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Jaffe-Campanacci syndrome resulted in amputation: A case report

World Journal of Clinical Cases 2024年第10期12卷 1785-1792页

作者： jun Jiang Min liu Department of Pediatric Surgery West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Jaffe-Campanacci syndrome(JCS)is a very rare *** treatment of JCS is more conservative,and most authors recommend that no surgery should be done in asymptomatic *** conventional concept holds that the natural course of non-ossifying fibromas(NOFs)grows with the development of bones,and the osteolytic region gradually stops expanding and self-healing through bone ossifying around the lesion and ossification within the *** in this case,the bone lesions were potentially biologically aggressive,which led to severe limb deformities and *** SUMMARY We present the case of a 5-year-old girl with JCS presenting with not only NOF sand café-au-lait macules,but also showed features not mentioned before,severe limb pain,and at last resulted in *** was admitted to our hospital after presenting with claudication and mild pain over her right thigh,which worsened when stretching or being *** examination revealed multiple café-au-lait macules on the neck,arm,axilla,and torso,including the nipples and *** revealed multiple lytic lesions in the proximal part of the right humerus,distal part of the right clavicle,proximal and distal parts of the right femur,and proximal parts of the right tibia and *** and biopsy were performed on the distal part of the right *** the age of 7,the girl was re-admitted to our hospital for a pathological fracture in the middle in the right femur and underwent Intralesional excision,internal fixation,bone grafting,and spica *** the age of 10,the girl came to our hospital again for severe pain of the right *** from the middle level of the right femur was *** present the case of a 5-year-old girl with JCS presenting with not only NOFs and café-au-lait macules,but also showed features not mentioned before,severe limb pain,and at last resulted in *** was admitted to our hospital after presenting with claudication and mild pain o

关键词： Jaffe-Campanacci syndrome Multiple non-ossifying fibromas Café-au-lait macule Amputation Case report

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Metamorphic P-T conditions and ages of garnet-biotite schists in the Dahongshan Group from the southwestern Yangtze Block

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Acta Geochimica 2024年第4期43卷 707-718页

作者： jun-xiao Ma guang-shu Yang Yong-feng Yan Xiao-Fei Xu Yun-hua Ren Hui Zhao Xiao-jun Zheng Yuan Qin Faculty of Land Resources Engineering Kunming University of Science and TechnologyKunming 650093China Geological Team 306 of Yunnan Non-Ferrous Metals Geological Bureau Kunming 650217China Yunnan Provincial Bureau of Non-Ferrous Geology Kunming 650051China

The Dahongshan Group,situated at the southwestern margin of the Yangtze Block,represents a geological unit characterized by relatively high-grade metamorphism in the *** paper investigates the garnet-biotite schist from the Laochanghe Formation of the Dahongshan Group,employing an integrated approach that includes petrological analysis,phase equilibrium modeling,and zircon U-Pb *** schist is mainly composed of garnet,biotite,plagioclase,quartz,rutile,and *** equilibrium modeling revealed the peak metamorphic conditions of 8-9 kbar and 635-675°*** further integrating the prograde metamorphic profile of garnet and geothermobarometric results,a clockwise P-T metamorphic evolution path is constructed,which includes an increase in temperature and pressure during the prograde ***-ICP-MS zircon U-Pb dating and zircon Ti thermometry constrains the post-peak metamorphic age of 831.2±7.2 *** with previously reported results,it is revealed that the southwestern margin of the Yangtze Block experienced a large-scale regional metamorphism during the Neoproterozoic(890-750 Ma),which is related to the collisional orogenic *** may be associated with the late-stage assembly of the Rodinia supercontinent or with local compression and subduction processes during the breakup of the Rodinia supercontinent.

关键词： Southwestern Yangtze Block Dahongshan Group Phase equilibrium modeling Zircon U-Pb dating Neoproterozoic metamorphism

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Two-layer Lagrange-based relay network topology and trajectory design for solar system explorations

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Science China(Information Sciences) 2024年第6期67卷 342-358页

作者： jun CAO Jian JIAO Hao liu Rongxing LU Qinyu ZHANG guangdong Provincial Key Laboratory of Aerospace Communication and Networking Technology Harbin Institute of Technology (Shenzhen) Faculty of Computer Science (FCS) University of New Brunswick

Exploration targeting outer planets and even the edge of the solar system is an emerging direction for the deep-space exploration in the next decades. To address this challenge, a novel two-layer Lagrangebased relay network topology is proposed in this study. Specifically, we utilize the Sun-Mars and Sun-Saturn Lagrange points(LPs) L4 and L5 to build a two-layer backbone relay network, which ensures continuous and high-efficiency communication capability for the exploration of the solar system. Furthermore, we utilize the planetary gravity assist and design the transfer trajectory of backbone relays with the help of planetary celestial body motion equations and Kepler's laws. Moreover, we conduct link budget analysis for multihop relay transmission under Gamma-Gamma distribution, shadowed Rician fading, and additive white Gaussian noise channels in several typical exploration scenarios and validate that the LP relays can effectively support future deep-space exploration missions.

关键词： deep-space communication Lagrangian points backbone relay network transfer trajectory relay selection

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Transient state analysis of a rub-impact rotor system during maneuvering flight

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Chinese Journal of Aeronautics 2024年第7期37卷 236-251页

作者： jun WANG Yunfei liu Zhaoye QIN Liang MA Fulei CHU Beijing Key Laboratory of Health Monitoring and Self-Recovery for High-End Machinery Equipment Beijing University of Chemical TechnologyBeijing 100029China State Key Laboratory of Tribology Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China College of Aeronautical Engineering Civil Aviation University of ChinaTianjin 300300China

Maneuvering flight substantially affects the dynamic behavior of rotors;particularly,such flight may cause rubbing between a rotor and stator,which is one of the most serious damages in aircraft *** this paper,a nonlinear dynamic model for describing the dynamic characteristics of a rub-impact rotor system during maneuvering flight is established based on the Lagrange ***,numerical simulations employing the Newmark method are performed,delving into the detailed discussion of the influence of parameters such as rotational speed and maneuvering flight on the transient and steady-state responses of the rotor *** effect mechanism of maneuver load and its coupling with rub impact is *** results show that the impact response induced by maneuvering flight is more obvious in the subcritical state than in the supercritical *** additional stiffness and damping are also induced;in particular,the additional damping has a coupling ***,the rub impact imposes an additional constraint on the rotor system,thereby weakening the influence of the maneuver load and becoming the major factor that determines the dynamic behavior of the rotor system at high speeds.

关键词： Maneuvering flight Rub impact Rotor system Dynamic response Impact response

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What is the Role of Gravity,Turbulence and Magnetic Fields in High-mass Star Formation Clouds?

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Research in Astronomy and Astrophysics 2024年第6期24卷 21-27页

作者： An-Xu Luo Hong-Li liu guang-Xing Li Sirong Pan Dong-Ting Yang School of Physics and Astronomy Yunnan UniversityKunming 650091China South-Western Institute for Astronomy Research Yunnan UniversityKunming 650500China

To explore the potential role of gravity,turbulence and magnetic fields in high-mass star formation in molecular clouds,this study revisits the velocity dispersion–size(σ–L)and density–size(ρ–L)scalings and the associated turbulent energy spectrum using an extensive data *** sample includes various hierarchical density structures in high-mass star formation clouds,across scales of 0.01–100 *** observeσ∝L^(0.26)andρ∝L^(-1.54)scalings,converging toward a virial equilibrium state.A nearly flat virial parameter–mass(α_(vir)-M)distribution is seen across all density scales,withα_(vir)values centered around unity,suggesting a global equilibrium maintained by the interplay between gravity and turbulence across multiple *** turbulent energy spectrum(E(k))analysis,based on theσ–L andρ–L scalings,yields a characteristic E(k)∝k^(-1.52).These findings indicate the potential significance of gravity,turbulence,and possibly magnetic fields in regulating dynamics of molecular clouds and high-mass star formation therein.

关键词： ISM:clouds stars:formation stars:kinematics and dynamics

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Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis:Focus on underlying mechanisms and future perspectives

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Chinese Chemical Letters 2024年第2期35卷 118-130页

作者： Zihan liu Han liu Jialing Cheng Hongliang Wang Yanfang Yang jun Ye Yuling liu State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing 100050China Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation Institute of Materia MedicaChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing 100050China

Ulcerative colitis(UC)is a common progressive inflammatory disease whose incidence has increased rapidly in recent years,and can develop into colorectal cancer in severe *** are currently no adequate or effective treatments for UC due to the fact that some patients have found suboptimal results after repeated administration,while others have experienced adverse *** the rapid development of nanotechnology,developing innovative colon-targeting platforms is essential to improving efficacy,reducing side effects,and improving patient *** this review,we summarize the pathophysiological characteristics of UC and the most recent status of numerous nanodrug delivery systems based on different targeting mechanisms in treating ***,intravenous,and rectal drug delivery nanoparticles targeting the colon are discussed,which can provide ideas for the design of colon-targeting nanoparticles for the treatment of colon diseases,especially for the treatment of *** but not least,we provide a glimpse into the future of colon-targeted delivery systems,as well as future advancements in the field.

关键词： Ulcerative colitis Physiological characteristics Colon-specific drug delivery Mechanisms of action Targeted therapy of UC

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Relationship Between Short-chain Fatty Acids and Parkinson’s Disease:A Review from Pathology to Clinic

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Neuroscience Bulletin 2024年第4期40卷 500-516页

作者： Wen-Xiang Duan Fen Wang jun-Yi liu Chun-Feng liu Department of Neurology and Clinical Research Center of Neurological Disease The Second Affiliated Hospital of Soochow UniversitySuzhou215004China Department of Neurology Dushu Lake Hospital affiliated to Soochow UniversitySuzhou215125China Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience Soochow UniversitySuzhou215123China

Parkinson’s disease(PD)is a complicated neurodegenerative disease,characterized by the accumulation ofα-synuclein(α-syn)in Lewy bodies and neurites,and massive loss of midbrain dopamine *** evidence suggests that gut microbiota and microbial metabolites are involved in the development of *** these,short-chain fatty acids(SCFAs),the most abundant microbial metabolites,have been proven to play a key role in brain-gut *** this review,we analyze the role of SCFAs in the pathology of PD from multiple dimensions and summarize the alterations of SCFAs in PD patients as well as their correlation with motor and non-motor *** research should focus on further elucidating the role of SCFAs in neuroinflammation,as well as developing novel strategies employing SCFAs and their derivatives to treat PD.

关键词： Parkinson’s disease Short-chain fatty acids Microbial metabolites Brain-gut-microbiota axis

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Risk Assessment of Deep-Water Horizontal X-Tree Installation

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China Ocean Engineering 2024年第2期38卷 210-220页

作者： MENG Wen-bo FU guang-ming HUANG Yi liu Shu-jie HUANG Liang GAOYong-hai CNOOC China Limited Zhanjiang BranchZhanjiang 524057China Key Laboratory of Unconventional Oil and Gas Development Ministry of Education(China University of Petroleum(East China))Qingdao 266580China

Due to the high potential risk and many influencing factors of subsea horizontal X-tree installation,to guarantee the successful completion of sea trials of domestic subsea horizontal X-trees,this paper established a modular risk evaluation model based on a fuzzy fault ***,through the analysis of the main process oftree down and combining the Offshore&Onshore Reliability Data(OREDA)failure statistics and the operation procedure and the data provided by the job,the fault tree model of risk analysis of the tree down installation was ***,by introducing the natural language of expert comprehensive evaluation and combining fuzzy principles,quantitative analysis was carried out,and the fuzzy number was used to calculate the failure probability of a basic event and the occurrence probability of a top ***,through a sensitivity analysis of basic events,the basic events of top events significantly affected were determined,and risk control and prevention measures for the corresponding high-risk factors were proposed for subsea horizontal X-tree down installation.

关键词： subsea horizontal X-tree risk assessment fuzzy fault tree modular risk evaluation model

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BaCe_(0.8)Fe_(0.1)Ni_(0.1)O_(3−δ)-impregnated Ni-GDC by phase-inversion as an anode of solid oxide fuel cells with on-cell dry methane reforming

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Journal of Advanced Ceramics 2024年第6期13卷 834-841页

作者： Yanya liu jun Luo Cheng Li Bo liu Dong Yan Jian Li Lichao Jia School of Materials Science and Engineering State Key Laboratory of Materials Processing and Die&Mould TechnologyHuazhong University of Science and TechnologyWuhan 430074China

BaCe_(0.8)Fe_(0.1)Ni_(0.1)O_(3−δ)(BCFN)in a perovskite structure is impregnated consecutively by BCFN solution and BCFN suspension into a phase-inversion prepared NiO–Gd_(0.1)Ce_(0.9)O_(2−δ)(GDC)scaffold as an anode for solid oxide fuel cells(SOFCs)with on-cell dry reforming of methane(DRM).The whole pore surface of the scaffold is covered by small BCFN particles formed by BCFN solution impregnation;the large pores near the scaffold surface are filled by BCFN aerogels with a high specific surface area produced by BCFN suspension impregnation,which act as a catalytic layer for on-cell *** reduction,the anode consists of a Ni–GDC scaffold and BCFN particles with exsolved FeNi3 *** BCFN-impregnated Ni–GDC anode has higher electrical conductivity,electrochemical activity,and resistance to carbon deposition,with which the cell shows maximum power densities between 1.44 and 0.92 W·cm^(−2) when using H_(2) and between 1.09 and 0.50 W·cm^(−2) when using CO_(2)–CH_(4) at temperatures ranging from 750 to 600℃.A stable performance at 400 mA·cm^(−2) and 700℃is achieved using 45%CO_(2)–45%CH_(4)–10%N_(2) for more than 400 h without carbon deposition,benefiting from the impregnated BCFN aerogel with a high specific surface area and water adsorbability.

关键词： aerogel solid oxide fuel cells(SOFCs) phase-inversion dry reforming of methane(DRM) carbon resistance

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Unraveling role of double-exchange interaction in electrochemical water oxidation by external magnetic field

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Rare Metals 2024年第1期43卷 289-297页

作者： jun Li jun-Ming Li Hong Hong Dong-Xue liu Qing-Qi Cao Dun-Hui Wang National Laboratory of Solid State Microstructures and Jiangsu Provincial Key Laboratory for Nanotechnology Nanjing UniversityNanjing 210093China School of Electronics and Information Hangzhou Dianzi UniversityHangzhou 310018China

Double-exchange(DE) interaction plays an important role in electrocatalytic oxygen evolution reaction(OER).However,precise achievement of DE interaction often requires foreign dopants or vacancy engineering,leading to destabilization of the catalysts and deterioration of *** contrast,the utilization of environmentally friendly,contactless,and continuously adjustable magnetic fields to study the OER process is profitable to avoid aforementioned interference factors and further elucidate the direct relationship_(0.5)between DE interaction and OER ***,by using cobalt hydroxide carbonate(Co(OH)(CO_(3))·xH_(2)O,CoHC) nanostructures as a proof-of-concept study,external magnetic fields are carefully implemented to verify the role of DE interaction during water oxidation *** studies reveal that external magnetic fields effectively enhance the reaction rate of the catalyst,the overpotential decreases from 386 to 355 mV(100 mA·cm^(-2)),while Tafel slopes drastically decline from 93 to 67 mV·dec^(-1)(1.0 T).Moreover,magnetic field increment exhibits robust *** in situ Raman and impedance measurements under external field,it can be found that magnetic field promotes the electron migration between Co^(2+) and Co^(3+) in the CoHC catalysts with the assistance of DE interactions,thus boosting the OER efficiency.

关键词： Magnetic field Double-exchange(DE)interaction Electrocatalysis Oxygen evolution reaction(OER) Cobalt hydroxide carbonate

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