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国外畜牧学（猪与禽） 2024年第3期44卷 93-96页

作者：靳文广(译) 范美红(校) 李红(审) 孟祥光(图) hans-wilhelm windhorst 不详

第十五届金砖国家峰会在南非召开,会议决定于2024年1月1日吸纳埃及、阿根廷、埃塞俄比亚、伊朗、沙特阿拉伯和阿拉伯联合酋长国6国为金砖国家的新成员。2021年,金砖国家的鸡肉产量占全球的38.5%,产蛋量占全球的52.0%。

关键词：家禽市场金砖国家市场份额

Tumor-infiltrating lymphocytes in the immunotherapy era

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Cellular & Molecular Immunology 2021年第4期18卷 842-859页

作者： Sterre T.Paijens Annege Vledder Marco de Bruyn hans w.Nijman Department of Obstetrics and Gynecology University of GroningenUniversity Medical Center GroningenGroningenThe Netherlands

The clinical success of cancer immune checkpoint blockade(ICB)has refocused attention on tumor-infiltrating lymphocytes(TILs)across cancer *** outcome of immune checkpoint inhibitor therapy in cancer patients has been linked to the quality and magnitude of T cell,NK cell,and more recently,B cell responses within the tumor ***-of-the-art single-cell analysis of TIL gene expression profiles and clonality has revealed a remarkable degree of cellular heterogeneity and distinct patterns of immune activation and *** of these states are conserved across tumor types,in line with the broad responses observed *** this homology,not all cancer types with similar TIL landscapes respond similarly to immunotherapy,highlighting the complexity of the underlying tumor-immune *** observation is further confounded by the strong prognostic benefit of TILs observed for tumor types that have so far respond poorly to ***,while a holistic view of lymphocyte infiltration and dysfunction on a single-cell level is emerging,the search for response and prognostic biomarkers is just *** this review,we discuss recent advances in the understanding of TIL biology,their prognostic benefit,and their predictive value for therapy.

关键词： Tumor infiltrating lymphocytes B cells T cells Tertiary lymphoid structures immunotherapy

Modern radiological assessment after neoadjuvant therapy in pancreatic cancer: an overview

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胰腺病学杂志(英文) 2024年第3期07卷 207-211页

作者： Steingrüber Marcus Moulla Yousef Denecke Timm Meyer hans-Jonas Department of Diagnostic and Interventional Radiology University of Leipzig Leipzig Germany Department of Visceral Transplant Thoracic and Vascular Surgery University of Leipzig Leipzig Germany

This narrative review provides an overview of the current radiological assessment of pancreatic cancer after neoadjuvant treatment. The current literature was searched for evidence of the different radiological quantitative imaging modalities to stage pancreatic cancer. An overview is given in a narrative method. The quantitative imaging modalities comprise computed tomography (CT) perfusion, dual-energy CT, magnetic resonance imaging, and fluorodeoxyglucose positron emission tomography (FDG-PET)/CT. Radiomics analysis can be used to further characterize the tumors and to reflect the complex tumor microstructure before and after neoadjuvant treatment. Exact extension of the tumor and infiltration of the surrounding tissue is of utter importance to decide, whether the neoadjuvant treatment leads to a resectability or not. There is increasing evidence of the importance of quantitative imaging modalities to assess treatment response in patients with pancreatic cancer after neoadjuvant treatment. Prospective studies employing these modalities are needed to further investigate the benefit for the patients.

关键词： CT FDG-PET/CT MRI Neoadjuvant treatment Pancreatic cancer

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不朽与现代性

世界哲学 2024年第2期 113-126页

作者： [美]H.约纳斯方秋明(译) 林伟毅(译) 不详苏州科技大学政治系福建师范大学马克思主义学院

文章批判了自古以来的两种不朽观,分别为经验性的不朽,包括英名不朽和影响不朽;非经验性的不朽,包括灵魂不朽和实体不朽。这些都被现代性否定了,契合现代性的不朽观是行动不朽,它是自我超越领域的不朽,是指我们存在的某种东西可能通达... 详细信息

文章批判了自古以来的两种不朽观,分别为经验性的不朽,包括英名不朽和影响不朽;非经验性的不朽,包括灵魂不朽和实体不朽。这些都被现代性否定了,契合现代性的不朽观是行动不朽,它是自我超越领域的不朽,是指我们存在的某种东西可能通达了不死性,也就是说我们的世俗行为对超越领域发生影响而产生的不朽。受犹太教中的生命册和诺斯替宗教中上帝的终极形象的启发,文章在这两种象征方式的基础上提出了非全能的上帝形象这个“试验性神话”,认为人类的行为会建构或伤害上帝的形象,只有通过向善的责任行为,维护受到威胁的人类存在,完善上帝的不朽形象,才能获得自身的不朽。

关键词：英名不朽影响不朽灵魂不朽实体不朽行动不朽

CFD based extraction column design-Chances and challenges

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Chinese Journal of Chemical Engineering 2016年第2期24卷 259-263页

作者： Mark w.Hlawitschka Menwer M.Attarakilh Samer S.Alzyod hans-Jorg Bart Chair of Separation Science and Technology POB 3049TU KaiserslauternKaiserslautern 67653Germany Center for Computational and Mathematical Modelling(CM2) TU KaiserslauternKaiserslautern 67653Germany University of Jordan Department of Chemical Engineering11942 AmmanJordan

This paper shows that one-dimensional （I-D） [and three-dimensional （3-D） computational fluid dynamics （CFD）] simulations can replace the state-of-the-art usage of pseudo-homogeneous dispersion or back mixing models. This is based on standardized lab-scale cell experiments for the determination of droplet rise, breakage, coalescence and mass transfer parameters in addition to a limited number of additional mini-plant experiments with original fluids. Alternatively, the hydrodynamic parameters can also be derived using more sophisticated 3- D CFD simulations. Computational 1-D modeling served as a basis to replace pilot-plant experiments in any column geometry. The combination of 3-D CFD simulations with droplet population balance models （DPBM） increased the accuracy of the hydrodynamic simulations and gave information about the local droplet size. The high computational costs can be reduced by open source CFD codes when using a flexible mesh generation. First combined simulations using a three way coupled CFD/DPBM/mass-transfer solver pave the way for a safer design of industrial-sized columns, where no correlations are available.

关键词： CFD DPBM Column design

Chitin synthesis inhibitors： old molecules and new developments

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Insect Science 2013年第2期20卷 121-138页

作者： hans Merzendorfer Department of Biology/Chemistry University of Osnabruck 49069 OsnabrEick Germany

Chitin is the most abundant natural aminopolysaccharide and serves as a structural component of extracellular matrices. It is found in fungal septa, spores, and cell walls, and in arthropod cuticles and peritrophic matrices, squid pens, mollusk shells, nematode egg shells, and some protozoan cyst walls. As prokaryotes, plants and vertebrates including humans do not produce chitin, its synthesis is considered as an attractive target site for fungicides, insecticides, and acaricides. Although no chitin synthesis inhibitor has been developed into a therapeutic drug to treat fungal infections in humans, a larger number of compounds have been successfully launched worldwide to combat arthropod pests in agriculture and forestry. This review summarizes the latest advances on the mode of action of chitin synthesis inhibitors with a special focus on those molecules that act on a postcatalytic step of chitin synthesis.

关键词： acaricide benzoylurea chitin synthesis inhibitor cuticle etoxazole,insecticide

THE GENERALIZED(NONLINEAR)POISSON PROBLEM:A DUAL VARIATIONAL APPROACH

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Acta Mechanica Sinica 1994年第3期10卷 227-236页

作者： hans Bufler Institute for Mechanics Stuttgart UniversityD-70550 StuttgartGermany

A series of problems in mechanics and physics are governed by the ordinary Poisson equation which demands linearity,isotropy,and material homo- *** this paper a generalization with respect to nonlinearity,anisotropy,and inhomogeneity is *** from the canonical basic equations in the primal and dual formulation respectively we derive systematically the corresponding generalized variational principles;under certain conditions they can be extended to so called complementary extremum principles allowing for global *** simplicity a restriction to two dimensional problems is made,including twice-connected domains.

关键词： Generalized Poisson problem dual and complementary variational principles

The Dichotomy Between Traces on d-sets Г in R^n and the Density of D(R^n\Г) in Function Spaces

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Acta Mathematica Sinica,English Series 2008年第4期24卷 539-554页

作者： hans TRIEBEL Mathematisches Institut Fakultt fr Mathematik und InformatikFriedrich-Schiller-Universitt JenaD-07737 JenaGermany

A space Apq^s （R^n） with A ： B or A = F and s ∈R, 0 〈 p, q 〈 ∞ either has a trace in Lp（Г）, where Г is a compact d-set in R^n with 0 〈 d 〈 n, or D（R^n／Г） is dense in it. Related dichotomy numbers are ... 详细信息

A space Apq^s （R^n） with A ： B or A = F and s ∈R, 0 〈 p, q 〈 ∞ either has a trace in Lp（Г）, where Г is a compact d-set in R^n with 0 〈 d 〈 n, or D（R^n／Г） is dense in it. Related dichotomy numbers are introduced and calculated.

关键词： function spaces d-sets fractals traces

DYNAMIC MODEL AND SIMULATION OF THE PLATELETS'ROLE IN BLOOD COAGULATION

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Acta Mechanica Sinica 2002年第4期18卷 420-428页

作者：许传青曾衍钧 hans Grgersen Biomechanics Research Center Beijing Polytechnic Univ.Beijing 100022China Armed Forced InstituteBeijing 100072China Biomechanics Research Center Beijing Polytechnic Univ.Beijing 100022China Center for Sensory-Motor Interaction Aalborg UniversityDenmark

In order to confirm which process is the most important in the blood coagulation cascade,a dynamic model on the function of platelets in blood coagulation is presented based on biochemical *** on qualitative analysis and mathematical simulation,a series of conclusions about the influence of the activation rate of factor VIII and factor IX on the generation of thrombin(IIa)are *** is evident that the pro-coagulation stimulus must exceed a threshold value to initiate the coagulation *** value is related to the binding constant d_2 of the platelet. The stability of the equilibrium value is also related to the pro-coagulation stimulus. This article also evaluates the influence of the stimulus strength and the activated rate parameter of platelets on *** proportion of platelets activated at any given time is designated *** each c,we obtain a maximum concentration of *** is evident that when the level of factor IX is below 1% of the normal level,the rate of thrombin generation reduces dramatically,resulting in severe bleeding tendency.

关键词： dynamic system numerical simulation biochemical process blood coagulation waterfall mechanism

Collaborative Assessments in Computer Science Education: A Survey

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Tsinghua Science and Technology 2019年第4期24卷 435-445页

作者： hans Yuan Paul Cao the Computer Science & Engineering Department University of CaliforniaSan Diego

As computer science enrollments continue to surge, assessments that involve student collaboration may play a more critical role in improving student learning. we provide a review on some of the most commonly adopted collaborative assessments in computer science, including pair programming, collaborative exams, and group projects. Existing research on these assessment formats is categorized and compared. we also discuss potential future research topics on the aforementioned collaborative assessment formats.

关键词： assessment collaboration pair programming collaborative exam group project