幼苗生长的抑制作用,并且以100 mg·L^(-1)GSH缓解效果最显著。本研究结果为制定缓解嫁接黄瓜连作障碍措施提供了理论依据。

关键词：谷胱甘肽嫁接黄瓜自毒种子萌发缓解效应

从“理性”到“理由”:社会与情感能力培养的规范性审视

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教育研究 2024年第3期45卷 87-99页

作者：唐汉卫黄忠敬教育部人文社会科学重点研究基地华东师范大学基础教育改革与发展研究所上海200062

在真实社会生活中,社会与情感能力不仅是平衡能力,也有道德上的对错之分。从社会与情感能力培养的角度看,规范性维度不可回避。在规范性问题上,不能再用理性至上的等级化眼光看待理性和情感关系。二者平等交融,共同为规范性奠基。社会... 详细信息

在真实社会生活中,社会与情感能力不仅是平衡能力,也有道德上的对错之分。从社会与情感能力培养的角度看,规范性维度不可回避。在规范性问题上,不能再用理性至上的等级化眼光看待理性和情感关系。二者平等交融,共同为规范性奠基。社会与情感能力中的情感是包含认知因素的“大写的情感”,代表心灵整体的力量,是反思性情感。规范性的确立或者说道德判断形成的过程,就是道德理由的寻获和证成过程。经主体间的情感交流和反思所形成的理由,而不是理性,才是道德判断的根本依据。社会与情感能力培养应注重以情育德的新路。于学校而言,就是要突出情感参与、情感交流和反思、群体共同的情感关切、情感差异和情感治理等在道德理由形成中的作用。即注重情感表达,彰显学校的情感底色;培养自主反思能力,为道德判断提供矫正器;激发公共情感,为公共道德理由提供黏合剂;正视情感差异,为道德进步创造助推器;改进情感治理,为情感交流提供保障机制。

关键词：立德树人社会与情感能力情感治理道德理由

黄土区不同地貌类型耕地土壤养分空间格局及驱动因素

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水土保持研究 2024年第5期31卷 221-231页

作者：贺军奇拜寒伟王金泉徐轶玮倪莉莉长安大学水利与环境学院旱区地下水文与生态效应教育部重点实验室水利部旱区生态水文与水安全重点实验室陕西省科技交流中心陕西省耕地质量与环境保护工作站

[目的]了解黄土区不同地貌条件耕地土壤养分空间格局，揭示养分空间变化的驱动因素，可为区域农业精准管理及农田工程建设提供参考。[方法]基于陕西黄土区2020年耕地土壤养分数据，采用克里金插值揭示4种不同地貌耕地土壤养分空间格局... 详细信息

[目的]了解黄土区不同地貌条件耕地土壤养分空间格局，揭示养分空间变化的驱动因素，可为区域农业精准管理及农田工程建设提供参考。[方法]基于陕西黄土区2020年耕地土壤养分数据，采用克里金插值揭示4种不同地貌耕地土壤养分空间格局，采用地理探测器模型探讨养分空间变化的驱动因素作用。[结果](1)长城沿线风沙滩区、陕北黄土丘陵沟壑区、渭北黄土台塬区和关中平原区有机质(SOM)含量均值分别为10.20,10.08,15.28,18.78 g/kg,全氮(TN)均值分别为0.63,0.66,0.98,1.19 g/kg,有效磷(AP)均值分别为12.99,13.10,16.97,27.24 mg/kg,速效钾(AK)均值分别为117.72,149.94,217.27,252.83 mg/kg,各养分空间格局总体呈现出“风沙滩—丘陵沟壑—台塬—平原”逐渐递增的趋势；(2)日照时长对陕西黄土区整体养分含量解释力最大，其次为年气温与化肥用量，风沙滩区养分分布受土壤容重影响最大，丘陵沟壑区、台塬区及平原区均受化肥用量影响最大，排名前列的因子交互作用对养分的解释力均强于其单因子作用。[结论]风沙滩区及丘陵沟壑区宜适当增加养分输入及提升土壤保肥能力，台塬区及平原区宜注重提高养分利用效率；在农田建设过程中，应根据不同地貌区环境特征因地制宜地进行人为活动。

关键词：土壤养分驱动因素地理探测器地貌类型黄土区

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