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Plasma Science and Technology 2019年第6期21卷 52-57页

作者： h j yeom D h ChOI Y S LEE j h KIM D j SEONG S j YOU h C LEE Korea Research Institute of Standards and Science(KRISS) Daejeon 34113 Republic of Korea Department of Physics Chungnam National University Daejeon 34134 Republic of Korea

In this study,plasma density measurements were performed near the plume region of the remote plasma source (RPS) in Ar/NF3 gas mixtures using a microwave cutoff *** measured plasma density is in the range of 1010-1011 cm-3 in the discharge conditions with RPS powers of 2-4 kW and gas pressures of 0.87-4 *** plasma density decreased with increasing gas pressures and RPS powers under various Ar/NF3 mixing *** decrease in the plasma density measured at the fixed measurement position (plume region) can be understood by the reduction of the electron energy relaxation length with increases in the gas pressures and mixing ratio of NF3/(Ar/NF3).We also performed downstream etching of silicon and silicon oxide films in this *** etch rate of the silicon films significantly increases while the silicon oxide is slightly etched with the gas pressures and *** was also found that the etch rate strongly depends on the wafer position on the processing chamber electrode,and that the etch selectivity reached 96-131 in the discharge conditions of RF powers (3730-4180 W) and gas pressures (3.6-4 Torr).

关键词： remote plasma source electron density cutoff probe downstream etch

Experimental Status of the hANBIT Facility

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Plasma Science and Technology 2004年第4期6卷 2367-2370页

作者： S.j.Yoo M.Kwon j.G.Bak K.Choh I.S.Choi j.h.Choi j.W.Choi A.C.England j.hong h.S.jeon h.G.jhang j.S.ju M.jung j.Y.Kim S.S.Kim W.h.Ko K.Y.Kwak M.C.Kyum B.j.Lee D.K.Lee j.h.Lee h.G.Lee S.G.Lee T.Lho h.K.Na B.h.Park M.K.Park D.C.Seo S.h.Seo j.h.yeom j.S.Yoon K.I.You Korea Basic Science Institute Daejeon305-333Korea hanbit User Group

hANBIT is a magnetic mirror confinement device. Recent physics experimentshave been mainly focused on identifying discharge characteristics and on getting stable plasmaproduction and operation modes, by using a 500 kW slot antenna system at a fixed RF frequency of 3.5Mhz and varying discharge conditions such as fueling rate, RF power, and B-field intensity incentral cell. Two distinct operation modes are found to be very sensitive to the RF power as well asthe ratio of the RF frequency to the ion cyclotron frequency. A MhD interchange mode of m = - 1 isclearly observed and the stabilizing mechanism can be explained by the sideband coupling theory.

关键词： mirror discharge stabilization

Superelastic metastable Ti-Mo-Sn alloys with high elastic admissible strain for potential bio-implant applications

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journal of Materials Science & Technology 2023年第32期163卷 45-58页

作者： Shuanglei Li jae h.Kim Seung Won Kang jae ho Kim Tae-hyun Nam jong-Taek yeom Titanium Alloys Department Metal Materials DivisionKorea Institute of Materials Science(KIMS)Changwon 51508Republic of Korea Department of Materials Engineering and Convergence Technology&Research Institute for Green Energy Convergence Technology(RIGET) Gyeongsang National University900 GazwadongJinjuGyeongnam 52828Republic of Korea

The demand for titanium alloys simultaneously having high elastic admissible strain and large recovery strain for bio-implant applications is ***-free Ti-based shape memory alloys are promising candidates for obtaining the required multifunctional *** this study,a wide content range of(0-15)wt%of low-cost,toxicity-free,and high-biocompatible Sn element was added to the Ti-8Mo(wt%)alloy to study its effect on the superelastic recovery and mechanical properties of biomedical Ti-Mo-Sn *** tailoring Sn content,desired multifunctional properties of high elastic admissible strain and room temperature superelasticity were achieved in the studied Ti-Mo-Sn *** was found that the increase in Sn content stabilized theβphase and a singleβphase was obtained at room temperature in Ti-8Mo-(13,15)Sn *** addition of Sn modified the lattice parameters of theα″martensite andβphase and affected the lattice deformation stain ofβ→α″.The lattice deformation strain along the[011]βdirection was found to be decreased by-0.26%/wt%*** room temperature superelasticity with a recovery strain of 3.1%and an elastic admissible strain of 1%was obtained in the Ti-8Mo-13Sn *** Sn content increased to 15 wt%,a high elastic admissible strain of 1.56%and a recovery strain of 2.0%were *** Ti-Mo-Sn alloys with excellent multifunctional properties are promising candidates for bio-implant applications.

关键词： Ti-Mo-Sn alloy Shape memory alloy Elastic admissible strain Elastic modulus Superelasticity

Clinical,laboratory,and therapeutic differences between immunoglobulin E-mediated and non-immunoglobulin E-mediated cow’s milk protein allergy in children

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World journal of Clinical Pediatrics 2025年第1期14卷 78-92页

作者： hasan M Isa Marwa j Abdulnabi Nawra S Naser Fatema N Lahmda Noor M AlAnsari Zahra h Isa Afaf M Mohamed Department of Pediatrics Salmaniya Medical ComplexManama 26671Bahrain Department of Pediatrics Arabian Gulf UniversityManama 26671Bahrain Faculty of Medicine Mansoura UniversityMansoura 35516Egypt Public health Directorate Ministry of HealthManama 26671Bahrain

BACKGROUND Although breast milk is ideal for newborns,in some cases,it is replaced with cow’s milk,which contains proteins that increase the risk of cow’s milk protein allergy(CMPA).AIM To evaluate CMPA prevalence in Bahrain and compare clinical characteristics of children with immunoglobulin E(IgE)-and non-IgE-mediated *** This retrospective cohort study examined children with CMPA diagnosed at the pediatric gastroenterology outpatient clinic of the Salmaniya Medical Complex,Bahrain,between 2014 and 2022,and assessed CMPA *** presentations,laboratory findings,dietary modifications,and outcomes were compared between children with IgE-mediated and non-IgE-mediated *** variables were compared using Fisher’s exact test or Pearson’sχ2 test,whereas continuous variables were compared using Student’s t-test or the Mann-Whitney U *** Of 8332 patients,6022(72.3%)adhered to their *** them,618(10.3%)were suggested of having CMPA and 595(96.3%)were included;CMPA prevalence was 2%.Most patients were Bahraini(93.8%)and males(55.3%).Non-IgE-mediated type accounted for 77.3%cases and IgE-mediated type,22.7%.IgE-mediated CMPA presented more in boys(P=0.030),and later in life(5.1 months±4.5 months vs 4.2 months±4.2 months,P=0.016,95%CI:0.08-1.73),had more associated diseases(Ph more cutaneous(P=0.024)and respiratory(P=0.003)manifestations,severe symptoms[rash/dry skin(P=0.031),facial swelling/angioedema(P=0.003),failure to thrive(P=0.013),apparent life-threatening event(Physical findings(P=0.002)than non-IgE-mediated *** patients were exclusively fed cow milk formula(50.3%).The amino acid-based formula(AAF)was most prescribed(60.5%)with no difference between the two types(P=0.173).Although breastfeeding was recommended to 49.6%,only 8.2%were exclusively ***-mediated CMPA was associated with a longer follow-up duration than non-IgE-mediated CMPA(17.3 months±14.0 mo

关键词： Children Milk allergy Immunoglobulin E Breastfeeding Infant formula Bahrain

Microstructure and Mechanical Properties of TiB-Containing Al–Zn Binary Alloys

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journal of Materials Science & Technology 2016年第7期32卷 653-659页

作者： Sang-Soo Shin Gil-Yong yeom Tae-Yang Kwak Ik-Min Park Department of Materials Science and Engineering Pusan National University Busan 609-735 Republic of Korea Liquid Processing & Casting Technology R&BD Group Korea Institute of Industrial Technology Incheon 21999 Republic of Korea

The microstructure and mechanical properties of newly developed Al-35Zn cast alloys with TiB refiner addition were evaluated by X-ray diffractometry, optical microscopy, and scanning electron microscopy coupled with energy dispersive spectrometry. The microstructure of these alloys featured α-Al den- drites surrounded by AI-Zn （α ＋ rI） eutectic structures. After the addition of TiB refiner, the alloy grain sizes decreased, and its morphology abruptly changed from dendritic to equiaxed grains. Such an im- proved microstructure of the modified alloys was accompanied by a significant increase in the tensile strength and elongation percentage compared to those of the AI-Zn or Zn-Al-based alloys. The results showed that with the increase of TiB content up to 0.05%, the morphology of α-Al dendrites and α ＋ T1 phases changed from coarse dendrite and lamellar structures into independent and fine ones. Based on these results, the effect of TiB refiner addition on the microstructure and mechanical properties of the AI-35Zn binary alloys was investigated.

关键词： Al-Zn(-Cu) alloyEutectic structurehigh strengthTiB2

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon C.Daeschler Katelyn j.W.So Konstantin Feinberg Marina Manoraj jenny Cheung jennifer Zhang Kaveh Mirmoeini jPaul Santerre Tessa Gordon Gregory hBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

Rapid detection of influenza A(h1N1)virus by conductive polymer-based nanoparticle via optical response to virus-specific binding

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Nano Research 2022年第3期15卷 2254-2262页

作者： Geunseon Park hyun-Ouk Kim jong-Woo Lim Chaewon Park Minjoo yeom Daesub Song Seungjoo haam Department of Chemical&Biomolecular Engineering Yonsei UniversitySeoul 03722Republic of Korea Division of Chemical Engineering and Bioengineering College of Art Culture and EngineeringKangwon National UniversityChuncheon-siGangwon-do 24341Republic of Korea Biohealth-machinery Convergence Engineering Kangwon National UniversityChuncheonGangwon-do 24341Republic of Korea College of Pharmacy Korea UniversitySejong 30019Republic of Korea

A recurrent pandemic with unpredictable viral nature has implied the need for a rapid diagnostic technology to facilitate timely and appropriate countermeasures against viral *** this study,conductive polymer-based nanoparticles have been developed as a tool for rapid diagnosis of influenza A(h1N1)*** distinctive property of a conductive polymer that transduces stimulus to respond,enabled immediate optical signal processing for the specific recognition of h1N1 *** poly(aniline-co-pyrrole)-encapsulated polymeric vesicles,functionalized with peptides,were fabricated for the specific recognition of h1N1 *** low solubility of conductive polymers was successfully improved by employing vesicles consisting of amphiphilic copolymers,facilitating the viral titer-dependent production of the optical *** optical response of the detection system to the binding event with h1N1,a mechanical stimulation,was extensively analyzed and provided concordant information on viral titers of h1N1 virus in 15 *** specificity toward the h1N1 virus was experimentally demonstrated via a negative optical response against the control group,***,the designed system that transduces the optical response to the target-specific binding can be a rapid tool for the diagnosis of h1N1.

关键词： influenza A(h1N1)virus conductive polymer optical property rapid detection

Effects of Mg Enhancement and heat Treatment on Microstructures and Tensile Properties of Al2Ca-Added ADC12 Die Casting Alloys

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journal of Materials Science & Technology 2016年第10期32卷 1043-1048页

作者： Gil-Yong yeom hyun Kyu Lim Shae K.Kim Soong-Keun hyun Young-Ok Yoon Korea Institute of Industrial Technology lncheon 406-840 South Korea Department of Materials Science and Engineering Inha University lncheon 402-751 South Korea

The effects of Mg enhancement and heat treatment on the microstructures and tensile properties of Al_2Ca-added ADC12 die casting alloys were investigated. 0.3% and 0.5% Mg in the form of a master alloy including a trace amount of Al_2Ca were added to conventional ADC12（383 and AlSi10Cu2Fe） alloy with an initial Mg-content of 0.3% to increase the Mg content to 0.6% and 0.8%, respectively. To avoid heat treatmentinduced surface blisters, shortened solution treatment for 15 min at 490 ℃ and artificial aging for 6 h at 150 ℃ was undertaken. The results show that a 10% improvement in the shape factor of eutectic Si particles was achieved for Al_2Ca-added ADC12 with 0.8% Mg compared to the conventional ADC12 in the as-aged condition. Al_2Ca-added ADC12 with 0.8% Mg exhibited a yield strength of 289 MPa, a tensile strength of 407 MPa, and an elongation of 4.22%.

关键词： Al2Ca ADC12 alloy heat treatment Die casting Inclusion

A structural topological optimization method for multi-displacement constraints and any initial topology configuration

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Acta Mechanica Sinica 2010年第5期26卷 735-744页

作者： j. h. Rong j. h. Yi School of Automotive and Mechanical Engineering Changsha University of Science and TechnologyChangsha 410076 China

In density-based topological design, one expects that the final result consists of elements either black （solid material） or white （void）, without any grey areas. Moreover, one also expects that the optimal topology can be obtained by starting from any initial topology configuration. An improved structural topological optimization method for multidisplacement constraints is proposed in this paper. In the proposed method, the whole optimization process is divided into two optimization adjustment phases and a phase transferring step. Firstly, an optimization model is built to deal with the varied displacement limits, design space adjustments, and reasonable relations between the element stiffness matrix and mass and its element topology variable. Secondly, a procedure is proposed to solve the optimization problem formulated in the first optimization adjustment phase, by starting with a small design space and advancing to a larger deign space. The design space adjustments are automatic when the design domain needs expansions, in which the convergence of the proposed method will not be affected. The final topology obtained by the proposed procedure in the first optimization phase, can approach to the vicinity of the optimum topology. Then, a heuristic algorithm is given to improve the efficiency and make the designed structural topology black/white in both the phase transferring step and the second optimization adjustment phase. And the optimum topology can finally be obtained by the second phase optimization adjustments. Two examples are presented to show that the topologies obtained by the proposed method are of very good 0/1 design distribution property, and the computational efficiency is enhanced by reducing the element number of the design structural finite model during two optimization adjustment phases. And the examples also show that this method is robust and practicable.

关键词： Topological optimization Displacement constraint Continuum structure Design space adjustment Rational approximation material model

Optimal use of mobile cooling units in a deep-level gold mine

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International journal of Mining Science and Technology 2020年第4期30卷 547-553页

作者： h.j.van Staden j.F.van Rensburg h.j.Groenewald Centre for Research and Continued Engineering Development North-West UniversityPretoria 0081South Africa

The South African gold mining sector remains a significant contributor to the country’s *** several challenges that hinder the realisation of South Africa’s full mineral potential,the sector’s sustainability and profitability can be enhanced through implementing operational improvement *** cooling units(MCUs)were identified as a potential focus area for operational *** are used as tertiary or in-stope cooling in hot underground *** this paper,a method was presented to characterise the performance of existing MCUs based on three key performance indicators(KPIs),namely,the wet-bulb temperature ratio(WTR),efficiency and *** strategies were then elected and implemented based on these *** implementation of this method in a South African gold mine attained a reduction in pumped water volumes,reduced operating costs through electricity cost savings and improvements in underground ventilation air temperatures.

关键词： Mobile cooling units Optimisation Mine cooling performance Electricity cost savings Spot cooling