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丛书名：三思文库.科学争鸣系列/刘华杰编

1999年

作者：（美）格雷格·迈尔斯（gregory A.Myers）孙雍君等译

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拜占庭简史

罕见的、类似心内肿块的右冠状动脉巨大血管瘤一例

2019年

作者： (美)蒂莫西·E.格里高利(Timothy E. gregory)

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麻醉与镇痛 2010年第1期6卷 99-100页

作者： Estibaliz Alomar-Melero Tomas D. Martin gregory M. Janelle Yong g. Peng 季璐璐(译) 钱燕宁(校) Division of Cardiothoracic Anesthesia GainesvilleFlorida Department of Surgery Division of Thoracic and Cardiovascular Surgery GainesvilleFlorida Department of Anesthesiologw Division of Cardiovascular Aalesthesiology University of Florida College of Medidne GainesvilleFlorida 不详

患者男性，49岁，因在主动脉弓远心端和降胸主动脉近心端一囊状血管瘤，为明确检查而转诊来院，既往有乔布（Job）氏综合征（高IgE综合征）病史，这是一种以反复感染和结缔组织异常为特征的免疫学疾病。

关键词：巨大血管瘤右冠状动脉高IgE综合征肿块结缔组织异常胸主动脉主动脉弓反复感染

Validation and Comparison of Two Calibration Methods for the Measurement of Stable Iodine in the Urinary Matrix by ICP-MS:Standard Addition *** Calibration

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American Journal of Analytical Chemistry 2017年第4期8卷 245-263页

作者： geraldine Landon Celine Bouvier-Capely Alexandre Legrand Thibaud Sontag gregory Finance Mailie Saint-Hilaire Francois Rebiere Xavier Millot Valerie Renaud-Salis Michelle Agarande Institute for Radiological Protection and Nuclear Safety(IRSN) Fontenay-aux-RosesFrance The French Alternative Energies and Atomic Energy Commission(CEA) Gif-sur-YvetteFrance

Background: In the context of a nuclear reactor accident, thyroid is the main target organ of radioactive iodines. To avoid as much as possible thyroid disorders or even cancer development, it is recommended to administer a single dose of potassium iodide to people at risk of exposure. Nevertheless, the Fukushima Dai-ichi disaster has pointed out many questions about the conditions of stable iodine prophylaxis implementation highlighting the need for reflection further revision of the actual “iodine doctrine”. Therefore, providing useful data is required notably through the implementation of animal experiments to strengthen current knowledge and to edit new recommendations. Methods: Urinary iodine constitutes a very good indicator to investigate the function of thyroid, its interpretation demands reliable analyses. Prior to perform animal experiments, two calibration methods were designed by our lab and compared together (standard addition and external calibration) to assess the urinary concentration of stable iodine in urine by ICP-MS. They were validated based on several key parameters especially linearity, accuracy and limits of detection (LOD) and quantification (LOQ). Results: The results were nicely satisfying. Indeed, both calibration methods have indicated very good coefficients of correlations, accuracies with low expanded relative uncertainties were obtained. The estimated LOD in the sample for standard addition method and external calibration were fully acceptable, 0.39 μg·L-1 and 0.35 μg·L-1, respectively. All performance criteria have been thus fulfilled successfully. The established methods were proven to be accurate, robust and sensitive. Once validated, both calibration methods were applied to rat urine samples and the results of z-score and Wilcoxon W test concluded that there were no statistically significant differences between both methods.

关键词： Stable Iodine Urine Standard Addition External Calibration Validation

卒中治疗学术产业圆桌会议：下一代血管内治疗试验

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国际脑血管病杂志 2017年第9期25卷 782-791页

作者： Tudor g. Jovin gregory W. Albers David S. Liebeskind 徐加平储丹丹张伟王静欧志杰曹勇军 From the Stroke Institute and UPMC Center for Neuroendovascular Therapy Pittsburgh PA Department of Neurology University of Pittsburgh Medical Center PA Department ofNeurology Stroke Center Stanford University School of Medicine Palo AltoCA 苏州大学附属第二医院神经内科 215004

背景和目的卒中治疗学术产业圆桌会议（Stroke Treatnlem Academic Industry Roundtable，STAIR）旨在通过学术界、产业界和监管机构之间的合作来推动急性卒中治疗发展。为了追求这一目标，根据大血管闭塞性卒中血管内治疗（endovascula... 详细信息

背景和目的卒中治疗学术产业圆桌会议（Stroke Treatnlem Academic Industry Roundtable，STAIR）旨在通过学术界、产业界和监管机构之间的合作来推动急性卒中治疗发展。为了追求这一目标，根据大血管闭塞性卒中血管内治疗（endovascular therapy，ET）获益的现有最新I级证据，制定出STAIR第9届会议专家共识推荐意见以概述将来ET领域的研究重点。方法推动该领域发展有3个主要方向：（1）建立在大血管闭塞性卒中患者中实施ET的医疗体系；（2）开发ET的辅助治疗手段；（3）探索ET在近期试验内未经过充分研究的患者人群中的临床获益情况。此外，还对诸如最佳试验设计和转归评价指标之类的方法学问题进行讨论。结果应对医疗体系发展策略进行调整以确保符合ET指征的患者能有机会得到治疗，同时能最大限度地缩短再灌注时间。辅助治疗手段包括神经保护、改善微循环／侧支循环以及围手术期管理。为了扩展适合ET的患者人群范围，将来的研究重点应是确定ET在那些超过传统治疗时间窗的患者、基线梗死核心区较大的患者以及其他重要亚组患者中的获益情况。结论大血管闭塞性卒中ET的研究重点是改进治疗体系、研究有效的辅助治疗手段以及探讨能否扩展ET的治疗指征。

关键词：共识目标微循环再灌注卒中

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Dr. V. K. Ting

地质学报 1940年第Z1期 369-370页

作者： g.W.TYRRELL University of glasgow

V. K. Ting studied geology in the University of glasgow during. theSession 1909-10 and 1910-11, having been attracted to glasgow by the personalityand power of the late Prof. J. W. gregory. He was then 20 or 21 years of

关键词： Dr

CD36 expression and lipid metabolism following an oral glucose challenge in South Asians

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World Journal of Diabetes 2015年第7期6卷 983-989页

作者： Jeetesh V Patel Amitava Banerjee Silvia Montoro-garcia Eduard Shantsila Mushfique Alam Paul Flinders Kathleen AL Houlton Elizabeth A Hughes gregory YH Lip Paramjit S gill University of Birmingham Centre for Cardiovascular Sciences Sandwell and West Birmingham Hospitals NHS Trust Sandwell Medical Research Unit Sandwell General Hospital Primary Care Clinical Sciences University of Birmingham Medical School University of Nottingham

AIM:To investigate lipid metabolism and the relationship with monocyte expression of the fatty acid translocase CD36 in South ***:An observational study of South Asians whom as an ethnic group have-a higher risk of developing *** susceptibility to diabetes is coupled with an earlier and more rapid progression of micro-,and macro-vascular *** healthy South Asian participants [mean age 34.6(8.9) years,76.2% male,mean body-mass index 25.0(5.2) kg/m2] were recruited from an urban residential area of central Birmingham(United Kingdom).The main outcomes measured were post prandial(30 min) and post absorptive(120 min) changes from fasting(0 min) in circulating lipoproteins,lipds and hormones,andmonocyte expression of CD36 post injection of a 75 g oral glucose *** inducements of variations of monocyte CD36 expression were ***:Our results showed evident changes in monocyte CD36 expression following the glucose challenge(P gressively during the challenge(P glyceride) concentrations within very low density lipoprotein(VLDL) and low density lipoprotein subfractions(P glucose,serum triglycerides and high density lipoprotein cholesterol remained largely *** of monocyte CD36 were negatively(r =-0.47,P = 0.04) associated to fat from the diet and positively to carbohydrate from the diet(r = 0.65,P ggest that the initiation of VLDL genesis follows the consumption of glucose within this population,inferring that the sequestration of NEFA from these particles happens due to the increased availability of CD36 *** these are preliminary results,it would appear that lifestyle exposures have a role in moderating the expression of CD36.

关键词： CD36 Lipoprotein glucose South Asians Diabetes Micro-vascular Macro-vascular

Association between Exposure to Metals during Pregnancy,Childhood gut Microbiome,and Risk of Intestinal Inflammation in Late Childhood

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Environment & Health 2024年第10期2卷 739-749页

作者： Vishal Midya Manasi Agrawal Jamil M.Lane Chris gennings Leonid Tarassishin Libni A.Torres-Olascoaga Joseph Eggers Jill K.gregory Mellissa Picker Inga Peter Jeremiah J.Faith Manish Arora Martha M.Tellez-Rojo Robert O.Wright Jean-Frederic Colombel Shoshannah Eggers Department of Environmental Medicine and Climate Science Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Division of gastroenterology Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Center for Molecular Prediction of Inflammatory Bowel Disease(PREDICT) Department of Clinical MedicineAalborg UniversityCopenhagen 9220Denmark Department of genetics and genomic Sciences Icahn School of MedicineNew York 10029-6574New YorkUnited States Center for Research on Nutrition and Health National Institute of Public HealthCuernavaca 62508Mexico Department of Immunology and Immunotherapy Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Department of Epidemiology University of Iowa College of Public HealthIowa City 52242 IowaUnited States Instructional Technology group Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States

Alterations to the gut microbiome and exposure to metals during pregnancy have been suggested to impact inflammatory bowel ***,how prenatal exposure to metals eventually results in long-term effects on the gut microbiome,leading to subclinical intestinal inflammation,particularly during late childhood,has not been *** is also unknown whether such an interactive effect drives a specific subgroup of children toward elevated susceptibility to intestinal *** used an amalgamation of machine-learning techniques with a regression-based framework to explore if children with distinct sets of gut microbes and certain patterns of exposure to metals during pregnancy(metal−microbial clique signature)had a higher likelihood of intestinal inflammation,measured based on fecal calprotectin(FC)in late *** obtained samples from a well-characterized longitudinal birth cohort from Mexico City(n=108),*** the second and third trimesters of pregnancy,11 metals were measured in whole *** microbial abundances and FC were measured in stool samples from children 9−11 years of *** FC was defined as having FC above 100μg/g of *** identified subgroups of children in whom microbial and metal−microbial clique signatures were associated with elevated FC(false discovery rate(FDR)gnatures significantly associated with elevated FC:(1)low cesium(Cs)and copper(Cu)in the third trimester and low relative abundance of Eubacterium ventriosum(OR[95%CI]:10.27[3.57,29.52],FDRgh relative abundances of Roseburia inulinivorans and Ruminococcus torques(OR[95%CI]:7.21[1.81,28.77],FDRgut microbes and specific exposure patterns to metals during pregnancy may have higher fecal calprotectin levels in late childhood,denoting an elevated risk of intestinal inflammation.

关键词： exposome metals machine learning microbiome environmental epidemiology intestinal inflammation

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践行达不成协议的艺术

商业周刊（中文版） 2019年第16期 36-38页

作者： Tim Ross gregory Viscusi Arne Delfs John Follain 李译(译) 不详

●法国总统埃马纽埃尔·马克龙誓言在本次法国g7峰会上实行"创新",但多边主义的时代已然落幕6月29日凌晨两点,曰本大阪,20国集团(g20)峰会谈判室里的官员们开始有人睡着。他们已经连轴转工作了两天,靠虾酱意大利面及其他难吃的无国界融... 详细信息

●法国总统埃马纽埃尔·马克龙誓言在本次法国g7峰会上实行"创新",但多边主义的时代已然落幕6月29日凌晨两点,曰本大阪,20国集团(g20)峰会谈判室里的官员们开始有人睡着。他们已经连轴转工作了两天,靠虾酱意大利面及其他难吃的无国界融合料理果腹。

关键词：艺术协议法国总统 20国集团多边主义意大利峰会官员