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An Autopsy and Histopathology-based study to Ascertain the Cause of Death of Brought Dead Cases

Journal of Forensic science and Medicine 2024年第1期10卷 28-33页

作者： Chandan Bandyopadhyay Prabir chandra Paul Prabhas chandra Chakraborty Department of Forensic and state Medicine Medical CollegeKolkataWest BengalIndia Department of Pathology Jagannath Gupta Institute of Medical Science and HospitalKolkataWest BengalIndia Department of Forensic Medicine and Toxicology NRS Medical College and HospitalKolkataand M.G.M Medical College and L S.K HospitalKishanganjBiharIndia

Background and Objectives:The cases of apparent natural deaths are encountered in the hospital casualties who are noted dead at the time of the first medical attention and as such are labeled as“Brought Dead.”These include the cases of sudden death,unexplained death,and unattended *** cause of such deaths is reported in the literature to emanate principally from the cardiovascular system,though there are some documented geographical,racial,and other *** the present study,we endeavored to detect the cause of such natural deaths in terms of the disease and the organ system involved,in the deceased individuals of the contemporary Bengali population,with cases due to obvious unnatural causes being *** and Methods:An observational,cross-sectional study with 105(n=105,male:89,female:16)study subjects of age group of 20-80 years,selected by systemic random sampling,from the brought dead subjects coming to the mortuary of the NRs Medical College and Hospital for medicolegal autopsy from April 2011 to March 2012,excluding cases having a history of the obvious unnatural *** system-wise gross examination was done,followed by tissue sampling for histopathological *** case-wise findings were tabulated and analyzed for descriptive statistics using sPss ***:In the present study,89 cases were male(84.8%)and 16 cases were female(15.2%),which reflects a male:female ratio of 5.56:*** dead bodies are mostly recovered from the footpaths(47 cases,44%).sixty-four(61%)cases are of known *** 54 cases out of 105(51.4%),morbid pathology is detected in the respiratory system(Rs),lobar pneumonia,and cavitary pulmonary tuberculosis being the most frequent disease entity,in both ***-one years-sixty-five years is found to be the most commonly affected age group,in both *** and Conclusions:The present study shows that the most common organ system involved in brought dead cases is the Rs,which is s

关键词： Autopsy brought dead cause of death histopathology

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Fractional order prey-predator model incorporating immigration on prey:Complexity analysis and its control

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International Journal of Biomathematics 2024年第5期17卷 285-317页

作者： Md.Jasim Uddin chandra Nath Podder Departmentof Mathematics University of Dhaka Dhaka-1000Bangladesh

In this paper,the Caputo fractional derivative is assumed to be the prey-predator *** order to create Caputo fractional differential equations for the prey-predator model,a discretization process is first *** fixed points of the model are categorized *** identify requirements for the fixed points of the suggested prey-predator model's local asymptotic *** demonstrate analytically that,under specific parametric conditions,a fractional order prey-predator model supports both a Neimark-sacker(Ns)bifurcation and a Flip *** present evidence for Ns and Flip bifurcations using central manifold and bifurcation *** parameter values and the initial conditions have been found to have a profound impact on the dynamical behavior of the fractional order prey-predator *** the bifurcation parameter is increased,the system displays chaotic *** simulations are shown to demonstrate chaotic behaviors like bifurcations,phase portraits,invariant closed cycles,and attractive chaotic sets in addition to validating analytical *** suggested prey-predator dynamical system's chaotic behavior will be controlled by the OGY and hybrid control methodology,which will also visualize the chaotic state for various biological parameters.

关键词： Prey-predator model Caputo fractional derivative Flip and Neimark-sacker(Ns)bifurcations immigration chaos control numerical simulation

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Efficient processed carbon soot@Mos2 hybrid Bi-functional electrode for dye-sensitized solar cell and asymmetric supercapacitor devices

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Nano Materials science 2024年第4期6卷 484-494页

作者： B.Arjun Kumar gopal Ramalingam salah Addin Burhan Al Omari Zhumabay Bakenov sambasivam sangaraju sangarapani sudhakar Quantum Material Research Lab (QMRL) Department of Nanoscience and TechnologyAlagappa University Department of Mechanical and Aerospace Engineering United Arab Emirates University Department of Chemical and Materials Engineering Nazarbayev University National Water and Energy Center United Arab Emirates University Department of Physics Alagappa University

A feasible approach to rectify the world's energy demand using sustainable development of adequate energy generation and storage technologies in a single *** this respect,we made a holistic approach with a bifunctional electrode material to perform effectively in energy generation and storage ***2nanosheets were produced by the eco-friendly method and reduced graphene oxide is used to prepared by carbon soot which is derived from castor *** prepared soot and rGO were combined with Mos2nanosheets using a simple sonication *** as-prepared sample was introduced in the supercapacitor and DssC *** combination Mos2@rGO provides an enhanced conversion efficiency of 11.81%and the reproducibility of DssC is also ***,Mos2@rGO is used to fabricate an asymmetric supercapacitor to investigate its real-time *** device produced the maximum power density （1666.6 mW/kg） and energy density （25.69 mWh/Kg） at 1 A/*** asymmetric supercapacitor device holds a cyclic stability of 81.4%for 5000 cycles and it powered up an LED device for 4 min.

关键词： Carbon soot solar cells supercapacitors Mos 2 DssC

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The Determination of Heritability in palatal Rugae Pattern among Parents and their Off-springs in Western India-A Cross-sectional study

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Journal of Forensic science and Medicine 2024年第1期10卷 42-46页

作者： Aishwarya Bhatnagar sugandha Arya Jyothi s Kumar Aishwarya Arya Kailash chandra Morya sudhir Baroopal Department of Oral Medicine and Radiology Vyas Dental College and HospitalJodhpurRajasthanIndia Department of Conservative and Endodontics Vyas Dental College and HospitalJodhpurRajasthanIndia

Background:Palatal rugae are asymmetrical elevations present on hard palate and are significant due to their uniqueness,stability and thus,aid in forensic ***:The objective is to determine palatal rugae morphology between parents and their offsprings and to determine their genetic *** and Methods:This randomized controlled cross-sectional single-blinded study was conducted on 50 families(randomly selected)who visited Vyas Dental College and Hospital.A total of 150 maxillary study models were examined and rugae were delineated and shape,size,and pattern of rugae were ***:Weak but significant correlation was seen in the nonspecific and angular type of palatal rugae between child and mother and child and father as Ps seen for curved,wavy,divergent,straight,horseshoe,angular,and nonspecific type of rugae with the higher%of wavy pattern matching(52%with mother and 54%with father).A considerable number of samples showed high heritability of primary and secondary rugae from both parents,but more predominantly to their mothers(branched,nonspecific,and straight).Conclusion:Both environmental and genetic factors can influence the rugae ***,studies should be conducted on a larger sample size to get more significant results.

关键词： Forensic identification heredity palatal rugae uniqueness

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mRNA vaccines:a new era in vaccine development

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Oncology Research 2024年第10期32卷 1543-1564页

作者： sHUBHRA chandra JENNIFER C.WILsON DAVID GOOD MING Q.WEI school of Pharmacy&Medical sciences Gold Coast campusGriffith UniversityBrisbaneQLD-4222Australia Menzies Health Institute Queensland(MHIQ) Gold Coast CampusGriffith UniversityBrisbaneQLD-4215Australia school of Allied Health Australian Catholic UniversityBrisbaneQLD-4014Australia

The advent of RNA therapy,particularly through the development of mRNA cancer vaccines,has ushered in a new era in the field of *** article provides a concise overview of the key principles,recent advancements,and potential implications of mRNA cancer vaccines as a groundbreaking modality in cancer *** cancer vaccines represent a revolutionary approach to combatting cancer by leveraging the body’s innate immune *** vaccines are designed to deliver specific mRNA sequences encoding cancer-associated antigens,prompting the immune system to recognize and mount a targeted response against malignant *** personalized and adaptive nature of mRNA vaccines holds immense potential for addressing the heterogeneity of cancer and tailoring treatments to individual *** breakthroughs in the development of mRNA vaccines,exemplified by the success of COVID-19 vaccines,have accelerated their application in *** mRNA platform’s versatility allows for the rapid adaptation of vaccine candidates to various cancer types,presenting an agile and promising avenue for therapeutic *** trials of mRNA cancer vaccines have demonstrated encouraging results in terms of safety,immunogenicity,and *** candidates,such as BioNTech’s BNT111 and Moderna’s mRNA-4157,have exhibited promising outcomes in targeting melanoma and solid tumors,*** successes underscore the potential of mRNA vaccines to elicit robust and durable anti-cancer immune *** the field holds great promise,challenges such as manufacturing complexities and cost considerations need to be addressed for widespread *** development of scalable and cost-effective manufacturing processes,along with ongoing clinical research,will be pivotal in realizing the full potential of mRNA cancer ***,mRNA cancer vaccines represent a cutting-edge therapeutic approach that holds the promise of transforming cancer treatment.

关键词： Cancer immunotherapy Immune checkpoint Preventive&therapeutic vaccine Delivery system mRNA

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Dual-wavelength all-fiber Q-switched fiber laser using bismuth-doped fiber as saturable absorber

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Optoelectronics Letters 2024年第3期20卷 147-151页

作者： Aruna Ghosh Abdulkadir Mukhtar Diblawe Uttam Kumar samanta Moh Yasin sulaiman Wadi Harun Mukul chandra Paul Fiber Optics and Photonics Division CSIR-Central Glass and Ceramic Research InstituteKolkata 700032India Physics Department Jadavpur UniversityKolkata 700032India Photonics Engineering Laboratory Department of Electrical EngineeringUniversity of MalayaKuala Lumpur 50603Malaysia Department of Physics Faculty of Science and TechnologyAirlangga UniversitySurabayaIndonesia

A passively Q-switched all-fiber laser is demonstrated using a 10-cm-long bismuth-doped fiber(BDF) as a saturable absorber(sA). The dual-wavelength operation was obtained due to the nonlinear effect inside the fabricated BDF, which has a high germanium content. stable Q-switched pulses were obtained at the dual synchronous wavelengths of 1 530.1 nm and 1 531.1 nm. When the pump power is tuned from 105.3 mW to 191.0 mW, the repetition rate can be varied from 82.6 kMz to 117.6 kHz. The maximum pulse energy and average output power were 83.4 nJ and 9.8 mW, respectively while the minimum pulse width was 8.5 μs at the maximum pump power of 191.0 mW. Our results indicate that BDF could be a promising alternative optical modulator for pulsed fiber laser application.

关键词： fiber switched pump

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Non-Newtonian Flow of Blood in a Catheterized Bifurcated stenosed Artery

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Journal of Bionic Engineering 2018年第1期15卷 173-184页

作者： Jagadis chandra Misrat gopal chandra shit Ranjan Pramanik Centre for Healtheare science and Technology Indian Institute of Engineering Science and Technology Shibpur 711103 lndia Department of Mathematics Jadavpur University Kolkata 700032 India Department of Mathematics Indian Institute of Technology Kharagpur 721302 lndia

The paper is devoted to study the non-Newtonian behavior of blood flowing in an artery having a stenosis, in a situation when a catheter has been inserted into it. The blood rheology is described by Herschel-Bulkley fluid model. The flow configuration is con- structed by choosing suitable curvature at the lateral junction, where the flow separation is initiated. The effects of insertion of catheter and that of yield stress of blood on the velocity distribution, rate of flow and flow resistance of blood, distribution of shear stress at the arterial wall and the location of yield plane are investigated. The results provide some useful information for the prediction/treatment of some arterial diseases and circulatory disorders of the cardiovascular system, in a situation, when a stenosis is developed on the endothelium of the daughter artery / bifurcated artery. The study reveals that if the ratio between the radii of the catheter and the artery is increased, the shear stress at the arterial wall diminishes. However, when the bifurcation angle is increased, the wall shear stress is enhanced.

关键词： Herschel-Bulkley fluid model arterial bifurcation catheterized artery yield plane flow resistance

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Network analyses:Inhibition of androgen receptor signaling reduces inflammation in the lung through AR-MAF-IL6 signaling axes

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Genes & Diseases 2024年第3期11卷 140-143页

作者： Albert R.Wang Andrew M.Baschnagel Zijian Ni sean R.Brennan Hypatia K.Newton Darya Buehler Christina Kendziorski Randall J.Kimple gopal lyer Department of Human Oncology University of Wisconsin School of Medicine and Public HealthUniversity of WisconsinMadisonWI 53705USA Department of Biomedical Engineering University of Wisconsin-MadisonMadisonWI 53705USA University of Wisconsin Carbone Cancer Center MadisonWI 53705USA Department of Biostatistics and Medical Informatics University of Wisconsin-MadisonMadisonWI 53706USA Department of Biology Tufts UniversityMedfordMA 02155USA Department of Pathology and Laboratory Medicine University of Wisconsin School of Medicine and Public HealthUniversity of WisconsinMadisonWI 53705USA

Androgen receptor(AR)is a major transcription factor that plays a role in inflammatory response including interleukin-6(IL6)signaling.1 While AR regulation through paracrine loop signaling in prostate tissue is well-studied,its impact through an IL6 autocrine loop in the lung has not been wellstudied despite the organ's response to respiratory viral *** inhibition and RNA knockdown of AR identified a bZIP transcription factor MAF to be a common target of inflammation using these perturbations in lung cells.

关键词： inflammation lung respiratory

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Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates

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Genes & Diseases 2024年第1期11卷 34-37页

作者： Budhadev Baral Dharmendra Kashyap Nidhi Varshney Tarun Prakash Verma Ajay Kumar Jain Debi Chatterji Vinod Kumar Amit Mishra Awanish Kumar Hem chandra Jha Infection Bioengineering Group Department of Biosciences and Biomedical EngineeringIndian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Choithram Hospital and Research Center IndoreMadhya Pradesh452014India Department of Metallurgy Engineering and Materials science Indian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Department of Bioscience&Bioengineering Indian Institute of Technology JodhpurNH 65 Nagaur RoadJodhpur DistrictKarwarRajasthan 342037India Department of Biotechnology National Institute of Technology RaipurGE RoadRaipurChhattisgarh 492010India

Persistent gastritis induced by Helicobacter pylori(***)is the strongest known risk factor for gastric cancer(GC).*** is prevalent in about 50%world's population,while it causes cancer in less than 2%of exposed individuals.1 Our studies found that *** infection can induce oncogenic properties in AGs cells by deregulating multiple factors associated with the cell cycle,apoptosis,and other important events associated with cancer progression.

关键词： H.pylori pylori Helicobacter

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Electro-magnetohydrodynamic Flow of Biofluid Induced by Peristaltic Wave： A Non-newtonian Model

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Journal of Bionic Engineering 2016年第3期13卷 436-448页

作者： gopal chandra shit Nayan Kumar Ranjit Aniruddha sinha Department of Mathematics Jadavpur University Kolkata - 700032 India Yogoda satsanga Palpara Mahavidyalaya Purba Medinipur - 721458 India

This article aims to develop a mathematical model for peristaltic transport of magnetohydrodynamic flow of biofluids through a micro-channel with rhythmically contracting and expanding walls under the influence of an applied electric field. The couple stress fluid model is considered to represent the non-Newtonian characteristics ofbiofluids. The velocity slip condition at the channel walls is taken into account because of the hyclrophilic/hydrophobic interaction with negatively charged walls. The essential features of the electromagnetohydrodynamic flow of biofluid through micro-channels are clearly highlighted in the variations of the non-dimensional parameters of the physical quantities of interest such as the velocity, wall shear stress, pressure gradient, pressure rise per wave length, frictional force at the channel walls and the distribution of stream function. It reveals that the flow ofhiofluid is appreciably influenced by the sufficient strength of externally applied magnetic field and electro-osmotic parameter. The velocity slip condition reduces the frictional force at the channel wall. Moreover, the formation of the trapping bolus strongly depends on electro-osmotic parameter and magnetic field strength.

关键词： peristaltic transport couple stress fluid magnetohydrodynamics electro-osmosis

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