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Chinese Medical Journal 2024年第10期137卷 1228-1230页

作者： Jing Wang Jian Wang Sizhe gao Gang Liu Qian Wang Shujie Yan Boyi Zhou Yuan Yuan guodong gao Bingyang Ji Department of Cardiopulmonary Bypass Fuwai hospitalNational Center for Cardiovascular DiseaseChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100037China

To the Editor:Veno-arterial extracorporeal membrane oxygenation(VA-ECMO)has been used as a bridge in patients with advanced heart failure(AdHF)while waiting for heart transplantation(HTx).Many studies reported by developed countries have confirmed the advantages of VA-ECMO in terms of bridge to left ventricular assist device(LVAD)or HTx,with stabilizing the condition and improving the possibility of further treatment of patients.[1-3]Recent data from the Extracorporeal Life Support Organization(ELSO)[4]indicated that ECMO used as a bridge has increased by 20.5%over a ***,to date,there are few studies on the bridge experience of VA-ECMO in the mainland of China.

关键词： patients arterial ventricular

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体外膜肺氧合插管相关感染的研究进展

中华危重病急救医学 2024年第7期36卷 778-781页

作者：李昆雨高国栋中国医学科学院北京协和医学院国家心血管病中心阜外医院体外循环中心北京100037

体外膜肺氧合(ECMO)常用于心肺功能严重衰竭患者的过渡治疗,通过静脉插管引出未氧合的血液,经过氧合后再将血液输回动脉或静脉系统。动静脉插管存在插管相关感染的发生风险,感染一旦发生,会延长患者的住院时间,增加患者的病死率和医疗... 详细信息

体外膜肺氧合(ECMO)常用于心肺功能严重衰竭患者的过渡治疗,通过静脉插管引出未氧合的血液,经过氧合后再将血液输回动脉或静脉系统。动静脉插管存在插管相关感染的发生风险,感染一旦发生,会延长患者的住院时间,增加患者的病死率和医疗费用。较长的ECMO持续时间、较高的简化急性生理学评分(SAPS)等均是感染的危险因素。目前针对感染的主要诊断方法是血培养。超声引导下经皮穿刺置管可降低感染风险,若仍发生感染则需积极进行抗菌药物治疗。本文围绕ECMO插管相关感染,对其发生率、危险因素、诊断标准、预防策略、治疗方法等要点进行综述,以期为临床工作带来借鉴意义。

关键词：体外膜肺氧合医院感染危险因素插管

A water-stable organolead iodide material for overall photocatalytic CO_(2) reduction

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Nano Research 2022年第12期15卷 10084-10089页

作者： Rong Chen guodong gao Jingshan Luo Institute of Photoelectronic Thin Film Devices and Technology Solar Energy Research CenterKey Laboratory of Photoelectronic Thin Film Devices and Technology of TianjinMinistry of Education Engineering Research Center of Thin Film Photoelectronic TechnologyRenewable Energy Conversion and Storage CenterNankai UniversityTianjin300350China

The utilization of perovskites as photocatalysts to convert CO_(2) into fuels and chemicals has received wide attention ***,their instability in water hinders their long-term application for overall photocatalytic CO_(2) ***,we integrate the water-stable perovskite-like organolead iodide crystalline material[Pb8I8(H2O)3]8+[-O2C(CH2)4CO_(2)-]4(TJU-16)with Au co-catalyst for photocatalytic CO_(2) reduction in aqueous solution without sacrificial *** the AM 1.5 G simulated illumination,the TJU-16 with 0.19 wt.‰ Au co-catalyst steadily generated electrons for CO_(2) reduction reaction,which was 2.2 times of pure *** Au0.19/TJU-16 catalyzed CO_(2) reduction at a rate of 84.2μmol·g-1·h-1,and achieved a solar-to-fuel(STF)conversion efficiency of 0.034%.Our work will motivate the rational design of water-stable perovskite-like materials for photocatalytic applications.

关键词： water-stable organolead iodide photocatalytic CO_(2)conversion

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大落差马鞍形接管孔坡口加工技术

一重技术 2024年第1期 49-50,24,9页

作者：隋波高国栋海装沈阳局辽宁沈阳110000

大厚度、大落差马鞍形接管孔坡口为复杂空间曲面,因工件尺寸很大,接管孔所处位置只能用镗床编程加工,加工后无法保证尺寸精度,根部R角残留大,粗糙度亦无法保证,且加工效率低。基于此开发一种大厚度、大落差马鞍形接管孔坡口加工方法,解... 详细信息

大厚度、大落差马鞍形接管孔坡口为复杂空间曲面,因工件尺寸很大,接管孔所处位置只能用镗床编程加工,加工后无法保证尺寸精度,根部R角残留大,粗糙度亦无法保证,且加工效率低。基于此开发一种大厚度、大落差马鞍形接管孔坡口加工方法,解决大直径接管马鞍形坡口的加工难题。

关键词：马鞍形空间曲面加工残留

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基于机器视觉的牡蛎分级设备设计

食品与机械 2024年第4期40卷 78-83页

作者：赵澜锴高国栋孙子皓李响吴沄泽大连海洋大学航海与船舶工程学院辽宁大连116023

目的:提高牡蛎分级的精确性和全面性。方法:提出并设计了牡蛎自动化分级设备,确定了旋转滚筒与挡板传送带结合的牡蛎排队结构、质量检测和机器视觉检测相结合的分级方式,完成了牡蛎分级设备的整体结构设计。通过工业相机采集牡蛎图像,... 详细信息

目的:提高牡蛎分级的精确性和全面性。方法:提出并设计了牡蛎自动化分级设备,确定了旋转滚筒与挡板传送带结合的牡蛎排队结构、质量检测和机器视觉检测相结合的分级方式,完成了牡蛎分级设备的整体结构设计。通过工业相机采集牡蛎图像,使用大津法二值化、高斯滤波处理、Canny算子边缘提取等方法提取牡蛎图像,通过机器视觉算法以长度和饱满度为标准对牡蛎进行分级,并进行机器视觉分级与人工分级对比试验。结果:该设备分级准确率为95.4%,图像检测速度约为0.647 s/幅。结论:机器视觉对牡蛎分级是有效的,可以较为准确地对牡蛎进行分级。

关键词：牡蛎自动化分级机器视觉图像滤波饱满度检测

Reduced information transmission in the internal segment of the globus pallidus of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced rhesus monkey models of Parkinson's disease

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Neural Regeneration Research 2012年第26期7卷 2028-2035页

作者： Yan He Jue Wang guodong gao Guangjun Zhang The Key Laboratory of Biomedical Information Engineering of Ministry of Education and Institute of Biomedical Engineering School of LifeScience and Technology Xi'an Jiaotong University National Engineering Research Center of Health Care and Medical Devices Xi'anJiaotong University Branch Xi'an 710049 Shaanxi Province China Department ofNeurosurgery Tangdu Hospital Affiliated to the Fourth Military Medical University Xi'an 710038 Shaanxi Province China

Rhesus monkey models of Parkinson＇s disease were induced by injection of N-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine. Neural firings were recorded using microelectrodes placed in the interna segment of the globus pallidus. The wavelets and power spectra show gradual power reduction during the disease process along with increased firing rates in the Parkinson＇s disease state. Singular values of coefficients decreased considerably during tremor-related activity as well as in the Parkinson＇s disease state compared with normal signals, revealing that higher-frequency components weaken when Parkinson＇s disease occurs. We speculate that the death of neurons could be reflected by irregular frequency spike trains, and that wavelet packet decomposition can effectively detect the degradation of neurons and the loss of information transmission in the neural circuitry.

关键词： neuronal oscillation microelectrode Parkinson's disease wavelet packet decomposition singularvalue neural regeneration

Microfacies of Deep-water Deposits and Forming Models of the Chinese Continental Scientific Drilling-SKII

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Acta Geologica Sinica(English Edition) 2007年第6期81卷 1026-1032页

作者： CHENG Rihui WANG guodong WANG Pujun gao Youfeng College of Earth Sciences of Jilin University Changchun Jilin 130061

Extensive transgression of lake water occurred during the Cretaceous Qingshankou Stage and the Nengjiang Stage in the Songliao basin, forming widespread deep-water deposits. Eleven types of microfacies of deep-water deposits have been recognized in the continuous core rocks from the SKII, including mudstone of still water, marlite, dolostone, off shale, volcanic ashes, turbidite, slump sediment, tempestite, seismite, ostracoda limestone and sparry carbonate, which are divided into two types： microfacies generated due to gradually changing environments （Ⅰ） and microfacies generated due to geological events （Ⅱ）. Type Ⅰ is composed of some special fine grain sediments such as marlite, dolomite stone and oil shale as well as mudstone and Type Ⅱ is composed of some sediments related to geological events, such as volcanic ashes, turbiditie, slump sediment, tempestite, seismite, ostracoda limestone. The formation of sparry carbonate may be controlled by factors related to both environments and events. Generally, mudstone sediments of still water can be regarded as background sediments, and the rest sediments are all event sediments, which have unique forming models, which may reflect controlling effects of climatics and tectonics.

关键词： Cretaceous deep-water deposit model of microfacies Songliao basin SKII

Apoptosis of endothelial cells of cerebral basilar arteries in symptomatic cerebral vasospasm rabbit models Electron microscopic observation

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Neural Regeneration Research 2007年第8期2卷 479-482页

作者： Guojun Shi guodong gao Zhenwei Zha Fifth Endemic Area the 89 Hospital of Chinese PLA Weifang 261021 Shandong Province China Minimally Invasive Neurosurgical Center Tangdu Hospital Fourth Military Medical University of Chinese PLA Xi＇an 710038 ShaanxiProvince China

BACKGROUND： Recent researchers report that vasospasm is caused by that, on one hand, damage of endothelial cells reduces synthesis and liberation of vessel dilator; on the other hand, defluxion of endothelial cells directly exposure vascular smooth muscles in active materials of vasoconstriction in blood. OBJECTIVE： To study whether apoptosis of cerebrovascular cells occurs in symptomatic cerebral vasospasm （CVS） rabbit models by using transmission electron microscope. DESIGN： Contrast observation. SETTINGS： The Fifth Endemic Area, the 89 Hospital of Chinese PLA; Minimally Invasive Neurosurgical Center, Tangdu Hospital, the Fourth Military Medical University of Chinese PLA. MATERIALS： A total of 24 New Zealand rabbits, of either sex, weighing 2.4 - 3.0 kg, of clear grade, were selected from the Experimental Animal Center of the Fourth Military Medical University of Chinese PLA. JEM-2000EX transmission electron microscope was made in Japan. METHODS： The experiment was carried out in the Laboratory of Anatomy （National Key Laboratory）, the Fourth Military Medical University of Chinese PLA from April 2001 to April 2002. ①Preparation of symptomatic CVS models： Eighteen animals which were successfully modeled were randomly divided into experimental group （n =13） and control group （n =5）. Animals in the experimental group were poured with blood into cavitas subarachnoidealis; while, animals in the control group were poured with the same volume of saline into cavitas subarachnoidealis. At the 5^th day injection, three rabbits selected from the experimental group were anesthetized and perfused into left ventricle. And then, aorta pectoralis and caval vein were blocked by using ring clamp. Cranium was rapidly cut open to obtain cerebral basilar artery and a few of brain tissues. Both of them were fixed for 8 hours. Two rabbits selected from the control group were perfused with the same method to obtain basilar artery and brain tissues and fix. ②After fixation by using optic

关键词： encephalomyelitis models, animal autoimmunity

从先后天之本探讨肌少-骨质疏松症的中医药防治策略

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中华中医药杂志 2024年第3期39卷 1391-1394页

作者：李磊秦大平郑礼高国栋张晓刚宋敏徐斌王志鹏徐世伟权祯甘肃中医药大学兰州730000 甘肃中医药大学附属医院兰州730020

肌少-骨质疏松症(OS)是一种以肌少症和骨质疏松症并存的肌骨共退综合性疾病,其发病人群以老年人为主。近年来随着老龄化社会进程的加剧,OS的发病率增高,为家庭和社会造成了极大的经济负担,但目前针对肌肉和骨骼共同作用靶点的临床药物... 详细信息

肌少-骨质疏松症(OS)是一种以肌少症和骨质疏松症并存的肌骨共退综合性疾病,其发病人群以老年人为主。近年来随着老龄化社会进程的加剧,OS的发病率增高,为家庭和社会造成了极大的经济负担,但目前针对肌肉和骨骼共同作用靶点的临床药物还尚缺乏。中医认为“肾为先天之本,脾为后天之本”,肾主骨,脾主四肢肌肉,从先后天之本对骨骼和肌肉共同进行中医药论治,或可为防治OS提供新的研究思路和方法。

关键词：先天之本后天之本肌少症骨质疏松症肌少-骨质疏松症

从“温督启阳”理论探讨针灸治疗绝经后骨质疏松症的研究进展

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中国骨质疏松杂志 2024年第1期30卷 93-97页

作者：马姣姣权祯秦大平刘建军高国栋陈一新齐鑫张晓刚甘肃中医药大学中医临床学院甘肃兰州730000 甘肃中医药大学附属医院脊柱外科甘肃兰州730099

绝经后骨质疏松症以脾肾阳虚居多,针灸疗法在绝经后骨质疏松症的治疗中具有显著优势,针灸通过调理脾肾、温阳督脉功能,达到治疗骨质疏松症的临床目的。笔者通过综述中医学针灸古籍有关绝经后骨质疏松症(postmenopausal osteoporosis,PM... 详细信息

绝经后骨质疏松症以脾肾阳虚居多,针灸疗法在绝经后骨质疏松症的治疗中具有显著优势,针灸通过调理脾肾、温阳督脉功能,达到治疗骨质疏松症的临床目的。笔者通过综述中医学针灸古籍有关绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)的理论溯源,阐释祖国医学中PMOP的病因病机,以现在普通针灸、温针灸、电针、督脉灸、穴位埋线、穴位注射和火针等具体治疗方法,基于“温督启阳”理论从绝经后骨质疏松症的病因病机出发,从“督脉调节全身气血、先后天相互滋生”角度将针灸治疗机制与骨代谢相结合,为针灸治疗绝经后骨质疏松症提供新的治疗思路。

关键词：绝经后骨质疏松症温督启阳针灸疗法中医