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Characterization of a Novel Chlorophyll-Deficient Mutant Mt6172 in Wheat

Journal of Integrative Agriculture 2012年第6期11卷 888-897页

作者： guO Hui-jun ZHAO Hong-bing ZHAO Lin-shu gu jia-yu ZHAO Shi-rong LI Jun-hui LIU Qing-chang LIU Lu-xiang Key Laboratory of Crop Genomics and Genetic Improvement Ministry of Agriculture/Beo'ing Key Laboratory of Crop Genetic Improvement China Agricultural University Beijing 100193 P.R.China National Key Facility for Crop Gene Resources and Genetic Improvement Institute of Crop Sciences Chinese Academy of Agricultural Sciences Beijing 100081 P.R. China

Identification of new chlorophyll-deficient mutants will provide materials for studying signaling components and pathways between plastid and nucleus. A novel chlorophyll-deficient mutant, named Mt6172, was obtained by spaceflight environment induction. Genetic analysis showed that its inheritance was controlled by nuclear and cytoplamic genes. Leaf color of its self-fertilized progenies was albino, narrow-white striped, or green. Only a few cells with abnormal chloroplasts were observed in albino plants and white section of narrow-white striped plants. These chloroplasts had obvious flaws in inner structure, and granum lamellae was extremely disordered. The narrow-white striped plants were characterized with green- and-narrow-white striped leaves, and the width of stripes between different plants was even, their plant height, number of productive tillers, and 1 000-grain weight were lower than those of the wild type. The narrow-white striped plants and the wild type had significant difference in the value of potential activity of photosystem II at all tested stages. At elongation stage, which was impacted the most seriously, effective quantum yield significantly decreased, whereas the energy for photoprotection and photodamage significantly increased. changes of electron transport rate, photochemical dissipation, Under different photosynthetic active radiation conditions, and effective quantum yield were different, electron transport rate was more impacted than other parameters. Therefore, the leaf morphology and inheritance of mutant Mt6172 was different from the other reported mutants in wheat, and it was a novel mutant of chloroDhvll deficiency.

关键词： Triticum aestivum L. space mutagenesis chlorophyll-deficient mutant agronomic traits chloroplastultrastructure

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Inherited Genetic Susceptibility to Nonimmunosuppressed Epstein-Barr Virus-associated T/NK-cell Lymphoproliferative Diseases in Chinese Patients

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Current Medical Science 2021年第3期41卷 482-490页

作者： Yu-qi guAN Ke-feng SHEN Li YANG Hao-dong CAI Mei-lan ZHANG jia-chen WANG Xiao-lu LONG Jie XIONG jia gu Pei-ling ZHANG Min XIAO Wei ZHANG jian-feng ZHOU Department of Hematology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Epstein-Barr virus(EBV)T/NK-cell lymphoproliferative diseases are characterized by clonal expansion of EBV-infected T or NK cells,including chronic active EBV infection of T/NK-cell type(CAEBVT/NK),EBV-associated hemophagocytic lymphohistiocytosis(EBV HLH),extranodal NK/T-cell lymphoma of nasal type(ENKTL),and aggressive NK-cell leukemia(ANKL).However,the role of inherited genetic variants to EBV+T/NK-LPDs susceptibility is still unknown.A total of 171 nonimmunosuppressed patients with EBV T/NK-LPDs and 104 healthy donors were retrospectively collected and a targeted sequencing study covering 15 genes associated with lymphocyte cytotoxicity was *** 94 gene variants,mostly located in UNCI 3D,LYST,ITK,and PRF1 genes were detected,and mutations covered 28/50(56.00%)of CAEBV-T/NK,31/51(60.78%)of EBV HLH,13/28(46.42%)of ENKTL,and 13/48(27.09%)of *** mutations represented monoallelic and ***-year overall survival rate of patients with CAEBV-T/NK and EBV+HLH was significantly lower in patients with germline mutations than in those without germline mutations(P=0.0284,P=0.0137).Our study provided novel insights into understanding a spectrum of nonimmunosuppressed EBV*T/NK-LPDs with respect to genetic defects associated with lymphocyte cytotoxicity and reminded us that the gene sequencing may be an auxiliary test for diagnosis and risk stratification of EBV+T/NK-LPDs.

关键词： germline mutation EBV-associated T/NK-cell lymphoproliferative disease hemophagocytic lymphohistiocytosis primary immunodeficiencies lymphocyte cytotoxicity gene sequencing

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Effect of Morphology for Novel Bainite/Martensite Dual-Phase High Strength Steel on Its Hydrogen Embrittlement Susceptibility

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Journal of Iron and Steel Research International 2001年第1期8卷 37-40页

作者： CHANG Kai-di gu jia-lin FANG Hong-sheng BAI Bing-zhe ZHANG Wen-zheng YANG Zhi-gang LIU Dong-yu ZHANG Chi Tsinghua University

With TEM、SEM, various high temperature deformed structures in W9Mo3Cr4V steel were investigated. The sub structures,recrystallized nuclei, as well as the dynamic precipitation were also studied and analyzed. The relationship between recrystallized structures and dynamic precipitation was discussed. The results showed that the deformed structures in W9Mo3Cr4V steel are more complicated than those in low alloy steels. Because W9Mo3Cr4V steel is a high speed steel, there are a large number of residual carbides on the matrix. Also, much dynamic precipitating carbides will precipitate during deformation at high temperature.

关键词： W9Mo3Cr4V steel high temperature deformed structure dynamic precipitation

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Studies of TLP Dynamic Response Under Wind, Waves and Current

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China Ocean Engineering 2012年第3期26卷 363-378页

作者：谷家扬杨建民吕海宁 State Key Laboratory of Ocean Engineering Shanghai Jiao Tong University School of Naval Architecture and Marine Engineering Jiangsu University of Science and Technology

Investigated is the coupled response of a tension leg platform （TLP） for random waves. Inferred are the mass matrix, coupling stiffness matrix, damping matrix in the vibration differential equation and external load of TLP in moving coordinating system. Infinitesimal method is applied to divide columns and pontoons into small parts. Time domain motion equation is solved by Runge-Kutta integration scheme. Jonswap spectrum is simulated in the random wave, current is simulated by linear interpolation, and NPD spectrum is applied as wind spectrum. The Monte Carlo method is used to simulate random waves and fluctuated wind. Coupling dynamic response, change of tendon tension and riser tension in different sea conditions are analyzed by power spectral density （PSD）. The influence of approach angle on dynamic response of TLP and tendon tension is compared.

关键词： TLP nonlinear stochastic waves sea state different approach angles coupling with wave current and wind

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Robert Frost:A Poet Who Had a Lover's Quarrel with the World

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海外英语 2018年第11期 172-174页

作者：顾佳 Department of the Applied Foreign Languages Henan Industry and Trade Vocational CollegeZhengzhou 450000China

Rober Frost, as one of American 20^(th) century leading poets, demostrates his paradoxical and contradictory views in his poetry——love and complaint. The paper proves that the lover's quarrel is an important theme in his peotry by analyzing Robert's love and quarrel with the world from three aspects in respect to his personal experience and social background in his age.

关键词： Robert Frost lover’s quarrel paradox conflct poetry

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An Analysis on Women's Relationship in The House of Mirth

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海外英语 2018年第10期 164-166页

作者：顾佳 Department of the Applied Foreign Languages Henan Industry and Trade Vocational College

In The House of Mirth,written by Edith Wharton,most of feminist critics emphasize the awakening process of Lily’s selfconsciousness and women’s suffering in that patriarchal *** from them,the paper attempts to equally focus on the other female characters in the novel and regard the relations between them as a whole in order to reveal that most of women,especially those from the upper-class,still fail to recognize the necessity of unity,and it’s still a long way for them to go until reach the final success.

关键词： Edith Wharton House of Mirth women’s relationship

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Bidirectional crosstalk between therapeutic cancer vaccines and the tumor microenvironment:Beyond tumor antigens

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Fundamental Research 2023年第6期3卷 1005-1024页

作者： Si-Wei Zhang Han Wang Xiao-Hong Ding Yu-Ling Xiao Zhi-Ming Shao Chao You Ya-jia gu Yi-Zhou jiang Key Laboratory of Breast Cancer in Shanghai Department of Breast SurgeryFudan University Shanghai Cancer CenterShanghai 200032China Department of Radiology Fudan University Shanghai Cancer Center270 Dong’an RoadShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China

Immunotherapy has rejuvenated cancer therapy,especially after anti-PD-(L)1 came onto the *** the many therapeutic options,therapeutic cancer vaccines are one of the most essential *** great progress has been made in research on tumor antigen vaccines,few phase III trials have shown clinical *** of the reasons lies in obstruction from the tumor microenvironment(TME).Meanwhile,the therapeutic cancer vaccine reshapes the TME in an ambivalent way,leading to immune stimulation or immune *** this review,we summarize recent progress on the interaction between therapeutic cancer vaccines and the *** respect to vaccine resistance,innate immunosuppressive TME components and acquired resistance caused by vaccination are both *** the underlying mechanism of this crosstalk provides insight into the treatment of cancer by directly targeting the TME or synergizing with other therapeutics.

关键词： Therapeutic cancer vaccine Tumor microenvironment Acquired resistance Immunosupportive Immunosuppressive

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从小城镇建设到跨区域协作发展——费孝通应用人类学的学术实践及其思想脉络

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中南民族大学学报（人文社会科学版） 2020年第2期40卷 35-41页

作者：谷家荣云南师范大学哲学与政法学院云南昆明650500

小城镇研究是费孝通在获得“第二次学术生命”之后开辟出的一个重要研究领域,也是其将人类学田野调查与政策咨询紧密结合的典型研究模式,是中国应用人类学政策应用的典范。基于对1981-1995年间费孝通先生的143封亲笔信的梳理,结合相关研... 详细信息

小城镇研究是费孝通在获得“第二次学术生命”之后开辟出的一个重要研究领域,也是其将人类学田野调查与政策咨询紧密结合的典型研究模式,是中国应用人类学政策应用的典范。基于对1981-1995年间费孝通先生的143封亲笔信的梳理,结合相关研究,分析了费孝通小城镇研究发展的缘由、分阶段描述了其建设小城镇的学术思想及其延伸的历史脉络。面对中国人口暴涨及城乡发展差距困境,费孝通把自己的关注视点聚焦到小城镇,试图通过小城镇的调研,使其成为带动农村经济和截住农村人口流入大城市的“蓄水池”。十多年间,从江苏省开始,走访了除西藏和台湾两地之外的中国所有省区。为“搞活人口这盘棋”乃至“下活全国一盘棋”贡献了无穷智慧。费孝通的小城镇研究思想为推进社会学中国本土化和中国城乡社会协调发展发挥了重要作用。

关键词：学科史小城镇建设费孝通学术思想应用人类学

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滇边跨境民族研究六十年的回顾与前瞻

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学术探索 2010年第4期 85-91页

作者：谷家荣云南大学西南边疆少数民族研究中心云南昆明650091

滇边实践的流变和国家建设的转变影响着滇边跨境民族研究的叙事范式。建国初探重在清晰滇边跨境民族模糊的面相。二十世纪六七十年代紧张的国家关系使跨境民族研究集中转向北部疆域,滇边跨境民族研究涅无新的推进。直至八十年代,国家守... 详细信息

滇边实践的流变和国家建设的转变影响着滇边跨境民族研究的叙事范式。建国初探重在清晰滇边跨境民族模糊的面相。二十世纪六七十年代紧张的国家关系使跨境民族研究集中转向北部疆域,滇边跨境民族研究涅无新的推进。直至八十年代,国家守土固疆和富边强国的意志延伸到全国边境,跨境民族研究为现实服务的理念成为急迫的国家需要,滇边跨境民族研究才再度得以补课建基。研究雏形的丰腴和完善,又将滇边跨境民族研究带入了争鸣的斡旋。这些争辩的话语使许多云南本土的边疆学研究者回头静心关怀实证,从滇边跨境民族真实的生境来哲思,发现了更多新鲜的研究理路和更加深层的社会问题。

关键词：滇边跨境民族回顾前瞻

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面向风电消纳的考虑热网特性及热舒适度弹性的电热联合优化调度

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电网技术 2019年第10期43卷 3648-3661页

作者：林俐顾嘉王铃新能源电力系统国家重点实验室(华北电力大学) 北京市昌平区102206 广东电网公司电力科学研究院广东省广州市510080

季节性供热需求与大规模风电消纳需求间的矛盾,导致夜间高热负荷时段的弃风问题突出,深度挖掘热网侧与热负荷侧弹性以提高风电上网空间是解决该问题的一个思路。面向具有风电消纳需求的电热联合系统,首先建立考虑延时与热衰减的热网特性... 详细信息

季节性供热需求与大规模风电消纳需求间的矛盾,导致夜间高热负荷时段的弃风问题突出,深度挖掘热网侧与热负荷侧弹性以提高风电上网空间是解决该问题的一个思路。面向具有风电消纳需求的电热联合系统,首先建立考虑延时与热衰减的热网特性;在热负荷侧引入PMV指标表征用户的用热舒适度,确立含热负荷弹性特征的热平衡区间约束。进而以总煤耗量最小,最大限度消纳风电为目标,建立考虑热网特性及热负荷舒适度弹性的电热联合系统优化调度模型,并通过仿真验证其有效性。结果表明,单一考虑热网特性的优化效果与实际风电出力特性有关,具有不确定性;而考虑热负荷舒适度弹性可在全时段赋予系统灵活的弹性调节空间,优化效果显著;考虑上述两特性的协同优化,基本可实现算例系统的风电全额消纳,优化效果最佳。

关键词：风电消纳热网特性热舒适度弹性 PMV 电热联合调度

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