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Cellular & Molecular Immunology 2018年第7期15卷 727-730页

作者： Andrea Pennati Seneshaw Asress Jonathan d glass Jacques Galipeau department of Medicine University of Wisconsin School of Medicine and Public Health and University of Wisconsin Carbone Cancer CenterMadisonWI 53706USA department of Neurology Emory UniversityAtlantaGA 30322USA

I mmunosuppressive therapies have meaningful effects on the treatment of multiple sclerosis(MS),a classical inflammatory autoimmune disease of the central nervous system.1 In mice with experimental autoimmune encephalomyelitis(EAE),a murine model of human MS,we showed that an adoptive transfer of GM-CSF and Interleukin-15 Fusion Transgene(GIFT15)-derived regulatory B cells(GIFT15 Bregs)sustained a durable remission of the disease.2,3 These regulatory B cells require the expression of MHC class II and IL-10 for suppressive activity.

关键词： sustained sclerosis autoimmune

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催化重整和异构化

石油炼制译丛 1989年第6期 6-10页

作者： glass,d 董福根

雌二醇和孕酮对乏情母羊GnRH免疫反应神经元系统的影响

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草食家畜 1988年第2期 26-28页

作者： J.d.glass 王刚牛

温带哺乳动物的繁殖周期是通过性类固醇对促性腺激素分泌的反馈控制来调节的。例如,用正常剂量的17β-雌二醇（E;）持续处理切除了卵巢的母羊,可引起血液中促黄体素（LH）浓度的季节性波动。这可能是由于在非繁殖季节中,下丘脑—垂体轴... 详细信息

温带哺乳动物的繁殖周期是通过性类固醇对促性腺激素分泌的反馈控制来调节的。例如,用正常剂量的17β-雌二醇（E;）持续处理切除了卵巢的母羊,可引起血液中促黄体素（LH）浓度的季节性波动。这可能是由于在非繁殖季节中,下丘脑—垂体轴对性类固醇激素的敏感性增加所致。E;的这种负反馈调节活动的神经内分泌原理尚不清楚。

关键词： GnRH ME 下丘脑间脑母羊细胞化学神经元系统放免测定雌二醇雌激素孕酮孕激素免疫反应

Role of leptin in the progression of psoriatic,rheumatoid and osteoarthritis

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World Journal of Rheumatology 2016年第1期6卷 9-15页

作者： Jessica Mounessa Iryna Voloshyna Amy d glass Allison B Reiss Winthrop Research Institute and department of Medicine Winthrop-University HospitalSUNY Stony Brook School of Medicine

Leptin,an adipokine responsible for body weight regulation,may be involved in pathological processesrelated to inflammation in joint disorders including rheumatoid arthritis(RA),osteoarthritis,and psoriatic arthritis(PsA).These arthropathies have been associated with a wide range of systemic and inflammatory con-ditions including cardiovascular disease,obesity,and metabolic *** a potent mediator of immune responses,leptin has been found in some studies to play a role in these ***,current potent biologic treatments effectively used in Ps A including ustekinumab(an interleukin 12/23 blocker) and ada-limumab(a tumor necrosis factor-alpha blocker also used in RA) have been found to increase leptin receptor expression in human *** literature review aims to further investigate the role leptin may play in the disease activity of these arthropathies.

关键词： Psoriatic arthritis Rheumatoid arthritis Leptin Ustekinumab Tumor necrosis factor-alpha

Snapshot imaging of ultrashort electron bunches

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Light(Science & Applications) 2024年第7期13卷 1226-1228页

作者： Andreas döpp Ludwig-Maximilian-Universität München Am Coulombwall 185748GarchingGermany Max Planck Institut für Quantenoptik Hans-Kopfermann-Strasse 1Garching85748Germany

New measurements combine spatial and temporal information from optical transition radiation to estimate the three-dimensional structure of electron bunches from a laser wakefield accelerator.

关键词： ultrashort Snapshot electron

Influence of variable viscosity and double diffusion on the convective stability of a nanofluid flow in an inclined porous channel

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Applied Mathematics and Mechanics(English Edition) 2024年第3期45卷 563-580页

作者： N.HUMNEKAR d.SRINIVASACHARYA department of Mathematics National Institute of TechnologyWarangal 506004TelanganaIndia

The influence of variable viscosity and double diffusion on the convective stability of a nanofluid flow in an inclined porous channel is *** darcyBrinkman model is used to characterize the fluid flow dynamics in porous *** analytical solutions are obtained for the unidirectional and completely developed *** on a normal mode analysis,the generalized eigenvalue problem under a perturbed state is *** eigenvalue problem is then solved by the spectral ***,the critical Rayleigh number with the corresponding wavenumber is evaluated at the assigned values of the other flow-governing *** results show that increasing the darcy number,the Lewis number,the dufour parameter,or the Soret parameter increases the stability of the system,whereas increasing the inclination angle of the channel destabilizes the ***,the flow is the most unstable when the channel is vertically oriented.

关键词： nanofluid inclined channel variable viscosity linear stability double dif-fusion porous medium

Improved Leap-frog Method for Time-domain Fault Location

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Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 670-674页

作者： Izudin džafić Rabih A.Jabr Faculty of Electrical Engineering University of SarajevoSarajevo 71000Bosnia and Herzegovina department of Electrical and Computer Engineering American University of BeirutBeirut 11072020Lebanon IEEE

The partial differential equation(PdE)solution of the telegrapher is a promising fault location method among time-domain and model-based *** research works have shown that the leap-frog process is superior to other explicit methods for the PdE ***,its implementation is challenged by determining the initial conditions in time and the boundary conditions in *** letter proposes two implicit solution methods for determining the initial conditions and an analytical way to obtain the boundary conditions founded on the signal *** results show that the proposal gives fault location accuracy superior to the existing leap-frog scheme,particularly in the presence of harmonics.

关键词： Fault location leap-frog partial differential equation time-domain analysis transmission line

The Effect of External Magnetic Field on Electron Scale Kelvin–Helmholtz Instability

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Research in Astronomy and Astrophysics 2024年第9期24卷 236-247页

作者： d.Tsiklauri Joule Physics Laboratory School of ScienceEngineering and EnvironmentUniversity of SalfordManchesterM54WTUK

We use particle-in-cell,fully electromagnetic,plasma kinetic simulation to study the effect of external magnetic field on electron scale Kelvin–Helmholtz instability(ESKHI).The results are applicable to collisionless plasmas when,e.g.,solar wind interacts with planetary magnetospheres or a magnetic field is generated in AGN *** find that as in the case of magnetohydrodynamic(MHd)KHI,in the kinetic regime,the presence of an external magnetic field reduces the growth rate of the *** the MHd case,there is a known threshold magnetic field for KHI stabilization,while for ESKHI this is to be analytically *** a kinetic analytical expression,we use several numerical simulation runs to establish an empirical dependence of ESKHI growth rate,Γ(B_(0))ω_(pe),on the strength of the applied external magnetic *** find the best fit is hyperbolic,Γ(B_(0))ω_(pe)=Γ_(0)ω_(pe)/(A+BB_(0)),where Γ_(0) is the ESKHI growth rate without an external magnetic field and B_(0)=B_(0)/B_(MHd)is the ratio of external and two-fluid MHd stability threshold magnetic field,derived *** analytical theory to back up this growth rate dependence on the external magnetic field is *** results suggest that in astrophysical settings where a strong magnetic field pre-exists,the generation of an additional magnetic field by the ESKHI is suppressed,which implies that nature provides a“safety valve”—natural protection not to“over-generate”magnetic field by the ESKHI ***,we find that our two-fluid MHd threshold magnetic field is the same(up to a factor √γ_(0))as the dC saturation magnetic field,previously predicted by fully kinetic theory.

关键词： instabilities magnetic fields plasmas Sun:heliosphere ISM:magnetic fields

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东京也将建成纽约式的高线公园

商业周刊（中文版） 2024年第9期 34-36页

作者： Mia glass 孟洁冰(译) 不详

东京即将建造类似于纽约高线公园的高架步行道,标志着这座城市对汽车至上地位的重视发生了初步转变。日本首都东京中心地带的一条主要高速道路计划把部分路段迁移至地下,这个项目将削弱东京高速道路(又称KK线)的重要地位。在讨论是否拆... 详细信息

东京即将建造类似于纽约高线公园的高架步行道,标志着这座城市对汽车至上地位的重视发生了初步转变。日本首都东京中心地带的一条主要高速道路计划把部分路段迁移至地下,这个项目将削弱东京高速道路(又称KK线)的重要地位。在讨论是否拆除KK线的事宜后,东京于2021年决定将这条长2公里的道路改造为空中步行道。该项目将于2029年部分开放,计划于2030年代或2040年代全部完工。

关键词：高速道路高线公园道路改造东京纽约步行

decomposition mechanisms of nuclear-grade cationic exchange resin by advanced oxidation processes:Statistical molecular fragmentation model and dFT calculations

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Journal of Environmental Sciences 2024年第1期135卷 433-448页

作者： Xiang Meng Pierre désesquelles Lejin Xu department of Nuclear Engineering and Technology School of Energy and Power EngineeringHuazhong University of Science&TechnologyWuhan 430074China CNRS Laboratoire de Physique des Gaz et des PlasmasUniversitéParis-SaclayOrsay 91405France State Key Laboratory of Coal Combustion School of Energy and Power EngineeringHuazhong University of Science and TechnologyWuhan 430074China

The treatment and disposal of radioactive waste are presently facing great *** ion exchange resins have become a focus of attention due to their high production and serious environmental *** this paper,a simplified model of cationic exchange resin is proposed,and the degradation processes of cationic resin monomer initiated by hydroxyl radicals(·OH)are clarified by combining statistical molecular fragmentation(SMF)model and density functional theory(dFT)*** prediction of active sites indicates that the S-O bonds and the C-S bond of the sulfonic group are more likely to react during the *** meta-position of the sulfonic group on the benzene ring is the most active site,and the benzene ring without the sulfonic group has a certain *** C11-C14 and C17-C20 bonds,on the carbon skeleton,are the most easily *** is also found that dihydroxy addition and elimination reactions play a major role in the process of desulfonation,carbon skeleton cleavage and benzene ring *** decomposition mechanisms found through the combination of physical models and chemical calculations,provide theoretical guidance for the treatment of complex polycyclic aromatic hydrocarbons.

关键词： Cationic exchange resin Statistical molecular fragmentation model density functional theory Hydroxyl radical decomposition mechanism