检索结果-南通市图书馆

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

新时代高校美育的目标定位及实践策略

黑龙江高教研究 2025年第2期43卷 23-28页

作者：韩伟黑龙江大学黑龙江哈尔滨150080

新时代高校美育担负着重要的历史使命,其对全民审美素养的提升具有引领作用。高校美育除了具备审美教育的一般特性,还具有道德涵养属性,其目标在于道德养成。相较于社会美育和中小学美育,高校美育的示范性、体系性、可持续性更强,其可... 详细信息

新时代高校美育担负着重要的历史使命,其对全民审美素养的提升具有引领作用。高校美育除了具备审美教育的一般特性,还具有道德涵养属性,其目标在于道德养成。相较于社会美育和中小学美育,高校美育的示范性、体系性、可持续性更强,其可以扭转当代教育“感性缺失”状况,这构成了高校美育道德养成的人性保障。在高校美育的实施策略上,以“浸润”为总原则,依托公共艺术类课程、中华优秀传统文化和诗性思维,培养通识审美、担当情怀以及愉悦追求,为全社会审美素养提升和创新意识养成提供支持。

关键词：新时代高校美育道德感性美育浸润

维普期刊数据库

Improving postoperative outcomes in patients with pancreatic cancer:Inflammatory and nutritional biomarkers

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Oncology 2025年第1期16卷 59-64页

作者： Chun-han Cheng Wen-Rui Hao Tzu-Hurng Cheng Department of Medical Education Linkou Chang Gung Memorial HospitalTaoyuan 33305Taiwan Division of Cardiology Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei 23561Taiwan Division of Cardiology Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002Taiwan Department of Biochemistry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404328Taiwan

This editorial assesses the prognostic value of preoperative inflammatory and nutritional biomarkers in patients undergoing surgical resection for pancreatic *** et al evaluated the ability of seven biomarkers to predict postoperative recovery and long-term *** biomarkers were albumin-to-globulin ratio,prognostic nutritional index(PNI),systemic immune-inflammation index,neutrophil-to-lymphocyte ratio,platelet-to-lymphocyte ratio,nutritional risk index,and geriatric nutritional risk *** PNI was found to be a strong predictor of both overall and recurrence-free survival,underscoring its clinical relevance in managing patients with pancreatic cancer.

关键词： Pancreatic cancer Prognostic nutritional index Systemic immune-inflammation index Postoperative recovery Prognosis

Insights from untargeted metabolomics: revealing potential marker compounds into the maturation of fermented chili

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2025年

作者： Shiyu Liu Mingyuan Yang Jianhua Zhao Meijuan Lei Jinlin han Min Xu Ping Liu Jie Tang Hongbin Lin School of Food and Bio-engineering， Xihua University China Agricultural University-Sichuan Advanced Agricultural & Industrial Institute Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing Food Microbiology Key Laboratory of Sichuan Province

Chili fermentation is one of the most important processes in the production of Pixian Douban (PXDB)， which determines the flavor and product quality of PXDB. However， the maturity of fermented chili mainly depends on empirical judgment， which can not satisfy the need for standardized production of PXDB. Therefore， this study aimed to investigate volatile and non-volatile substances during the maturation process and to find markers related to the maturity of fermented chili. GC×GC-MS combined with multivariate statistical analysis revealed that 2-methoxy-3-isobutyl pyrazine， linalool， 3-(methylthio)propionaldehyde， myrcene， and decanal (ROAV ≥ 1， VIP > 1， P < 0.05) were regarded as potentially active aromatic markers for differentiating fermentation time. Additionally， UPLC-QTOF-MS combined with multivariate statistical analysis resulted that 14 compounds can serve as differentiated non-volatile compounds. The correlation of maturity-related physico-chemical indicators with volatile and non-volatile compounds revealed that three volatile compounds (2-methoxy-3-isobutylpyrazine， linalool， and decanal) along with fructose and adenosine could serve as markers for evaluating the maturity of chili. This study is expected to establish a standard for the determination of maturity the fermented chili and lay the foundation for intelligent production of PXDB.

关键词：

Impacts of Nutlin-3a and exercise on murine double minute 2-enriched glioma treatment

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1135-1152页

作者： Yisheng Chen Zhongcheng Fan Zhiwen Luo Xueran Kang Renwen Wan Fangqi Li Weiwei Lin Zhihua han Beijie Qi Jinrong Lin Yaying Sun Jiebin Huang Yuzhen Xu Shiyi Chen Department of Sport Medicine Huashan HospitalFudan UniversityShanghaiChina Department of Orthopedic Surgery Hainan Province Clinical Medical CenterHaikou Affiliated Hospital of Central South University Xiangya School of MedicineHaikouHainan ProvinceChina Department of Basic Medicine Shanghai Jiao Tong University School of MedicineShanghai Jiao Tong UniversityShanghaiChina Department of Neurosurgery Second Affiliated Hospital of Zhejiang University School of MedicineZhejiang UniversityHangzhouZhejiang ProvinceChina Department of Orthopedics Shanghai General HospitalSchool of Medicine Shanghai Jiao Tong UniversityShanghaiChina Department of Infectious Diseases Children’s Hospital of Fudan UniversityNational Children’s Medical CenterShanghaiChina Department of Rehabilitation The Second Affiliated Hospital of Shandong First Medical UniversityTaianShandong ProvinceChina

Recent research has demonstrated the impact of physical activity on the prognosis of glioma patients,with evidence suggesting exercise may reduce mortality risks and aid neural *** role of the small ubiquitin-like modifier(SUMO)protein,especially post-exercise,in cancer progression,is gaining attention,as are the potential anti-cancer effects of *** used machine learning to create the exercise and SUMO-related gene signature(ESLRS).This signature shows how physical activity might help improve the outlook for low-grade glioma and other *** demonstrated the prognostic and immunotherapeutic significance of ESLRS markers,specifically highlighting how murine double minute 2(MDM2),a component of the ESLRS,can be targeted by *** underscores the intricate relationship between natural compounds such as nutlin-3 and immune *** comprehensive CRISPR screening,we validated the effects of specific ESLRS genes on low-grade glioma *** also revealed insights into the effectiveness of Nutlin-3a as a potent MDM2 inhibitor through molecular docking and dynamic ***-3a inhibited glioma cell proliferation and activated the p53 *** efficacy decreased with MDM2 overexpression,and this was reversed by Nutlin-3a or *** using a low-grade glioma mouse model highlighted the effect of physical activity on oxidative stress and molecular pathway ***,both physical exercise and Nutlin-3a administration improved physical function in mice bearing tumors derived from MDM2-overexpressing *** results suggest the potential for Nutlin-3a,an MDM2 inhibitor,with physical exercise as a therapeutic approach for glioma *** research also supports the use of natural products for therapy and sheds light on the interaction of exercise,natural products,and immune regulation in cancer treatment.

关键词： exercise and SUMO-related gene signatures(ESLRS) glioblastoma management low-grade glioma natural bioactives neural regeneration physical exercise

维普期刊数据库

Radiomics and molecular analysis:Bridging the gap for predicting hepatocellular carcinoma prognosis

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2025年第4期13卷 56-60页

作者： Chun-han Cheng Wen-Rui Hao Tzu-Hurng Cheng Department of Medical Education Linkou Chang Gung Memorial HospitalTaoyuan 33305TaiwanChina Division of Cardiology Department of Internal MedicineShuang Ho HospitalMinistry of Health and WelfareTaipei Medical UniversityNew Taipei 23561TaiwanChina Division of Cardiology Department of Internal MedicineSchool of MedicineCollege of MedicineTaipei Medical UniversityTaipei 11002TaiwanChina Department of Biochemistry School of MedicineCollege of MedicineChina Medical UniversityTaichung 404333TaiwanChina

This editorial examines a recent study that used radiomics based on computed tomography(CT)to predict the expression of the fibroblast-related gene enhancer of zeste homolog 2(EZH2)and its correlation with the survival of patients with hepatocellular carcinoma(HCC).By integrating radiomics with molecular analysis,the study presented a strategy for accurately predicting the expression of EZH2 from CT *** findings demonstrated a strong link between the radiomics model,EZH2 expression,and patient *** noninvasive approach provides valuable insights into the therapeutic management of HCC.

关键词： Hepatocellular carcinoma Computed tomography Radiomics Enhancer of zeste homologue 2 expression Non-invasive imaging

Dynamic performance enhancement in Ti/Au ohmic contacts on β-Ga2O3-on-Si C substrates: evidence from pulsed measurements

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2025年第1期68卷 400-401页

作者： Chenyu LIU Yibo WANG Wenhui XU Shuqi HUANG Chunxiao YU Zeyu YANG Xiaole JIA Xiaoxi LI Bochang LI Zhengdong LUO Cizhe FANG Yan LIU Tiangui YOU Xin OU Genquan han School of Microelectronics Xidian University Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences hangzhou Institute of Technology Xidian University

Titanium/Gold （Ti/Au） metals have been widely employed as ohmic metal contacts on n+Ga2O3,exhibiting the specific contact resistance （ρc） of 10-5-10-6Ω·cm2[1].But previous studies have revealed the presence of a defective Ga2O3layer and reactive Ti-Ga2O3layer at the annealed Ti/*** an interfacial layer can afect the performance of ohmic contact,which may become more pronounced in power devices subjected to electrical stress and high-frequency ***,there have been no reports on the impact of bias stress effects and dynamic degradation of Ti/Au ohmic contacts on n+Ga2O3.

关键词：

同方期刊数据库

Imidazolium-based ionic polymers for fast and efficient anion-exchange driven capture of Cr2O72-

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年

作者： Yishou Wang Xiaonan Yuan Xingxing Gou Xiatian Song Xiaogang Wang Ling Guo Yanfeng Liu Chengfang Qiao Chunsheng Zhou Yingfeng han Shaanxi Key Laboratory of Comprehensive Utilization of Tailings Resources Shaanxi Engineering Research Center for Mineral Resources Clean & Efficient Conversion and New Materials College of Chemical Engineering and Modern Materials Shangluo University Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education Xi'an Key Laboratory of Functional Supramolecular Structure and Materials College of Chemistry and Materials Science Northwest University

The pervasive issue of chromium（VI） contamination,particularly in dichromate (Cr2O2-7),resulting from unchecked industrial growth and inadequate waste management,remains a pressing concern that demands immediate and dedicated ***,we present two novel imidazolium-based ionic polymers （ImIPs）.The ImIPs boast a highly cationic structure rich in bromide（Br-） ions and exhibit remarkable porosity,facilitating the easy exchange of these ions for chromate (Cr2O2-7) through anion *** unique combination leads to exceptional performance,including a high adsorption capacity （423 mg/g）,rapid adsorption rate (75 mg g-1min-1),and a broad operational pH range （2–12）.Moreover,our material demonstrates remarkable reusability,maintaining its efficacy even after 10 cycles without significant loss of *** mechanistic studies underscore the role of ion-exchange chemistry in effectively removing dichromate by the presented ImIPs,providing strong evidence for their suitability as a robust solution to address the ongoing challenges in water *** findings represent a crucial step in developing advanced materials for tackling chromium（VI） pollution.

关键词：

Weak feedback self-mixing interference fringe slope discrimination method based on deep learning

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Optoelectronics Letters 2025年

作者： ZHAO Yan LIN Maohua DU Shengzhi TONG Jigang LIU Bin han Fangfang School of Electrical Engineering and Automation， Tianjin University of Technology Tianjin Key Laboratory for Control Theory and Applications in Complicated Systems Department of Electrical Engineering， Tshwane University of Technology

In order to identify the tilt direction of the self-mixing interference (SMI) signals under weak feedback regime interfered by noise， a deep learning method is proposed. The one-dimensional U-Net (1D U-Net) neural network can discriminate the direction of self-mixing fringes accurately and quickly. For experimental SMI signals， the 1D U-Net can be used for discriminant direction after a one-step normalization. Simulation and experimental results show that the proposed method is suitable for SMI signals with noise within the whole weak feedback regime， and can maintain a high discrimination accuracy for signals interfered by 5dB noise. Combined with fringe counting method， accurate and rapid SMI signal displacement reconstruction can be realized.

关键词：

知识生产模式转型视域下国家卓越工程师学院创建的动因、机制与进路

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

黑龙江高教研究 2025年第1期43卷 1-8页

作者：刘涵滨天津大学天津300000

国家卓越工程师学院是知识生产模式转型趋势下大学组织变革的时代产物。“科技自立自强”的迫切需求与“回归工程范式”的变革趋势相交叠,构成我国大学创建国家卓越工程师学院的时代动因。探其机制,国家卓越工程师学院形成以服务应用为... 详细信息

国家卓越工程师学院是知识生产模式转型趋势下大学组织变革的时代产物。“科技自立自强”的迫切需求与“回归工程范式”的变革趋势相交叠,构成我国大学创建国家卓越工程师学院的时代动因。探其机制,国家卓越工程师学院形成以服务应用为导向的组织理念、多元主体异质共在的成员构成、持续适应的柔性组织架构、多维综合的质量控制机制。以知识生产模式转型趋势为参照,未来,国家卓越工程师学院应持守育人价值本位,形塑主动适应的组织理念;优化创新制度环境,赋能组织成员的知识协同;提升卓越项目的治理能力,着力构建水样组织;引入公众参与的评价机制,加强知识生产的社会问责。

关键词：知识生产模式转型国家卓越工程师学院组织变革交叉学科组织