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Monitoring the Hydrolysis of Olive Oil Catalyzed by Lipase via Acid Value Detection

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Chemical Research in Chinese Universities 2007年第2期23卷 196-199页

作者： GAO Gui ZHENG Liang-yu ZhanG Zuo-ming han Si-ping CAO Sui-gui Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education Jilin University Changchun 130021 P. R. China

Hydrolysis of olive oil catalyzed by Candida lipolytica lipase was investigated. The relative concentration of the components in the product was determined by using high performance liquid chromatography（HPLC）. Furthermore, a novel rapid method to detect the hydrolytic process of olive oil was developed based on the relationship between the acid value and the relative concentration of the different components.

关键词： Lipase Hydrolysis Olive oil Glyeefide Acid value

Wear fault diagnosis of an emulsion pump crank bearing

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Journal of China University of Mining and Technology 2008年第3期18卷 470-474页

作者： han Xiao-ming DU Chang-long ZhanG Yong-zhong TIE Zhan-xu School of Mechanical and Power Engineering Henan Polytechnic University Jiaozuo Henan 454003 China School of Mechanical and Electronic Engineering China University of Mining ＆ Technology Xuzhou Jiangsu 221008 China

The total load on a crank bearing was calculated by performing a load analysis of the crank connecting rod mechanism. The Reynolds equation for hydrodynamic lubrication of the crank bearing was established at the Reynolds boundary condition and was then solved using the Holland method. From this the regular track of the beating axis was obtained. As the crank beating gradually wears the eccentricity ratio corresponding to the minimum oil film thickness increases gradually. The oil-bound film eventually breaks down, which allows friction and collision between the metal surfaces of the crank pin and the bearing. The rigid impact leads to excitation of high frequency vibrations at the natural frequencies of the connecting rod. The experiments show that the wear condition of the crank beating can be identified correctly through the vibration signature at the natural frequencies of the connecting rod. The degree of wear can be predicted accurately through the energy content of the high frequency bands.

关键词： emulsion pump crank beating wear diagnosis

无失效数据下液体火箭发动机的E-Bayes可靠性分析

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航空学报 2011年第12期32卷 2213-2219页

作者：韩明福建工程学院数理系福建福州350108

为了解决航空航天产品、造价昂贵的产品及高可靠性产品的可靠性评估,本文在无失效数据情况下,对液体火箭发动机进行了可靠性分析。应用E-Bayes(Expected-Bayesian)估计法,在有关研究的基础上,针对液体火箭发动机热试车过程中可能出现的... 详细信息

为了解决航空航天产品、造价昂贵的产品及高可靠性产品的可靠性评估,本文在无失效数据情况下,对液体火箭发动机进行了可靠性分析。应用E-Bayes(Expected-Bayesian)估计法,在有关研究的基础上,针对液体火箭发动机热试车过程中可能出现的无失效数据情况,确定了失效概率的先验分布,并给出了E-Bayes估计和多层Bayes(Bayesian)估计。然后用最小二乘法和加权最小二乘法给出寿命分布的参数估计,进而得到了可靠度的点估计和区间估计。最后结合实际问题进行了计算,说明了方法的可行性,且便于工程应用。

关键词：液体火箭发动机 E-Bayes估计多层Bayes估计可靠性无失效数据最小二乘法区间估计

Should temporary extracorporeal continuous portal diversion replace meso/porta-caval shunts in “small-for-size” syndrome in porcine hepatectomy?

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World Journal of Gastroenterology 2015年第3期21卷 888-896页

作者： Da-Dong Wang Yong Xu Zi-Man Zhu Xiang-Long Tan Yu-Liang Tu ming-ming han Jing-Wang Tan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chinese PLA General Hospital

AIM:To investigate the feasibility of temporary extracorporeal continuous porta-caval diversion(ECPD) to relieve portal hyperperfusion in "small-for-size" syndrome following massive hepatectomy in ***:Fourteen pigs underwent 85%-90% liver resection and were then randomly divided into thecontrol group(n = 7) and diversion group(n = 7).In the diversion group,portal venous blood was aspirated through the portal catheter and into a tube connected to a centrifugal *** filtration,the blood was returned to the pig through a double-lumen catheter inserted into the internal jugular or subclavian *** the conversion pump,portal venous inflow was partially diverted to the inferior vena cava through a catheter inserted via the gastroduodenal vein at 100-130 m L/*** hemodynamics,injury,and regeneration in the liver remnant were compared between the two ***:Compared to the control group,porta-caval diversion via ECPD significantly mitigated excessive portal venous flow and portal vein pressure(PVP); the portal vein flow(PVF),hepatic artery flow(HAF),and PVP in the two groups were not significantly different at baseline; however,the PVF(431.8 ± 36.6 vs 238.8 ± 29.3,P han those in the diversion group,*** HAF in the control group was significantly lower than that in the diversion group at 2 h and 48 h post hepatectomy,and ECPD significantly attenuated injury to the sinusoidal lining and hepatocytes,increased the regeneration index of the liver remnant,and relieved damage that the liver remnant suffered due to endotoxin and bacterial ***:ECPD,which can dynamically modulate portal inflow,can reduce injury to the liver remnant and facilitate liver regeneration,and therefore should replace permanent meso/porta-caval shunts in "smallfor-size" synd

关键词： small-for-size syndrome Extracorporeal continuous

Mechanistic target of rapamycin kinase(Mtor)is required for spermatogonial proliferation and differentiation in mice

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Asian Journal of Andrology 2020年第2期22卷 169-176页

作者： Jun Cao Zuo-Bao Lin ming-han Tong Yong-Lian Zhang Yi-Ping Li Yu-Chuan Zhou State Key Laboratory of Molecular Biology Shanghai Key Laboratory of Molecular AndrologyCAS Center for Excellence in Molecular Cell ScienceShanghai Institute of Biochemistry and Cell BiologyChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 200031China State Key Laboratory of Cell Biology Shanghai Key Laboratory of Molecular AndrologyCAS Center for Excellence in Molecular Cell ScienceShanghai Institute of Biochemistry and Cell BiologyChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 200031China

Spermatogonial development is a vital prerequisite for spermatogenesis and male ***,the exact mechanisms underlying the behavior of spermatogonia,including spermatogonial stem cell(SSC)self-renewal and spermatogonial proliferation and differentiation,are not fully *** studies demonstrated that the mTOR complex 1(mTORC1)signaling pathway plays a crucial role in spermatogonial development,but whether MTOR itself was also involved in any specific process of spermatogonial development remained *** this study,we specifically deleted Mtor in male germ cells of mice using Stra8-Cre and assessed its effect on the function of *** Mtor knockout(KO)mice exhibited an age-dependent perturbation of testicular development and progressively lost germ cells and fertility with *** age-related phenotypes were likely caused by a delayed initiation of Mtor deletion driven by *** examination revealed a reduction of differentiating spermatogonia in Mtor KO mice,suggesting that spermatogonial differentiation was *** proliferation was also impaired in Mtor KO mice,leading to a diminished spermatogonial pool and total germ cell *** results show that MTOR plays a pivotal role in male fertility and is required for spermatogonial proliferation and differentiation.

关键词： male fertility mice Mtor spermatogenesis spermatogonia testis

Hydrogen sutfide protects colon cancer cells from chemopreventative agent β-phenylethyl isothiocvanate induced apoptosis

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World Journal of Gastroenterology 2005年第26期11卷 3990-3997页

作者： Peter Rose Philip K Moore Shen han ming Ong Choon Nam Jeffrey S Armstrong Matt Whiteman Department of Biochemistry National University of Singapore 8 Medical Drive117597Singapore Department of Pharmacology National University of Singapore 18 Medical Drive117597 Singapore Department of Community Occupational and Family Medicine National University of Singapore 16 Medical Drive 117597 Singapore

AIM:Hydrogen sulfide (H2S) is a prominent gaseous constituent of the gastrointestinal (GI) tract with known cytotoxic properties. Endogenous concentrations of H2S are reported to range between 0.2-3.4 mmol/L in the GI tract of mice and humans. Considering such high levels we speculate that, at non-toxic concentrations, H2S may interact with chemical agents and alter the response of colonic epithelium cells to such compounds. The GI tract is a major site for the absorption of phytochemical constituents such as isothiocyanates, flavonoids, and carotenoids, with each group having a role in the prevention of human diseases such as colon cancer. The chemopreventative properties of the phytochemical agent p-phenyethyl isothiocyanate (PEITC) are well recognized. However, little is currently known about the physiological or biochemical factors present in the GI tract that may influence the biological properties of ITCs. The current study was undertaken to determine the effects of H2S on PEITC mediated apoptosis in colon cancer cells. METHODS: Induction of apoptosis by PEITC in human colon cancer HCT116 cells was assessed using classic apoptotic markers namely SubGl population analysis, caspase-3 like activity and nuclear fragmentation and condensation coupled with the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrasodium bromide) viability assay and LDH leakage. RESULTS: PEITC significantly induced apoptosis in HCT116 cells as assessed by SubGl population formation, nuclear condensation, LDH leakage and caspase-3 activity after 24 h, these data being significant from control groups (Phanisms. However, in the presence of H2S, apoptosis was abolished. These data sugg

关键词： Apoptosis Colon cancer Hydrogen sulfide β-phenylethyl isothiocyanate

Study on dynamic response of multi-degree-of-freedom explosion vessel system under impact load

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Defence Technology（防务技术） 2020年第4期16卷 777-786页

作者： Yun-hao Hu Wen-bin Gu Jian-qing Liu Jing-lin Xu Xin Liu Yang-ming han Zhen-xiong Wang College of Field Engineering Army Engineering University of PLANanjing 210007China Unit No.78102 of PLA Chengdu 610031China Unit No.31696 of PLA Jinzhou 121017China Research Institute of Chemical Defense Beijing 102205China

In order to study the dynamic response and calculate the axial dynamic coefficient of the monolayer cylindrical explosion vessel,the wall of vessel is simplified as a multi-degree-of-freedom(MDoF) undamped elastic foundation *** the coupled motion equation and using Duhamel's integrals,the solutions in generalized coordinates of the equations under exponentially decaying loads,square wave loads and triangular wave loads are *** solutions are consistent in form with the solutions of single-degree-of-freedom(SDoF) undamped forced vibration simplified *** on the model,equivalent MDoF design method(also called MDoF dynamic coefficient method) of cylindrical explosion vessel is *** traditional method can only predict the dynamic coefficient of torus portion around the explosion center,but this method can predict that of the vessel wall at any axial n dividing point *** is verified that the prediction accuracy of this model is greatly improved compared with the SDoF model by comparing the results of this model with SDoF model and numerical simulation in different working ***,the prediction accuracy decreases as the scaled distance decreases and approaches the end of the vessel,which is related to the accuracy of the empirical formula of the implosion load,the simplification of the explosion load direction,the boundary conditions,and the loading time difference.

关键词： Explosion vessel Dynamic response Vibration analysis Dynamic coefficient Load feature

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位置-尺度参数模型的可靠性分析

兵工学报 2006年第4期27卷 690-694页

作者：韩明福建工程学院数理系福建福州350014

对位置-尺度参数模型,借助失效概率的E-Bayes估计,给出了位置参数、尺度参数的最小二乘估计和加权最小二乘估计,从而可以得到寿命服从位置-尺度参数模型产品可靠度的估计。最后,结合某型发动机的实际问题进行了计算,结果表明本文提出的... 详细信息

对位置-尺度参数模型,借助失效概率的E-Bayes估计,给出了位置参数、尺度参数的最小二乘估计和加权最小二乘估计,从而可以得到寿命服从位置-尺度参数模型产品可靠度的估计。最后,结合某型发动机的实际问题进行了计算,结果表明本文提出的方法可行且便于应用。

关键词：数理统计学位置-尺度参数模型可靠性最小二乘估计 E—Bayes估计失效概率

可靠性工程中参数的E-Bayes估计法及其应用

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兵工学报 2009年第11期30卷 1473-1476页

作者：韩明福建工程学院数理系福建福州350108

随着科学和技术的进步需要有效地改进工业产品可靠性的评估方法。本文提出了可靠性工程中参数估计的一种方法——E-Bayes估计法。给出了失效概率的E-Bayes估计的定义,在此基础上给出了失效概率的E-Bayes估计和多层Bayes估计,并给出了E-B... 详细信息

随着科学和技术的进步需要有效地改进工业产品可靠性的评估方法。本文提出了可靠性工程中参数估计的一种方法——E-Bayes估计法。给出了失效概率的E-Bayes估计的定义,在此基础上给出了失效概率的E-Bayes估计和多层Bayes估计,并给出了E-Bayes估计的性质——E-Bayes估计和多层Bayes估计的关系。最后,结合实际问题进行了计算,结果表明本文提出的E-Bayes估计法可行且便于工程应用。

关键词：数理统计学可靠性工程失效概率 E-Bayes估计多层Bayes估计