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Role of intelligent/interactive qualitative and quantitative analysisthree-dimensional estimated model in donor-recipient size mismatch following deceased donor liver transplantation

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World Journal of Gastroenterology 2023年第44期29卷 5894-5906页

作者： han ding Zhi-Guo ding Wen-Jing Xiao Xu-Nan Mao Qi Wang Yi-Chi Zhang Hao Cai Wei Gong Department of Transplantation Xinhua HospitalAffiliated to Shanghai Jiaotong University School of MedicineShanghai 200092China Department of General Surgery The Third People’s Hospital of YangzhouYangzhou 225126Jiangsu ProvinceChina Department of Tuberculosis Control Shanghai Municipal Center for Disease Control and PreventionShanghai 200336China Department of Biliary-Pancreatic Surgery Shanghai Changzheng HospitalSecond Military Medical UniversityShanghai 200003China Department of Pathology First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029JiangsuChina Department of General Surgery Xinhua HospitalAffiliated to Shanghai Jiaotong University School of MedicineShanghai 200092China Shanghai Key Laboratory of Biliary Tract Disease Research Shanghai200092China

BACKGROUND Donor-recipient size mismatch(DRSM)is considered a crucial factor for poor outcomes in liver transplantation(LT)because of complications,such as massive intraoperative blood loss(IBL)and early allograft dysfunction(EAD).Liver volumetry is performed routinely in living donor LT,but rarely in deceased donor LT(DDLT),which amplifies the adverse effects of DRSM in *** to the various shortcomings of traditional manual liver volumetry and formula methods,a feasible model based on intelligent/interactive qualitative and quantitative analysis-three-dimensional(IQQA-3D)for estimating the degree of DRSM is *** To identify benefits of IQQA-3D liver volumetry in DDLT and establish an estimation model to guide perioperative *** We retrospectively determined the accuracy of IQQA-3D liver volumetry for standard total liver volume(TLV)(sTLV)and established an estimation TLV(eTLV)index(eTLVi)*** operating characteristic(ROC)curves were drawn to detect the optimal cut-off values for predicting massive IBL and EAD in DDLT using donor sTLV to recipient sTLV(called sTLVi).The factors influencing the occurrence of massive IBL and EAD were explored through logistic regression ***,the eTLVi model was compared with the sTLVi model through the ROC curve for *** A total of 133 patients were included in the *** Changzheng formula was accurate for calculating donor sTLV(P=0.083)but not for recipient sTLV(P=0.036).Recipient eTLV calculated using IQQA-3D highly matched with recipient sTLV(P=0.221).Alcoholic liver disease,gastrointestinal bleeding,and sTLVi>1.24 were independent risk factors for massive IBL,and drug-induced liver failure was an independent protective factor for massive *** donor-female recipient combination,model for end-stage liver disease score,sTLVi≤0.85,and sTLVi≥1.32 were independent risk factors for EAD,and viral hepatitis was an independent protective factor for *** overall surv

关键词： Intelligent/interactive qualitative and quantitative analysis-three-dimensional Donor-recipient size mismatch Intraoperative blood loss Early allograft dysfunction

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Friction compensation design based on state observer and adaptive law for high-accuracy positioning system

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Progress in Natural Science:Materials International 2006年第2期16卷 147-152页

作者： WANG Ying, XIONG Zhenhua and ding han (School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China) [a]School of Mechanical Engineering Shanghai Jiao Tong University Shangai China

Friction is one of the main factors that affect the positioning accuracy of motion system. Friction compensation based on friction model is usually adopted to eliminate the nonlinear effect of friction. This paper presents a proportional-plus-derivative (PD) feedback controller with a friction compensator based on LuGre friction model. We also design a state observer to observe the unknown state of LuGre friction model, and adopt a parameter adaptive law and off-line approximation to estimate the parameters of LuGre friction model. Comparative experiments are carried out among our proposed controller, PD controller with friction compensation based on classical friction model, and PD controller without friction compensation. Experimental results demonstrate that our proposed controller can achieve better performance, especially higher positioning accuracy.

关键词： friction compensation state observer adaptive law linear motor motion control.

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Protective effects of riboflavin-UVA-mediated posterior sclera collagen cross-linking in a guinea pig model of form-deprived myopia

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International Journal of Ophthalmology(English edition) 2021年第3期14卷 333-340页

作者： ding han Mei-Nan He Ying Zhu Yan Zhang Rui-Hua Wei Tianjin Key Laboratory of Retinal Functions and Diseases Eye Institute and School of OptometryTianjin Medical University Eye HospitalTianjin 300384China

AIM:To evaluate the effect of posterior sclera collagen cross-linking induced by riboflavin-ultraviolet A(UVA)on form-deprived myopia in guinea ***:Twenty-five pigmented guinea pigs of 3-week-old were randomly assigned into 4 groups that included normal control(NOR,n=7),form-deprived(FDM,n=7),normal with riboflavin-UVA cross-linking(NOR+CL,n=5)and form-deprived with cross-linking(FDM+CL,n=6).The NOR+CL group and the FDM+CL group received the riboflavin-UVA induced cross-linking at day *** was induced by monocularly deprived with facemask in the right *** refraction,axial length and corneal curvature were measured by retinoscopy,A-scan and keratometer respectively in scheduled time points(day 0 and 1,2,3,4 wk after form-deprivation).At the end of 4 weeks’experiment,stress-strain tests of sclera were measured and morphological changes of sclera and retina were ***:After 4 wk,the interocular difference of refractive error were-0.11±0.67,-2.93±0.56,1.10±0.58,and-1.63±0.41 D in the NOR,FDM,NOR+CL,and FDM+CL groups ***-effect linear model revealed significant effect of FDM(Phanical strength in the guinea pig model of form-deprived myopia.

关键词： riboflavin-UVA sclera collagen crosslinking biomechanical strength form-deprived myopia guinea pig

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A data-driven rolling optimization method for trajectory tracking error prediction of CNC machine tools

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Science China Technological Sciences 2024年

作者： Yinxin GUAN Jixiang YANG Shizhong TAN han ding School of Mechanical Science and Engineering State Key Laboratory of Intelligent Manufacturing Equipment and Technology Huazhong University of Science and Technology

The dynamic performance of the feed-drive system in CNC machine tools directly influences the accuracy of machined parts. To enhance the motion control performance of CNC machine tools, a high-precision model of the feed-drive system is critical. However, current modeling methods for feed-drive systems seldom consider time-varying factors such as loads, wear, and lubrication. As a result, the model accuracy degrades when the system characteristics are affected by these time-varying factors. In this paper, a rolling optimization method with partial weights frozen is developed to realize quick iterative learning of a data-driven model for a feed drive system with time-varying characteristics using a small amount of ***, the long short-term memory fully connected (LSTM-FC) network is built and divided into feature extraction and output fitting parts based on their functions. Then, a weight freezing-based rolling optimization method is applied. The weights in the feature extraction part are frozen, which preserves the learned common knowledge and patterns by solidifying the way that high-dimensional features are extracted from the input. By adjusting the weights in the output fitting part, the extracted highdimensional features are remapped to the new data distribution changed by time-varying factors. Finally, the performance of the developed rolling optimization method is confirmed by experiments. The results show that the proposed rolling optimization method reduces the maximum prediction errors by 49.5%and the total training time by 96.3%compared with existing methods,which demonstrates that the proposed method can restore model accuracy when the system characteristics change due to timevarying factors, and significantly accelerate the optimization process by rolling optimization.

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Seasonal variations of organic carbon and nitrogen in the upper basins of Yangtze and Yellow Rivers

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Journal of Mountain Science 2017年第8期14卷 1577-1590页

作者： LI Xiang-ying ding Yong-jian han Tian-ding XU Jian-zhong KANG Shi-chang WU Qing-bai Mika Sillanp?? YU Zhong-bo YU Cong-rong College of Hydrology and Water Resources/State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering Hohai University State Key Laboratory of Cryospheric Sciences Northwest Institute of Eco-Environment and ResourcesChinese Academy of Sciences University of Chinese Academy of Sciences State Key Laboratory of Frozen Soil Engineering Northwest Institute of Eco-Environment and ResourcesChinese Academy of Sciences Laboratory of Green Chemistry School of Engineering ScienceLappeenranta University of Technology Department of Civil and Environmental Engineering Florida International University

The profound impacts exerted by climate warming on the Tibetan Plateau have been documented extensively, but the biogeochemical responses remain poorly understood. This study was aimed at seasonal variations of total organic carbon(TOC) and total organic nitrogen(TON) in stream water at two gauging sections(TTH, ZMD) in the upper basin of Yangtze River(UBYA) and at fourgauging sections(HHY, JM, JG, TNH) in the upper basin of Yellow River(UBYE) in 2013. Results showed that concentrations of TON exhibit higher values in spring and winter and lower values in summer. TOC exhibits higher concentrations in spring or early summer and lower concentrations in autumn or winter. Seasonal variations of TOC and TON fluxes are dominated by water flux. In total, the UBYE and UBYA delivers 55,435 tons C of organic carbon and 9,872 tons N of organic nitrogen to downstream ecosystems in 2013. Although the combined flux ofTOC from UBYA and UBYE is far lower than those from large rivers, their combined yields is higher than, or comparable with, those from some large rivers(e.g. Nile, Orange, Columbia), implying that organic carbon from the Tibetan Plateau may exert a potentially influence on regional and/or global carbon cycles in future warming climate.

关键词： Seasonal variation Total organic carbon(TOC) Total organic nitrogen(TON) Yangtze River Yellow River

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Human umbilical cord mesenchymal stem cell-derived exosomes loaded into a composite conduit promote functional recovery after peripheral nerve injury in rats

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Neural Regeneration Research 2024年第4期19卷 900-907页

作者： Haoshuai Tang Junjin Li Hongda Wang Jie Ren han ding Jun Shang Min Wang Zhijian Wei Shiqing Feng Department of Othopaedics Tianjin Medical University General Hospital International Science and Technology Cooperation Base of Spinal Cord Injury Tianjin Key Laboratory of Spine and Spinal Cord InjuryDepartment of OrthopedicsTianjin Medical University General Hospital Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment Tianjin Lung Cancer InstituteTianjin Medical University General Hospital Department of Othopaedics Qilu Hospital of Shandong UniversityShandong University Centre for OthopedicsAdvanced Medical Research InstituteShandong University Orthopedic Research Center of Shandong University&Advanced Medical Research Institute Cheeloo College of MedicineShandong University

Complete transverse injury of peripheral nerves is challenging to *** secreted by human umbilical cord mesenchymal stem cells are considered to play an important role in intercellular communication and regulate tissue *** previous studies,a collagen/hyaluronic acid sponge was shown to provide a suitable regeneration environment for Schwann cell proliferation and to promote axonal *** three-dimensional(3D)composite conduit contains a collagen/hyaluronic acid inner sponge enclosed in an electrospun hollow poly(lactic-co-glycolic acid)***,whether there is a synergy between the 3D composite conduit and exosomes in the repair of peripheral nerve injury remains *** this study,we tested a comprehensive strategy for repairing long-gap(10 mm)peripheral nerve injury that combined the 3D composite conduit with human umbilical cord mesenchymal stem cell-derived *** effectiveness was evaluated by sciatic functional index,sciatic nerve compound muscle action potential recording,recovery of muscle mass,measuring the cross-sectional area of the muscle fiber,Masson trichrome staining,and transmission electron microscopy of the regenerated nerve in *** results showed that transplantation of the 3D composite conduit loaded with human umbilical cord mesenchymal stem cell-derived exosomes promoted peripheral nerve regeneration and restoration of motor function,similar to autograft *** CD31-positive endothelial cells were observed in the regenerated nerve after transplantation of the loaded conduit than after transplantation of the conduit without exosomes,which may have contributed to the observed increase in axon regeneration and distal nerve ***,the use of a 3D composite conduit loaded with human umbilical cord mesenchymal stem cell-derived exosomes represents a promising cell-free therapeutic option for the treatment of peripheral nerve injury.

关键词： axon growth collagen exosome human umbilical cord mesenchymal stem cells hyaluronic acid muscular atrophy nerve guidance conduits peripheral nerve regeneration

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基于NaYF4:Yb,Er上转换发光纳米材料的掌印和足迹增强显现

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分析化学 2023年第11期51卷 1774-1782页

作者：丁寒中国政法大学刑事司法学院

以稀土硬脂酸盐为前驱体、乙醇-水-油酸混合溶剂为反应介质，采用溶剂热法制备了NaYF4:Yb,Er上转换发光纳米材料，并对其微观形貌、晶体结构、光学性质和表面基团等进行了表征。所制备材料的微观形貌为平均直径19.2 nm的单分散类球形颗... 详细信息

以稀土硬脂酸盐为前驱体、乙醇-水-油酸混合溶剂为反应介质，采用溶剂热法制备了NaYF4:Yb,Er上转换发光纳米材料，并对其微观形貌、晶体结构、光学性质和表面基团等进行了表征。所制备材料的微观形貌为平均直径19.2 nm的单分散类球形颗粒，晶体结构为六方晶系，在976 nm处出现了尖锐的近红外吸收峰，在980 nm近红外光激发下，在521、540和654 nm处产生较强的荧光发射峰，其表面被油酸分子修饰。将此发光纳米材料应用于潜在掌印、赤足足迹、穿鞋足迹的荧光增强显现，并对痕迹显现的具体效果进行了定性和定量评价。结果表明，痕迹显现信号与客体背景噪声之间的对比反差明显，具有较强的显现对比度；显现痕迹的各级特征均反映清晰精细，具有较高的显现灵敏度；显现材料与痕迹物质之间的特异性结合程度较高，具有较好的显现选择性。基于NaYF4:Yb,Er上转换发光纳米材料的掌印和足迹增强显现方法为痕迹的显现方法研究提供了新思路和有益参考。

关键词：掌纹显现足迹显现上转换发光纳米材料

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Clinical features of dementia with lewy bodies in 35 Chinese patients

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Translational Neurodegeneration 2014年第1期3卷 1-5页

作者： ding han Qiong Wang Zhongbao Gao Tong Chen Zhenfu Wang Department of Neurology South BuildingGeneral Hospital of Chinese PLABeijing 100853China

Objective:To investigate the clinical features of dementia with Lewy bodies(DLB)in a Chinese ***:Computer-based online searches through China Biology Medicine disc and China National Knowledge Infrastructure were performed to collect case reports of DLB published between 1980 and *** characteristics were ***:A total of 18 studies comprising 35 patients(26 males and 9 females)were *** mean age at onset was 67.2±9.8 *** was characterized by memory impairment and accounted for 58.8%of all cases,followed by parkinsonism(11.8%),visual hallucinations(8.8%),and compulsive personality disorder(2.9%).The other patients(17.6%)presented two of the three core features of DLB at *** disease progression,parkinsonism was reported in 100%of cases,followed by visual hallucinations(97.1%),psychiatric symptoms(85.7%),severe neuroleptic sensitivity(81.8%),fluctuating cognition(68.6%),repeated falls(40.0%),sleep disorders(22.9%),and transient loss of consciousness(17.1%).26 patients who were subjected to Mini-Mental State Examination scored≤24.10 patients presented relative preservation of hippocampus and medial temporal lobe structures on CT/MRI *** hypometabolism occurred in 2 of 3 patients who underwent SPECT/PET perfusion scan.12 patients showed an increasing of slow frequency activity on EEG,prominently in frontal and temporal ***:DLB often strikes elderly *** clinical core features are dementia,fluctuating cognition,recurrent visual hallucinations and spontaneous features of ***,neuroimaging and EEG examinations may improve the diagnostic accuracy and discriminate DLB from other dementias.

关键词： Dementia with Lewy bodies Secondary literature evaluation Clinical features Neurodegenerative disease

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Nucleophilic substitution of hydrogen in naphthalene by chloride(Cl^-)in ionic liquids

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Chinese Chemical Letters 2011年第2期22卷 147-150页

作者： Shen Yi Shi Ai Guo Kong Xin Hua Zhao han Ming ding Fan Yang Yong Kui Shan Department of Chemistry East China Normal UniversityShanghai 200062China

Nucleophilic aromatic substitution of hydrogen in non-activated aromatic ring,a very rare phenomenon in organic chemistry,is found in ionic liquids containing Cl^- as anion under mild reaction *** reaction may be carried out by the addition of the halogen-bonding adduct（Br2Cl^-） as nucleophile to aromatic ring carbon atom,leading to the formation of the nucleophilic substitution product.

关键词： Ionic liquid Aromatic compound Naphthalene Nucleophilic reaction Halogen bonding

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基于YVO4∶Eu纳米发光材料的足迹增强显现

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光谱学与光谱分析 2021年第1期41卷 88-93页

作者：丁寒王猛中南财经政法大学刑事司法学院湖北武汉430073 中国刑事警察学院刑事科学技术学院辽宁沈阳110035

足迹显现技术一直是刑事科学技术领域中的关键技术之一,也是足迹分析与足迹鉴定的重要前提。本研究在借鉴手印纳米荧光显现技术先进研究成果的基础上,提出了基于YVO4∶Eu纳米发光材料的足迹增强显现技术,旨在改善提升足迹的显现效果。... 详细信息

足迹显现技术一直是刑事科学技术领域中的关键技术之一,也是足迹分析与足迹鉴定的重要前提。本研究在借鉴手印纳米荧光显现技术先进研究成果的基础上,提出了基于YVO4∶Eu纳米发光材料的足迹增强显现技术,旨在改善提升足迹的显现效果。以稀土硝酸盐和原钒酸钠为原料、柠檬酸三钠为表面修饰剂,利用水热法合成出适于足迹显现的YVO4∶Eu纳米发光材料。采用透射电子显微镜、X射线衍射谱、紫外可见吸收光谱、荧光光谱、傅里叶变换红外光谱对该纳米发光材料的微观形貌、晶体结构、吸收性质、发光性能、表面基团进行表征。所合成的YVO4∶Eu纳米发光材料其微观形貌为类球形、平均粒径为39.2 nm,其晶体结构为四方晶系,紫外最强吸收波长为257 nm,在254 nm紫外光激发下能够发射614 nm红色可见光,表面为柠檬酸分子修饰。研究最终将YVO4∶Eu纳米发光材料应用于赤足足迹和穿鞋足迹的增强显现技术,并详细探讨了两种类型足迹的粉末法显现原理。赤足足迹显现结果表明,足迹的形态轮廓分明,乳突纹线连贯,细节特征明显,屈肌褶纹、脱皮、附着物等特征反映明显;穿鞋足迹显现结果表明,足迹的鞋底花纹特征完整明显,以上显现痕迹特征均能够达到足迹检验鉴定的要求。另外,该研究分别探讨了纳米材料的发光性能、颗粒尺寸、微观形貌对于提高足迹显现对比度、灵敏度、选择性的具体作用。该研究提出的基于YVO4∶Eu纳米发光材料的足迹增强显现技术具有对比度强、灵敏度高、选择性好等一系列显著优势,为稀土发光纳米材料的研究拓展了应用范围,也为足迹显现传统方法的发展提供了创新思路。

关键词：稀土发光纳米材料足迹显现

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