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流程工业 2017年第16期 21-23页

作者： Heike Haarmann Daniel gauch Eckhard roos Festo Didactic SE公司 Festo公司

流程工业4．0的排位赛对企业是一个挑战，且是对企业所有层次的挑战。同时，在工业4．0的影响下也出现了一些新的职业和工种，例如工业化的水处理企业就在讨论是否需要像“水电一体化”这样的工种。

关键词：流程工业职业企业一体化水处理工业化工种

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美国ASV装甲安全车

国外坦克 1997年第4期 20-21页

作者： Johng.roos 郭春兰

经过多年研究和装甲车制造厂商间的激烈竞争,美国陆军和空军安全部队即将找到一种能够填补其现役的高机动性多用途轮式车辆和标准的装甲车辆(M113和“布雷德利”)之间长期存在的空白。到1996年底,特克斯特伦海陆系统公司的卡迪拉克·盖... 详细信息

经过多年研究和装甲车制造厂商间的激烈竞争,美国陆军和空军安全部队即将找到一种能够填补其现役的高机动性多用途轮式车辆和标准的装甲车辆(M113和“布雷德利”)之间长期存在的空白。到1996年底,特克斯特伦海陆系统公司的卡迪拉克·盖奇公司,将提供4辆装甲安全车(ASV,也称防暴车)样车给陆军进行试验。为空军研制样车的工作也已列入计划。

关键词：装甲车辆轮式车辆高机动性美国陆军系统公司空军多用途进行试验制造厂商部队

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成功并购的三大要素

商学院 2006年第9期 70-71页

作者： Kees Cools Jeff gell Alexander roos 波士顿咨询公司阿姆斯特丹办公室荷兰groningen大学波士顿咨询公司芝加哥办公室波士顿咨询公司柏林办公室

我们发现那些经常进行并购交易的公司获得的长期股东回报比仅仅依靠自然增长的公司要卓越。尽管最成功的连环收购者的行动看似很疯狂,但他们所应用的方法非常明确而且可以复制。这些公司只对那些期望回报超出资本成本的交易感兴趣,而且... 详细信息

我们发现那些经常进行并购交易的公司获得的长期股东回报比仅仅依靠自然增长的公司要卓越。尽管最成功的连环收购者的行动看似很疯狂,但他们所应用的方法非常明确而且可以复制。这些公司只对那些期望回报超出资本成本的交易感兴趣,而且利用系统的、"行家里手"的方式来对待收购过程。成功实现并购的三个关键要素为:战略重点(增长的领域,不是收购的目标)、纪律严明的价值估值以及提前制定的跨职能整合计划。尽管这些要素看起来都是很明显的必要条件,很多公司往往对此不屑一顾。

关键词：并购中国资本市场凯雷集团三一重工雪津啤酒股东回报人民币比利时

Comparative analysis of DNA extraction protocols for ancient soft tissue museum samples

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Zoological Research 2021年第3期42卷 280-286页

作者： Ming Zhang Peng Cao Qing-Yan Dai Yong-Qiang Wang Xiao-Tian Feng Hong-Ru Wang Hong Wu Albert Min-Shan Ko Xiao-Wei Mao Yi-Chen Liu Li Yu Christian roos Tilo Nadler Wen Xiao E.Andrew Bennett Qiao-Mei Fu Key Laboratory of Vertebrate Evolution and Human Origins Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijing 100044China CAS Center for Excellence in Life and Paleoenvironment Beijing 100044China University of Chinese Academy of Sciences Beijing 100049China Institute of Cultural Relics and Archaeology in Xinjiang UrumqiXinjiang 830011China State Key Laboratory for Conservation and Utilization of Bioresource in Yunnan Yunnan UniversityKunmingYunnan 650091China gene Bank of Primates and Primate genetics Laboratory German Primate CenterLeibniz Institute for Primate ResearchGottingen 37077Germany Wildlife Consultant Cuc Phuong CommuneNho QuanNinh Binh 430000Vietnam Institute of Eastern-Himalaya Biodiversity Research Dali UniversityDaliYunnan 671003China

DNA studies of endangered or extinct species often rely on ancient or degraded *** majority of ancient DNA(aDNA)extraction protocols focus on skeletal elements,with skin and hair samples rarely *** to that found in bones and teeth,DNA extracted from historical or ancient skin and fur samples is also extremely fragmented with low endogenous content due to natural degradation ***,the development of effective DNA extraction methods is required for these ***,we compared the performance of two DNA extraction protocols(commercial and custom laboratory aDNA methods)on hair and skin samples from decades-old museum specimens to Iron Age archaeological *** found that apart from the impact sample-specific taphonomic and handling history has on the quantity and quality of DNA preservation,skin yielded more endogenous DNA than hair of the samples and protocols *** both methods recovered DNA from ancient soft tissue,the laboratory method performed better overall in terms of DNA yield and quality,which was primarily due to the poorer performance of the commercial binding buffer in recovering aDNA.

关键词： endogenous ancient primarily

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从资产剥离中获取最大价值

当代经理人 2007年第12期 114-114,116页

作者： Joe Manget Alexander roos Tawfik Hammoud 波士顿咨询公司多伦多办公室波士顿咨询公司柏林办公室

当你在管理一项资产剥离时,是否只是提供了一些标准的信息模版、粗糙的价值乘数和未来贴现现金流估算?

关键词：最大价值资产剥离贴现现金流管理乘数

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德国媒体的变迁综述

北京印刷学院学报 2015年第5期23卷 1-8页

作者： Alexander W.roos 张志成斯图加特媒体大学斯图加特70569 北京印刷学院北京102600

媒体产业是"创意产业"的重要组成部分。自1990年代以来,由于数字技术的推动,媒体产业正经历着剧烈变迁,如媒介使用的改变,媒体的商业化和新商业模式。从德国的视角对媒体产业变迁进行一个综述。信息和通信技术发展是媒体产业发展的最主... 详细信息

媒体产业是"创意产业"的重要组成部分。自1990年代以来,由于数字技术的推动,媒体产业正经历着剧烈变迁,如媒介使用的改变,媒体的商业化和新商业模式。从德国的视角对媒体产业变迁进行一个综述。信息和通信技术发展是媒体产业发展的最主要驱动力。本文主要对印刷媒体、大众电子媒体和个人媒体的发展进行分析。

关键词：创意产业数字转换媒介使用变迁新商业模式媒体发展

Expression and localization of prostaglandin receptors and stromal factors in human cervix—Variations in pregnant and non-pregnant states

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Open Journal of Molecular and Integrative Physiology 2013年第4期3卷 147-157页

作者： Chellakkan S. Blesson Nathalie roos Olof Stephansson Britt Masironi Susann Reinert Ylva Vladic Stjernholm gunvor Ekman-Ordeberg Lena Sahlin Division for Reproductive Endocrinology and the Pediatric Endocrinology Unit Department of Women’s and Children’s Health Karolinska University Hospital-Solna Karolinska Institutet Stockholm Sweden Division for Reproductive Endocrinology and the Pediatric Endocrinology Unit Department of Women’s and Children’s Health Karolinska University Hospital-Solna Karolinska Institutet Stockholm Sweden Division of Obstetrics and gynecology Department of Women’s and Children’s Health Karolinska University Hospital-Solna Karolinska Institutet Stockholm Sweden Division of Obstetrics and gynecology Department of Women’s and Children’s Health Karolinska University Hospital-Solna Karolinska Institutet Stockholm Sweden Division of Obstetrics and gynecology Department of Women’s and Children’s Health Karolinska University Hospital-Solna Karolinska Institutet Stockholm Sweden Clinical Epidemiology Unit Department of Medicine Karolinska Institutet Stockholm Sweden

Prostaglandins (Pgs) mediate cervical ripening leading to parturition. Pgs are used successfully to induce cervical ripening. However, the cell type specific expression of Pg receptor subtypes and various stromal factors important for cervical ripening in human cervix is not known. Our objective was to investigate the expression and localization of Pg receptors EP1-4 and FP and localization of stromal factors CTgF (connective tissue growth factor), furin, calgranulin ?B, ALOX12 (arachidonate 12-lipooxy-genase) and ALOX15 in human cervical tissue from pregnant and non-pregnant women. Cervical biopsies were obtained from non-pregnant (NP), term pregnant (TP) and post-partum (PP) women. The mRNA expression was determined with real-time PCR, protein expression and localization with immunohistochemistry. Our results show that the EP2 mRNA level was higher in the PP group as compared to TP, whereas the EP4 mRNA level was lower in the TP group as compared to NP. Concomitantly stromal EP2 and epithelial EP3 immunoreactivity was higher in the TP as compared to the NP group, while the EP4 immunostaining in glands was lower in the TP as compared to the PP group. Immunostaining of endothelial CTgF, smooth muscle furin and ALOX12, were all lower in the TP group as compared to NP, for CTgF also the PP group was lower than NP. Endothelial calgranulin B immunoreactivity was higher in the PP group than the NP group. Pg receptors and stromal factors exhibit differential expression in the cervix from women in non-pregnant and pregnant states, implying their involvement in the process of cervical ripening.

关键词： Cervical Ripening Pregnancy Extracellular Matrix Prostaglandin Receptors

Epidemiology of Cancer in Systemic Sclerosis—Systematic Review and Meta-Analysis of Cancer Incidence, Predictors and Mortality

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Open Journal of Rheumatology and Autoimmune Diseases 2013年第4期3卷 231-245页

作者： Tatiana Nevskaya Shelly Chandran Adrienne M. roos Christopher R. Pasarikovski Amie Kron Cathy Chau Sindhu R. Johnson Toronto Scleroderma Program Division of Rheumatology Mount Sinai and Toronto Western Hospitals University of Toronto Toronto Canada Toronto Scleroderma Program Division of Rheumatology Mount Sinai and Toronto Western Hospitals University of Toronto Toronto Canada

Objectives: The study was conducted to improve our understanding of the epidemiology of cancer in systemic sclerosis (SSc) by evaluating the incidence, prevalence, relative risk of overall and site-specific malignancies, predictors and cancer-attributable mortality. Methods: MEDLINE, CINAHL, EMBASE and Cochrane Library (inception-May 2012) were searched. Estimates were combined using a random effects model. Consistency was evaluated using the I2 statistic. Results: 4876 citations were searched to identify 60 articles. The average incidence of malignancy in SSc was 14 cases/1000 person-years;the prevalence ranged between 4%-22%. Cancer was the leading cause of non-SSc related deaths with a mean of 38%. Overall SIR for all-site malignancy risk was 1.85 (95%CI 1.52, 2.25;I276%). There was a greater risk of lung (SIR 4.69, 95%CI 2.84, 7.75;I293%) and haematological (SIR 2.58, CI 95% 1.75, 3.81;I20%) malignancies, including non-Hodgkin’s lymphoma (SIR 2.55, 95%CI 1.40, 4.67;I20%). SSc patients were at a higher risk of leukemia (SIR 2.79, 95%CI 1.22, 6.37;I20%), malignant melanoma (SIR 2.92, 95%CI 1.76, 4.83;I235%), liver (SIR 4.75, 95%CI 3.09, 7.31;I20%), cervical (SIR 2.28, 95%CI 1.26, 4.09;I254%) and oropharyngeal (SIR 5.0, 95%CI 2.18, 11.47;I258%) cancers. Risk factors include a-RNAP I/III seropositivity, male sex, and late onset SSc. Smoking and longstanding interstitial lung disease increase the risk of lung cancer;Barrett’s esophagus and a positive family history of breast cancer, respectively, increase the risk of esophageal adenocarcinoma and breast cancer. Conclusions: SSc patients have a two-fold increase in all-site malignancy, and greater risk of lung and haematological malignancies that contribute significantly to mortality. Vigilance should be considered in SSc patients with risk factors for cancer.

关键词： Systemic Sclerosis Neoplasms Epidemiology Risk Factors Mortality

global view on virus infection in non-human primates and implications for public health and wildlife conservation

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作者： D.·鲁斯(D. roos)

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Zoological Research 2021年第5期42卷 626-632页

作者： Zhi-Jin Liu Xue-Kun Qian Min-Heng Hong Jia-Li Zhang Da-Yong Li Tian-Han Wang Zuo-Min Yang Li-Ye Zhang Zi-Ming Wang Hua-Jian NieKe-Yue Fan Xiong-Fei Zhang Meng-Meng Chen Wei-Lai Sha Christian roos Ming Li College of Life Sciences Capital Normal UniversityBeijing 100048China College of Life Sciences Hebei UniversityBaodingHebei 071002China CAS Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China College of Life Sciences China West Normal UniversityNanchongSichuan 637009China College of Life Sciences Qufu Normal UniversityQufuShandong 273100China Primate genetics Laboratory German Primate CenterLeibniz Institute for Primate ResearchGoettingen 37077Germany State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China gene Bank of Primates German Primate CenterLeibniz Institute for Primate ResearchGoettingen 37077Germany Center for Excellence in Animal Evolution and genetics Chinese Academy of SciencesKunmingYunnan 650223China

Viruses can be transmitted from animals to humans(and vice versa)and across animal *** such,host-virus interactions and transmission have attracted considerable ***-human primates(NHPs),our closest evolutionary relatives,are susceptible to human viruses and certain pathogens are known to circulate between humans and ***,we generated global statistics on virus infections in NHPs(VI-NHPs)based on a literature search and public data *** total,140 NHP species from 12 families are reported to be infected by 186 DNA and RNA virus species,68.8%of which are also found in humans,indicating high potential for crossing species boundaries.

关键词： species. primates attention