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Science China Life Sciences 2025年第1期 297-299页

作者： Junbin Zhou Rongli Wei guanghan fan Zhengxing Lian Xuanyu Zhang Linsong Tang Zhetuo Qi Haiyang Xie Shusen Zheng Qiang Wei Xiao Xu Department of Hepatobiliary and Pancreatic Surgery People's Hospital of LishuiAffiliated Lishui Hospital of Wenzhou Medical UniversityThe First Affiliated Hospital of Lishui University NHFPC Key Laboratory of Combined Multi-Organ Transplantation Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Department of Hepatobiliary and Pancreatic SurgeryHangzhou First People's Hospital Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of Medicine Department of Urology The Second Affiliated HospitalZhejiang University School of Medicine Department of Hepatobiliary and Pancreatic Surgery Department of Liver TransplantationShulan (Hangzhou) Hospital Hangzhou Medical College Zhejiang University School of Medicine

Dear Editor, Liver transplantation(LT) is the only curative therapy for patients with endstage liver disease(He et al., 2023; Ling et al., 2022). Post-transplant hypertriglyceridemia(PTHT), which has an incidence of up to 32.8% in 6 months after LT, is one of the major post-transplant complications(Toshima et al., 2020).

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High Quality Zinc Sulfide Epitaxial Layers Grown by Metalorganic Chemical Vapour Deposition

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Rare Metals 1989年第2期9卷 37-42页

作者： fan, guanghan Liao, Qiwei fan, Xiwu Zhang, Zhishun Li, Mei Zhang, Jiying Changchun Inst of Physics China

ZnS films were successfully grown by metallorganic chemical vapour deposition (MOCVD) at atmospheric pressure on (100) GaAs substrates. The deposition was carried out at a substrate temperature between 280 approximately 550°C with optimisation of reactor design and growth conditions. The gas phase prereaction is effectively restrained. These epilayers exhibit high crystallographic quality and reveal a mirror surface morphology. The peak halfwidths of X-ray diffraction patterns from their (400) faces are within 0.06 approximately 0.09°. The epilayers grown on (111) GaAs, (112¯0) Al2O3 and (100) Si have proven to be single crystalline feature. The optical and electrical characteristics of ZnS epilayers are measured by photoluminescence, cathodeluminescence, and the Van der Pauw method. The results indicate that there are not a large number of deep centers that could be detected both at 77K and at room temperature. A broad CL peak around 2.897eV and 2.672eV was observed only under very strong excitation. Their origin has not been examined. All epilayers present high resistivities up to 1013Ω·cm.

关键词： Crystals Epitaxial Growth Optical Properties Measurements Organometallics Chemical Vapor Deposition Semiconducting Gallium Arsenide Substrates Semiconducting Zinc Compounds

Investigation of GaN-based light-emitting diodes using a p-GaN/i-InGaN short-period superlattice structure as last quantum barrier

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Science China(Technological Sciences) 2013年第1期56卷 98-102页

作者： LIU XiaoPing fan guanghan ZHENG ShuWen GONG ChangChun LU TaiPing ZHANG YunYan XU YiQin ZHANG Tao Institute of Opto-electronic Materials and Technology South China Normal University

In this work,GaN-based light-emitting diodes(LEDs) with a p-GaN/i-InGaN short-period superlattice(SPSL) structure,p-GaN and undoped GaN last quantum barrier(LQB) have been numerically investigated by using the APSYS simulation *** has been found that the efficiency droop is significantly improved when the undoped GaN LQB in a typical blue LED is replaced by a p-GaN/i-InGaN SPSL *** to the simulation analysis,using the p-GaN/i-InGaN SPSL structure as LQB is beneficial to increasing the hole injection efficiency and decreasing the electron current ***,the radiative recombination and optical power are enhanced.

关键词： GaN-based light-emitting diodes hole injection efficiency droop superlattice(SL)

The circFASN/miR-33a pathway participates in tacrolimusinduced dysregulation of hepatic triglyceride homeostasis

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Signal Transduction and Targeted Therapy 2020年第1期5卷 2132-2141页

作者： Chenzhi Zhang Kangchen Chen Rongli Wei guanghan fan Xuechun Cai Li Xu Beini Cen Jianguo Wang Haiyang Xie Shusen Zheng Xiao Xu Division of Hepatobiliary and Pancreatic Surgery Department of SurgeryFirst Affiliated HospitalZhejiang University School of MedicineHangzhou 310000China Key Lab of Combined Multi-Organ Transplantation Ministry of Public HealthHangzhou 310000China Department of Hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalHangzhou 310000China

Dyslipidemia exhibits a high incidence after liver transplantation,in which tacrolimus,a widely used immunosuppressant,plays a fundamental *** and related circRNAs represent a class of noncoding RNAs that have been recognized as important regulators of genes associated with lipid ***,their transcriptional activities and functional mechanisms in tacrolimus-related dyslipidemia remain *** this study,we observed that tacrolimus could induce triglyceride accumulation in hepatocytes by stimulating sterol response element-binding proteins(SREBPs)and *** in silico and experimental analyses identified miR-33a as a direct target of *** could downregulate circFASN and result in elevated miR-33a in vivo and in *** of circFASN or silencing of miR-33a decreased the promoting effects of tacrolimus on triglyceride ***,the incidence of dyslipidemia in liver transplant recipients with elevated serum miR-33a after liver transplantation was higher than that in patients without elevated serum miR-33a(46.3%vs.18.8%p=0.012,n=73).Our results showed that the circFASN/miR-33a regulatory system plays a distinct role in tacrolimus-induced disruption of lipid ***-33a is likely a risk factor for tacrolimus-related dyslipidemia,providing a potential therapeutic target to combat tacrolimus-induced dyslipidemia after liver transplantation.

关键词： tacrolimus homeostasis elevated

Advantage of dual wavelength light-emitting diodes with dip-shaped quantum wells

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Chinese Science Bulletin 2012年第20期57卷 2562-2566页

作者： XU YiQin fan guanghan ZHOU DeTao LI Xin LU TaiPing ZHAO fang ZHANG YunYan ZHENG ShuWen GONG ChangChun Institute of Opto-Electronic Materials and Technology South China Normal UniversityGuangzhou 510631China

Dual-wavelength light-emitting diodes (DW-LEDs) with dip-shaped quantum wells have been studied by numerical *** emission spectra,light output power,carrier concentration in the quantum wells and internal quantum efficiency are *** simulation results indicate that the DW-LEDs with dip-shaped quantum wells perform better than conventional LEDs with rectangular quantum wells in terms of light output power,leakage current and efficiency *** improvements in the electrical and optical characteristics are mainly attributed to the alleviation of the electrostatic field in the dip-shaped quantum wells.

关键词：发光二极管量子阱双波长光输出功率优势载流子浓度数值模拟发射光谱

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GaN半导体材料的电学性质与光学性质分析

太阳能学报 2008年第6期29卷 662-665页

作者：董少光范广涵华南师范大学光电子材料与技术研究所广州510631 佛山科学技术学院光电子与物理学系佛山528000

用局部旋转密度近似的方法研究GaN材料的电学性质与光学性质,用Cr跃迁金属替代GaN半导体中的N原子,其原子浓度为1.56%。这种材料用孤立和部分填充的中间带表征,是高效太阳电池的候选材料。对中间带的轨道成分进行分析表明,中间带主要由... 详细信息

用局部旋转密度近似的方法研究GaN材料的电学性质与光学性质,用Cr跃迁金属替代GaN半导体中的N原子,其原子浓度为1.56%。这种材料用孤立和部分填充的中间带表征,是高效太阳电池的候选材料。对中间带的轨道成分进行分析表明,中间带主要由跃迁金属的t-群轨道构成。吸收系数的理论计算结果表明,半导体材料的次带吸收会导致太阳能转换效率的增加。

关键词：中间带 GaN 电学性质光学性质半导体材料

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产学研相结合建设LED研发实验室

实验技术与管理 2009年第11期26卷 154-156,159页

作者：张涛范广涵华南师范大学光电子材料与技术研究所

从建设LED（light emitting diode,发光二级管）研发实验室的实践出发,总结了华南师范大学以产学研相结合建设LED研发实验室的思路、目标、管理体制、运行机制与取得的成效。

关键词： LED研发实验室建设实践

生长周期对有机金属化学气相沉积法制备SiO_2-InP光子晶体的影响

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光学学报 2007年第3期27卷 482-486页

作者：谭春华黄旭光范广涵华南师范大学信息光电子科技学院光子信息技术广东省高校重点实验室广州510631 华南师范大学信息光电子科技学院光电子材料与技术研究所广州510631

有机金属化学气相沉积(MOCVD)方法在人工蛋白石空隙中填充了磷化铟(InP)晶体以改变这类材料的光学行为,在选择了InP的生长条件的基础上进行了周期生长试验。利用扫描电子显微镜(SEM)和紫外可见光谱(UV-Vis)对人工蛋白石晶体及其填充InP... 详细信息

有机金属化学气相沉积(MOCVD)方法在人工蛋白石空隙中填充了磷化铟(InP)晶体以改变这类材料的光学行为,在选择了InP的生长条件的基础上进行了周期生长试验。利用扫描电子显微镜(SEM)和紫外可见光谱(UV-Vis)对人工蛋白石晶体及其填充InP后的形貌和反射谱特性进行了分析。结果发现,采用周期生长方式有利于InP在模板空隙中的填充,且在反应时间相同的条件下,反应周期数越多,InP在空隙中的填充率越高,填充率增加反过来增大了二氧化硅球和空隙之间的折射率差,从而可控地对所制备光子晶体光子带隙进行调制。实验表明InP具有较好的生长质量,此项研究为制备三维InP光子晶体打下了基础。

关键词：光学材料光子晶体人工蛋白石有机金属化学气相沉积光子带隙

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淀粉复合膜的制备、性能及应用研究进展

材料导报 2022年第21期36卷 210-219页

作者：王健蓉张强范桄晗杨新斌曾仁权西南大学动物医学院重庆402460 西南大学动物科学技术学院重庆402460 西南大学荣昌校区基础部重庆402460

生物经济正在加速改变食品、环境、医疗和能源等行业,这引起了工商业、学术界和政府的高度关注,因此对天然高分子等生物资源的研究、开发和利用意义重大。天然淀粉因具有来源广泛、价格低廉、无毒、无免疫原、可生物降解和再生、黏附性... 详细信息

生物经济正在加速改变食品、环境、医疗和能源等行业,这引起了工商业、学术界和政府的高度关注,因此对天然高分子等生物资源的研究、开发和利用意义重大。天然淀粉因具有来源广泛、价格低廉、无毒、无免疫原、可生物降解和再生、黏附性和生物相容性良好等优点而倍受青睐,但单淀粉膜却有耐水性差、强度低等缺陷,通过化学键和分子间作用力与其它材料复合可改善其性能。本文综述了用纤维素、壳聚糖、蛋白质、脂肪族聚酯、聚乙烯醇、聚烯烃塑料、纳米氧化物、黏土、磷(膦)酸锆和纤维等改性淀粉,通过溶剂浇铸、压塑、挤出吹塑和注塑成型等制备复合膜,总结了这些复合膜的耐水性、力学性能、生物降解性、水蒸气透过性、热稳定性、相容性和抗菌性及其在食品包装、环境和生物医药等领域的应用。最后,展望了超临界流体、超声活化等技术处理改性后的淀粉有利于膜性能的改善;生物相容性良好的新型插层材料是未来的研究方向。

关键词：淀粉复合膜溶剂浇铸耐水性力学性能

应用不对称一维光子晶体结构制备窄光谱LED

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光学学报 2005年第3期25卷 408-411页

作者：王浩廖长俊范广涵刘颂豪华南师范大学信息光电子学院广州510631

对周期性的GaAlAs/AlAs模块堆积组成的有缺陷的一维光子晶体的光波传输模式进行了理论与实验研究。由于堆积结构的周期性受到破坏,导致了光子晶体中模密度发生变化,光波的传播也发生了变化。对模密度和光的传播模式分别用流行的光子能... 详细信息

对周期性的GaAlAs/AlAs模块堆积组成的有缺陷的一维光子晶体的光波传输模式进行了理论与实验研究。由于堆积结构的周期性受到破坏,导致了光子晶体中模密度发生变化,光波的传播也发生了变化。对模密度和光的传播模式分别用流行的光子能态理论和光学传输矩阵进行了计算和模拟。计算发现采用不对称结构的一维光子晶体结构在实际应用中有更大的灵活性。用金属有机物化学汽相沉积方法实现一维光子晶体,并用于裁剪普通的发光二极管电致发光谱,在20 mA的激发电流下,半峰全宽为2.8 nm,单色性优于共振腔发光二极管。在较大的激发电流下,带边发射的增强现象也被观测到。

关键词：光电子学一维光子晶体光子禁带裁剪模密度