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Journal of Energy Chemistry 2024年第7期94卷 430-440页

作者： Jaewon Baek Sunha Kim hee-Tak Kim Oc hee han Department of Chemical&Biomolecular Engineering KAISTDaejeon 34141Republic of Korea Metropolitan Seoul Center Korea Basic Science InstituteSeoul 03759Republic of Korea Graduate School of Analytical Science&Technology Chungnam National UniversityDaejeon 34134Republic of Korea

Despite the proficiency of lithium(Li)-7 NMR spectroscopy in delineating the physical and chemical states of Li metal electrodes,challenges in specimen preparation and interpretation impede its *** this study,we conducted a comprehensive postmortem analysis utilizing ^(7)Li NMR,employing a stan-dard magic angle spinning probe to examine protective-layer coated Li metal electrodes and LiAg alloy electrodes against bare Li metal electrodes within Li metal batteries(LMBs).Our investigation explores the effects of sample burrs,alignment with the magnetic field,the existence of liquid electrolytes,and precycling on the ^(7)Li NMR *** contrasting NMR spectra before and after cycling,we identi-fied alterations in Li^(0) and Li^(+) signals attributable to the degradation of the Li metal *** NMR analyses decisively demonstrate the efficacy of the protective layer in mitigating dendrite and solid elec-trolyte interphase ***,we noted that Li*ions near the Li metal surface exhibit magnetic susceptibility anisotropy,revealing a novel approach to studying diamagnetic species on Li metal elec-trodes in *** study provides valuable insights and practical guidelines for characterizing distinct lithium states within LMBs.

关键词： NMR spectroscopy Lithium-7 Lithium metal battery Electrolyte Electrode-protective layer Solid electrolyte interface Magnetic susceptibility anisotropy Lithium-metal NMR signal Diamagnetic^(7)Li NMR signal

Selecting suitable sites for mountain ginseng(Panax ginseng)cultivation by using geographically weighted logistic regression

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Journal of Mountain Science 2017年第3期14卷 492-500页

作者： han hee JANG Kwang-min CHUNG Joo-sang Department of Forest Engineering Resources and ManagementCollege of ForestryOregon State UniversityCorvallisOR 97331USA Department of Forest Sciences College of Agriculture and Life SciencesSeoul National UniversitySeoul 08826Republic of Korea Research Institute for Agriculture and Life Sciences Seoul National UniversitySeoul 08826Republic of Korea

With the well-being trends to pursue a healthy life, mountain ginseng(Panax ginseng) is rising as one of the most profitable forest products in South Korea. This study was aimed at evaluating a new methodology for identifying suitable sites for mountain ginseng cultivation in the country. Forest vegetation data were collected from 46 sites and the spatial distribution of all sites was analyzed using GIS data for topographic position, landform, solar radiation, and topographic wetness. The physical and chemical properties of the soil samples, including moisture content, p H, organic matter, total nitrogen, exchangeable cations, available phosphorous, and soil texture, were analyzed. The cultivation suitability at each site was assessed based on the environmental conditions using logistic regression(LR) and geographically weighted logistic regression(GWLR) and the results of both methods were compared. The results show that the areas with northern aspect and higher levels of solar radiation, moisture content, total nitrogen, and sand ratio are more likely to be identified as suitable sites for ginseng cultivation. In contrast to the LR, the spatial modeling with the GWLR results in an increase in the model fitness and indicates that a significant portion of spatialautocorrelation in the data decreases. A higher value of the area under the receiver operating characteristic(ROC) curve presents a better prediction accuracy of site suitability by the GWLR. The geographically weighted coefficient estimates of the model are nonstationary, and reveal that different site suitability is associated with the geographical location of the forest stands. The GWLR increases the accuracy of selecting suitable sites by considering the geographical variations in the characteristics of the cultivation sites.

关键词： Panax ginseng Site suitability Logistic regression Geographically weighted logistic regression Geographic Information System South Korea

Reduced micro RNA 375 in colorectal cancer upregulates metadherin-mediated signaling

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World Journal of Gastroenterology 2019年第44期25卷 6495-6507页

作者： Seol-hee han Ji-Su Mo Won-Cheol Park Soo-Cheon Chae Department of Pathology School of MedicineWonkwang UniversityIksanChonbuk 54538South Korea Digestive Disease Research Institute Wonkwang UniversityIksanChonbuk 54538South Korea

BACKGROUND The human microRNA 375(MIR375)is significantly downregulated in human colorectal cancer(CRC)and we have previously shown that MIR375 is a CRCassociated *** metadherin(MTDH)is a candidate target gene of *** To investigate the interaction and function between MIR375 and MTDH in human *** A luciferase reporter system was used to confirm the effect of MIR375 on MTDH *** expression levels of MIR375 and the target genes were evaluated by quantitative RT-PCR(qRT-PCR),western blotting,or *** MTDH expression was found to be upregulated in human CRC tissues compared to that in healthy *** show that MIR375 regulates the expression of many genes involved in the MTDH-mediated signal transduction pathways[BRAF-MAPK and phosphatidylinositol-4,5-biphosphate-3-kinase catalytic subunit alpha(PIK3CA)-AKT]in CRC *** MTDH expression levels were found to inhibit NF-κB inhibitor alpha,which further upregulated NFKB1 and RELA expression in CRC *** Our findings suggest that suppressing MIR375 expression in CRC regulates cell proliferation and angiogenesis by increasing MTDH ***,MIR375 may be of therapeutic value in treating human CRC.

关键词： MicroRNA 375 Metadherin Mitogen-activated protein kinase Angiogenesis Cell proliferation Colorectal cancer

Incidental accumulation of Technetium-99m pertechnetate in subacute cerebral infarction: A case report

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World Journal of Clinical Cases 2022年第23期10卷 8400-8405页

作者： Yeon-hee han Hwan-Jeong Jeong Hyun Goo Kang Seok Tae Lim Department of Nuclear Medicine Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University HospitalJounbuk National University Medical School and HospitalJeonju 54907JeonbukSouth Korea Department of Neurology Jeonbuk National University Medical School and HospitalJeonju 54907JeonbukSouth Korea

BACKGROUND When interpreting nuclear medicine images,unexpected findings are sometimes *** these findings and determining the mechanism of their occurrence could have a significant impact on early diagnosis of critical diseases and the appropriate management of *** SUMMARY A 59-year-old man was admitted to the emergency room due to left hemiparesis,left hemifacial palsy,and mild *** 2 wk of hospitalization,the patient complained of dry eyes and ***,salivary scintigraphy was performed to evaluate the functional status of his salivary *** accumulation in the right frontoparietal area was found on salivary ***-attenuated inversion recovery phase magnetic resonance(FLAIR phase MR)image showed diffuse high signal intensity in the same *** and posterior horns of the right lateral ventricle were obliterated and the midline was slightly shifted to the left side due to right frontoparietal *** salivary scintigraphy,Tc-99m pertechnetate was incidentally accumulated in a subacute cerebral infarction *** years after the diagnosis of acute infarction,the second series of salivary scintigraphy showed no abnormal activity in the *** phase MR image also demonstrated markedly decreased high signal intensity in the previous infarction lesion without evidence of swelling indicating chronic cerebral *** This case highlights that Tc-99m pertechnetate could accumulate in a subacute cerebral infarction *** mechanism of an unexpected uptake of Tc-99m pertechnetate in unusual sites should be evaluated and kept in mind for better interpretation.

关键词： Cerebral infarction Tc-99m pertechnetate Salivary scintigraphy Case report

ENERGY AND FEASIBILITY ANALYSIS OF APPLYING BIO-BASED PHASE ChanGE MATERIALS TO BUILDINGS IN EAST ASIA

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Journal of Green Building 2020年第2期15卷 157-181页

作者： Abdo Abdullah Ahmed Gassar Geun Young Yun Sumin Kim Choong-hee han The Department of Architectural Engineering Kyung Hee University1732Deogyeong-daeroGiheung-guYongin-si Gyeonggi-do 17104South Korea Department of Architecture and Architectural Engineering Yonsei UniversitySeoul 03722Republic of Korea

The application of phase change materials(PCMs)in building envelopes can help promote energy efficiency due to its high heat *** study aimed to provide energy and economic insights for deploying PCM to buildings in eight different regions of East Asia through a series of energy and economic analysis using computer modelling and *** static payback period(SPP)and dynamic payback(DPP)methods were used to evaluate the economic feasibility of applying a PCM at different melting phase temperatures(20℃,23℃,25℃,27℃ and 29℃).Results show that the proper choice of a PCM melting temperature is a key factor to improve the performance of the PCM applied to buildings.A melting phase temperature of 29℃ achieved the highest economic feasibility in Seoul,Tokyo;Pyongyang;Beijing;and Ulaanbaatar and a melting temperature of 23℃ in Hong Kong had the highest economic ***,the combined economic and energy analysis presented in this study can play an important role in improving the energy and economic feasibility of PCM in buildings.

关键词： BioPCM SPP DPP energy savings office building heating&cooling seasons melting point temperature

Gastric ischemia after epinephrine injection in a patient with liver cirrhosis

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World Journal of Gastroenterology 2013年第3期19卷 411-414页

作者： Su Young Kim Seung-hee han Kyung han Kim Sang Ock Kim Sang-Young han Sung-Wook Lee Yang Hyun Baek Department of Internal Medicine Dong-A University College of MedicineBusan 602-715South Korea

Endoscopic epinephrine injection is relatively easy,quick and ***,it has a low rate of com-plications,and it is widely used for the management of nonvariceal upper gastrointestinal *** have been several case reports of gastric ischemia after en-doscopic injection *** intra-arterial in-jection may result in either spasm or thrombosis,leading to subsequent tissue ischemia or necrosis,although the stomach has a rich vascular supply and the vascular reserve of the intramural *** addition to endoscopic injection therapy,smoking,hypertension and atherosclerosis are risk factors of gastric ischemia. We report a case of gastric ischemia after submucosal epinephrine injection in a 51-year-old woman with hy-pertension and liver cirrhosis.

关键词： Hematemesis Epinephrine Gastric ischemia Liver cirrhosis Hypertension

Lower blood malondialdehyde is associated with past pesticide exposure:findings in Gulf War illness and healthy controls

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Military Medical Research 2022年第2期9卷 205-214页

作者： Beatrice Alexandra Golomb Sridevi Devaraj Alexis K.Messner Hayley Jean Koslik Jun hee han Barnabas Yik Department of Medicine School of MedicineUniversity of CaliforniaSan DiegoLa JollaCA 92093USA Department of Pathology and Immunology Baylor College of MedicineHoustonTX 77030USA Swedish Medical Center SeattleWA 98109USA Henry M.Jackson Foundation for the Advancement of Military Medicine San DiegoCA 92134USA Santa Clara Valley Medical Center San JoseCA 95128USA

Background: Malondialdehyde(MDA) is a candidate general marker of oxidative stress(OS). We sought to assess the relation of MDA to Gulf War illness(GWI) and to a variety of ***: This is an observational study involving subjects from Southern California recruited from October 2011 to May 2014. MDA was assessed in 81 participants(41 GWI-cases, 40 controls). General and Gulf-specific exposures were elicited. MDA case–control comparison was restricted to 40 matched pairs. The potential association between MDA and exposures was assessed using regression analyses. Gulf-specific exposures were incorporated into a case-specific ***: Plasma MDA was significantly lower in GWI-cases than controls. Composite pesticide and fuel-solvent exposures negatively predicted MDA in the total sample, as well as in the analyses that included either GWI-cases or controls only. Self-reported exposure to organophosphate(OP) nerve gas was a strong predictor for lower MDA level in veterans with ***: Past pesticide exposures predicted lower MDA in both veterans with GWI and in healthy controls.

关键词： Malondialdehyde Oxidative stress Free radical Gulf War veterans Gulf War illness Pesticide

Laser-induced plasma generated by a 532nm pulsed laser in bulk water:unexpected line-intensity variation with water temperature and the possible underlying physics

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Plasma Science and Technology 2020年第7期22卷 65-74页

作者： Sandeep KUMARI Jeong PARK Sang-Ho NAM Song_hee han Yonghoon LEE Department of Chemistry Mokpo National UniversityJeonnam 58554Republic of Korea Division of Navigation Science Mokpo National Maritime UniversityJeonnam 58628Republic of Korea

The effect of the matrix temperature on laser-induced plasma generated in bulk water by using a532 nm pulsed laser beam has been *** Ⅰ and Ⅱ emission line intensities were recorded for an aqueous solution of CaCl2 in the temperature range of 7℃-70℃.The emission line intensities did not follow the matrix temperature in our *** intensities were observed at ~18℃ for both ***,a possible mechanism responsible for the observed variation in intensity is suggested,in which laser-produced bubbles play important *** formation is essential to ignite plasma in the liquid and more feasible at the higher liquid ***,the abundant bubbles at the higher temperature can scatter the incident laser beam more effectively to decrease the energy delivered for the laser-induced ***,these two roles have effects on the optical emission intensities in opposite *** validity of the suggested mechanism is discussed based on the plasma temperature,temperature dependence of the refractive index of water,plasma electron density,scattered light intensity,and plasma ignition threshold *** result indicates that the temperature of the liquid is also an important parameter to be considered in the laser-induced breakdown spectroscopy analysis of bulk liquid samples and its application in deep-sea exploration.

关键词： laser-induced breakdown spectroscopy liquid analysis laser-produced bubble

The influence of environmental factors on species composition and distribution in a community forest in Northern Thailand

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Journal of Forestry Research 2021年第2期32卷 649-662页

作者： Siriluck Thammanu Dokrak Marod hee han Narayan Bhusal Lamthai Asanok Pipat Ketdee Noppakoon Gaewsingha Seunghyun Lee Joosang Chung Department of Forest Sciences Seoul National UniversitySeoul 08826Republic of Korea Royal Forest Department Bangkok 10900Thailand Department of Forest Biology Faculty of ForestryKasetsart UniversityBangkok 10900Thailand Department of Forest Policy and Economics National Institute of Forest ScienceSeoul 02455Republic of Korea Department of Agroforestry Maejo UniversityPhrae CampusPhrae 54140Thailand Department of National Parks Wildlife and Plant ConservationBangkok 10900Thailand Research Institute of Agriculture and Life Sciences Seoul National UniversitySeoul 08826Republic of Korea

Understanding the environmental factors that influence tree species composition is essential for successful management of biodiversity and sustainable use of community forest *** study aims to assess tree species composition and distribution in the deciduous Ban Mae Chiang Rai Lum Community Forest in Northern Thailand and to analyze the influence of environmental factors on tree biodiversity in the *** conducted a stratified systematic sampling of the forest’s total area of 3925 ha,and twenty-five 0.16 ha survey plots were established in three different stands of the deciduous forests to estimate and characterize the difference in biological diversity among the *** correspondence analysis(CCA)was used to investigate the environment factors affecting such differences in biodiversity of the *** results showed a high diversity of trees in the forest as 197 species,144 genera,and 62 plant families were *** CCA ordination identified the environmental factors—the most important of which were elevation,distance to streams,soil moisture,organic matter,and distance to communities—that signifi-cantly influenced the diversity and distribution of tree species(p<0.05)in the community *** findings indicate that the implementation of drought reduction measures such as building check dams,fire protection,and monitoring community forest-product usage would be recommended to further biodiversity conservation and the sustainable use of community forest resources.

关键词： Community forest management Species biodiversity Canonical correspondence analysis Ban Mae Chiang Rai Lum community forest Northern Thailand

handheld endomicroscope using a fiber-optic harmonograph enables real-time and in vivo confocal imaging of living cell morphology and capillary perfusion

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Microsystems & Nanoengineering 2020年第1期6卷 449-459页

作者： Kyungmin Hwang Yeong-Hyeon Seo Daniel YKim Jinhyo Ahn Soyoung Lee Kyung hee han Koun-hee Lee Sangyong Jon Pilhan Kim Kate EYu Hyungsin Kim Shin-Hyuk Kang Ki-Hun Jeong Department of Bio and Brain Engineering KAIST and KAIST Institute of Health Science and TechnologyDaejeon 34141Republic of Korea Graduate School of Nanoscience and Technology KAIST and KAIST Institute of Health Science and TechnologyDaejeon 34141Republic of Korea Department of Biological Sciences KAIST and KAIST Institute for the BioCenturyDaejeon 34141Republic of Korea Hyunjoo In-Tech Seoul 08390Republic of Korea VPIX Medical IncDeajeon 34141Republic of Korea Graduate School of Medical Science and Engineering Daejeon 34141Republic of Korea Department of Neurosurgery Korea University Anam HospitalKorea University MedicineSeoul 02842Korea

Confocal laser endomicroscopy provides high potential for noninvasive and in vivo optical biopsy at the cellular ***,we report a fully packaged handheld confocal endomicroscopic system for real-time,high-resolution,and in vivo cellular imaging using a Lissajous scanning fiber-optic *** endomicroscopic system features an endomicroscopic probe with a fiber-optic harmonograph,a confocal microscope unit,and an image signal *** fiber-optic harmonograph contains a single mode fiber coupled with a quadrupole piezoelectric tube,which resonantly scans both axes at~1 kHz to obtain a Lissajous *** fiber-optic harmonograph was fully packaged into an endomicroscopic probe with an objective *** endomicroscopic probe was hygienically packaged for waterproofing and disinfection of medical instruments within a 2.6-mm outer diameter stainless tube capable of being inserted through the working channel of a clinical *** probe was further combined with the confocal microscope unit for indocyanine green imaging and the image signal processor for high frame rate and high density Lissajous *** signal processing unit delivers driving signals for probe actuation and reconstructs confocal images using the auto phase matching process of Lissajous fiber *** confocal endomicroscopic system was used to successfully obtain human in vitro fluorescent images and real-time ex vivo and in vivo fluorescent images of the living cell morphology and capillary perfusion inside a single mouse.

关键词： fiber processor confocal