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International Understanding 1994年第4期 3-7页

作者： $$$$Li Yining( chinese Association for International Understanding,Professor of beijing university)

Ｃｈｉｎａ＇ｓＥｃｏｎｏｍｉｃＲｅｆｏｒｍＬｉＹｉｎｉｎｇ（Ｖｉｃｅ－ＰｒｅｓｉｄｅｎｔｏｆＣｈｉｎｅｓｅＡｓｓｏｃｉａｔｉｏｎｆｏｒＩｎｔｅｒｎａｔｉｏｎａｌＵｎｄｅｒｓｔａｎｄｉｎｇ，ＰｒｏｆｅｓｓｏｒｏｆＢｅｉ...

Ｃｈｉｎａ＇ｓＥｃｏｎｏｍｉｃＲｅｆｏｒｍＬｉＹｉｎｉｎｇ（Ｖｉｃｅ－ＰｒｅｓｉｄｅｎｔｏｆＣｈｉｎｅｓｅＡｓｓｏｃｉａｔｉｏｎｆｏｒＩｎｔｅｒｎａｔｉｏｎａｌＵｎｄｅｒｓｔａｎｄｉｎｇ，ＰｒｏｆｅｓｓｏｒｏｆＢｅｉｊｉｎｇＵｎｉｖｅｒｓｉｔｙ）１．...

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UNUSUAL FORMATION OF ORGANO-NEODYMIUM AND -SAMARIUM CATIOHS AND X-RAY STRUCTURE OF [(MeOCH_2CH_2C_5H_4 ) _2Sm(thf) ] [Co (CO)_ 4]

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chinese Chemical Letters 1994年第4期5卷 345-348页

作者： Dao Li DENG Xiao Fan CHENG Chang Tao QIAN(Laboratory of Organometallia Chemistry, shanghai Instituteof orgauio Chemistry, chinese academy of sciences, 345 Lingling Lu, shanghai 200032)Xiang Lin JIN(Department of Chemistry, Peking university. beijing 100

The [CP' 2Ln (thf) ] + cation (CP' = MeOCH2CH2C5H4, Ln =Nd 1, Sm 2) has been synthesized by the reaction of Cp'2LnI with KCo (CO) 4. A single-crystal X-ray diffraction study shows that the heterobimetallic complex 2 e... 详细信息

关键词： CH MeOCH2CH2C5H4 thf STRUCTURE Sm AND CO

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热处理对煤焦反应性及微观结构的影响

燃料化学学报 2004年第6期32卷 673-678页

作者：张守玉吕俊复王文选朱廷钰黎永岳光溪清华大学热能工程系热能工程研究所中国科学院过程工程研究所北京100080

用热天平和XRD考察了热处理对二种煤(河北蔚县褐煤、四川湔江烟煤)镜质组半焦微观结构和反应活性的影响。TGA结果表明,热处理温度增加,蔚县煤镜质组(YXV)与湔江煤镜质组(JJV)焦炭的反应性降低;YXV焦炭的反应性随着热处理时间的增加而急... 详细信息

用热天平和XRD考察了热处理对二种煤(河北蔚县褐煤、四川湔江烟煤)镜质组半焦微观结构和反应活性的影响。TGA结果表明,热处理温度增加,蔚县煤镜质组(YXV)与湔江煤镜质组(JJV)焦炭的反应性降低;YXV焦炭的反应性随着热处理时间的增加而急剧下降,但一定热处理时间(60min)后,其下降趋势变缓;热处理时间对JJV焦炭的影响较小。XRD结果表明,在热处理温度为900℃,初焦热处理时间为60min时,YXV焦炭晶格结构发生明显改变,900℃以上,YXV焦炭芳香堆垛高度Lc随着热处理时间的增加而增加;热处理时间对JJV焦炭的影响不如YXV显著,而只有在较高的热处理温度(1200℃)下,碳的微观结构才出现明显的有序化。热处理导致的焦炭微观碳结构趋于有序化是焦炭反应性下降的主要原因。

关键词：煤焦反应活性微观结构热处理

Air-sea heat flux exchange over the South china Sea under different weather conditions before and after southwest monsoon onset in 2000

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Acta Oceanologica Sinica 2003年第3期22卷 369-383页

作者： Junyue Yan, Huadong Yao, Jianglong Li, Zhiyi Tang, Guorong Jiang, Wenyu Sha, Xunqiang Li, Yiguo Xiao National Climate Center, beijing 100081, china. E-mail: yanjy@cma.gov.cnPLA university of Science Technology, Nanjing 211101, china National Climate Center Beijing 100081 China PLA university of Science Technology Nanjing 211101 China

With the data observed from the Second SCS Air-Sea Flux Experiment on the Xisha air-sea flux research tower, the radiation budget, latent, sensible heat fluxes and net oceanic heat budgets were caculated before and after summer monsoon onset. It is discovered that, after summer monsoon onset, there are considerable changes in air-sea fluxes, especially in latent heat fluxes and net oceanic heat budget. Furthermore, the analyzed results of five synoptic stages are compared. And the characteristics of the flux transfer during different stages around onset of South china Sea monsoon are discussed. The flux change shows that there is an oceanic heat accumulating process during the pre-onset and the break period, as same as oceanic heat losing process during the onset period. Moreover, latent fluxes, the water vapor moving to the continent, even the rainfall appearance in chinese Mainland also can be influenced by southwester. Comparing Xisha fluxes with those obtained from the Indian Ocean and the western Pacific Ocean, their differences may be observed. It is the reason why SSTs can keep stable over the South china Sea while they decrease quickly over the Arabian Sea and the Bay of Bengal after monsoon onset.

关键词： South china Sea air-sea heat fluxes South china Sea monsoon

Increased plasma melatonin level and mtDNA copy number and decreased mtDNA damage as biomarkers for greater opiates abstinence

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Increased plasma melatonin level and mtDNA copy number and d...

Brain Dynamic Mechanisms of Scale Effect In Visual Spatial Attention

“细胞活动生命活力”——中国细胞生物学学会全体会员代表大会暨第十二次学术大会

作者： Yue-mei Feng~(1,3),Ling-Yan Su~(1,3),De-Xiang Li~2,Yi-Ping Zhang~2,Yong-Gang Yao~1 1.Key Laboratory of Animal Models and Human Disease Mechanisms of the chinese academy of sciences & Yunnan Province,Kunming Institute of Zoology,Kunming,Yunnan 650223,china 2.Yunnan Police Officer academy,Kunming,Yunnan 650223,china 3.graduate School of the chinese academy of sciences,beijing 100039,china

Drug addiction is a very serious social problem and continues to cause enormous financial costs on society. The available treatments remain to be inadequate for the drug abusers and addiction relapse rates vary depending on the substance being ***,an improved understanding of the biological change during the process of drug abstinence will lead to more effective treatment and eventually to improve the recovery of drug *** studies have demonstrated that the endocrine and metabolism systems were actively involved in this *** is the main secretory product of the pineal gland which is known to affect drug *** also functions as a powerful antioxidant to protect mitochondria and mtDNA from the oxidative damage caused by reactive oxygen species in the central nervous *** hypothesized that the change of plasma melatonin level and alteration of mtDNA in peripheral blood could be used as biomarkers for better drug *** this study,we detected the plasma melatonin level and mtDNA copy number change and damage in 13 opiate dependent females who received drug detoxification at 0,3 and 6 *** overall pattern in the drug abusers during abstinence was compared to that of 17 matched normal *** opiate abusers had a mean age of 31.7±2.4 years and were recruited from the Kunming Compulsory Drug Detoxification *** control group had a mean age of 30±1.7 years and had no history of medical,neurological or psychiatric *** melatonin level was quantified by enzyme-linked immunosorbent assay(ELISA).Quantitative real-time PCR was used to detect mtDNA copy number change and *** melatonin level,mtDNA copy number and mtDNA damage between the normal controls and drug abusers undergoing abstinence at different time points were compared by unpaired t *** also examined the time-dependent change of plasma melatonin level, mtDNA copy number change and damage in these drug abusers during drug abst

关键词： drug addiction melatonin mtDNA copy number mtDNA damage

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Brain Dynamic Mechanisms of Scale Effect In Visual Spatial A...

Using OCT image to distinguish human acupoint from non-acupoint tissues after irradiation with laser in vivo:a pilot study

中国医师协会第二届康复医学论坛、中国康复医学会第四届青年学术会议、北京康复医学会第三届会员代表大会

作者： SONG weiqun, LING feng, WANG Maobin, QIN yanjing, YANG yuanbin, LI guangqin LUO yuejia Department of rehabilitation, Xuanwu Hospital, Capital university of Medical Science, beijing, 100053, china. Key Laboratory of Mental Health, Institute of Psychology, chinese academy of sciences, beijing, china.

The dynamic mechanisms in the brain of the early ERP scale effect of different attentive regions was studied among 16 young subjects through the precue-target visual search paradigm by ERP technique, with the attentive regions cued by different scales of chinese characters. The results showed that the reaction time was shortened with the reduction of cue scale and fixed target stimulus, while the amplitudes of P1 and N1 components of event-related potentials increased. These results not only provided the electrophysiological evidences which supported the zoom-lens theory, but also indicated that the zoom-lens effect happened at the early selected attention period. The results also showed that there existed two kinds of separation in P2 effect. One was between P1 effect and P2 effect, which meant that additional computation was needed when the spatial scale of attention was enlarged;the other was between the left and right hemisphere of P2 effect, which indicated that the attentive processing of the cue region mainly happened in the left hemisphere.

关键词： Visual spatial attention, Scale effect, Event-related potential

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chinese Optics Letters 2010年第4期8卷 418-420页

作者：钟会清张祖德郭周义魏华江杨洪钦何永红谢树森刘颂豪 Key Laboratory of Laser Life Science of Ministry of Education of china South china Normal university Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education of china Fujian Normal university graduate School at Shenzhen Tsinghua university

Using the optical coherence tomography（OCT） images,the optical attenuation coefficients（μ_t） of human Laogong acupoint and non-acupoint tissues are measured after empty irradiation and 808-nm 100-mW irradiation for 10 min in vivo *** results show that there is no significant difference ofμ_t of Laogong acupoint and non-acupoint tissues after empty ***,there are significant differences ofμ_t between Laogong acupoint and non-acupoint tissues after laser irradiation at the power of 100 mW（statistical definition of probability p0.01）.The results of the pilot study indicate that the OCT could distinguish the acupoint from the surrounding tissues after irradiation with laser in vivo non-invasively.

关键词： Coherent light Electromagnetic wave attenuation Histology Irradiation Probability density function Radiation Tissue Tomography

用绿色荧光蛋白监测转基因植物中选择标记基因的消除

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生物工程学报 2004年第1期20卷 10-15页

作者：贾洪革吕玲飞庞永奇陈晓英方荣祥中国科学院微生物研究所植物生物技术实验室北京100080

绿色荧光蛋白 (GFP)可直接进行活体观察 ,它的这个优点可被用于监测转基因植物中选择标记基因的消除。为此 ,构建了植物表达载体pGNG ,将绿色荧光蛋白基因 (gfp)和卡那霉素抗性基因表达盒 (NosP nptII NosT)一起克隆在两个同向的lox位点... 详细信息

绿色荧光蛋白 (GFP)可直接进行活体观察 ,它的这个优点可被用于监测转基因植物中选择标记基因的消除。为此 ,构建了植物表达载体pGNG ,将绿色荧光蛋白基因 (gfp)和卡那霉素抗性基因表达盒 (NosP nptII NosT)一起克隆在两个同向的lox位点间 ,在第一个lox位点上游置有CaMV 35S启动子以驱动GFP表达 ,第二个lox位点下游置有不含启动子的大肠杆菌 β 葡萄糖醛酸酶 (GUS)基因。首先在含卡那霉素 (Kan)的培养基上筛选出转pGNG的烟草 ,借助绿色荧光可容易地检出表达GFP的转化体。然后用另一转化载体pCambia130 0 Cre二次转化表达GFP的转基因植物 ,利用另一选择标记基因潮霉素抗性基因 (hpt)进行筛选 ,在获得的再生植株中 ,Cre重组酶的表达消除了转化体中两lox位点间的gfp和nptII。实验结果表明可借助GFP荧光的消失 ,快速选出nptII被消除的二次转化体 ,同时GUS(作为目的蛋白 )在CaMV 35S启动子驱动下获得表达。最后利用后代的分离将hpt和cre除去。

关键词：选择标记基因转基因植物绿色荧光蛋白瞬间表达化学诱导表达

Recruitment of stem cells by hepatocyte growth factor via intracoronary gene transfection in the postinfarction heart failure

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Science china(Life sciences) 2007年第6期50卷 748-752页

作者： YANG ZhiJian1, WANG Wei1, MA DongChao1, ZHANG YouRong2, WANG LianSheng1, ZHANG YuQing1, XU ShunLin1, CHEN Bo1, MIAO DengShun3, CAO KeJiang1 & MA WenZhu1 1 Department of Cardiovascular Medicine, the First Affiliated Hospital of Nanjing Medical university, Nanjing 210029, china 2 Department of Experimental Hematology, beijing Institute of Radiation Medicine, beijing 100850, china 3 Department of Experimental anatomy, Nanjing Medical university, Nanjing 210029, china Department of Cardiovascular Medicine the First Affiliated Hospital of Nanjing Medical University Nanjing China Department of Experimental Hematology Beijing Institute of Radiation Medicine Beijing China Department of Experimental anatomy Nanjing Medical University Nanjing China

We aim to study the amelioration effect of adenovirus5-mediated human hepatocyte growth factor gene transfer on postinfarction heart failure in swine model. Twelve Suzhong young swine were randomly divided into 2 groups of 6 pigs each: Ad5-HGF group and mock-vector Ad5 group. Four weeks after ligation of the left anterior descending coronary artery, Ad5-HGF was intracoronarily transferred into the myocardium. Simultaneously, gate cardiac perfusion imaging was performed to evaluate the heart function. Three weeks later, gate cardiac perfusion imaging was performed again, then the hearts were removed and sectioned for immunohistochemical examination to illustrate the effects of Ad5-HGF on infarcted myocardium. The expression of HGF was examined by ELISA. The results were: (1) compared with the mock-vector Ad5 group, high expression of human HGF was observed in the myocardium of Ad5-HGF group; (2) in the Ad5-HGF group, the number of CD117+ cells co-expressing c-Met per mm2 was significantly larger; (3) the improvement in LVEF was greater in the Ad5-HGF group than in the mock-vector Ad5 group. We concluded that: (1) high expression of human HGF was observed in the myocardium through intracoronary gene transfection; (2) HGF can improve the mobilization of CD117+/c-Met+ stem cells into ischemic myocardium. The amelioration effect of HGF on postinfarction heart failure could not be limited to stimulating angiogenesis, anti-apoptosis, anti-fibrosis, but was also involved in the recruitment of stem cells into myocardium.

关键词： gene therapy, stem cells, postinfarction heart failure