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Synthesis and characterization of NaYF4:Yb3+,Er3+@silica-N=folic acid nanocomplex for bioimaginable detecting MCF-7 breast cancer cells

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Journal of Rare Earths 2019年第11期37卷 1183-1187页

作者： ha thi phuong Tran Thu Huong Le thi Vinh Hoang thi Khuyen Do thi Thao Nguyen Thanh Huong Pham thi Lien Le Quoc Minh Institute of Materials Science Vietnam Academy of Science and Technology18 Hoang Quoc VietCau GiayHanoiViet Nam Graduate University of Science and Technology-Vietnam Academy of Science and Technology 18 Hoang Quoc VietCau GiayHanoiViet Nam Department of Chemistry Hanoi Medical University1-Ton That TungDong DaHanoiViet Nam Department of Chemistry Hanoi University of Mining and Geology18-Pho LienBac Tu LiemHanoiViet Nam Institute of Biotechnology Vietnam Academy of Science and Technology18-Hoang Quoc VietCau GiayHanoiViet Nam Duy Tan University K7/25 Quang TrungDa NangViet Nam

Upconversion nanophosphors are new promising nanomaterials to be used as biolabels for detection and imaging of cancer *** nanophosphors absorb long-wavelength excitation radiation in the infrared or near infrared region and emit shorter wavelength,higher energy radiation from ultraviolet to *** this paper,we studied the hydrothermal method and optical properties of the functionalized NaYF4:Yb^3+,Er^3+for biomedical *** synthesis,these NaYF4:Yb^3+,Er^3+nanophosphors were functionalized with aminosilanes and folic *** acid binds to the folate receptor on the surface of MCF-7 breast cancer cells and this binding promotes internalization of the nanophosphors via *** sizes of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA(folic acid)nanophosphors can be controlled with length of the rod about 300-800 nm and diameter of the rod about 100-200 *** structure of NaYF4:Yb^3+,Er^3+is in hexagonal crystal *** photo luminescence(PL)spectra of the functionalized NaYF4:Yb^3+,Er^3+@silica-N=FA nanophosphors were *** nanophosphors emit in red color with the strongest band at 650 nm under 980 nm *** result can provide NaYF4:Er^3+,Yb^3+@silica-N=FA complex for developing fluorescence label and image tool in cancer biology and medicine.

关键词： Upconversion luminescence NaYF4:Yb^3+,Er^3+ Nanophosphors Bioimaging Cancer cell Rare earths

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Polygonatum kingianum rhizome extract alleviates collagen antibody-induced arthritis by modulating proinflammatory cytokine production in mice

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Asian Pacific Journal of Tropical Biomedicine 2020年第11期10卷 490-495页

作者： Huyen Do thi Thanh phuong Ngo thi Hien Nguyen thi Thu Nga Nguyen thi Hung Le Ngoc Thao Dothi ha Le Minh Graduate University of Science and Technology Vietnam Academy of Science and Technology18 Hoang Quoc VietNghia DoCau GiayHanoiVietnam Institute of Natural Products Chemistry Vietnam Academy of Science and Technology18 Hoang Quoc VietNghia DoCau GiayHanoiVietnam hanoi Open University101 Nguyen Hien str Hai Ba Trung Dist.HanoiVietnam Laboratory of Bioassay Institute of BiotechnologyVietnam Academy of Science and Technology18 Hoang Quoc VietNghia DoCau GiayHanoiVietnam Chemistry Lab Project Center for Research and Technology transferVietnam Academy of Science and Technology18 Hoang Quoc VietNghia DoCau GiayHanoiVietnam

Objective: To evaluate the anti-arthritic effects of Polygonatum kingianum rhizome extract using both in vitro and in vivo ***: Lipopolysaccharide-induced RAW 264.7 macrophages were treated with an ethanol extract of Polygonatum kingianum rhizomes at different concentrations to determine nitric oxide and prostaglandin E2(PGE2) production. For in vivo study, Polygonatum kingianum ethanol extract was further investigated for its antiinflammatory effect in a mouse model with collagen antibodyinduced arthritis. Phytochemical study of Polygonatum kingianum ethanol extract was also ***: Saponins(142 mg/g total yield) was the main component in the Polygonatum kingianum ethanol extract. 5α,8α-ergosterol peroxide,(E,E)-9-oxooctadeca-10,12-dienoic acid and 3-(2?-hydroxy-4?-methoxy-benzyl)-5,7-dihydroxy-8-methyl-chroman-4-one were isolated from the extract. Polygonatum kingianum ethanol extract exhibited potential anti-inflammatory effects by inhibiting nitric oxide and PGE2 production in RAW 264.7 cells in a dosedependent manner. The level of arthritis in mice with collagen antibody-induced arthritis was significantly reduced(Phanol extract, particularly at a dose of 1 000 mg/kg body weight. Besides, the extract demonstrated the regulatory effects on serum tumor necrosis factoralpha, interleukin-6, and interleukin-10 in treated ***: Polygonatum kingianum ethanol extract has beneficial effects on inflammatory cytokine regulation and PGE2 inhibition in an experimental mouse model with collagen antibody-induced arthritis. The phytochemical screening reveals that the saponin, as the main component, and sterols(daucosterol and 5α,8α-ergosterol peroxide) from Polygonatum kingianum ethanol extract may contribute to its promising in vitro and in vivo anti-inflammatory activities.

关键词： inflammatory cytokine PGE2

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Comparative Chemical Research in Essential Oils from Six Apiaceae Species Growing in the Northern Region of Vietnam

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1677-1687页

作者： Nguyen Quang Hung Nguyen Thanh Tung Nguyen phuong hanh Chu thi Thu ha Nguyen thi Nhung Nguyen Thai An Vu Xuan Giang Luong Van hao Oleh Koshovyi Ain Raal Institute of Ecology and Biological Resources Vietnam Academy of Science and Technology(VAST)Cau GiayHa Noi100000Viet Nam Graduate University of Science and Technology Vietnam Academy of Science and Technology(VAST)Cau GiayHa Noi100000Viet Nam Department of Pharmacognosy Faculty of Pharmacognosy and Traditional MedicineHanoi University of PharmacyHoan KiemHa Noi100000Viet Nam Sa Pa Research Center of Medicinal Materials National Institute of Medicinal MaterialsDien Bien PhuSa PaLao Cai330000Viet Nam Institute of Pharmacy Faculty of MedicineUniversity of TartuTartu50411Estonia

Our study aimed to compare the essential oil(EO)concentration and composition of several Apiaceae species growing in the Northern region of *** yields of EOs from materials ranged from 0.03%(root EO of Angelica acutiloba and aerial parts EO of Heracleum bivittatum)-0.27%(leaf EO of Xyloselinum vietnamense).Gas chromatography-mass spectrometry(GC-MS)allowed the identiﬁcation of 74 components in the EOs of six Apiaceae species,making up 94.4%–100.0%of the *** EO from Angelica acutiloba,(Z)-ligustilide accounted for an extremely large proportion(94.9%).EO of Angelica pubescens was dominated by six character-istic components includingα-pinene(21.5%),β-phellandrene(18.1%),p-cymene(12.2%),3-methylnonane(8.7%),o-cymene(8.1%),and D-sylvestrene(6.2%).The EO from Cryptotaenia japonica was characterized by high amounts ofα-selinene(48.7%),β-selinene(23.7%),and trans-β-farnesene(5.4%).The EOs from leaves and stems of Xyloselinum vietnamense were characterized by high concentrations of sabinene(69.8%and 33.8%),4-terpineol(8.7%and 7.4%)andβ-pinene(4.0%and 6.5%)while EOs from aerial parts and root of Xylo-selinum leonidii comprise four characteristic monoterpenes includingα-pinene(28.2%and 52.8%),β-pinene(7.9%and 10.3%),β-phellandrene(7.6%and 15.3%),and sabinene(3.0%and 4.1%).Additionally,cryptone is also one of the major components in the EO of Xyloselinum leonidii(13.2%in the aerial parts oil and 2.8%in the root oil).In the EOs isolated from the aerial parts and root of Heracleum bivittatum,α-pinene(22.5%and 70.2%)andβ-pinene(43.2%and 20.0%)were the predominant *** appeared in the EO from aerial parts of Heracleum bivittatum with a relatively high concentration(13.5%)while bornyl acetate(5.1%)was also one of the main components in the EO from its aerial parts but was not detected in other Apiaceae species in the present *** databases help identify and control the quality of plant material studied from the family Apiaceae growing in Vietnam.

关键词： Apiaceae essential oil terpenoids gaschromatography-mass spectrometry

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Evaluation of Weathering Performance of Rosin-Copper Based Treated Wood

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Journal of Renewable Materials 2022年第11期10卷 2765-2780页

作者： thi Thanh Hien Nguyen Nho Quyet Tran thi Minh Nguyet Nguyen Hien Mai Trinh Xuan phuong Le Trong Kien Nguyen College of Wood Industry and Interior Design Vietnam National University of ForestryHa NoiViet Nam College of Economics and Management Northeast Forestry UniversityHarbinChina

this study aimed to evaluate the effect of natural weathering on some surface characteristics and mechanical properties of Styrax wood treated with mixtures of 1.0%,2.0%,or 4.0%rosin sizing agent and 3%copper *** samples after treatment were exposed to outdoor conditions for one year and changes in color,glossiness,weight loss,compression strength parallel to grain(CSPG),modulus of rupture(MOR),and modulus of elasticity(MOE)were investigated after 6 and 12-month of natural *** results showed that rosin-copper treatment could improve color stability and gloss of samples after *** losses of all rosin-copper treated samples after 12 months of exposure were negligible compared with the untreated control *** addition,rosin-copper treatment enhanced the CSPG compared to untreated controls,but slightly decreased the MOR and MOE of Styrax wood before *** weathering factors induced a reduction for all strength properties,however,the decrease rate for strength properties of rosin-copper treated samples was negligible compared with the untreated control samples after 12-month natural weathering *** FTIR and SEM-EDX confirmed that the use of the rosin-copper formulations to impregnate wood could decrease the hazard of the copper preservative leaching into the environment,while also enhancing more resistance against weathering factors and other biotic factors.

关键词： Rosin-copper weathering color stability CSPG MOR MOE

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Dry eye rate and its relationship with disease stage in patients with primary hypertension:a cross-sectional study in Vietnam

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 653-658页

作者： Tran Tat Thang Pham Hong phuong Nguyen Sa Huynh Nguyen Trung Kien NguyenDuy Toan Nguyen thi Thu ha Le ha Khoa Nguyen Huu Dung Thai Doan Thang Le Viet Thang Nghe An Eye Hospital Nghe An 43000Vietnam Nghe An Friendship General Hospital Nghe An 43000Vietnam Military Hospital 103 Ha Noi 100000Vietnam Vietnam Military Medical University Ha Noi 100000Vietnam hanoi Medical University Ha Noi 100000Vietnam Bạch Mai Hospital Ha Noi 100000Vietnam TTH Vinh General Hospital Nghe An 100000Vietnam

AIM:To determine the dry eye(DE)rate and its relationship with disease stage in patients with primary ***:A cross-sectional study included 432 patients with primary hypertension(with an equal number of patients in each group:144 in stage Ⅰ,Ⅱ,and Ⅲ hypertension)and 144 healthy subjects as a control *** Ocular Surface Disease Index(OSDI)and Schirmer Ⅰ test without anesthetics were conducted on all 576 *** with OSDI scoreshan in the control group(41.7%versus 18.8%;Phan those without DE,P<*** age,a long duration of hypertension,diabetes mellitus,elevated plasma creatinine,and CRP-hs levels were independent factors associated with DE in primary hypertension patients,P<***:DE is a common disorder associated with advanced age,a long duration of hypertension,diabetes mellitus,elevated plasma CRP-hs,and creatinine levels in patients with primary hypertension.

关键词： primary hypertension dry eye stage of hypertension plasma creatinine

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An imaging spectrometer employing tunable hyperchromatic microlenses

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Light(Science & Applications) 2015年第1期4卷 33-41页

作者： phuong-ha Cu-Nguyen Adrian Grewe Patrik Feßer Andreas Seifert Stefan Sinzinger hans Zappe Gisela and Erwin Sick Chair of Micro-optics Department of Microsystems EngineeringUniversity of FreiburgFreiburg 79110Germany Fachgebiet Technische Optik Institut fur Mikro-und NanotechnologienTechnische Universitat IlmenauIlmenau 98684Germany

We present the design,fabrication and characterization of hydraulically-tunable hyperchromatic lenses for two-dimensional(2D)spectrally-resolved spectral *** hyperchromatic lenses,consisting of a positive diffractive lens and a tunable concave lens,are designed to have a large longitudinal chromatic dispersion and the images of different wavelengths from each other.2D objects of different wavelengths can consequently be imaged using the tunability of the lens *** hyperchromatic lens concepts are demonstrated and their spectral characteristics as well as their functionality in spectral imaging applications are shown.

关键词： hyperchromatic lens imaging spectrometer tunable filter tunable lens

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Effectiveness of bee venom acupuncture for patients suffering from periarthritis humeroscapularis

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Journal of Traditional Chinese Medicine 2023年第4期43卷 795-800页

作者： Minh Duc Nguyen Thanh Van Tran Quoc Vinh Nguyen Cay Doan ha Linh Vu phuong Dang Senior Specialist Clinic National Hospital of AcupunctureHanoi 1000Vietnam Department of Senior Specialist National Hospital of Acupuncture Hanoi 1000Vietnam Department of Senior Specialist Military Institute of Traditional MedicineHanoi 1000Vietnam Department of minimally invasive spine National Hospital of AcupunctureHanoi 1000Vietnam Department of Medicine Dai Nam UniversityHanoi 1000Vietnam

OBJECTIVE:To evaluate the efficacy of bee venom acupuncture in humeroscapularis(PHS)***:One hundred and twenty patients diagnosed with PHS were assigned into four groups:BV1(0.01 mg/kg),BV2(0.005 mg/kg),BV3(0.0025 mg/kg),and control group(vitamin B1 plus novocain 3%injection)with 15 d of *** outcomes of the study including visual analogue scale(VAS)score andβ-endorphin,inflammatory cytokines including interleukin-10(IL-10),IL-1βand tumor necrosis factorα(TNF-α)and shoulder function score were assessed at baseline,after 10 and 15 d of ***:All four groups reported statistically significant improvement in VAS score,motion range,and shoulder function score(Phan current therapy used in Vietnam and other groups.

关键词： periarthritis humeroscapularis bee venom acupuncture visual analogue scale range of motion articular shoulder function score inflammatory cytokines

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A tree-based intelligence ensemble approach for spatial prediction of potential groundwater

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International Journal of Digital Earth 2020年第12期13卷 1408-1429页

作者： Mohammadtaghi Avand Saeid Janizadeh Dieu Tien Bui Viet Hoa Pham phuong Thao T.Ngo Viet-ha Nhu Faculty of Natural Resources and Marine Sciences Tarbiat Modares UniversityTehranIran Geographic Information Science Research Group Ton Duc Thang UniversityHo Chi Minh CityVietnam Faculty of Environment and Labour Safety Ton Duc Thang UniversityHo Chi Minh CityVietnam Ho Chi Minh City Institute of Resources Geography Vietnam Academy of Science and TechnologyHo Chi Minh CityVietnam Institute of Research and Development Duy Tan UniversityDa NangVietnam Department of Geological-Geotechnical Engineering Hanoi University of Mining and GeologyHanoiVietnam

The objective of this research is to propose and confirm a new machine learning approach of Best-First tree(BFtree),AdaBoost(AB),MultiBoosting(MB),and Bagging(Bag)ensembles for potential groundwater mapping and assessing role of influencing *** Yasuj-Dena area(Iran)is selected as a case *** this regard,a Yasuj-Dena database was established with 362 springs locations and 12 groundwater-influencing factors(slope,aspect,elevation,stream power index(SPI),length of slope(LS),topographic wetness index(TWI),topographic position index(TPI),land use,lithology,distance from fault,distance from river,and rainfall).The database was employed to train and validate the proposed groundwater *** area under the curve(AUC)and statistical metrics were employed to check and confirm the quality of the *** result shows that the BFTree-Bag model(AUC=0.810,kappa=0.495)has the highest prediction performance,followed by the BFTree-MB model(AUC=0.785,kappa=0.477),and the BFTree-MB model(AUC=0.745,kappa=0.422).Compared to the benchmark of Random Forests,the BFTree-Bag model performs better;therefore,we conclude that the BFtree-Bag is a new tool should be used for modeling of groundwater potential.

关键词： Environmental modeling groundwater potential GIS ensemble model decision tree

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Evaluation of Agronomic Characteristics,Drought Tolerance and Yield of Some Rice Varieties in Central Vietnam

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Journal of Agricultural Science and Technology(A) 2017年第B10期7卷 1-9页

作者： Phan thi phuong Nhi Tran thi Huong Sen Trinh thi Sen Tran thi Hoang Dong Faculty of Agronomy University of Agriculture and ForestryHue University102 Phung Hung StreetHue 530000Vietnam

The aim of the study was to evaluate the drought tolerance,agro-morphological characteristics and yield of 10 rice varieties collected from different *** experiment one,drought tolerance of rice varieties under artificial drought condition in the greenhouse was assessed through root and leaf *** experiment two,the growth and yield of rice varieties in the rainfed rice field was *** results showed that drought has affected the root characteristics,leaf rolling and leaf drying of these *** rainfed rice field of Thua thien Hue and Quang Nam province,summer-autumn 2016 and winter-spring 2016-2017 crop season,these rice varieties grew and developed *** growth time was 90-119 d in summer-autumn crop season,while in winter-spring crop season was 107-131 *** yield of these rice varieties ranged from 37.02 quintals/ha to 56.33 quintals/ha and from 42.33 quintals/ha to 66.60 quintals/ha,*** rice varieties with high yields in both two crop seasons were OM4900,GSR38,IR93340 and *** is sugessted to conduct production experiment on a large area in rainfed field for these four varieties to evaluate them objectively and early put them into structure of rice varieties in Central Vietnam.

关键词： Central Vietnam drought tolerance growth rice variety yield

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Study on Reproductive Performance of Terapon jarbua(Forsskal,1775)in Tam Giang-Cau hai Lagoon Systems,Thua thien Hue Province

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Journal of Agricultural Science and Technology(A) 2017年第B10期7卷 93-97页

作者： Le thi Nhu phuong Nguyen Quang Linh ha Long University Uong Bi City 200000Quang Ninh ProvinceVietnam Institute of Biotechnology Hue UniversityPhu ThuongPhu VangThua Thien Hue 530000Vietnam

Terapon jarbua was collected from Tam Giang-Cau hai lagoon systems and then their reproductive performances were *** 342 species were caught by otter trawlers and different fishing gears in marine and Tam Giang-Cau hai lagoon systems on certain days of each month during period from September 2015 to August 2016 at fishing *** determination of age was based on composition of the fish:ear,scaly,spine,gill cover and spine and the ovarian histology *** gonads after being fixed with Bouins solution were cleansed,cut,dyed and put on the observation *** showed that the sex of Terapon jarbua was nearly clarified at the approximately 1+age group and participated in reproduction process in the first time at the 1+age *** batch and relative fecundity of Terapon jarbua were *** batch fecundity of Terapon jarbua varied from 239,029 to 420,400 *** relative fecundity capacity fluctuated from 945 to 1,013 of eggs per gram of fish and the mean value by 981 eggs per gram of *** spawning season of fish occurred from March to May annually.

关键词： Terapon jarbua reproductive biology Thua thien Hue

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